The present invention provides an organic light emitting device array which reduces the change of white balance even if an observation angle is changed. In an organic light emitting device array comprising a plurality of organic light emitting devices which emit lights of different colors, an optical path difference is set such that signs of gradients at an optical path difference of 2 L of interferograms for all the plurality of organic light emitting devices are identical to each other.
According to an embodiment, a semiconductor light emitting device is configured to emit light by energy relaxation of an electron between subbands of a plurality of quantum wells. The device includes an active layer and at least a pair of cladding layers. The active layer is provided in a stripe shape extending in a direction parallel to an emission direction of the light, and includes the plurality of quantum wells; and the active layer emits the light with a wavelength of 10 μm or more. Each of the cladding layers is provided both on and under the active layer respectively and have a lower refractive index than the active layer. At least one portion of the cladding layers contains a material having a different lattice constant from the active layer and has a lower optical absorption at a wavelength of the light than the other portion.
The disclosed system, device and method for molecular-scale electronic switching generally includes a carbon nanotube, an anode, a cathode and two conductive particles encapsulated within the carbon nanotube, wherein the particles are configured to move between high resistance and low resistance states. Disclosed features and specifications may be variously controlled, adapted or otherwise optionally modified to realize improved switching function.
A phase change memory device that utilizes a nanowire structure. Usage of the nanowire structure permits the phase change memory device to release its stress upon amorphization via the minimization of reset resistance and threshold resistance.
A memory cell including a via made of a phase-change material arranged between a lower electrode and an upper electrode, wherein the via includes a first region adjacent to a second region itself adjacent to at least one third region, the first, second, and third regions each extending from the upper electrode to the lower electrode, the crystallization temperature of the second region ranging between that of the first region and that of the third region, and the melting temperatures of the first, second, and third regions being substantially identical.
Some embodiments include methods of forming memory cells. An opening is formed over a first conductive structure to expose an upper surface of the first conductive structure. The opening has a bottom level with a bottom width. The opening has a second level over the bottom level, with the second level having a second width which is greater than the bottom width. The bottom level of the opening is filled with a first portion of a multi-portion programmable material, and the second level is lined with the first portion. The lined second level is filled with a second portion of the multi-portion programmable material. A second conductive structure is formed over the second portion. Some embodiments include memory cells.
Articles of manufacture and a method of how to utilize the same in order to create a radiation shielding barrier wall assembly. A metal stud and a metal support bar and a metal restraining bar and a prefabricated radiation shielding lead panel whereby the assembly of these components in the manner as directed and in conjunction with commercially available preexisting metal stud components will result in all radiation shielding lead panels overlapping at all interior field joints, and will result in no punctures or damage in any way to the radiation shielding lead created by the attachment method, creating a radiation shielding leak-proof metal stud system.
A chamber apparatus used with an external apparatus having an obscuration region may include: a chamber in which extreme ultraviolet light is generated; a collector mirror provided in the chamber for collecting the extreme ultraviolet light; a support for securing the collector mirror to the chamber; and an output port provided to the chamber for allowing the extreme ultraviolet light collected by the collector mirror to be introduced therethrough into the external apparatus.
Ion implant apparatus using a drum-type scan wheel holds wafers with a total cone angle less than 60°. A collimated scanned beam of ions, for example H+, is directed along a final beam path which is at an angle of at least 45° to the axis of rotation of the scan wheel. Ions are extracted from a source and accelerated along a linear acceleration path to a high implant energy (more than 500 keV) before scanning or mass analysis. The mass analyzer may be located near the axis of rotation and unwanted ions are directed to an annular beam dump which may be mounted on the scan wheel.
During ion implantation into a wafer, an ion beam current is measured, a change in vacuum conductance which changes in accordance with a change of the location of a structure operating in a vacuum beam line chamber or a vacuum treatment chamber is obtained, furthermore, changes in degree of vacuum at one or plural places are detected using a vacuum gauge installed in the vacuum beam line chamber or the vacuum treatment chamber. The amount of an ion beam current is corrected using the obtained vacuum conductance and the detected degree of vacuum at one or plural places, and the dose amount implanted into the wafer is controlled.
Naphthalene, benzene, toluene, xylene, and other volatile organic compounds have been identified as serious health hazards. This is especially true for personnel working with JP8 jet fuel and other fuels containing naphthalene as well as other hazardous volatile organic compounds (VOCs). Embodiments of the invention are directed to methods and apparatus for near-real-time in-situ detection and accumulated dose measurement of exposure to naphthalene vapor and other hazardous gaseous VOCs. The methods and apparatus employ excitation of fluorophors native or endogenous to compounds of interest using light sources emitting in the ultraviolet below 300 nm and measurement of native fluorescence emissions in distinct wavebands above the excitation wavelength. The apparatus of some embodiments are cell-phone-sized sensor/dosimeter “badges” to be worn by personnel potentially exposed to naphthalene or other hazardous VOCs. The badge sensor of some embodiments provides both real time detection and data logging of exposure to naphthalene or other VOCs of interest from which both instantaneous and accumulated dose can be determined. The badges employ a new native fluorescence based detection method to identify and differentiate VOCs. The particular focus of some embodiments are the detection and identification of naphthalene while other embodiments are directed to detection and identification of other VOCs like aromatic hydrocarbons such as benzene, toluene, and xylene.
Method and apparatus for producing an image associated with a biological sample is disclosed. A processor focuses on a portion of the biological sample based on fluorescence of a first fluorescent material and captures an image of the portion of the biological sample based on fluorescence of the first fluorescent material and the second fluorescent material.
A body module of an optical measurement instrument includes: a reception device (201) for receiving samples, a first plate (202), a second plate (203) substantially parallel with the first plate and movably supported relative to the first plate in a direction perpendicular to the first and second plates, and walls extending from outer edges of the first plate to outer edges of the second plate. The reception device is located in a measurement chamber constituted by the walls and the first and second plates. At least the second plate includes a fastening interface provided with an aperture. The fastening interface is suitable for an optical module to be mounted to the second plate. The measuring chamber provides protection against undesired stray light from surroundings. The movability of the second plate allows adjustment of a distance between a sample and an optical module mounted to the second plate.
In one embodiment an ion source includes an arc chamber and an emitter having a surface disposed in the arc chamber, where the emitter is configured to generate a plasma in the arc chamber. The ion source further includes a repeller having a repeller surface positioned opposite the emitter surface, and a hollow cathode coupled to the repeller and configured to provide a feed material into the arc chamber.
A radiological image-capturing device includes: a first read control section that executes a first read mode in which electric signals stored in a plurality of pixels are read out simultaneously in units of a plurality of rows; and an emission-start determining section that determines that the emission of radiation from a radiation source onto an image-capturing panel has started when the values of the electric signals read by the first read control section have become greater than an arbitrarily settable threshold. If it is determined by the emission-start determining section that the emission of said radiation has started, the first read control section terminates the reading of the electric signals, and thereby brings the image-capturing panel into an exposure state.
A stacked-type detection apparatus including a plurality of pixels arranged at small intervals is configured to have low capacitance associated with signal lines and/or driving lines. With this novel configuration, small time constant and high-speed driving capability can be achieved in the signal lines and/or driving lines. The plurality of pixels in the detection apparatus are arranged in a row direction and a column direction on an insulating substrate. Each pixel includes a conversion element and a switch element, the conversion element is disposed above the switch element. A driving line disposed below the conversion elements is connected to switch elements arranged in the row direction, and a signal line is connected to switch elements arranged in the column direction. The signal line includes a conductive layer embedded in an insulating member, the insulating member is disposed in a layer lower than an uppermost surface portion of the driving line.
The present invention provides a radiographic imaging including, provided at an insulating substrate, sensor portions for radiation detection that generate charges due to receive radiation or light converted from radiation, first signal lines that are connected to the sensor portions for radiation detection and through which flow electric signals that correspond to the charges generated at the sensor portions for radiation detection, and second signal lines having a substantially same wiring pattern as the first signal lines. Detection of radiation is carried out on the basis of a difference between an electric signal flowing through the first signal line and an electric signal flowing through the second signal line, or a difference between values of digital data obtained by digitally converting an electric signal flowing through the first signal line and an electric signal flowing through the second signal line, respectively.
A terahertz spectrometer having a wider range of terahertz radiation source, high temporal resolution of scanning (<0.0.099 μm or ˜0.3 pico second) over a wider range of scanning (up to ˜100 pico seconds). Also disclosed are exemplary applications of the spectrometer in biomedical, biological, pharmaceutical, and security areas.
An infrared light detecting device and the infrared detecting method thereof. The device comprises a shield, a first photo detector and a second photo detector. The shield for blocking light is located above the first photo detector and the second photo detector. An opening is disposed on the shield above the first photo detector. In addition, there is a gap arranged between the first photo detector and the second photo detector. The first photo detector can detect the light passing through the opening to generate a photo sensing signal and couple an infrared light signal in the photo sensing signal to the second photo detector in order to output the infrared light signal.
A TeraMOS sensor based on a CMOS-SOI-MEMS transistor, thermally isolated by the MEMS post-processing, designed specifically for the detection of THz radiation which may be directly integrated with the CMOS-SOI readout circuitry, in order to achieve a breakthrough in performance and cost. The TeraMOS sensor provides a low-cost, high performance THz passive or active imaging system (roughly in the range of 0.5-1.5 THz) by combining several leading technologies: Complementary Metal Oxide Semiconductor (CMOS)-Silicon on Insulator (SOI), Micro Electro Mechanical Systems (MEMS) and photonics. An array of TeraMOS sensors, integrated with readout circuitry and driving and supporting circuitry provides a monolithic focal plane array or imager. This imager is designed in a commercial CMOS-SOI Fab and the MEMS micromachining is provided as post-processing step in order to reduce cost. Thus the CMOS transistors and technology provide the sensors as well as the signal processing and additional readout circuitry both in the pixels as well as around the sensor array.
A Fourier transform infrared spectrometer includes a beam splitter (22), end mirrors (21, 23), one of which may be scanned, and detectors (32) detecting the interfered light at the two outputs of a beam combiner (22), which may be the same optical element as the beam splitter (22). Time records of detector samples may be transformed by Fourier transform to obtain the corresponding spectra. The detectors (32) may be sampled alternately in time and the samples subsequently interleaved to provide an increased effective sampling rate. The detectors (32) may be masked by color filter mosaics so that each pixel of each detector is sensitive only to one color of light, and the spectra obtained from pixels detecting different colors may be concatenated.
A terahertz-wave generating device including an optical waveguide containing an electrooptic crystal includes: first and second optical waveguides through which first and second light beams respectively propagate; a propagation portion through which a first terahertz wave propagates, the first terahertz wave being generated from the second optical waveguide in a direction different from a direction of the second light beam; and a delay portion arranged at incidence sides of the first and second light beams and configured to delay the first light beam relative to the second light beam. The first optical waveguide and the second optical waveguide are arranged with the propagation portion interposed therebetween. A first equiphase surface of the first terahertz wave is substantially aligned with a second equiphase surface of a second terahertz wave generated from the first optical waveguide in a direction different from a direction of the first light beam.
Provided is an air supply tube including an inlet port that takes in air, an outlet port that is arranged opposite a portion of an elongated target structure in a longitudinal direction, to which air taken in from the inlet port is to be supplied, and has an elongated opening shape, a channel portion in which a channel space for allowing air to flow between the inlet port and the outlet port is formed, and plural suppressing portions that suppress the flow of air, wherein the plural suppressing portions include at least a most downstream suppressing portion, a first upstream suppressing portion that is provided in a part initially located on the upstream side in the air flow direction, and a gap regulating portion that forms an extended gap at the same interval.
A method for processing a sample in a charged-particle beam microscope. A sample is collected from a substrate and the sample is attached to the tip of a nanomanipulator. The sample is optionally oriented to optimize further processing. The nanomanipulator tip is brought into contact with a stabilizing support to minimize drift or vibration of the sample. The attached sample is then stabilized and available for preparation and analysis.
The present invention relates generally to the field of ion storage and analysis, in particular to a linear ion trap mass analyzer comprised by multiple columnar electrodes. High frequency voltages are applied on at least one of the columnar electrodes to form ion confining space, which mainly consists of two-dimensional quadrupole electric radial trapping field, and there is at least one through slot for ion ejection in at least one direction perpendicular to the axis of the ion trap, wherein an AC electric field superposition is applied to invoke dipole excitation. Opposite to the through slot, there is an elongated electrode for field adjusting between two columnar electrodes or inside the slit of one of the columnar electrodes mentioned above. The potential on the elongated electrode for field adjusting is set as the sum of a portion of the high frequency voltage which applied on one adjacent columnar electrode and a DC offset, which can be adjusted freely. Through adjusting the portion of the high frequency potential and DC potential on this electrode, one or more objectives, including field optimization inside the ion trap as well as ion motion characteristics of resonant ejection, can be realized.
A ion source for a mass spectrometer comprises: a capillary having a nozzle for emitting a nebulized fluid sample; an electrode of the capillary; a high voltage power supply; a second electrode disposed within or configurable to be disposed within a path of the nebulized fluid sample; and at least one switch for selecting application of an electrical potential provided by the high voltage power supply to either or both of the capillary electrode or the second electrode, wherein the capillary and capillary electrode are configurable so as to ionize the nebulized fluid sample by electrospray ionization and the second electrode is configurable so as to ionize the nebulized sample by atmospheric pressure chemical ionization.
A time-of-flight mass spectrometer includes a holder that holds a sample, an irradiation unit that irradiates a surface of the sample with primary ions, an extractor electrode that opposes the sample, and an ion detector that detects a secondary ion emitted from the surface of the sample in accordance with a time of flight of the secondary ion. The surface of the sample has first and second positions, and the irradiation unit and the holder are disposed so that the primary ions are obliquely incident upon the surface of the sample. A primary ion reaches the first position before another primary ion reaches the second position. A potential gradient generator generates a potential gradient so that a potential difference between the second position and the extractor electrode is larger than a potential difference between the first position and the extractor electrode.
A method for assaying one or more immunosuppressant drug analytes in a sample derived from whole blood comprises: (a) passing the sample dissolved in a mobile phase through a length of 30 mm or less of a stationary phase of a reversed-phase chromatographic column; (b) eluting the separated analytes from the reversed-phase chromatographic column; (c) ionizing molecules of the eluted separated analytes by a heated electrospray ionization source of a mass spectrometer so as to generate a plurality of precursor ion species; (d) isolating, for each analyte, a respective one of the precursor ion species; (e) fragmenting ions of each of the isolated precursor ion species in a fragmentation cell of the mass spectrometer so as to generate a plurality of product ions therefrom; and (f) detecting, for each analyte, the presence and quantity of a respective one of the product ion species using a detector of the mass spectrometer.
A column circuit for an image sensor includes a first column read circuit configured to read data of a first column line, and a second column read circuit configured to read data of a second column line, wherein, during a binning mode, data from two or more pixels are outputted through the first column line and stored in the first column read circuit in a first phase, data from two or more pixels are outputted through the second column line and stored in the second column read circuit in a second phase, and charges are shared between the first column read circuit and the second column read circuit in a third phase.
Embodiments of the present invention are directed to autofocus subsystems within optical instruments that continuously monitor the focus of the optical instruments and adjust distances within the optical instrument along the optical axis in order to maintain a precise and stable optical-instrument focus at a particular point or surface on, within, or near a sample. Certain embodiments of the present invention operate asynchronously with respect to operation of other components and subsystems of the optical instrument in which they are embedded.
A temperature control device which can control the temperature of an object to be processed even after supply of radio waves or electromagnetic waves from a high-frequency heating apparatus is stopped. The temperature control device includes a temperature sensor detecting the temperature of the object to be processed heated by radio waves generated from the high-frequency heating apparatus, a signal processing circuit comparing the temperature detected by the temperature sensor with a standard temperature, a rechargeable battery charged by electric energy generated by reception of the radio waves by an antenna, a charging circuit controlling charging of the rechargeable battery, and a heater supplied with electric power from the rechargeable battery to heat the object to be processed so that the temperature thereof gets closer to the standard temperature, in accordance with a comparison result by the signal processing circuit.
Systems and methods for low voltage detection for a heat pump water heater are disclosed. A current sensor can be used to monitor current supplied to a inductive load, such as a compressor or evaporator fan, of the heat pump water heater. The current sensor can be coupled to a controller which receives and processes information from the current sensor to determine whether a low voltage condition of the heat pump water heater has occurred. An alert can be provided to an installer/user of the heat pump water heater that a low voltage condition has occurred. The controller can also disconnect the heat pump water heater from the power source to prevent damage to the heat pump water heater.
An actively heated mug or travel mug is provided. The mug or travel mug can include a body that receives a liquid therein and a heating system at least partially disposed in the body. The heating system can include one or more heating elements that heat a surface of the receiving portion of the body and one or more energy storage devices. The mug or travel mug can include a wireless power receiver that wirelessly receives power from a power source and control circuitry configured to charge one or more power storage elements and to control the delivery of electricity from the one or more power storage elements to the one or more heating elements. The mug or travel mug also can have one or more sensors that sense a parameter of the liquid or sense a parameter of the heating system and communicates the sensed information to the control circuitry. The control circuitry can turn on, turn off, and/or operate the heating element to actively heat at least a portion of the body to maintain the liquid in a heated state generally at a user selected temperature setting based at least in part on the sensed parameter information. The mug or travel mug can also be paired with a remote device or mobile electronic device to send or receive communications or commands.
A tortilla warmer control system is disclosed for controlling preparation and dispensing of tortillas. The control system includes a control unit capable of receiving inputs from a user, and providing outputs. The control unit receives user inputs including: a frequency of heating sessions, a number of tortillas to be heated and dispensed during each heating session; and tortilla texture. The control unit provides outputs including: a speed at which tortillas are to be conveyed through a heating sub-system of the tortilla warmer, and/or a temperature to be provided during each heating session; and a heating session initiation signal. The user inputs received by the control unit can also include a selected rate at which the tortillas are to be dispensed during the heating session. The outputs provided by the control unit can also include a rate at which tortillas are introduced into the heating sub-system.
An electrical motor-vehicle auxiliary heating device is held in a housing forming oppositely situated air passage areas with formed air passage apertures. A flow resistance element protrudes beyond the outer side of the housing, is manufactured as a component independent of the housing, and is connected to it. The invention also relates to a motor-vehicle air conditioning device with an air conditioning housing which accommodates a motor-vehicle auxiliary heating system and which forms at least one flow channel, which leads to the motor-vehicle auxiliary heating and forms an insertion opening for the motor-vehicle auxiliary heating as well as a boundary wall situated opposite the insertion opening. At least one flow resistance element is provided that is manufactured as a component independent of the housing and the air conditioning housing and that bridges a clearance distance between the housing and the wall(s) of the air conditioning housing.
A method of forming stiffened plate by welding a plurality of stiffener materials and a steel plate, so that closed cross-sectional structures are secured onto a surface of the steel plate. The stiffener materials are joined to the steel plate as a result of edge portions of the stiffener materials which are in contact with the steel plate by being laser welded at a predetermined welding speed as a result of a laser having a predetermined output being irradiated from a predetermined direction thereon from the external side of the closed cross-sectional structures. Accordingly, it is possible to achieve an improvement in the weld quality when welding stiffener materials onto a steel plate, and to achieve an improvement in fatigue strength.
A molded case circuit breaker includes a molded case containing a circuit breaker trip unit, and multiple line connector lugs attached to an end portion of the molded case for connecting the trip unit to power cables from a power source. Rigid support brackets attached to a rigid supporting surface extend along a pair of opposite outer side walls of the molded case adjacent the lugs to resist outward movement of the side walls in the event of a short circuit condition that exerts distorting forces on the lugs and the portions of the molded case adjacent the lugs. The rigid support brackets may be attached to a supporting pan attached to the portion of the molded case adjacent the lugs.
A wiring board has a first resin insulation layer, a first conductive pattern formed on the first resin insulation layer, a second resin insulation layer formed on the first conductive pattern and having an opening portion exposing at least a portion of the first conductive pattern, a second conductive pattern formed on the second resin insulation layer, and a via conductor formed in the opening portion of the second resin insulation layer and electrically connecting the first conductive pattern and the second conductive pattern. The via conductor has a side surface extending between the first conductive pattern and the second conductive pattern and a bent portion where an inclination of the side surface of the via conductor changes in a depth direction of the via conductor.
A wiring substrate includes a substrate body including first and second surfaces on opposite sides and a substrate side surface; a penetration electrode penetrating through the substrate body; a first wiring pattern on the first surface and including a first pad; a second wiring pattern on the second surface and including a second pad; a first insulating resin layer covering the first wiring pattern except for an area corresponding to the first pad and having a first resin side surface; a second insulating resin layer covering the second wiring pattern except for an area corresponding to the second pad and having a second resin side surface that is flush with the first resin side surface; a notch part encompassing at least apart of the substrate body and having a resin material provided therein. The substrate side surface is located more inward than the first and second resin side surfaces.
A wire protective member (10) is provided for covering a wire (11) from an outer side. The wire protective member (10) has a first base (13) includes a first adhesive layer (12) to be bonded to the wire (11) on one surface thereof, a second base (16) to be placed on a surface of the first base (13) opposite to the one including the first adhesive layer (12), and spacers (14) formed between the first and second bases (13, 16). No clearance is formed between the wire (11) and the protective member (10) to achieve a space saving. Further, since it is sufficient to wrap the wire (11) with one member composed of the first adhesive layer (12), the first base (13), the layer partly formed with the spacers (14) and the second base (16), time and effort for a mounting operation and the number of parts can be reduced.
Disclosed is a casing for an electronic wireless handheld device defined by a front panel, a rear panel, and a plurality of side panels connecting the front and rear panels wherein, the device is to be received within the casing such that the front and rear exterior surfaces of the device abut the interior surfaces of the front and rear panels respectively. The casing comprises at least one receptacle wherein, each of the at least one receptacle is adapted to receive therewithin at least one accessory of the device and the like.
A line-jumper apparatus typically includes a first connector, a second connector, and a housing attached to the first connector and the second connector. In a closed position, the housing provides a low-resistance current path and a high-resistance current path between the first connector and the second connector. In an open position, the housing inhibits current from flowing between the first connector and the second connector. The housing is configured so that, when the housing is transitioned from the closed position to the open position, the low-resistance current path is opened before the high-resistance current path. The housing typically includes a safety mechanism that prevents the low-resistance current path from being opened unless the high-resistance current path is closed.
Thin film photovoltaic cells and methods of manufacturing such cells that include one or more diffusion barrier layers configured to provide a relatively smooth growth surface for subsequent deposition of a p-type semiconductor layer. Diffusion barrier layers according to the present teachings may be amorphous, microcrystalline or nanocrystalline layers of materials including molybdenum, conductive oxides, conductive nitrides, conductive carbides, or mixtures thereof. In some cases a diffusion barrier layer may be configured to have surface roughness less than a predetermined threshold value.
Formulations and methods of making solar cells are disclosed. In general, the invention provides a solar cell comprising a contact made from a mixture wherein, prior to firing, the mixture comprises at least one aluminum source, at least one boron source, and about 0.1 to about 10 wt % of a glass component. Within the mixture, the overall content of aluminum is about 50 wt % to about 85 wt % of the mixture, and the overall content of boron is about 0.05 to about 20 wt % of the mixture.
Thin film PV cells and strings of such cells that may be electrically joined with electrical conductors or electroconductive patterns are disclosed. The electrical conductors wrap or fold around the PV cells to form an electrical series connection among those cells. The electrical conductors may be formed or deposited on an electrically insulating sheet, which is then wrapped or folded around those cells. By constructing the electrical conductor and positioning the cells appropriately, an electrical connection is formed between one polarity of a given cell and the opposite polarity of the adjacent cell when the sheet is folded over. One or more dielectric materials may be applied or attached to exposed edges of the cells or conductive traces prior to folding the electrical conductors and/or electrically insulating sheet to prevent shorts or failure points.
Provided are an electronic musical instrument, computer storage device, and method generating tones for held notes. Indication is made of held notes having pitches as held in response to receiving note-on information for the held notes from an input device of an electronic musical instrument while receiving hold information from a hold device of the electronic musical instrument. Note-on information is received for a received note having a pitch while generating the pitches for the held notes. Selection is made of one of the held notes to release according to a first selection criteria in response to determining that the pitch difference of the received note and at least one of the held notes does not exceed the predetermined number of tones or selection is made according to a second selection criteria if the pitch difference exceeds the predetermined number of tones.
A system and method that enables a user to generate and manipulate string-instrument chord grids in a digital audio workstation. The system and method for generating a string-instrument chord grid includes receiving first data input and second data input. The first data input can include a chord root note and/or a position for one or more fingering dots. The second data input can include an instrument type and our tuning for one or more strings. Using the received data input, a processor generates an entered string-instrument chord based and displays the entered string-instrument chord on a grid. The processor can also generate and display the musical name of the entered string-instrument chord.
The present invention provides a tensioning apparatus for a string of a stringed instrument, the apparatus including a supporting body portion for releasable engagement between a string and a surface of the neck of the stringed instrument at a fret on the fret board, thereby to raise the string relative to the fret on the fret board; the apparatus further including a biasing element by which lateral tension may be applied to the string.
Sound boards having an elongate, approximately trapezoid shape, provided on the front face with a central longitudinal profiled string-carrier member and on the reverse side with a central profiled reinforcing member or beam, and with two side profiled members or sound bars, symmetrically disposed with respect to the reinforcing beam are provided. In such sound boards the cross-section of the reinforcing beam has a central portion with an increased height or thickness and two adjacent, symmetrical side portions or wings having a height or thickness which tapers gradually towards the outside through a concave arcuate profile up to a predetermined minimum value.
The present invention provides isolated nucleic acids comprising nucleotide sequences encoding isoprenoid modifying enzymes, as well as recombinant vectors comprising the nucleic acids. The present invention further provides genetically modified host cells comprising a subject nucleic acid or recombinant vector. The present invention further provides a transgenic plant comprising a subject nucleic acid. The present invention further provides methods of producing an isoprenoid compound, the method generally involving culturing a subject genetically modified host cell under conditions that permit synthesis of an isoprenoid compound modifying enzyme encoded by a subject nucleic acid.
The invention relates to the soybean variety designated A1026848. Provided by the invention are the seeds, plants and derivatives of the soybean variety A1026848. Also provided by the invention are tissue cultures of the soybean variety A1026848 and the plants regenerated therefrom. Still further provided by the invention are methods for producing soybean plants by crossing the soybean variety A1026848 with itself or another soybean variety and plants produced by such methods.
The present invention relates to methods and compositions for improving the efficiency of Agrobacterium- and Rhizobium-mediated plant cell transformation by use of additional transformation enhancer sequences, such as overdrive or TSS sequences, operably linked to a T-DNA border sequence on a recombinant construct that comprises T-DNA.
A method of making a transgenic plant by transforming into a host plant a recombinant DNA construct that expresses in the transgenic plant a rice polypeptide and the transgenic plant thus produced.
The invention relates to a method for biogas treatment, wherein the gas originating from a fermentation is separated into a usable biogas stream consisting essentially of methane gas and into an exhaust gas stream containing undesired substances, said exhaust gas stream being thermally or catalytically oxidized. According to the invention, the exhaust gas stream is guided prior to oxidation through closed storage containers and/or fermentation residue containers for the inertization of explosive gas concentrations resulting there.
A method of reclaiming alcohols from purification residue includes hydrolyzing a purification residue with an aqueous medium in the presence of (i) an acid and (ii) an oxidizing agent.
Disclosed is a method of making 2-methoxymethyl-1,4-benzenediamine that includes hydrogenating 1-benzylamino-2-(methoxymethyl)-4-nitrobenzene in the presence of a hydrogenation catalyst.
The invention provides a process for producing xylylenediamine, including supplying a solution of phthalonitrile dissolved in a solvent to a reactor filled with a catalyst and hydrogenating the phthalonitrile to produce xylylenediamine, characterized in that the process includes halting supply of the solution; (2) bringing a washing liquid into contact with the catalyst, the washing liquid having a phthalonitrile content of 3 mass % or less and a xylylenediamine content of 1 mass % or more; and after completion of the contact, resuming supply of the solution, and employing the catalyst continuously in hydrogenation. Through the production process of the invention, the catalyst can be employed continuously for a long period of time, and the catalyst-related cost can be considerably reduced.
A process for oxidizing an alkyl-aromatic compound is described. The process includes oxidizing the alkyl-aromatic compound to produce a first oxidation product; contacting at least a portion of the first oxidation product, a solvent comprising an ionic liquid, a bromine source, a catalyst, and an oxidizing agent to produce a second oxidation product comprising at least one of an aromatic alcohol, an aromatic aldehyde, an aromatic ketone, and an aromatic carboxylic acid.
A method for halogenating, sulfonating, or sulfo-halogenating a feed comprising paraffin, by subjecting a mixture comprising the feed and a reagent selected from the group consisting of sulfonating agents, halogenating agents, and combinations thereof to a shear rate of at least 20,000 s−1 to produce a high-shear treated product; cooling the high shear-treated product by heat exchange with a heat transfer medium, to produce a cooled product; and separating the high shear-treated product into an offgas and a liquid product comprising at least one selected from the group consisting of sulfonated paraffins, halogenated paraffins, and sulfo-halogenated paraffins. A high shear system for the production of halogenated, sulfonated, or sulfo-halogenated paraffin is also provided.
The present invention provides a catalyst for synthesizing an aromatic carbonate, a method of preparing the same, and a method of preparing an aromatic carbonate from dialkyl carbonate using the catalyst. The catalyst has a unit structure consisting of Formulae 1a, 1b or 1c: wherein R1 is C1-C5 alkyl, R2 is substituted or unsubstituted phenyl.
The present invention provides a method of preparing lactide with a high yield from lactate obtained through a fermentation process. In certain embodiments, the invention provides a method of preparing high-purity lactide with a high yield, wherein the method comprises treating lactate with a specific solvent, using a catalyst, and phase-separating the resultant. In accordance with the invention, costs for manufacturing polylactic acid can be considerably reduced.
The present disclosure provides processes for the preparation of a compound of Formula I: which is useful as an antiviral agent. The disclosure also provides compounds that are synthetic intermediates to compounds of formula.
The present application provides a process for the preparation of α-carboxamide pyrrolidine derivatives of formula (I), wherein R1 and R2 are independently hydrogen, C1-6alkyl or C3-6cycloalkylC1-6alkyl; or such R1 and R2, together with the nitrogen to which they are attached, may form an unsubstituted 3-, 4-, 5- or 6-membered saturated ring; X is carbon or nitrogen; n is 0, 1 or 2, wherein when present each R5 is independently selected from the list consisting of C1-3alkyl, halogen, cyano, haloC1-3alkyl, hydroxy, C1-3alkoxy and C1-3haloalkoxy; either R6 or R7 is —O—R8, —OCHR9R8, —NCH2R8 or —(CH2)2R8 wherein the other R6 or R7 is hydrogen or R5; and wherein R8 is a phenyl ring or wherein the phenyl ring is optionally substituted by one or more groups independently selected from the list consisting of C1-3alkyl, halogen, cyano, haloC1-3alkyl, hydroxy, C1-3alkoxy and C1-3haloalkoxy; and R9 is hydrogen or C1-3alkyl.
Substituted fused imidazole derivatives, methods of their preparation, pharmaceutical compositions comprising a substituted fused imidazole derivative, and methods of use in treating inflammation are provided. The substituted fused imidazole derivatives may control the activity or the amount or both the activity and the amount of heme-oxygenase.
Disclosed are compounds, compositions and methods for treating various diseases, syndromes, conditions and disorders, including pain. Such compounds are represented by Formula (I) as follows: wherein Q and Z are defined herein.
A fluoro-substituted deuterated diphenylurea compound, especially 4-(4-(3-(4-chloro-3-(trifluoromethyl)phenyl)ureido)-3-fluorophenoxy)-2-(N-(methyl-d3))picolinamide, preparing method and use for treating or preventing tumor and relative diseases thereof.
A process for producing compound C represented by formula C is disclosed: wherein R′ represents substituent groups as described herein. The process can produce pyripyropene derivatives that have acyloxy groups at the 1- and 11-positions and a hydroxyl group at the 7-position and are useful as insect pest control agents at a high yield.
Heteroarylpiperidine and -piperazine derivatives of the formula (I) in which the symbols A, X, Y, L1, L2, G, Q, p, R1, R2 and R10 are each as defined in the description, and salts, metal complexes and N-oxides of the compounds of the formula (I), and the use thereof for controlling phytopathogenic harmful fungi and processes for preparing compounds of the formula (I).
The invention relates to heteroaryl aryl ureas of the formula IA, wherein the radicals and symbols have the meanings as defined herein, the use of such compounds in the treatment of protein kinase dependent diseases; to pharmaceutical preparations comprising said heteroaryl aryl ureas, to processes for the manufacture of such novel compounds and to methods of treatment comprising the use of such heteroaryl aryl ureas.
The present invention relates to an improved process for the preparation of Tenofovir Disoproxil and its pharmaceutically acceptable salts comprising the steps of: a) esterifying Tenofovir with chloromethyl isopropyl carbonate in presence of a base, phase transfer catalyst and optionally dehydrating agent, in a suitable solvent; b) optionally purifying Tenofovir Disoproxil; and c) converting of Tenofovir Disoproxil into its pharmaceutically acceptable salts. The present invention further relates to a process for the preparation of Tenofovir by reacting 1-(6-amino-purin-9-yl)-propan-2-ol with toluene-4-sulfonic acid diethoxy phosphoryl methyl ester in presence of a base in a non-polar solvent medium followed by hydrolysis.
The instant invention describes methods for producing macrocyclic compounds having antiproliferation activity, and useful in methods of treating disorders such as cancer, tumors and cell proliferation related disorders.
The invention relates a mixture of a urethane-aldehyde resin UA prepared by condensation of an aldehyde A1 and an alkyl urethane U, and of a novolak PA, to a process for the preparation of the said mixture, and a method of use thereof as adhesion promoter in rubber goods.
The present invention relates to an ethylene-alpha olefin copolymer comprising long chain branches (LCB), while having a narrow molecular weight distribution. The ethylene-alpha olefin copolymer can be prepared by a continuous solution polymerization process using an activated catalyst composition containing a Group 4 transition metal compound having a monocyclopentadienyl ligand, to which a quinoline amino group is introduced.
A class of bioinspired, cross linking polymers, created by working catechol functionalities into the backbone of a bulk polymer, is disclosed. Varied cross linking groups may be incorporated into different polymer backbones, and subsequently reacted with an array of reagents. An adhesive composition comprising a copolymer, the copolymer comprising pendant dihydroxyphenyl groups; and a crosslinking agent selected from the group consisting of, for example, oxidants, enzymes, metals, and light. A method of preparing an adhesive composition comprising copolymerizing a first monomer comprising pendant dihydroxy-protected dihydroxyphenyl groups; deprotecting the dihydroxy-protected dihydroxyphenyl groups; crosslinking the dihydroxyphenyl groups with a crosslinking agent.
A method for producing a resist copolymer having a weight-average molecular weight of not less than 3000 and not more than 6000, in which copolymer the contents of an oligomer having a molecular weight of not more than 1000 and a byproduct derived from a polymerization initiator are small, is provided.The method for producing a resist copolymer comprises the step of continuously supplying a solution containing a monomer and a solution containing a polymerization initiator to a heated solvent to carry out a radical polymerization, wherein the variation range of the concentration of the polymerization initiator in polymerization solution is within ±25% of the median value between the maximum concentration and the minimum concentration during specific time; and the variation range of the concentration of unreacted monomer in the polymerization solution is within ±35% of the median value between the maximum concentration and the minimum concentration during specific time.
The present invention relates to a novel post metallocene-type ligand compound, to a metal compound containing the ligand compound, to a catalytic composition containing the metal compound, and to a method for preparing same, as well as to a method for preparing olefin polymers using the catalytic composition. The present invention provides a catalyst for preparing special polyolefin-based polymers having excellent activity.
Single-component compositions are disclosed, which can be cured in two stages, wherein in the first curing stage, compositions pre-cured by means of moisture and having in particular plastic properties are formed, and wherein in the second curing stage, compositions cured by means of heat and having in particular elastic properties are formed. The two-stage compositions are suitable in particular as adhesives and have the great advantage that thanks to said two-stage compositions, an adhesive can be applied to a substrate, said adhesive cures by means of moisture in such a way that it can be handled and stored without problems, and said adhesive can be cured easily in an adhering step by means of heat only when needed.
A polymer blend is provided that includes a polycarbonate polyurethane polymer component having a water contact angle greater than 75 degrees and a polyurethane polymer component having a water contact angle less than 75 degrees. The polycarbonate polyurethane component and the other polyurethane polymer can be immiscible with respect to one another, and thus are phase separated in the polymer blend. The weight percentage of the polycarbonate polyurethane polymer component is greater than the weight percentage of the other polyurethane polymer component in the blend. The polymer blend is well suited for realizing a low friction surface of a variety of medical and non-medical devices.
A mixture which comprises a) from 5 to 95% by weight of a copolymer A which comprises one or more copolymer blocks (B/S)A each composed of from 65 to 95% by weight of vinylaromatic monomers and from 35 to 5% by weight of dienes and of a glass transition temperature TgA in the range from 40° to 90° C., b) from 95 to 5% by weight of a block copolymer B which comprises at least one hard block S composed of from 95 to 100% by weight of vinylaromatic monomers and of from 0 to 5 by weight of dienes, and comprises one or more copolymer blocks (B/S)A each composed of from 65 to 95% by weight of vinylaromatic monomers and of from 35 to 5% by weight of dienes and of a glass transition temperature TgA in the range from 40° to 90° C., and comprises one or more copolymer blocks (B/S)B each composed of from 20 to 60% by weight of vinylaromatic monomers and of from 80 to 40% by weight of dienes and of a glass transition temperature TgB in the range from −70° to 0° C., c) from 0 to 45% by weight of thermoplastic polymers C other than A and B, and d) from 0 to 6% by weight of processing aids D, where the entirety of A to D gives 100% by weight, and its use for the production of shrink films.
The present invention has its object to provide a rubber composition for a tread which can prevent reversion and can also achieve environmental performance (excellent rolling resistance, response to depletion of oil resources, attention to CO2 emission), wet grip performance, dry grip performance, handling stability, and durability (abrasion resistance, crack resistance) in a well-balanced manner. The present invention also aims to provide a pneumatic tire using the rubber composition for the tread thereof. The rubber composition for a tread includes a rubber component containing 35% by mass or more of an epoxidized natural rubber; and a white filler, wherein a total sulfur content is less than 1.75% by mass, and a crosslink density is 7.0×10−5 mol/cm3 or more.
A polycarbonate composition is disclosed comprising a polycarbonate resin, a 3-hydroxychromone dye, and an ultraviolet absorber selected from the group consisting of cyanoacrylates, malonates, and oxanilides. The combination of the 3-hydroxychromone dye and ultraviolet absorber results in a composition with good color retention and strong initial fluorescent emission intensity.
Molded articles formed from compositions comprising thermoplastic starch, thermoplastic polymers, and oils, waxes, or combinations thereof are disclosed, where the oil, wax, or combination is dispersed throughout the thermoplastic polymer.
An adhesive composition comprising elastomeric polymer, epoxy resin, reactive diluent, and filler, is suitable for use within the electronics industry, and in particular for wafer back side coating adhesives. The elastomeric polymer is a mixture of a vinyl elastomer and an epoxy elastomer; the reactive diluent is a combination of two or more diluents, one of which must have carbon to carbon unsaturation, providing cross-linking within the composition after cure; and the filler is a non-conductive filler.
Described is a continuous process for preparing nanodispersions including providing a composition comprising a liquid and a solute; heating the composition to dissolution of the solute to form a solution comprising the solute dissolved in the liquid; directing the heated solution through a continuous tube wherein the continuous tube has a first end for receiving the solution, a continuous flow-through passageway disposed in an ultrasonic heat exchanger, and a second end for discharging a product stream; treating the heated solution as the solution passes through the continuous flow-through passageway disposed in the ultrasonic heat exchanger to form the product stream comprising nanometer size particles in the liquid; optionally, collecting the product stream in a product receiving vessel; and optionally, filtering the product stream.
A polymerisable photoinitiator according to Formula (I): wherein: R1 and R2 are independently selected from the group consisting of hydrogen, a substituted or unsubstituted alkyl group, a substituted or unsubstituted alkenyl group, a substituted or unsubstituted alkynyl group, a substituted or unsubstituted aralkyl group, a substituted or unsubstituted alkaryl group, a substituted or unsubstituted aryl or heteroaryl group, a halogen, an ether group, a thioether group, an aldehyde group, a ketone group, an ester group, an amide group, an amine and a nitro group; R1 and R2 may represent the necessary atoms to form a five to eight membered ring; L represents an n+m-valent linking group comprising 1 to 30 carbon atoms; A represents a radically polymerizable group selected from the group consisting of an acrylate group, a methacrylate group, a styrene group, an acryl amide group, a methacryl amide group, a maleate group, a fumarate group, an itaconate group, a vinyl ether group, an allyl ether group, a vinyl ester group and an allyl ester group; and n and m independently represent an integer from 1 to 5.
The use of at least one diphosphine of formula (I), wherein X is S or O; n is 0 or 1; R1, R2, R3, R4 are independently C1-C10-alkyl, C1-C10-hydroxyalkyl, C1-C10-alkoxy, C1-C10-hydroxyalkoxy, C3-C10-cycloalkyl, C3-C10-cycloalkoxy, C6-C10-aryl, C6-C10-aryloxy, C6-C10-aryl-C1-C4-alkyl, C6-C10-aryl-C1-C4-alkoxy, C6-C10-hydroxy-aryl, C6-C10-hydroxy-aryloxy, C1-C10-thioalkyl, C6-C10-thioaryl or C1-C4-thioalkyl-C6-C10-aryl, NR5R6, COR2, COOR5 or CONR5R6; R5, R6 are H, C1-C10-alkyl, C3-C10-cycloalkyl, C6-C10-aryl or C6-C10-aryl-C1-C4-alkyl; as a flame retardant in a polyurethane material is provided.
A matrix material composed of polymer, preferably of thermoplastic polymer, or coating material. The matrix material includes 0.01 to 50% by weight of an additive for foaming of the matrix material which can be triggered by irradiation with laser light or IR light. The additive includes at least the following constituents: a) at least one absorber material which, embedded or dissolved in the matrix material, absorbs laser light or IR light and brings about local heating in the matrix material at the site of irradiation with laser light or IR light, and b) at least one blowing agent which, when heated due to the irradiation with laser light or IR light to temperatures above 50° C., forms a gas which foams the matrix material by decomposition, chemical conversion or reaction.
The invention is directed to a process for the production of hydrocarbon products from a methane comprising feedstock comprising of the steps of: preparing a feed syngas comprising hydrogen and carbon monoxide having a hydrogen/carbon monoxide molar feed ratio in a syngas manufacturing process and using the feed syngas in a Fischer-Tropsch process using one or more fixed bed catalyst beds as present in one or more syngas conversion reactors thereby obtaining the hydrocarbon product and an residual tail gas. The manufacturing process comprises of two parallel operated syngas manufacturing processes starting from the same gaseous methane comprising feedstock. One syngas manufacturing process is a partial oxidation (POX) process which prepares a syngas having a hydrogen/carbon monoxide [H2/CO] molar ratio below the molar feed ratio and The second syngas manufacturing process is a heat exchange reforming (HER) process, which prepares a syngas having a hydrogen/carbon monoxide [H2/CO] molar ratio above the molar feed ratio.
Methods of enhancing the appearance of a mammal's hair/fur are provided by the administration of an oral nutraceutical or food composition comprising steviol or a steviol precursor, without chromene, for a time sufficient and in an amount effective to enhance the overall appearance of the mammal's hair/fur. The enhancement of the appearance of the mammal's hair/fur includes restoring hair/fur color, lessening hair loss, increasing the thickness of hair, counteracting age-associated hair thinning, and delaying the onset or severity of age-associated hair loss and thinning. A nutraceutical or food which includes steviol or a steviol precursor in an amount sufficient to enhance the overall appearance of a mammal's hair/fur is also provided.
The invention discloses a stable intravenous Propofol oil-in-water emulsion composition having mixed preservatives of low toxicity that is capable of withstanding accidental contamination of bacteria and fungi. The preservative system employed comprising of monoglyceryl ester of lauric acid (Monolaurin) and a member selected from (a) capric acid and/or its soluble alkaline salts or its monoglyceryl ester (Monocaprin); (b) edetate; and (c) capric acid and/or its soluble alkaline salts or its monoglyceryl ester (Monocaprin) and edetate.
The present invention provides a salt of ethylenediamine disuccinic acid comprising at least 1.6 mole of alkaline earth metal per mole of ethylenediamine disuccinic acid. Salts of the invention have been found to be useful in providing compositions comprising hydrogen peroxide having improved stability.
The present invention relates to the use of certain dialkyl fumarates for the preparation of pharmaceutical preparations for use in transplantation medicine or for the therapy of autoimmune diseases and said compositions in the form of micro-tablets or pellets. For this purpose, the dialkyl fumarates may also be used in combination with conventional preparations used in transplantation medicine and immunosuppressive agents, especially cyclosporines.
The present application describes modulators of MCP-1 or CCR-2 of formula (I) or stereoisomers or prodrugs or pharmaceutically acceptable salts thereof, wherein W1, W2, W3, Y, Z, R2, R3, R3′ and R4, are defined in the specification. In addition, methods of treating and preventing inflammatory diseases such as asthma and allergic diseases, as well as autoimmune pathologies such as rheumatoid arthritis and transplant rejection using modulators of formula (I) are disclosed.
The present invention relates to compounds useful as inhibitors of PLK protein kinase of the following formula: or a pharmaceutically acceptable salt thereof. The invention also provides pharmaceutically acceptable compositions comprising said compounds and methods of using the compositions in the treatment of various disease, conditions, or disorders. The invention also provides processes for preparing compounds of the inventions.
The invention relates to novel oxazolidinones their derivatives, pharmaceutically acceptable salts, solvates, and hydrates thereof. This invention also provides compositions comprising a compound of this invention and the use of such compositions in methods of treating diseases and conditions that are beneficially treated by administering cholesterol ester transfer protein inhibitors.
The presently described technology provides compositions comprising aryl carboxylic acids chemically conjugated to hydrocodone (morphinan-6-one, 4,5-alpha-epoxy-3-methoxy-17-methyl) to form novel prodrugs/compositions of hydrocodone, including benzoates and heteroaryl carboxylic acids, which have a decreased potential for abuse of hydrocodone. The present technology also provides methods of treating patients, pharmaceutical kits and methods of synthesizing conjugates of the present technology.
The present invention provides novel pyrimidine amines of formula (I) which are potent inhibitors of spleen tyrosine kinase, and are useful in the treatment and prevention of diseases mediated by said enzyme, such as asthma, COPD and rheumatoid arthritis.
The present invention provides a compound of formula (I): wherein the variants R1, R2, R3, R4, R6, R7 are as defined herein, and wherein said compound is an inhibitor of CETP, and thus can be employed for the treatment of a disorder or disease mediated by CETP or responsive to the inhibition of CETP.
The present invention provides methods and therapeutic agents for lowering or increasing serum serotonin levels in a patient in order to increase or decrease bone mass, respectively. In preferred embodiments, the patient is known to have, or to be at risk for, a low bone mass disease such as osteoporosis and the agents are TPH1 inhibitors or serotonin receptor antagonists.
The present invention relates to novel heterocyclic compounds as Fatty Acid Binding Protein (FABP) inhibitors, pharmaceutical compositions comprising the heterocyclic compounds and the use of the compounds for treating or preventing a cardiovascular disease, a metabolic disorder, obesity or an obesity-related disorder, diabetes, dyslipidemia, a diabetic complication, impaired glucose tolerance or impaired fasting glucose. An illustrative compound of the present invention is shown below:
The present invention relates, in part, to the discovery that a pharmaceutical composition comprising aripiprazole and a carrier administered in a bolus injection resulted in an extended release profile similar to that obtained by the injection of a poly lactide-co-glycolide microsphere formulation containing the active agent. This surprising result suggests that pharmacologically beneficial extended release formulations without the complexities and expense associated with the manufacture microspheres.
There is provided the use of compounds of formula wherein R1, R2, R3 and E have meanings given in the description, for the preparation of a medicament for killing clinically latent microorganisms. There is also provided the use of compounds of formula I for treating microbial infections, as well as certain compounds of formula (I) per se.
The present invention relates to compounds of formula (I) wherein n represents 0, 1, 2, 3, 4 or 5, R represents independent from each other hydroxyl, cyano, nitro, halogen, alkyl, alkoxy alkylcarbonyl, alkoxycarbonyl, alkylamine, dialkylamine, alkylcarbonylamine, alkylcarbamate Y represents one of the following groups: (Ia) in free base or acid addition salt form, to processes for their production, to pharmaceutical compositions comprising them and their use in the manufacture of a medicament for the treatment and/or delay of progression of psychotic and neurodegenerative disorders.
The invention relates to compounds corresponding to formula (I): in which R2 and R3 together form, with the carbon atoms of the phenyl nucleus to which they are attached, a 6-membered nitrogenous heterocycle corresponding to one of formula (A), (B) or (C) below: in which the wavy lines represent the phenyl nucleus to which R2 and R3 are attached. Preparation process and therapeutic use.
The invention relates to compounds of the general formula (I): wherein R, m, n and o are as defined herein. The invention also relates to a method for preparing the same and to the application in therapy.
An oral dosage form comprising a single dose of 25-hydroxy-vitamin D3 sufficient to elevate the serum level in a human to a concentration in the range of 30 ng/ml to 200 ng/ml for at least 7 days and a pharmaceutically suitable oral carrier system, wherein subsequent single doses at least every 7 days are sufficient to sustain the serum level in a human to a concentration in the range of 30 ng/ml to 200 ng/ml at steady-state pharmacokinetics is disclosed. A method of elevating and sustaining the blood level concentration of 25-hydroxy-vitamin D3 in a human in need thereof comprising orally administering or parenterally administering by injection or infusion, at least once every 7 days, a single dose of 25-hydroxy-vitamin D3 sufficient to elevate the serum level in a human to a concentration in the range of 30 ng/ml to 200 ng/ml for at least 7 days, wherein the single doses orally administered at least every 7 days are sufficient to sustain the serum level in a human to a concentration in the range of 30 ng/ml to 200 ng/ml at steady-state pharmacokinetics is disclosed. The human in need thereof may be a human deficient in vitamin D having a serum level concentration of 25-hydroxy-vitamin D3 less than 30 ng/ml.
The invention relates to plasminogen activator-1 (PAI-1) inhibitor compounds and uses thereof in the treatment of any disease or condition associated with elevated PAI-1. The invention includes, but is not limited to, the use of such compounds to modulate lipid metabolism and treat conditions associated with elevated PAI-1, cholesterol, or lipid levels.
Provided is a novel protein phosphatase inhibitor. The protein phosphatase inhibitor contains, as an active ingredient, a silicon compound represented by the following general formula (1) or a salt thereof, wherein R1, R2 and R3 are the same or different and represent a hydrocarbon group having 1 to 12 carbon atoms; X represents an optionally substituted hydrocarbon group having 3 to 36 carbon atoms or an optionally substituted heterocyclic group; and n represents an integer of 0 or 1.
An ophthalmic composition comprising 0.5 ppm to 3 ppm of poly(hexamethylene biguanide), and 0.002 wt. % to 0.03 wt. % of hyaluronic acid. The weight ratio of hyaluronic acid to poly(hexamethylene biguanide) in the composition is from 45:1 to 120:1. The invention is also directed to a method of cleaning, disinfecting or packaging contact lenses with the composition, or to a method of rewetting contact lenses with the composition.
Process for the preparation of trivalent iron complexes with mono-, di- and polysaccharide sugars, consisting of the activation of the sugar by oxidation with nascent bromine generated in situ by reaction between an alkaline or alkaline earth bromine and an alkaline hypochlorite, the complexation of the activated sugar in solution with a ferric salt dissolved in an aqueous solution, the purification of the resulting solution through ultrafiltration and finally the stabilization of the trivalent iron-sugar complex by heating at a temperature between 60° C. and 100° C. for a period between 1 and 4 hours at a pH between 9.0 and 11.0.
The present invention provides a method for treating or preventing fibrosis comprising administering to a patient in need of such treatment or prevention an amount of microRNA-19b effective to treat or prevent said fibrosis. In some embodiments, the invention relates to inhibiting the activation of collagen-producing cells and thereby treating or preventing fibrosis. The methods of the invention also include detection of biomarkers that can be used to diagnose disease and/or evaluate the prognosis of a patient suffering from fibrosis or at risk of developing fibrosis, such as hepatic fibrosis. Such methods may be used to characterize the progression of diseases associated with fibrosis.
Methods and compositions for reducing viral genome amounts in a target cell are provided. In the subject methods, the activity of a miRNA is inhibited in a manner sufficient to reduce the amount of viral genome in the target cell, e.g., by introducing a miRNA inhibitory agent in the target cell. Also provided are pharmaceutical compositions, kits and systems for use in practicing the subject methods. The subject invention finds use in a variety of applications, including the treatment of subjects suffering from a viral mediated disease condition, e.g., an HCV mediated disease condition.
The polynucleotides of the present invention are complementary to the Initiation Sites of microbes. Invading organisms, sensing the pH and nutrient deprivation of a physiologic environment quickly release these nucleotides triggering rapid growth and mutation—attributes to successfully establishing a nidus of infection. They also stimulate neutrophil functions. Accordingly, the nucleotides, compositions and methods of the present invention may be used to enhance, restore or stimulate an immune response or system of an animal, e.g. to prevent an infection caused by a microorganism, ameliorate an infection caused by a microorganism, or kill an invading microorganism that causes infection or re-establish balance to an immune system. In particular, the polynucleotides, compositions and methods of the present invention may be used to treat or prevent bacterial infections and auto-immune diseases in a mammal in need thereof.
The present invention encompasses methods, compositions, and devices for treating an ocular disease, disorder or condition in a mammal. The invention includes polypeptides that possess anti-inflammatory, anti-apoptotic, immune modulatory and anti-tumorigenic properties, and their application in the treatment of eye disease, particularly diseases of the retina. In particular aspects, the invention includes administration of a therapeutic polypeptide such as a stanniocalcin family member protein for the treatment of an eye disease. Also included are fusion proteins and cells stimulated or modified to express the therapeutic polypeptides as set forth herein.
Methods for increasing urine flow are disclosed, comprising administration of an effective amount of GLP-1, an exendin, or an exendin or GLP-1 agonist. Methods for increasing urinary sodium excretion and decreasing urinary potassium concentration are also disclosed. The methods are useful for treating conditions or disorders associated with toxic hypervolemia, such as renal failure, congestive heart failure, nephrotic syndrome, cirrhosis, pulmonary edema, and hypertension. The present invention also relates to methods for inducing an inotropic response comprising administration of an effective amount of GLP-1, an exendin, or an exendin or GLP-1 agonist. These methods are useful for treating conditions or disorders that can be alleviated by an increase in cardiac contractility such as congestive heart failure. Pharmaceutical compositions for use in the methods of the invention are also disclosed.
The present invention relates to fluorocarbon vectors for the delivery of antigens to immunoresponsive target cells. It further relates to fluorocarbon vector-antigen constructs and the use of such vectors associated with antigens as vaccines and immunotherapeutics in animals.
The present invention relates to the preparation of trimethylcyclododecatriene in a continuous or batchwise process by trimerizing isoprene in the presence of a catalyst system and of a solvent. It is possible to isolate the resulting crude trimethylcyclododecatriene by means of distillation. The dimethylcyclooctadiene formed as a by-product may likewise be isolated from the crude product.
The present invention is to process of making a liquid fabric softening composition using shear, turbulence and/or cavitation, but which requires lower operating pressures than conventional shear, turbulence and/or cavitation processes.
The present invention relates to a dishwashing composition comprising abrasive particles and a suspending aid selected from the group consisting of crystalline wax structurants, micro-fibril-cellulose, amido-gellants, di-benzylidene polyol acetal derivatives, and mixtures thereof, and the process and use thereof.
A treatment medium has a particulate natural substrate saturated, suffused and/or coated with hydrous iron oxide. The particulate substrate can be wood based, such as wood chips, bark, sawdust, wood waste or other plant material (such as straw, lucerne, hay, coconut husk or other bulk particulate plant material). The hydrous iron oxide is provided in aqueous suspension form. The substrate may be tumbled in aqueous hydrous iron suspension to achieve saturation/coating. The resulting hydrous iron oxide bearing medium is either placed loose directly into the target treatment site or contained in bags 18 before placing into the target site.
An improved slurry catalyst feed system for heavy oil upgraded is provided. The catalyst feed system comprises a fresh slurry catalyst and a deoiled spent catalyst, with the deoiled spent catalyst being present in an amount of at least 10% the catalyst feed system. The deoiled spent catalyst is a slurry catalyst that has been used in a hydroprocessing operation resulting in than 80% but more than 10% of original catalytic activity, and containing less than 10 wt. % soluble hydrocarbons as unconverted heavy oil feed. The deoiled spent catalyst is slurried in a hydrocarbon medium as dispersed particles prior to being fed to the heavy oil upgrade system.
An ion exchangeable glass that is free of lithium and comprising 0.1-10 mol % P2O5 and at least 5 mol % Al2O3. The presence of P2O5 enables the glass to be ion exchanged more quickly and to a greater depth than comparable glasses that do not contain P2O5.
A system and method for manufacturing a semiconductor device is provided. An embodiment comprises forming a deposited layer using an atomic layer deposition (ALD) process. The ALD process may utilize a first precursor for a first time period, a first purge for a second time period longer than the first time period, a second precursor for a third time period longer than the first time period, and a second purge for a fourth time period longer than the third time period.
A semiconductor processing apparatus includes a reaction chamber, a loading chamber, a movable support, a drive mechanism, and a control system. The reaction chamber includes a baseplate. The baseplate includes an opening. The movable support is configured to hold a workpiece. The drive mechanism is configured to move a workpiece held on the support towards the opening of the baseplate into a processing position. The control system is configured to create a positive pressure gradient between the reaction chamber and the loading chamber while the workpiece support is in motion. Purge gases flow from the reaction chamber into the loading chamber while the workpiece support is in motion. The control system is configured to create a negative pressure gradient between the reaction chamber and the loading chamber while the workpiece is being processed. Purge gases can flow from the loading chamber into the reaction chamber while the workpiece support is in the processing position, unless the reaction chamber is sealed from the loading chamber in the processing position.
A method for manufacturing solder bumps for through vias in a substrate having a first surface and a second surface opposed to each other. The method includes the steps of forming a blind hole extending in the substrate from the first surface for each via and filling each blind hole with a conductive filler; a deepest part of each filler includes a bump portion made of a solder material. The method further includes the step of removing a part of the substrate extending from the second surface to have at least the bump portions protrude from the substrate. The non-protruding part of each filler defines the corresponding via and the bump portion defines the corresponding bump.
A method includes applying, between connection conductors of adjacent substrates, a junction material containing the first metal or alloy component and the second metal or alloy component having a higher melting point than said first metal or alloy component. The method further includes melting the junction material by a heat treatment.
A semiconductor device has a substrate with a contact pad. A first insulation layer is formed over the substrate and contact pad. A first under bump metallization (UBM) is formed over the first insulating layer and is electrically connected to the contact pad. A second insulation layer is formed over the first UBM. A second UBM is formed over the second insulation layer after the second insulation layer is cured. The second UBM is electrically connected to the first UBM. The second insulation layer is between and separates portions of the first and second UBMs. A photoresist layer with an opening over the contact pad is formed over the second UBM. A conductive bump material is deposited within the opening in the photoresist layer. The photoresist layer is removed and the conductive bump material is reflowed to form a spherical bump.
A semiconductor device includes a substrate having an insulating surface; a light-transmitting first electrode provided over the substrate; a light-transmitting second electrode provided over the substrate; a light-transmitting semiconductor layer provided so as to be electrically connected to the first electrode and the second electrode; a first wiring electrically connected to the first electrode; an insulating layer provided so as to cover at least the semiconductor layer; a light-transmitting third electrode provided over the insulating layer in a region overlapping with the semiconductor layer; and a second wiring electrically connected to the third electrode.
A method for fabricating an integrated circuit (IC) includes initial oxidizing of a semiconductor surface of a substrate. The substrate is heated after the initial oxidizing using a plurality of furnace processing steps which each include a peak processing temperature between 800° C. and 1300° C. The furnace processing steps include at least one accelerated processing step having an accelerated ramp portion in a temperature range between 800° C. and 1250° C. providing an accelerated ramp-up rate and/or an |accelerated ramp-down rate| of at least (≧) 5.5° C./min.
A wiring trench is formed in an interlayer insulating film partway in the depth direction of the interlayer insulating film. A via hole is formed extending from the bottom of the wiring trench to the bottom of the interlayer insulating film. A capacitor recess is formed reaching the bottom of the interlayer insulating film. A conductive member is embedded in the wiring trench and via hole. A capacitor is embedded in the capacitor recess, including a lower electrode, a capacitor dielectric film and an upper electrode. The lower electrode is made of the same material as that of the conductive member and disposed along the bottom and side surface of the capacitor recess. A concave portion is formed on an upper surface of the lower electrode, and the capacitor dielectric film covers an inner surface of the concave portion. The upper electrode is embedded in the concave portion.
Semiconductor component or device is provided which includes a current barrier element and for which the impedance may be tuned (i.e. modified, changed, etc.) using a focused heating source.
A semiconductor device having an improved negative bias temperature instability lifetime characteristic is manufactured by forming a first insulating layer on a substrate, performing a first nitridation on the first insulating layer to form a second insulating layer, and sequentially performing a first and second anneal on the second insulating layer to form a third insulating layer, wherein the second anneal is performed at a higher temperature and with a different gas than the first anneal. A second nitridation is performed on the third insulating layer to form a fourth insulating layer, and a sequential third and fourth anneal on the fourth insulating layer forms a fifth insulating layer. The third anneal is performed at a higher temperature than the first anneal, and the fourth anneal is performed at a higher temperature than the second anneal and with a different gas than the third anneal.
A manufacturing method includes forming a fin-shaped silicon layer on a silicon substrate, forming a first insulating film around the fin-shaped silicon layer, and forming a pillar-shaped silicon layer on the fin-shaped silicon layer; forming diffusion layers in an upper portion of the pillar-shaped silicon layer, an upper portion of the fin-shaped silicon layer, and a lower portion of the pillar-shaped silicon layer; forming a gate insulating film, a polysilicon gate electrode, and a polysilicon gate wiring; forming a silicide in an upper portion of the diffusion layer in the upper portion of the fin-shaped silicon layer; depositing an interlayer insulating film, exposing the polysilicon gate electrode and the polysilicon gate wiring, etching the polysilicon gate electrode and the polysilicon gate wiring, and then depositing a metal to form a metal gate electrode and a metal gate wiring; and forming a contact.
According to one embodiment, firstly, an inversion pattern having a periodic pattern in which a first line pattern and a space are inversed and a non-periodic pattern arranged at an interval which is substantially equal to the width of the first line pattern from the end of the periodic pattern is formed above a processing object so as to correspond to the plurality of spaces between a plurality of first line patterns in a first pattern and the space between the first pattern and a second pattern. Next, a sidewall film is formed around the inversion pattern, and the periodic pattern is removed selectively. Thereafter, the processing object is etched using the sidewall pattern formed of the sidewall film and the non-periodic pattern surrounded by the sidewall film as masks.
Methods in accordance with the invention involve patterning and etching very small dimension pillars, such as in formation of a memory array in accordance with the invention. When dimensions of pillars become very small, the photoresist pillars used to pattern them may not have sufficient mechanical strength to survive the photoresist exposure and development process. Using methods according to the present invention, these photoresist pillars are printed and developed larger than their intended final dimension, such that they have increased mechanical strength, then are shrunk to the desired dimension during a preliminary etch performed before the etch of underlying material begins.
An integrated circuit containing a field controlled diode which includes a p-type channel region between an upper gate and a lower n-type depletion gate, a p-type anode in a p-type anode well abutting the channel region, and an n-type cathode in a p-type anode well abutting the channel region opposite from the anode well. An n-type lower gate link connects the lower gate to the surface of the substrate. A surface control element is located at the surface of the channel region between the cathode and the upper gate. A process of forming the integrated circuit containing the field controlled diode is described.
The invention relates to a method for producing silicon semiconductor wafers and components having layer structures of III-V layers for integrating III-V semiconductor components. The method employs SOI silicon semiconductor wafers having varying substrate orientations, and the III-V semiconductor layers are produced in trenches (28, 43, 70) produced by etching within certain regions (38, 39), which are electrically insulated from each other, of the active semiconductor layer (24, 42) by means of a cover layer or cover layers (29) using MOCVD methods.
Disclosed is a method of manufacturing a thin film transistor device that includes the following steps: forming slanted portions 51 in edges of crystalline semiconductor films 13 (13a and 13b); forming a resist film 15 on the crystalline semiconductor film 13a so as to expose the slanted portions 51 and so as to cover the entire crystalline semiconductor film 13b; performing half exposure of the resist film 15 that is formed on the crystalline semiconductor film 13a; injecting a p-type impurity only into the slanted portions 51 of the crystalline semiconductor film 13a; removing the resist film 15 that is formed on the crystalline semiconductor film 13a by ashing; and injecting the p-type impurity into the entire crystalline semiconductor film 13a.
A multi-step density gradient smoothing layout style is disclosed in which a plurality of unit cells are arranged into an array with a feature density. One or more edges of the array is bordered by a first edge sub-array which has a feature density that is less than the feature density of the array. The first edge sub-array is bordered by second edge sub-array which has a feature density that is less than the feature density of the first edge sub-array, and is approaching that of the background circuitry.
A modularized interposer includes a plurality of interposer units that are assembled to provide a complete set of electrical connections between two semiconductor chips. At least some of the plurality of interposer units can be replaced with other interposer units having an alternate configuration to enable selection of different functional parts of semiconductor chips to be connected through the modularized interposer. Bonding structures, connected to conductive metal pads located at peripheries of neighboring interposer units and an overlying or underlying portion of a semiconductor chip, can provide electrical connections between the neighboring interposer units. The interposer units can be provided by forming through-substrate vias (TSV's) in a substrate, forming patterned conductive structures on the substrate, and cutting the substrate into interposers.
Some embodiments include methods of forming semiconductor constructions. Carbon-containing material is formed over oxygen-sensitive material. The carbon-containing material and oxygen-sensitive material together form a structure having a sidewall that extends along both the carbon-containing material and the oxygen-sensitive material. First protective material is formed along the sidewall. The first protective material extends across an interface of the carbon-containing material and the oxygen-sensitive material, and does not extend to a top region of the carbon-containing material. Second protective material is formed across the top of the carbon-containing material, with the second protective material having a common composition to the first protective material. The second protective material is etched to expose an upper surface of the carbon-containing material. Some embodiments include semiconductor constructions, memory arrays and methods of forming memory arrays.
The present invention relates to a solar cell. The solar cell includes a substrate of a first conductive type, an emitter layer of a second conductive type opposite the first conductive type on the substrate, first and second anti-reflection layers that are sequentially positioned on the emitter layer, a first electrode electrically connected to the emitter layer, first to third passivation layers that are sequentially positioned on the substrate, each of the first to third passivation layers including a plurality of exposed portions, and a plurality of second electrodes electrically connected to portions of the substrate exposed by the plurality of exposed portions.
Gold is used as a micromask to roughen a gallium nitride (GaN) surface in an LED device. In one example, a mesh of ITO (Indium Tin Oxide) is formed on a GaN layer. The mesh has holes that extend down to the GaN. A layer of silicon dioxide is deposited so that it covers the GaN at the bottoms of the holes. A layer of gold is formed over the oxide. A thermal treatment causes the gold to ball up into small gold features. These gold features are used as a micromask in a subsequent etching step. Areas of the bottoms of the holes that are not covered by a gold feature are etched. Etching occurs through the oxide and down into the GaN. The roughening process involves no silver, and involves no harsh cleaning solvents or processes that might otherwise have been used were the micromask made of silver.
A light emitting apparatus comprises an electrically insulating base member; a pair of electrically conductive pattern portions formed on an upper surface of the base member; at least one light emitting device that is electrically connected to the pair of electrically conductive pattern portions; and a resin portion that surrounds at least a side surface of the at least one light emitting device and partially covers the pair of electrically conductive pattern portions. Each of the pair of electrically conductive pattern portions extends toward a periphery of the base member from resin-covered parts of the electrically conductive pattern portions. At least the resin-covered parts of each of the electrically conductive pattern portions has at least one elongated through hole extending in a direction in which the electrically conductive pattern portions extend from the resin-covered parts, wherein the resin portion contacts the base member via the through holes.
A method of fabricating an organic electroluminescent device (OELD) according to the present invention has steps of repairing a pixel region by irradiating a laser on a drain contact hole of a passivation layer in a pixel region in need of the repair; and disabling the connection between an organic electroluminescent diode and a drain electrode of a driving thin film transistor (TFT), where the pixel region of the OELD has i) the driving TFT comprising the drain electrode, ii) the passivation layer covering the driving TFT, while comprising the drain contact hole exposing the drain electrode of the driving TFT, and iii) the organic electroluminescent diode connected to the drain electrode of the driving TFT via the drain contact hole.
A method and apparatus for identifying an object having a pattern of plasmon resonant particles (PREs) distributed in or on the object are disclosed. In the method, a field containing the pattern is illuminated, and one or more spectral emission characteristics of the light-scattering particles in the field are detected. From this data, an image of positions and spectral characteristic values in the field is constructed, allowing PREs with a selected spectral signature to be discriminated from other light-scattering entities, to provide information about the field. The image may be compared to a database of reference images to identify or validate the object.
The present invention provides a method for determining the gender of a fetus by assaying the sex hormones, evaluating the overall reducing/oxidizing (redox) activity, and/or evaluating the radical scavenging capacity of the maternal urine or other body fluid. The method can be used to determine fetal gender at any time point during the entire pregnancy. The body fluid may be processed before assaying. Processing may involve aging the body fluid, or purification of various fractions.
A method for engineering and utilizing large DNA vectors to target, via homologous recombination, and modify, in any desirable fashion, endogenous genes and chromosomal loci in eukaryotic cells. These large DNA targeting vectors for eukaryotic cells, termed LTVECs, are derived from fragments of cloned genomic DNA larger than those typically used by other approaches intended to perform homologous targeting in eukaryotic cells. Also provided is a rapid and convenient method of detecting eukaryotic cells in which the LTVEC has correctly targeted and modified the desired endogenous gene(s) or chromosomal locus (loci) as well as the use of these cells to generate organisms bearing the genetic modification.
The invention provides a cationic lipid comprising: (i) one head group, comprising one or more amino acids, in which at least one amino acid has a side chain that comprises a cationic moiety or a cationic precursor; (ii) a linking moiety of formula (5): —(HNR5)2NC(O)R3C(O)— (5), wherein: each R5 is independently an optionally substituted C1-4 alkylene moiety; and R3 is an optionally substituted alkylene or alkenylene moiety; and (iii) two lipophilic moieties, wherein the head group and each of the lipophilic moieties are connected to the linking moiety through amide linkages.
The present invention provides a polynucleotide delivery system including a cationic polymer to which a rabies virus glycoprotein (RVG) peptide is bound, wherein the cationic polymer includes a biodegradable bond, and a method of delivering polynucleotides to a target cell by using the delivery system.
This invention provides a means for modifying surface properties of a cell culture substrate under specific conditions, to thereby regulate regions to which cells are allowed to adhere or are not allowed to adhere, depending on cell type. This invention relates to a method of cell culture comprising steps of: applying a positive potential to a conductive region of a substrate comprising a base material having a conductive region and a non-cell-adhesive membrane coupled thereto with the aid of silane, so as to separate the non-cell-adhesive membrane from the substrate; and culturing cells in a region from which the non-cell-adhesive membrane has been separated.
The present invention provides a reporter gene containing cell line with increased specificity and/or sensitivity for a particular extracellular signal of interest so that it can be used in a gene-reporter assay to accurately determine the presence and/or level of the extracellular signal of interest in the presence of other extracellular signals that are capable of activating the same signal transduction pathway as the extracellular signal of interest or that are capable of activating another signal transduction pathway capable of modulating the transcription of the reporter gene.
Disclosed are vectors, kits and methods useful in the construction of recombinant cells and DNAs via enhanced efficiency homologous recombination. The vectors are targeting vectors that contain a gene-of-interest spliced between two ends that are homologous to a genome target site. The ends of the vector may be protected from exonuclease attack by deploying a cap, such as a hair pin structure. The vector is linked to a nuclear localization signal sequence, and preferably, a bait peptide that binds to RAD51, to facilitate homologous recombination. The vector may be deployed in myriad genetic transformation applications, such as site-directed mutagenesis, gene therapy, and the like.
A target internalized within a cell (and a binding member that specifically binds thereto) can be identified in an efficient manner by segregating (or substantially segregating) genetic material encoding the binding member from genetic material encoding a binding member that binds to a target that is not internalized. This can be achieved by employing a display library of binding members having a genotype/phenotype linkage via a non-fusion protein format, whereby genetic material encoding non-in-ternalized targets can be segregated (or substantially segregated) without lysing the cells. Internalized genetic material subsequently can be isolated and amplified.
A device for controlling temperature in a reaction chamber is disclosed. The device comprises: a bladder assembly comprising a housing dimensioned to hold a reaction chamber disposed within an interior volume of the housing; and a first temperature-control bladder disposed within the housing, the first temperature-control bladder is configured to receive a temperature-control fluid and comprises a flexible, heat conductive surface that comes in contact with at least a portion of an exterior surface of the reaction chamber after receiving the temperature-control fluid. Also disclosed are a bladder thermal cycler, a temperature-control bladder assembly and methods for producing a thermal cycle in a reaction chamber.
A biological growth plate scanner includes a multi-color illumination system that illuminates a biological growth plate with different illumination colors. A monochromatic image capture device captures images of the biological growth plate during illumination of the growth plate with each of the illumination colors. A processor combines the images to form a composite multi-color image, and/or individual components of the composite image, and analyzes the composite image to produce an analytical result such as a colony count or a presence/absence result. The biological growth plate scanner may include both front and back illumination components. The back illumination component may include a diffuser element disposed under the biological growth plate. The diffuser element receives light from one or more laterally disposed illumination sources, and distributes the light to illuminate a back side of the biological growth plate. The illumination sources in the front and back illumination components may take the form of sets of light emitting diodes (LEDs) that can be independently controlled by the processor.
Disclosed are compositions for activating thrombin precursors to thrombin. The compositions provided include polypeptide compositions wherein the pre-pro-sequence comprises a thrombin cleavage site. The compositions provided also include polynucleotides encoding said polypeptides and recombinant systems for expressing said polypeptides. This disclosure also relates to methods for producing said compositions, recovering said compositions, activating said compositions purifying said compositions and producing active thrombin molecules using the active form of said compositions.
Methods and materials related to producing 3-HP as well as other organic compounds are disclosed. Specifically, isolated nucleic acids, polypeptides, host cells, and methods and materials for producing 3-HP and other organic compounds are disclosed.
The present invention relates to a method for producing a fermentation product from a sugar hydrolysate. The method comprises fermenting the sugar hydrolysate in a fermentation system with yeast to produce a fermentation broth comprising a fermentation product; introducing acid and an oxidant, such as chlorine dioxide, to the fermentation system so as to expose microbial contaminants in the fermentation system at one or more stages to chlorine dioxide and a pH of less than 3.0; and recovering the fermentation product. In one example of the invention, a yeast slurry obtained from a yeast recycle step is treated with acid and the oxidant.
Methods and systems for collecting, purifying, and/or extracting ethanol produced during anaerobic metabolism by aquatic plants is provided. The system includes a cell containing water and an aquatic plant, an ethanol extraction assembly in fluid communication with the cell for removing ethanol from the water. Ethanol is released by the aquatic plant by initiating an anaerobic process in the plant such as by regulating the photosynthesis inducing light that reaches the aquatic plant.
A method of producing lactic acid by separating lactic acid produced in a culture solution by microbial fermentation, comprising: a step (A) of filtering the culture solution through a nano-filtration membrane; and a step (B) of distilling a lactic-acid-containing solution produced in step (A) under a pressure of 1 Pa to atmospheric pressure (inclusive) at a temperature of 25 to 200° C. (inclusive) to recover lactic acid.
The present invention relates to isolated polypeptides having xylanase activity and polynucleotides encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods of producing and using the polypeptides.
The present invention relates to isolated polypeptides having cellobiohydrolase activity and polynucleotides encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods of producing and using the polypeptides.
A method for molecular haplotyping of a subject is disclosed. The method comprises: randomly selecting a set of chromosomes in each of a plurality of lyzed diploid cells of the subject, collecting the selected chromosomes from said plurality of cells into a plurality of sample tubes, wherein each sample tube contains chromosomes selected from one or more cells, genotyping genomic DNA in each sample tube, and determining haplotype of the alleles based on allele nucleotide sequence information and corresponding nucleotide signal intensities from genotyping data. Other methods for molecular haplotyping using single cell lysate or single cell microdissection are also disclosed.
A recombinant expression vector comprising: a) the sequence encoding a purine nucleoside phosphorylase (PNPase, E. C. 2.4.2.1), b) the sequence encoding a uridine phosphorylase (UPase, E. C. 2.4.2.3), c) or both; each of the sequences operably linked to one or more control sequences that direct the production of said phosphorylases in a suitable expression host; said sequences originating from the Archaea Thermoprotei class, characterized in that the PNPase is from Sulfolobus solfataricus (SEQ ID NO. 7) and the UPase is from Aeropyrum pernix (SEQ ID NO. 8). In addition, the present invention relates to A transglycosylation method between a sugar-donating nucleoside and an acceptor base in the presence of phosphate ions, characterized in that said method comprises the use of a uridine phosphorylase (UPase) of Aeropyrum pernix (NC_000854.2), a purine nucleoside phosphorylase (PNpase) of Sulfolobus solfataricus (NC_002754.1), or a combination thereof.
The present invention concerns an antibody which specifically binds to an abnormal superoxide dismutase 1 (SOD1), and which neutralizes its pathologic effect when administered to an animal such as a human. The antibody of the invention is a monoclonal antibody produced by hybridoma cell lines deposited with the International Depositary Authority of Canada on Aug. 29, 2006 under accession numbers ADI-290806-01, ADI-290806-02 and ADI-290806-03. The present invention also concerns the use of the antibody of the invention in the treatment, prevention and diagnosis of neurodegenerative diseases such as Amyotrophic lateral sclerosis, Parkinson and Alzheimer in an animal such as a human.
Methods and compositions for natural product optimization are provided. In particular, methods and compositions for selecting bacterial strains (e.g., predatory bacteria such as myxobacteria) which produce a desired compound (e.g., antibiotic, antifungal, or anticancer agent) are provided.
A method for determining the activity of proteases is provided. Fluorogenic substrates from which the fluorogen 7-amino-4-trifluoromethylcoumarin is eliminated proved to be particularly advantageous for the activity measurement. These substrates make it possible for measurement in microtiter plates with a fluorescence reader and thus for the fluorimetric determination of such enzyme activities in blood serum.
The present invention relates to a structure comprising a biological membrane and a porous or perforated substrate, a biological membrane, a substrate, a high throughput screen, methods for production of the structure membrane and substrate, and a method for screening a large number of test compounds in a short period. More particularly it relates to a structure comprising a biological membrane adhered to a porous or perforated substrate, a biological membrane capable of adhering with high resistance seals to a substrate such as perforated glass and the ability to form sheets having predominantly an ion channel or transporter of interest, a high throughput screen for determining the effect of test compounds on ion channel or transporter activity, methods for manufacture of the structure, membrane and substrate, and a method for monitoring ion channel or transporter activity in a membrane.
The present invention relates to the discovery that the T1R receptors assemble to form functional taste receptors. Particularly, it has been discovered that co-expression of T1R1 and T1R3 results in a taste receptor that responds to umami taste stimuli, including monosodium glutamate. Also, it has been discovered that co-expression of the T1R2 and T1R3 receptors results in a taste receptor that responds to sweet taste stimuli including naturally occurring and artificial sweeteners. Finally, the invention relates to the discovery that some compounds, e.g., lactisole, inhibit both the activities of human T1R2/T1R3 and T1R1/T1R3 receptors, and accordingly the sweet and umami taste, suggesting that these receptors may be the only sweet and umami receptors.
The invention comprises a method for the determination of the binding coefficient of a hydrophobic chemical compound comprising: g. Providing an assay plate with a plurality of rows and columns of test vessels; h. Providing the majority of the test vessels in said assay plate with a polymer, wherein in each row the amount of polymer coating per test vessel is increased; i. Filling each test vessel with a solution of binding partner to which the binding coefficient should be assayed, wherein in each column the amount of binding partner is increased; j. Adding the hydrophobic compound and incubate the plate; k. Determining the concentration of said compound in said polymer or in the solution; l. Calculating the protein binding coefficient of the compound.
The invention relates to anti-α2 integrin antibodies and their uses. Humanized antibodies are disclosed that bind to the I domain of α2 integrin and inhibit the interaction of α2β1 integrin with collagen. Also disclosed are therapeutic uses of anti-α2 integrin antibodies in treating α2β1-mediated disorders, including anti-α2 integrin antibodies that bind to α2 integrin without activating platelets.
The present invention provides a composite material including a substrate having an oxide surface, and, a continuous monolayer on the oxide surface, the monolayer including a silicon atom from a trifunctional alkyl/alkenyl/alkynyl silane group that attaches to the oxide surface, an alkyl/alkenyl/alkynyl portion of at least three carbon atoms, a polyalkylene glycol spacer group, and either a reactive site (e.g., a recognition ligand) or a site resistant to non-specific binding (e.g., a methoxy or the like) at the terminus of each modified SAM. The present invention further provides a sensor element, a sensor array and a method of sensing, each employing the composite material. Patterning is also provided together with backfilling to minimize non-specific binding.
The present invention reveals novel methods for producing novel carbohydrate compositions, glycomes, from animal tissues. The tissue substrate materials can be total tissue samples and fractionated tissue parts, or artificial models of tissues such as cultivated cell lines. The invention is further directed to the compositions and compositions produced by the methods according to the invention. The invention further represent methods for analysis of the glycomes, especially mass spectrometric methods.
The present invention relates to methods of detecting the presence of a genetic polymorphism within two or more closely linked, homologous genes, for example α-thalassemia, in a sample using RT-PCR by subjecting the sample to separate amplification reactions using (a) a pair of forward and reverse primers specific for the head region of each of said two or more closely linked, homologous genes and (b) a pair of forward and reverse primers specific for the tail region of each of said two or more closely linked, homologous genes; and detecting and quantitating the amplification products relative to a control product.
A probe for detecting a polymorphism at position −1639 of the VKORC1 gene, the probe comprising an oligonucleotide having a nucleotide sequence having a length of 10 to 50 nucleotides, which nucleotide sequence comprises the nucleotides 80 to 89 of SEQ ID NO:1 or 2 and has a homology to SEQ ID NO:1 or 2 except that the nucleotide corresponding to the nucleotide at position 80 in SEQ ID NO:1 or 2 is cytosine, which nucleotide corresponding to the nucleotide at position 80 is labeled with a fluorescent dye.
This invention relates to methods for detecting and sequencing target nucleic acid sequences, to mass modified nucleic acid probes and arrays of probes useful in these methods, and to kits and systems which contain these probes. Useful methods involve hybridizing the nucleic acids or nucleic acids which represent complementary or homologous sequences of the target to an array of nucleic acid probes. These probes comprise a single-stranded portion, an optional double-stranded portion and a variable sequence within the single-stranded portion. The molecular weights of the hybridized nucleic acids of the set can be determined by mass spectroscopy, and the sequence of the target determined from the molecular weights of the fragments. Probes may be affixed to a solid support such as a hybridization chip to facilitate automated molecular weight analysis and identification of the target sequence.
Human CDK9 genes are identified as modulators of the IGF pathway, and thus are therapeutic targets for disorders associated with defective IGF function. Methods for identifying modulators of IGF, comprising screening for agents that modulate the activity of CDK9 are provided.
The invention relates to methods for the diagnosis of non-alcoholic steatosis (NASH). The method relies on the determination of certain metabolic markers in a biological sample of the patient which are up- or down-regulated in the NASH patients vs. patients with a simple fatty liver (steatosis).
Methods of isolating membrane vesicles from a biological fluid sample are provided. In some embodiments, the methods comprise providing a biological fluid sample comprising membrane vesicles; filtering the biological fluid sample through a filtration module comprising a filter having an average pore diameter of between about 0.01 um and about 0.15 um; and collecting from the filtration module a retentate comprising the membrane vesicles, thereby isolating the membrane vesicles from the biological fluid sample.
The present invention relates to compositions and methods for detecting Mycobacterium genus (Mycobacterium sp.) bacteria (e.g., M. tuberculosis) and M. avium complex (MAC; M. avium, M. scrofulaceum and M. intracellulaire) in a clinical sample or culture. The present invention also relates to differentiating cultures or samples comprising (Mycobacterium sp.) bacteria (e.g., M. tuberculosis) from cultures or samples comprising M. avium complex (MAC; M. avium, M. scrofulaceum and M. intracellulaire).
The present invention provides a method of patterning an electronic or photonic material on a substrate comprising: forming a film of said electronic or photonic material on said substrate; and using an adhesive to selectively remove regions of said electronic or photonic material from said film, thereby leaving on said substrate said patterned electronic or photonic material.
An optical information recording medium 1 is constructed by sequentially layering a reflective layer 11, a protective layer 12, a recording layer 13, a protective layer 14, and a light transmissive protective layer 15 on a substrate 10. As the recording layer 13, a recording layer containing ZnS, SiO2, and Sb as principal components, or preferably, a recording layer expressed by a compositional formula [(ZnS)x(SiO2)1-x]y(SbzX1-z)1-y (where 0
A radiation-sensitive resin composition includes a first polymer, a second polymer and a radiation-sensitive acid generator. The first polymer includes a repeating unit (I) shown by the following general formula (1), a fluorine atom in a molecule of the first polymer. The second a polymer includes an acid-labile group, and is insoluble or scarcely soluble in an alkali. R1 represents a hydrogen atom or the like, each of X1 and R2 represents a single bond or the like, R3 represents a hydrogen atom or the like, and R4 represents an acid-labile group.
A method for producing an antenna structure for an RFID device, a dry toner for use in producing an antenna for an RFID device and a RFID device comprising an antenna structure made of fused toner are disclosed. In a method for producing an antenna structure for an RFID device, a dry toner comprising a polymeric binder and metallic particles is provided. The toner comprises particles having a resistance allowing triboelectric charging or a resistance allowing inductive charging, wherein said metallic particles are nanoparticles having a mean particle size below approximately 500 nm in at least one direction. In the method, a continuous layer of the dry toner is applied to a substrate in a desired shape of an antenna via an electrophotographic printing process, and subsequently the toner is fused to the substrate by heating the toner above its glass transformation temperature. The dry toner for use in producing an antenna for an RFID device comprises toner particles having a resistance allowing triboelectric charging or a resistance allowing inductive charging. The toner particles comprise a polymeric binder and metallic particles, wherein said metallic particles are nanoparticles having a mean particle size below approximately 500 nm in at least one direction.
To provide a toner, containing: a binder resin; a crystalline polyester resin; a colorant; and wax, wherein the toner has a fluidized powder characteristic value of 35% to 45%, and a BET specific surface area of 2.8 m2/g to 4 m2/g, and wherein the toner has an intensity ratio P2850/P828 of 0.10 to 0.20, where P2850 is an intensity of a peak at 2850 cm−1 which is attributed from the wax and the crystalline polyester resin, and P828 is an intensity of a peak at 828 cm−1 which is attributed from the binder resin, as measured by total reflectance infrared spectroscopy.
Disclosed is an LCD panel photolithography process, employed in a lithography system for manufacturing a plurality of LCD panel, comprising steps of: performing photolithography to a glass substrate with a first mask, and the first mask comprises a plurality of sets of alignment marks corresponding to a plurality of following masks thereafter, and a plurality of sets of alignment marks corresponding to the plurality of following masks thereafter are formed on the glass substrate; and employing the plurality of sets of alignment marks on the glass substrate respectively, to perform alignment procedure and photolithography for the plurality of following masks with the plurality of sets of alignment marks on the glass substrate to form patterns; wherein corresponding to the same LCD panel area, the plurality of sets of alignment marks on the glass substrate have different position coordinates respectively.
A flow field plate for fuel cell applications includes a metal with a graphene-containing layer disposed over at least a portion of the metal plate. The graphene-containing layer includes an activated surface which is hydrophilic. Moreover, the flow field plate is included in a fuel cell with a minimal increase in contact resistance. Methods for forming the flow field plates are also provided.
A fuel cell system includes a reforming unit, a carbon monoxide decreasing unit, a fuel cell, a burner unit, a raw gas supply device, and a heating unit. The heating unit is controlled at a start-up operation of the fuel cell system, so as to adjust an amount of a desorbed raw gas desorbed out of components of the raw gas adsorbed to at least one of a reforming catalyst and a carbon monoxide decreasing catalyst such that a ratio of an amount of combustion air to an amount of a raw gas in the burner unit falls within a predetermined range.
Electrolyte suitable for use in a lithium ion cell or battery. According to one embodiment, the electrolyte includes a fluorinated lithium ion salt and a solvent system that solvates lithium ions and that yields a high dielectric constant, a low viscosity and a high flashpoint. In one embodiment, the solvent system includes a mixture of an aprotic lithium ion solvating solvent and an aprotic fluorinated solvent.
Provided is a secondary battery containing polyalkyleneglycol diglycidylether represented by formula I added in a predetermined amount to an electrolyte for the battery. The secondary battery containing the above additive exhibits remarkably improved high-temperature characteristics, prevents deterioration in rate characteristics and cycle characteristics, and considerably reduces thickness swelling of the battery so as to prevent battery leakage, ultimately enhancing safety of the battery.
A negative electrode for a lithium secondary battery includes a negative-electrode active material having a specific surface area of Sx (m2/g) and an average particle size of Lx (μm), a fibrous conductive material having a specific surface area of Sy (m2/g) and an average length of Ly (μm), and a granular conductive material having a specific surface area of Sz (m2/g) and an average particle size of Lz (μm), in which letting the negative-electrode active material content be X, letting the fibrous conductive material content be Y, and letting the granular conductive material content be Z, Log((SyY+SzZ)/SxX×10−1)×Log((LyY+LzZ)/LxX×101) is defined as an electrode parameter, and the electrode parameter satisfies Log((SyY+SzZ)/SxX×10−1)×Log((LyY+LzZ)/LxX×101)≧0.
Disclosed is a binder, which comprises polymer particles obtained by polymerization of: (a) 1˜80 parts by weight of a (meth)acrylic acid ester monomer; (b) 1˜20 parts by weight of an unsaturated carboxylic acid monomer; and (c) 0.001˜40 parts by weight of a vinyl monomer, based on 100 parts by weight of the binder polymer, and which allows electrode active material particles capable of lithium intercalation/deintercalation to be fixed and linked among themselves, and between the particles and a collector. An electrode comprising the binder, and a lithium secondary battery having the electrode are also disclosed. Further, a method for evaluating interrelation between wettability of a binder to an electrolyte and quality of a battery comprising the binder is disclosed.
The present disclosure relates to an electrolyte for a lithium secondary battery, comprising a non-aqueous solvent, a lithium salt and an additive having a perfluoroalkyl group. By including the additive having a specific structure in the electrolyte, the output of the lithium secondary battery can be improved greatly.
A power accumulator (1) has at least three contacts (5 and 7), the contacts (5 and 7) being partially positive contacts (5) and partially negative contacts (7). The contacts (5 and 7) are arranged symmetrically with respect to the external shape of the power accumulator (1), especially with respect to a longitudinal center plane (3) thereof. In this way, the power accumulator (1) can be inserted in any alignment into a device (consumer or charger) without the danger that the power accumulator (1) will be connected with incorrect polarity.
A cooling manifold assembly for use in a battery pack thermal management system is provided. The cooling manifold assembly includes a coolant tube that is interposed between at least a first row of cells and a second row of cells, where the first and second rows of cells are adjacent and preferably offset from one another. A thermal interface layer is attached to the cooling tube, the thermal interface layer including a plurality of pliable fingers that extend away from the cooling tube and are interposed between the cooling tube and the first row of cells, and interposed between the cooling tube and the second row of cells, where the pliable fingers are deflected by, and in thermal contact with, the cells of the first and second rows of cells.
Provided is a surface coated cutting tool in which a hard coating layer exhibits excellent chipping resistance in high-speed intermittent cutting processes. In the surface coated cutting tool having the hard coating layer including a lower layer (Ti compound layer) and an upper layer (Al2O3 layer) formed by vapor-deposition on the surface of the cutting tool body constituted by a WC-based cemented carbide or TiCN-based cermet, the ratio b/a of the number a of crystal grains in the Ti compound layer present in the interface to which the lower layer and the upper layer are adjacent to the number b of crystal grains in the Al2O3 layer is 4≦b/a≦20, and, furthermore, the average grain diameter of crystal grains in the Ti compound layer immediately below the Al2O3 layer is 0.5 μm or less.
An ultrahigh-strength welded joint with superior strength and toughness, and a method for producing the ultrahigh-strength welded joint by means of single-pass welding by using laser hybrid welding, are provided, wherein the welded joint comprising a steel plate having a plate thickness of 4 mm to 12 mm and including weld metal of almost full martensite structure, wherein, in a cross-section of the welded joint in a direction perpendicular to a welding direction, a cross-sectional shape of the weld metal has a width W1 of 2.0 to 7.0 mm at a surface of the steel plate and a width W2 of 0.5 to 2.4 mm at a position where is separated from the surface by three-quarters of the plate thickness, wherein the weld metal comprises, by mass %, C: over 0.09% to 0.24%; Si: 0.2% to 1.0%; Mn: 0.5% to 2.5%; P: 0.02% or less; S: 0.02% or less; Al: 0.004% to 0.08%; Ti: 0.005% to 0.15%; O: 0.005% to 0.05%; and Ni: 1.0% to 9%, and wherein a carbon equivalent (Ceq) is 0.40% to 1.00%, a value Y as defined by equation (([Si]+[Mn])/40+[Al]+[Ti]) is 0.07% to 0.20%.
The present invention provides a dense-coverage, adherent phosphorous-based coating on the native oxide surface of a material. Disclosed phosphorous-based coatings include phosphate and organo-phosphonate coatings. The present invention also provides further derivatization of the phosphorous-based coatings to yield dense surface coverage of chemically reactive coatings and osetoblast adhesion-promoting and proliferation-promoting coatings on the native oxide surface of a titanium material.
An object of the invention is to provide a method for forming a multilayer coating film with excellent smoothness, distinctness of image, and water resistance, by a 3-coat 1-bake coating method, even when preheating after the application of an aqueous first colored coating composition is omitted. The present invention provides a method for forming a multilayer coating film, including (1) applying an aqueous colored coating composition (A) to a substrate to form a colored coating film; (2) applying an effect pigment-containing aqueous coating composition (B) containing a binder component (b1), an effect pigment (b2), and a hydrophobic solvent (b3) in proportions of 15 to 30 parts by mass of effect pigment (b2) and 25 to 60 parts by mass of hydrophobic solvent (b3) relative to 100 parts by mass of the binder component (b1), to the colored coating film, without preheating the colored coating film, to form an effect coating film having a film thickness of 7 to 13 micrometers when cured; (3) applying a clear coating composition (C) to the effect coating film to form a clear coating film; and (4) heating the three coating films formed in steps (1) to (3) to simultaneously cure these three coating films.
Provided is a lithographic printing plate material having an excellent balance between printing durability and ink-absorbing capability. The lithographic printing plate material has an image-receiving layer on a support, wherein the image-receiving layer contains acetoacetyl-modified polyvinyl alcohol as a resin component, and contains at least 0.4 parts by weight of acetylene glycol per 100 parts by weight of the resin component. The image-receiving layer preferably contains 100 to 300 parts by weight of particles having a mean particle size of 7 to 50 nm, per 100 parts by weight of the resin component. In addition, the support is formed using aluminum that has been subjected to anodic oxidation.
[Problem] An instrument display board is provided which does not need troublesome work for preparing plural plate members, can adopt a great variety of designs, can present a stereoscopic feeling and a high-class feeling, brings about unprecedented color tone variation, metallic texture, brilliancy in the light, etc., is very excellent in high-class feeling and design variation, has excellent appearance quality and therefore can enhance merchantability. A process for producing the instrument display board is provided.[Solution means] The instrument display board includes a light-transmitting substrate, at least one partial print layer, a different-color print layer having a color tone different from that of the partial print layer, said partial print layer and said different-color print layer being provided on a back surface of the light-transmitting substrate, and a shield member that is provided at a position on a front surface of the light-transmitting substrate, said position corresponding to a position surrounding a part or the whole of the outer periphery of a print portion of the partial print layer. A portion of the light-transmitting substrate corresponding to the partial print layer is a transparent layer. The instrument display board can present a stereoscopic feeling without using plural plate members, brings about unprecedented color tone variation, metallic texture, brilliancy in the light, etc., is very excellent in high-class feeling and design variation, has excellent appearance quality and therefore can enhance merchantability. The process of the invention can produce the instrument display board.
An antiglare hard coat film is provided in which light transmittance is high without giving antiglare properties more than necessary, a haze value is low, transparency is excellent, image clarity is high, glare of an image is suppressed, whitishness (white blur) of the film is reduced, contrast deterioration is suppressed, and visibility of the display is improved as compared with prior-art antiglare films.This antiglare hard coat film is formed by providing an antiglare hard coat layer containing organic particulates and a resin on a transparent film. When an average value of height in an evaluation region on the surface of the antiglare hard coat film is set to zero (0), a maximum sectional height represented by a difference between a height maximum value in the evaluation region and a height minimum value in the evaluation region is 0.6 μm or less.
An end cap includes a lid portion configured to close an end surface of an edge protector body, an insertion portion provided to the lid portion and configured to be inserted from the end surface of the edge protector body to the side of a bottom portion of a groove with respect to an inner lip portion, and a cantilevered beam-shaped rod portion provided on the lid portion, configured to be inserted from the end surface of the edge protector body between the inner lip portion and a notched groove (an engaged portion), and provided at a distal end side thereof with a projection (an engaging portion) engageable and disengageable with respect to the notched groove.
Coating compositions include (a) an isocyanate functional prepolymer derived from a polyisocyanate and a tricyclodecane-containing polyester polyol; and (b) a blocked amine curing agent.
To obtain a sugar-plum shaped composite particle, a reaction vessel with 300 parts by weight of water placed therein is charged with 30 parts by weight of polymethyl methacraylate resin particles of 2 μm average particle diameter, and ultrasonic waves are applied to the mixture for 1 minute to obtain a particle dispersion liquid. Subsequently, 15 parts by weight of methyltrimethoxysilane is added to the dispersion liquid to obtain methyltrimethoxysilane hydrolyzates in the dispersion liquid. Thereafter, 10 parts by weight of 1 weight % aqueous ammonia is added thereto and agitated. One minute later, the agitation is discontinued, and the mixture is allowed to stand still for 10 hours to effect maturation. The resultant mixture is filtered and dried to obtain sugar-plum-shaped particles provided on their surfaces with polyorganosiloxane projections.
Disclosed is a method for patterning a nanomaterial using solution evaporation. More particularly, the method for patterning a nanomaterial using solution evaporation includes; coating the nanomaterial with a polymer material and uniformly dispersing the coated nanomaterial in a solvent to prepare a solution containing the nanomaterial, and pouring the nanomaterial-containing solution on a substrate, enabling the nanomaterial to be patterned after evaporation of the solvent.
A method of depositing electrically conductive material onto a dielectric substrate is provided. The method includes the steps of providing a dielectric substrate and depositing electrically conductive material onto the dielectric substrate using a cold spray gas dynamic process, wherein the cold spray gas dynamic process accelerates the electrically conductive material to a supersonic velocity.
The present invention relates to a process for the manufacture of an animal feed block according to a target constituent formulation. The process eliminates spoiling of product by inconsistent and fluctuating levels of active ingredient and wet ingredients so as to ensure repeatability from one batch to another.
Natural cheese which comprises a lactic acid bacterium belonging to Lactobacillus gasseri having a disinfection potency against Helicobacter pylori, and a method for producing the natural cheese.
The present invention provides a method and formulation for treating and preventing asteatosis or “dry ear” symptoms and inflammation. The method of the present invention comprises topically applying to the ear canal a semi-viscous diglycerin and butylene glycol polyhydroxy liquid formulation including hydrocortisone, a natural product anti-irritant, a wound healing agent, and an anti-inflammatory agent, stabilized with a cationic surfactant and a nonionic surfactant.
An antiinfective-free formulation for prophylactic treatment of mastitis in dry cows comprises a seal formulation having approximately 65% by weight of bismuth sub-nitrate in a gel based on aluminum stearate. The seal formulation is prepared by adding the bismuth sub-nitrate to the gel base in at least two separate stages.
Disclosed herein are process for preparing cyclic esters comprising unsaturated functional groups. Also disclosed are copolymers prepared from the cyclic esters. The copolymers can be used to form microparticles, polymer micelles, etc., which are useful in drug delivery applications.
A composition comprising a cannabinoid receptor binding agent attached to a particle for the treatment of skin conditions. The particle may be a nanoparticle, such as nanocrystalline cellulose. The particle may further be modified with functional moieties. Drug delivery properties may be modified by coating the particles or using vesicles to deliver the cannabinoid receptor binding agent and particle. A substrate may be used to deliver the composition to the skin.
Disclosed is an oral dosage form comprising (i) an opioid agonist in releasable form and (ii) a sequestered opioid antagonist which is substantially not released when the dosage form is administered intact, such that the ratio of the mean Cmax of the antagonist after single dose oral administration of the dosage form after tampering to the mean Cmax of antagonist after single dose oral administration of an intact dosage form is at least 1.5:1.
A therapeutic method is described in which copper is delivered into the skin as a complex with sodium chlorophyllin. Sodium copper chlorophyllin is encapsulated in suitable lecithin-type liposomes, containing a high concentration of linoleic acid and having diameters in the range 150-350 nanometers. The method provides therapeutic benefits in the treatment of environmentally-induce premature skin aging, excessively oily skin, acne and acne-related skin disorders, acne-rosacea, and also stimulates the natural tanning response of skin to sunlight and other ultraviolet-containing radiation.
The present invention relates to a pressure sensitive adhesive composition comprising a continuous phase and a discontinuous phase wherein a) the continuous phase comprises a water vapor permeable hydrophobic polymer; and b) the discontinuous phase comprises a water soluble salt.
A gum-like device is designed for the controlled and continued delivery of rifaximin, without producing the usually intense red coloration, for the resolution of the infections and the reduction of the inflammation in the oral cavity and in the laryngo-pharyngeal one. The device also protects either the gum or the dental apparatus from acute infections, from the infiltration and the stagnation of the food, and fights chronic infections such as in the periodontal pockets. Moreover, the device can be used to protect the gum from the traumatizing collision that the food exercises during the mastication.
Water-soluble, solid, film-shaped preparations comprising at least one film-forming polymer selected from the group consisting of the fully and partially hydrolyzed polyvinyl alcohols, and at least one water-insoluble, oily liquid which is incorporated into the film-forming polymer and amounts to at least 30 percent by weight, relative to the dry portion of the preparation. Methods for producing the preparations and the use thereof are also provided.
A therapeutic agent carrier for treating a defect in a bone is disclosed and can include a body that can be configured to approximate a portion of the bone. Further, the therapeutic agent carrier can include a plurality of grooves formed along the body. Each groove can correspond to an incremental length of the body. The therapeutic agent carrier can also include a plurality of dosage stamps along the body and each of the plurality of dosage stamps is adjacent to a corresponding to groove.
A highly compression resistant matrix is provided for implantation at or near a target tissue site beneath the skin. The matrix comprises a polymer and a ceramic skeleton. The compression resistance provides retention of a volume that facilitates bone regeneration.
Active compound mixtures comprising ipconazole and at least one further fungicidally active compound are highly suitable for protecting industrial materials against colonization and destruction by microorganisms.
The invention is for a method of potentiating clinoptilolite, the method including the steps of: providing fresh or spent clinoptilolite; exposing the clinoptilolite to a saline solution having a sodium ion content of about 10% to liberate impurities from the clinoptilolite; and drying the washed clinoptilolite fraction to render a potentiated clinoptilolite fraction. Preferably, the clinoptilolite is exposed to the saline solution for a period of about 48 hours. The washed clinoptilolite may be dried by filtered, heated air. This allows an optimal cation exchange capacity of the clinoptilolite to be reached. The clinoptilolite has uses as a medicament for a variety of aliments.
A composition and method for immunizing a mammal infected with Mycobacterium are disclosed. The genes gcpE, pstA, kdpC, papA2, impA, umaA1, fabG2_2, aceAB, mbtH2, lpqP, map0834c, cspB, lipN, and map1634 of M. paratuberculosis and the products that they encode are vaccine targets for Johne's and Crohn's disease. Eighteen M. paratuberculosis-specific genomic islands (MAPs) were identified. Three inverted large genomic fragments in M. paratuberculosis (INV) were also identified. These genomic identifiers represent novel virulence determinants that can be used as targets for vaccines and for developments of drugs against Johne's disease. The methods can be used to deliver an immunizing compound to a mammal, to provide an immune response against Johne's or Crohn's disease in the mammal.
The invention relates to, in part, secreted proteins of bacterial pathogens and methods for their use. More specifically, the invention provides in part several new common secreted proteins for A/E pathogens. In some embodiments of the invention, these polypeptides and nucleic acid molecules encoding these polypeptides, or portions thereof, are useful as vaccines, diagnostics, or drug screening tools for A/E pathogenic infections, or as reagents.
Disclosed is a composition for preventing and treating acetaminophen induced liver injury including the protein extracted from Porphyra yezoensis. The protein(s), separated and purified from hot water extracts of Porphyra yezoensis, having the molecular weight of 14 kDa measured by sodium dodecyl sulfate polyacrylamide gel electrophoresis, has an excellent effect for inhibiting the oxidative injury of liver tissue and cell apoptosis of liver cells induced by acetaminophen.
This disclosure relates to modified Streptococcus pneumonia pneumolysm (PLY) proteins which lack hemolytic activity and can be used as immunogens in an immunogenic composition or vaccine against invasive pneumococcol diseases caused by S. pneumonia. The modified pneumolysm proteins comprise ammo acid substitutions at threonine 65, glycine 293 and cysteine 428 Nucleic acids, polypeptides encoded thereby, compositions containing the same, methods for using such nucleic acids, polypeptides and compositions are also provided.
In accordance with the subject invention, combination therapies can be used to modulate a patient's immune response in order to prevent, delay and/or reverse type 1 diabetes.
The present invention provides an oral vaccine against a bacterial infectious disease (e.g., typhoid fever, cholera, or dysentery). The oral vaccine of the present invention is a capsule formulation in which a transformed microorganism that expresses a flagellin antigen protein or that secretes a flagellin antigen protein out of the cell of the microorganism is encapsulated with an acid-resistant membrane. Examples of the microorganism include intestinal bacteria belonging to the genus Bifidobacterium, the genus Lactobacillus, the genus Lactococcus, and the like. The form of the capsule formulation may be any one of a seamless capsule formulation, a soft capsule formulation, and a hard capsule formulation.
Methods for modeling cancer cell migration, screening drugs for effects on tumor cell migration, and detecting the potential for tumor cell migration relating to the fusion of a bone marrow derived stem cell with a genetically altered cell. Antibodies against ubiquitin are shown to inhibit tumor cell migration.
The present invention is related to the obtaining of modified antibodies by means of DNA recombinant technology from the murine monoclonal antibody P3 (MAb P3), produced by the hybridoma cell line deposited under Budapest Treaty with accession number ECACC 94113026, and from its anti-idiotype murine monoclonal antibody 1E10(MAbai 1E10), produced by the hybridoma cell line with deposit number ECACC 97112901, with the objective of achieving monoclonal antibodies which preserve the biological function of specifically binding the antigen of the original antibodies, but being at the same time less immunogenic. The chimeric antibodies of the invention contain the variable domains of the murine immunoglobulin and the constant regions of the human immunoglobulin; and those humanized, besides containing the constant regions of the human immunoglobulins, are modified in the murine framework regions (FRs), in particular, in those zones that could be in a T cell antigenic site, so that several positions of the FRS are human as well. These antibodies can be used in the diagnosis and therapy of different types of tumors. The present invention is also related to the use of the antibodies for therapeutic and diagnostic purposes.
The invention provides binding molecules, including antibody molecules which selectively bind to a cell surface antigen of a target cell, and wherein the binding molecules, on binding the cell surface antigen, induce apoptosis of the target cell. There is also provided methods of and pharmaceutical compositions for apoptosis induction and uses thereof.
A system for dispensing a foamed aqueous emulsion is provided. The system is a foam-dispensing container and an aqueous emulsion of an oil component with improved foamability. The foamability is improved by including in the emulsion a polyol poly-12-hydroxystearate surfactant as an emulsifier. The aqueous emulsion contains polyol poly-12-hydroxystearate, an oil component, other surfactants and can contain UV protection factors, water and optionally other auxiliaries and additives.
A contrast marker for indicating a presence of a target cell in an environment comprises a fluorophore, an NMP, and a short spacer and a long spacer linking the fluorophore to the NMP. The short spacer holds the fluorophore at a quenching distance from the NMP and the long spacer holds the fluorophore at a fluorescence enhancing distance from the NMP. The short spacer is configured to be cleaved by a molecule characterizing the target cells.
The present invention relates generally to the fields of chemistry and radionuclide imaging. More particularly, it concerns compositions, kits and methods for imaging and therapy involving N4 compounds and derivatives.
Provided is a method for producing hydrogen aimed at storage and transportation, by which hydrogen for storage and transportation that is necessary for smoothly performing an organic chemical hydride method can be industrially produced efficiently at low cost. The method is a method for producing hydrogen aimed at storage and transportation in an organic chemical hydride method, in which: the hydrogenation process of an aromatic compound uses, as a hydrogen source for the reaction of the aromatic compound, a reaction gas is produced by a reforming reaction and adjusted a hydrogen concentration from 30 to 70 vol % by a shift reaction; and a hydrogenated aromatic compound is separated from a reaction mixture obtained in the hydrogenation process, which is followed by purification.
Embodiments and aspects of the present invention relate to an enhanced hexagonal ferrite magnetic material doped with an alkali metal. The material retains substantial magnetic permeability up to frequencies in the GHz range with low losses. The material may be used in high frequency applications in devices such as transformers, inductors, circulators, and absorbers.
A continuous countercurrent flow process for converting FGD gypsum to ammonium sulfate and calcium carbonate including countercurrent flows with internal recycle of liquids to maximize the purity of reaction products while minimizing reaction times, and further include embodiments of the process that provide a yield of both ammonium sulfate and calcium carbonate to be 97 to 100%, and embodiments that provide for processes having a total time of reaction being 8 to 12 minutes, the invention further including processes for removing contaminants from the FGD gypsum employing an acid rinse process and/or a slurry tank reactor process.
The invention provides a method for oxidizing carbon monoxide present in an oxygen-containing gas phase to carbon dioxide which comprises: adsorbing the carbon monoxide onto porous silica; and irradiating the porous silica with ultraviolet ray. In the invention, mesoporous silica or amorphous silica is used as the porous silica. In particular, silica gel that is amorphous silica is preferably used.
It comprises, in addition to a sampling system (3), at the outlet of a vat (1) containing the liquid to be sampled, a selector (4) that establishes switching on an array of similar vats (1), and especially a suction unit (5) that operates by releasing compressed air into a nozzle (28); the airflow direction is controlled by a valve (29) between a direction directed toward the outlet (6), causing the suction of the liquid from the vat (1), and an opposite direction when the valve (29) is closed, feeding the liquid back into the vat (1) and cleaning the pipe (2).
Combustion tube (100,130,150) and method for combusting a sample to form combustion products for analysis. A primary combustion chamber (102) receives and combusts a sample to form first combustion products. A secondary combustion chamber (110) receives and combusts the first combustion products to form second combustion products. The secondary chamber is disposed around the primary chamber and comprises a plurality of—preferably, three—combustion compartments (112-116). Each successive compartment is disposed around the preceding compartment and defines a respective gas flow channel having an inlet opening (108,118,120) and an outlet opening (118,120,122) at opposite ends. Each successive gas flow channel shares its inlet opening with the outlet opening of the preceding channel. The plurality of combustion compartments define a substantially continuous gas flow conduit from the inlet opening of the innermost compartment to the outlet opening of the outermost compartment. Static gas mixers (132,134) may be employed to enhance mixing of the combustion products.
A hydrogen sensor using a hydrogen-absorbing alloy containing an Mg—Ni-based alloy and a Zr—Ti-based alloy includes a substrate (2), a hydrogen reaction layer (3) formed on the substrate (2) and containing the Mg—Ni-based alloy and the Zr—Ti-based alloy, and a first catalyst layer (4) formed on the hydrogen reaction layer (3) and capable of accelerating hydrogenation of the Mg—Ni-based alloy.
The present invention is capable of determining that a reaction region is in an abnormal reaction state precisely with high reproducibility, executing proper analysis processing in accordance with the determined a state of the reaction region, and efficiently analyzing a characteristic of the reaction region. The present invention obtains intensity values of first and second wavelength components by measurement of light emitted from the reaction region with a spectrometer. A relative intensity calculator calculates relative intensity of the first wavelength component relative to the second wavelength component from the intensity values of the first and second wavelength components. The apparatus determines whether or not the calculated relative intensity is a value within a predetermined range. An output portion provides notification that the state of the reaction region is a predetermined state when it is determined that the relative intensity is within the predetermined range.
The present invention is related to the localized/patterned deposition and/or desorption of (bio)molecules using microelectronic structures. Often pre-existing structures needed for proper functioning of the device (e.g. sensors, . . . ) can be used as individually addressable control structures to achieve localized deposition through thermal and/or electrochemical spotting, thereby reducing the need for and simplifying additional processing steps to achieve localized/patterned deposition. If these multi-purpose structures are not available, additional control structures can be implemented, using microelectronic VLSI production technology.
An automatic analyzer is free from limitations on layout of various mechanisms, and thus causing no bottlenecks, for example, in a space-saving design of the automatic analyzer. This invention includes a coaxial planar duplex arrangement of two dilution disks each with annularly disposed dilution cells, and the dilution disks A and B operate independently of each other. Various mechanisms (parent-sample sampling mechanism, diluent delivery mechanism, diluent/sample mixing mechanism, and diluted-sample sampling mechanism) used in a dilution process can each access the two dilution disks. The dilution process for a parent sample, executed on the dilution disks A and B, can be continuously conducted by providing a fixed delay in operational timing between the two dilution disks.
A free radical sterilization system having a chamber defining a region, and a generator for generating free radical reach effluent from a free radical electric generator and/or a vaporizer. A closed loop circulating system without a free-radical destroyer is provided for supplying the mixture of free radicals from the electric generator mixed with the hydrogen peroxide solution in the form of the effluent to the chamber. The free-radical sterilization system is used in sterilizing items in the chamber and, with an open-bottomed wound chamber, in treating wounds on a body.
The present invention is to provide an air cleaning method and device that realize sufficient purification of polluted air, high-efficiency removal of germs or the like from polluted air, and has a relatively simplified structure.
An apparatus for receiving a plurality of mold assemblies having a first mold portion and a second mold portion operably connected together for forming parts. The apparatus includes a mold holding member and a pair of spaced apart support members extending from the mold holding member to a manufacturing floor. A carriage device is cooperable with the mold holding member for engaging and moving the mold assembly. A lifting mechanism is used for moving the carriage device relative the mold holding member to move the mold assembly to be engaged with mold holding member. A turn table adjacent to the mold holding member holds the mold assemblies and is movable relative the mold holding member thereby replacing the mold assemblies. A controller is operably connected to the mold holding member and the turn table thereby moving the turn table relative the mold holding member to interchange the mold assemblies.
A device for generating a hollow plastic profile, in particular a plastic tube, having an air guidance system for interior cooling of the tube, wherein said device allows for a more simple design, improved process properties, and better tube quality. The device according to the invention comprises an extrusion die (100) having a melt channel (114) encompassing the extrusion axis, an extruder that feeds plastic melt to the extrusion die (100), and a suction device for suctioning air through the interior of the profile opposite the direction of extrusion, wherein the extruder feeds the extrusion die (100) centrally and the suction device comprises a central suction tube (140) disposed within the melt channel and partial flow suction channels (144) connected to the central suction tube (140); in the suctioning direction and leading out of the interior of the extrusion die (100).
A material and method for producing mesostructured materials with multiple functionalities that are independently adjustable and collectively optimizable is provided. The method uses a series of discrete synthesis steps under otherwise mutually incompatible conditions, e.g., from acidic, alkaline, and/or non-aqueous solutions, allows different functionalities to be introduced to the materials and optimized. To illustrate the method, cubic mesoporous silica films were prepared from strongly acidic solutions that were separately functionalized under highly alkaline conditions to incorporate hydrophilic aluminosilica moieties and under non-aqueous conditions to introduce perfluorosulfonic-acid surface groups.
A tungsten cathode material to be used for TIG welding, plasma spraying, plasma cutting, electro-discharge machining, discharge lamps, and the like is improved; use of the radioactive element thorium is reduced; and a long life and a high performance are realized. In a tungsten cathode material, oxide particles containing an oxide or oxides of at least one selected from the group consisting of Sm, Nd, Gd, and La in a total amount of 50 vol % or more are dispersed, the oxide particles having an average particle diameter d satisfying the relationship 0
The present invention provides a stabilizer that can stabilize a salt of 10-(carboxymethylaminocarbonyl)-3,7-bis(dimethylamino)phenothiazine or a derivative thereof even under the existence of moisture or under light irradiation. A compound described in at least one of (1) and (2) below is used as the stabilizer of the salt of 10-(carboxymethylaminocarbonyl)-3,7-bis(dimethylamino)phenothiazine or the derivative thereof. (1) a surfactant having an alkyl group with a carbon number of 8 to 16 (2) at least one pigment substance selected from the group consisting of a compound represented by the following formula (I), a compound represented by the following formula (II), and a flavonoid pigment
A blue phase liquid crystal material includes a liquid crystal host, a chiral reagent and a stable polymer. The chiral reagent is R811. The stable polymer is formed by photo-polymerizing a first monomer and a second monomer. The first monomer is 2-ethylhexyl acrylate (2-EHA), and the second monomer is 2-methyl-1,4-bis{4-[3(-acrylate)propoxyl]benzoicacid}phenylester (PTPTP). The blue phase liquid crystal material has a blue phase temperature range widened to an extremely low temperature. A blue phase liquid crystal composition and a method for manufacturing the blue phase liquid crystal material by using the blue phase liquid crystal composition are also provided.
The present invention relates to compositions and processes of using perfluoropolyether to maintain or improve the oil return, lubrication, cooling capacity, or energy efficiency of a refrigeration, air conditioning or heat transfer system.
Nonflammable compositions comprising fluorinated compounds selected from the group consisting of hydrofluoroalkanes, hydrofluoroalkenes, partially or perfluorinated aromatic compounds, hydrofluoroethers, and fluoroketones; 1,2-dichloroethylene, especially trans-1,2-dichloroethylene; and a stabilizer. These non-flammable compositions which preferably contain 1,1,1,3,3-pentafluorobutane, can be used especially as solvents for cleaning and defluxing electronic components and for degreasing metals. The compositions further may comprise a propellant, e.g. 1,1,1,2-tetrafluoroethane. These compositions are especially suitable as flushing agent.
An apparatus of removing coatings of a line-shaped body of the invention includes a non-equilibrium atmospheric pressure plasma source with radicals controlled, having a plasma generating gas, a microwave, a micro gap; a line-shaped body holding portion for holding the line-shaped body within a range of 2 to 3 mm from an electrode to generate a plasma jet; and a moving stage for relatively moving the line-shaped body in the longitudinal direction thereof.
A sensor assembly for a water softening system and includes a first treatment tank having a first valve assembly, a first flow meter and a sensor probe, a second treatment tank having a second valve assembly and a second flow meter and a brine tank independently connected to each of the first treatment tank and the second treatment tank. A controller is configured for communicating with the sensor probe and the first flow meter in the first treatment tank, and the second flow meter in the second treatment tank.
A rapid one-pass liquid filtration system efficiently concentrates biological particles that are suspended in liquid from a dilute feed suspension. A sample concentrate or retentate suspension is retained while eliminating the separated fluid in a separate flow stream. Suspended biological particles include such materials as proteins/toxins, viruses, DNA, and/or bacteria in the size range of approximately 0.001 micron to 20 microns diameter. Concentration of these particles is advantageous for detection of target particles in a dilute suspension, because concentrating them into a small volume makes them easier to detect. Additional concentration stages may be added in “cascade” fashion, in order to concentrate particles below the size cut of each preceding stage remaining in the separated fluid in a concentrated sample suspension. This process can also be used to create a “band-pass” concentration for concentration of a particular target size particle within a narrow range.
A method of purifying impure water contaminated with a filterable impurity and a dissolved impurity, such as seawater, comprising the steps of: providing impure water to a primary microfiltration or ultrafiltration unit to remove the filterable impurity and produce impure filtered water contaminated with a dissolved impurity; providing the impure filtered water contaminated with a dissolved impurity to a reverse osmosis unit to produce a potable water stream and a residual reverse osmosis stream; and treating the residual reverse osmosis stream prior to reuse. The treatment may be in the form of passing through a secondary filter (such as another microfiltration or ultrafiltration membrane or a cartridge filter, and the subsequently treated reverse osmosis reject may be used to backwash the microfiltration or ultrafiltration unit.
The installation comprises three reaction vessels (100, 200, 300) in series, each containing an aqueous phase and a specific bacterial population. The vessels serve in succession to dissolve the liquid feedstock for treatment by enzymatic hydrolysis, then to biodegrade the resulting effluent by biological digestion, and finally to reduce the residual bacterial components by biological action. The vessels are mutually isolated by tangential filters (108, 208, 308) and by centrifugal separators (212, 312) for filtering the biomass from the reaction products. The result is a final liquid effluent (EFF/N) that is essentially non-organic, with the filtered biomass downstream constituting an ultimate organic waste (DU) of reduced volume.
A fitting coupler is provided configured for coupling a planar fluid conduit and a fluidic device. The fluidic device comprises a cavity, a device conduit, and a mouth where the device conduit opens into the cavity. A contact pressure element is configured for sealingly pressing the planar fluid conduit to the mouth, so that a conduit opening of the planar fluid conduit opens into the mouth.
Apparatus for treating run-off water, the apparatus including a mechanical-sorption filter for removing particulate and colloidal material; an ion exchange filter for removing positively charged ions; and, a sorption filter for removing at least other soluble contaminants.
A bottle comprises a cap, a reservoir having an open top closeable by the cap, and a filter holder that houses a filter, the filter holder being coupled to the cap such that a liquid in the reservoir is filtered by the filter as the liquid is being consumed, and the filter is fluidly decoupled from the reservoir when the cap is disengaged from the reservoir. Preferred filters can be constructed out of high reactivity carbon mixture, activated carbon, iodinated resin, combinations thereof, or any other suitable compositions for filtering water or other liquids, and can be molded into any suitable size and shape. Preferred filter holder can have a top portion and a bottom portion that couple together via a snap fitting, mating threads, or any suitable means, which allow access to the filter, and which have numerous vents that allow liquid to freely flow through the filter.
A method of upgrading coal which comprises: pulverizing low-grade coal; mixing the pulverized low-grade coal with an oil to form a slurry; heating the slurry to or above the boiling point of water to vaporize the water contained in the low-grade coal and dehydrate the coal; compressing a vapor mixture of the steam resulting from the slurry heating and that part of the oil which has vaporized simultaneously and thereby elevating the temperature and pressure of the vapor mixture; and supplying the vapor mixture increased in temperature and pressure by the compression and utilizing this vapor mixture as a high-temperature heat source to heat the slurry. In the method, the vapor mixture before being compressed is brought into contact with an oil in a liquid state. This method is a process in which low-grade coal containing water in a large proportion and hence having a low calorific value is dewatered in an oil to thereby upgrade the coal to a high-calorie fuel for thermal power generation, wherein the vapor mixture to be supplied to a compressor can be purified.
A saturated elastomeric mixture is disclosed having a cured or vulcanized elastomer crumb rubber and atmospheric distillations bottoms residue is disclosed.
The present invention is related to a process oil using as a raw material a deasphalted oil obtained by deasphalting a vacuum residual oil of a crude oil and a manufacturing method of the process oil, the process oil having properties of: (a) a polycyclic aromatics (PCA) content of less than 3 mass %; (b) a viscosity (100° C.) of 40 to 70 mm2/s; (c) an aniline point of 85 to 100° C.; (d) a flash point of 250° C. or higher; (e) an aromatic hydrocarbon content of 40 to 55 mass %; and (f) a polar substance content of 10 to 15 mass %. The present invention is also related to a process oil and a manufacturing method of the process oil, the process oil obtained by mixing: an extract obtained by deasphalting and solvent-extracting a vacuum residual oil of a crude oil; and a lubricant base oil having a polycyclic aromatics (PCA) content of less than 3 mass %, and having properties of: (a) a polycyclic aromatics (PCA) content of less than 3 mass %; (i) a viscosity (100° C.) of 30 to 80 mm2/s; (j) an aniline point of 90° C. or lower; (k) a flash point of 240° C. or higher; (l) a benzo(a)pyrene content of 1 mass ppm or less; (m) a specified aromatic compound content of 10 mass ppm or less; and (n) a polar substance content of 10 to 30 mass %.
The presence of oxygen or red blood cells in a sample applied to an electrochemical test strip that makes use of a reduced mediator is corrected for by an additive correction factor that is determined as a function of the temperature of the sample and a measurement that reflects the oxygen carrying capacity of the sample. The measured oxygen carrying capacity can also be used to determine hematocrit and to distinguish between blood samples and control solutions applied to a test strip.
An electrochemical sensor and a method for using an electrochemical sensor are described where the electrochemical sensor comprises a working electrode having thereon one or more redox species that are sensitive to an analyte to be measured and a polymer coating that provides for interaction between the redox species and the analyte.
The present invention relates to an electrode useful in electrochemical nanobiosensors for determining the presence or concentration of analytes in aqueous samples. In particular, the electrode comprises a biocatalyst or other bioreceptor entrapped in a conducting polymeric film deposited on a conducting material and a non-conducting or conducting coating. In particular embodiments, the conducting polymeric layer also comprises metallic nanoparticles. Electrochemical nanobiosensors containing the electrode, methods of making the electrode or sensor and methods of detecting analytes are other aspects of the invention.
Disclosed is a method of treating the surface of an electrically conducting substrate surface wherein a tool comprising an ion-conducting solid material is brought into contact at least in some areas with the substrate surface. The tool conducts the metal ions of the substrate and an electric potential is applied so that an electrical potential gradient is applied between the substrate surface and the tool in such a manner that metal ions are drawn from the substrate surface or deposited onto the substrate surface by means of the tool.
An analysis apparatus is provided with a storage tank, an injection nozzle, a syringe, a collection nozzle, a test sample tank, a microchip having two or more separation channels, detectors, a waste liquid tank, a controller, and a power supply. The collection nozzle collects a specimen which becomes a test sample from a test sample container housing the specimen, and transfers the specimen to the test sample tank. The separation channels separate characteristic components contained in the test sample. The injection nozzle is distanced from the collection nozzle and injects the test sample from the test sample tank into the separation channels. The detectors detect the separated characteristic components in the separation channels.
A deposition method comprises flowing a first gas into a metallization zone maintained at a first pressure. A second gas flows into a reaction zone maintained at a second pressure. The second pressure is less than the first pressure. A rotating drum includes at least one substrate mounted to a surface of the drum. The surface alternately passes through the metallization zone and passes through the reaction zone. A target is sputtered in the metallization zone to create a film on the at least one substrate. The film on the at least one substrate is reacted in the reaction zone.
The device of the invention comprises a support having a surface comprising an attachment zone (Z) capable of being functionalized with a probe (A) capable of binding, according to the pH and reversibly, to a target (B) so as to attach it; a working electrode (WE) and a counterelectrode (CE) for this working electrode, arranged on the support in the vicinity of the attachment zone; and means for applying a given electric current or a given potential to said working electrode so as to cause, when said attachment zone and said electrodes are immersed in an aqueous solution, a local variation in pH in the region of said attachment zone.The method for attaching and/or detaching a target or an object according to the invention uses this device, the attachment and/or the detachment being electrochemically controlled with the working electrode.
A clothing for supporting a wet paper web for dewatering is provided, comprising a dewatering fabric extending in a machine direction and formed only from a woven material to have a single, substantially consistent, permeability. A pair of laterally-spaced strip portions extend along the dewatering fabric in the machine direction, with each being substantially and consistently impermeable to air and forming a substantially and consistently smooth non-water-retaining surface. The strip portions define a permeable web-carrying portion of the dewatering fabric therebetween, wherein the paper web carried thereby extends over the entire width thereof. The permeable web-carrying portion allows air to flow therethrough, exclusively of the impermeable strip portions, such that the wet paper web carried only by the permeable web-carrying portion is dewatered. The width of the permeable web-carrying portion thereby defines the width of the wet paper web dried thereon. Associated systems and methods are also provided.
A water-degradable paper sheet has a basis weight of 80 to 400 g/m2 and is dry-formed from paper fibers bound together by a water-soluble binder including starch, the amount of binder in the sheet being 30 to 70%. Additionally, a tube is formed by a cylinder having a wall that includes at least one dry-formed paper sheet including paper fibers bound together by a water-soluble binder.
The invention relates to a method for increasing the benefit from starch in pulped, preferably repulped cellulosic material at paper or paperboard manufacturing comprising the steps of (a) pulping a cellulosic material containing a starch; (b) treating the cellulosic material containing the starch with one or more biocides, preferably in the thick stock area; and (h) adding an ionic polymer and preferably, an auxiliary ionic polymer to the cellulosic material; wherein the ionic polymer and the optionally added auxiliary ionic polymer preferably have a different average molecular weight and preferably a different ionicity, wherein the ionicity is the molar content of ionic monomer units relative to the total amount of monomer units.
Disclosed are systems, devices and methodologies for separating wafers from carrier plates. In certain wafer processing operations, it is desirable to temporarily mount a wafer on a carrier plate for support and ease of handling. Such a mounting can be achieved by bonding the wafer and the carrier plate with an adhesive. Once such operations are completed, the wafer needs to be separated or unbonded from the carrier plate. Such a separation process can be achieved by applying a mechanical shear force to the wafer-carrier plate assembly. Various devices and methodologies, and related features, are disclosed.
Disclosed are systems, devices and methodologies for debonding wafers from carrier plates. In certain wafer processing operations, it is desirable to temporarily mount a wafer on a carrier plate for support and ease of handling. Such a mounting can be achieved by bonding the wafer and the carrier plate with an adhesive. Once such operations are completed, the wafer needs to be debonded from the carrier plate. Such a debonding process can be achieved by applying a suction force to the wafer-carrier plate assembly. Various debonding systems, devices and methodologies, and related features, are disclosed.
A shower head is provided, in a processing chamber in which a substrate is processed, to face a mounting table for mounting the substrate thereon. The shower head includes: a facing surface that faces the mounting table to supply a gas to the substrate in a form of shower through a plurality of gas injection holes formed on the facing surface; an opposing surface provided opposite to the facing surface; a plurality of gas exhaust holes extending between the facing surface and the opposing surface to perform gas exhaust from the facing surface toward the opposing surface; and a plurality of electrodes provided on the opposing surface, an ion-confining voltage being applied to the electrodes.
A buffer film for multi-chip packaging which does not cause out of alignment during multi-chip packaging and ensures favorable connection reliability has a structure in which a heat-resistant resin layer having a linear expansion coefficient of 80 ppm/° C. or less and a flexible resin layer made of a resin material having a Shore A hardness according to JIS K6253 of 10 to 80 are laminated. A multi-chip module can be produced by aligning a plurality of chip devices on a substrate through an adhesive to perform temporary adhesion, disposing the buffer film for multi-chip packaging between the chip devices and a bonding head so that the heat-resistant resin layer is on a chip device side, and connecting the plurality of chip devices with the substrate by applying heat and pressure to the chip devices toward the substrate with the bonding head.
A method for producing a molded body in which the matrix of a composite material is prevented from penetrating into carbon foam. The method includes: disposing a thermosetting adhesive (3) on a porous body (2), disposing a composite material (4) containing a thermosetting resin as a matrix on the adhesive, curing the adhesive, and liquefying and curing the matrix of the composite material after the adhesive has been cured. In this production method, because the cured adhesive bonds strongly to the porous body before the matrix of the composite material is liquefied, the subsequently liquefied matrix of the composite material can be prevented from penetrating into the interior of the porous body.
Systems and methods for reinforcing an existing pipeline. In some embodiments, the methods include positioning a pipeline wrapping apparatus on the existing pipeline, wherein the pipeline wrapping apparatus comprises a winding head, feeding a strip of material through the winding head, attaching an end of the strip of material to the existing pipeline, and helically wrapping the strip around the existing pipeline by rotating the winding head and axially translating the winding head relative to the existing pipeline.
A system for applying composite fiber to a lay-up tool has a fixed creel for supplying fiber to the fiber placement dispensing head and a fixed arm having a first end attached to the creel and having a second end attached to the dispensing head. The dispensing head is fixed on the end of the arm. A robot having a first and second pivot axis and at least a first wrist supports the lay-up tool. The robot manipulates the tool for application of fiber from the head to the tool. Manipulating the tool instead of the dispensing head allows the path length for the fiber between the creel and head to be fixed in length and orientation during application of fiber to the tool.
A method for producing a plurality of semiconductor wafers includes processing a single crystal. The single crystal is provided in a grown state and has a central longitudinal axis with an orientation that deviates from a sought orientation of a crystal lattice of the semiconductor wafers. A block is sliced from the single crystal along cutting planes perpendicular to a crystallographic axis corresponding to the sought orientation of the crystal lattice of the semiconductor wafers. A lateral surface of the block is ground around the crystallographic axis. A plurality of semiconductor wafers are then sliced from the ground block along cutting planes perpendicular to the crystallographic axis.
In a method for manufacturing ceramic plates, a Pd paste which does not diffuse into ceramic is formed; metal films each having a thickness such that ceramic layers to be formed after firing are not connected to each other in the lamination direction are formed on surfaces of ceramic green sheets using the Pd paste; then, a firing treatment at a firing temperature, which is a high temperature at which no glass component remains on surfaces of the ceramic layers after the firing and which is equal to or lower than a decomposition temperature of a ceramic material forming the ceramic layers, is performed for a laminate; oxygen present at the interfaces between the ceramic layers and the metal layers is removed by immersing a sintered body in n-butyl alcohol so as to separate the ceramic layers and the metal layers.
A method of attaching a first portion and a second portion to each other. An adhesive is exposed to a low temperature in order to obtain a non-tacky adhesive. The non-tacky adhesive is arranged between the two portions. The adhesive is cured. Use of adhesive according to the method.
The present invention provides a high-strength steel plate having excellent resistance to cutting crack, excellent Charpy absorbed energy, excellent DWTT properties, a low yield ratio, and a tensile strength of 900 MPa or more, a method of producing the steel plate, and a high-strength steel pipe using the steel plate. As solving means, a steel plate contains, by % by mass, 0.03 to 0.12% of C, 0.01 to 0.5% of Si, 1.5 to 3% of Mn, 0.01 to 0.08% of Al, 0.01 to 0.08% of Nb, 0.005 to 0.025% of Ti, 0.001 to 0.01% of N, and at least one component of 0.01 to 2% of Cu, 0.01 to 3% of Ni, 0.01 to 1% of Cr, 0.01 to 1% of Mo, and 0.01 to 0.1% of V; wherein the contents of Ca, O, and S satisfy the equation below; the microstructure includes ferrite and a second hard phase, the area fraction of ferrite being 10 to 50%; cementite in the second phase has an average grin size of 0.5 μm or less; and the total amount of Nb and the like contained in carbides thereof present in steel is 10% or less of the total content in steel. 1≦(1−130×[O])×[Ca]/(1.25×[S])≦3 (1)
A cleaning material is applied to a surface of a substrate. The cleaning material includes one or more polymeric materials for entrapping contaminants present on the surface of the substrate. A rinsing fluid is applied to the surface of the substrate at a controlled velocity to effect removal of the cleaning material and contaminants entrapped within the cleaning material from the surface of the substrate. The controlled velocity of the rinsing fluid is set to cause the cleaning material to behave in an elastic manner when impacted by the rinsing fluid, thereby improving contaminant removal from the surface of the substrate.
A delivery device comprises an inlet port and an outlet port. The delivery device comprises an inlet chamber and an outlet chamber, with the outlet chamber being opposedly disposed to the inlet chamber and in fluid communication with the inlet chamber via a conical section. The outlet chamber comprises a labyrinth that is operative to prevent solid particles of a solid precursor compound contained in the delivery device from leaving the delivery device while at the same time permitting vapors of the solid precursor compound to leave the delivery device via the outlet port.
A method for manufacturing a silicon wafer includes a step of annealing a silicon wafer which is sliced from a silicon single crystal ingot, thereby forming a DZ layer in a first surface and in a second surface of the silicon wafer and a step of removing either a portion of the DZ layer in the first surface or a portion of the DZ layer in the second surface.
The present invention provides cement grinding additive compositions and methods which allow a powerful, robust defoamer to be uniformly dispersed throughout a broad concentration range while retaining storage stability even in cases wherein the defoamer is highly diluted. Exemplary cement grinding additive compositions comprise at least one amine cement grinding additive; a tri-iso-butylphosphate defoamer; a biopolymer polysaccharide gum selected from the group comprising Diutan, Whelan, Xanthan, or mixtures thereof; and water in the amount of 0.10 to 95.0 percent based on total weight of composition. Methods for manufacturing cement using the cement grinding additive compositions are also described.
Dried forms of nanocrystalline cellulose (NCC) with controllable redispersibility in water are provided; lightweight and easily transportable dried acid-form nanocrystalline cellulose which can be resuspended for use in a desired application can be produced by maintaining the humidity content of the NCC within a specific, low, range; evaporated acid-form NCC suspensions with moisture contents below this range are non-dispersible and therefore can be subsequently fixed in permanently dried form; the second form is produced by exchanging the proton of the acid-form NCC for neutral monovalent counterions and freeze-drying the NCC to give a solid product which rapidly disperses when placed in water; properties similar to those of the original suspension are also obtained with a brief sonication treatment.
An ink set is provided and includes at least a yellow ink composition, a magenta ink composition, and a cyan ink composition, wherein the yellow ink composition contains as a colorant at least one selected from the group consisting of a compound represented by formula (Y-I) and a salt thereof. where R4 represents a monovalent group; R5 represents —OR6 or —NHR7; each of R6 and R7 represents a hydrogen atom or a monovalent group; X3 represents a divalent linking group; n3 represents 0 or 1; Ar3 represents a divalent heterocyclic group; and Ar4 represents an alkyl group, an aryl group, or a monovalent triazine ring group.
A gas separation membrane comprises aromatic polyimide polymers that comprise a plurality of repeating units of formula (I) wherein X1 and Ar are herein defined.
Vents for containers include a perforated substrate portion (20) of polymer material over which is thermally bonded a gas permeable membrane (30). The thermal bond (31) is direct and adhesive-free so that there is no adhesive available for chemical attachment by materials within the containers (58) and no opportunity for an adhesive to interfere with or block perforations through the substrate.
One example embodiment includes a system for removing cooling liquid from a mist. The system includes an intake, where the intake is configured to receive the cooling mist. The system also includes a mist filter, where the mist filter is configured to remove cooling liquid from the mist. The system further includes an exhaust, where the exhaust is configured to output the demisted air.
A method for cyclically preparing titanium sponge and coproducing sodium cryolite using sodium fluotitanate as an intermediate material, which includes the following steps: A) adding hydrofluoric acid to titaniferous iron concentrate to enable a reaction to form fluotitanic acid; B) adding sodium carbonate and sodium hydroxide to the fluotitanic acid to enable a reaction to form the sodium fluotitanate; C) putting the sodium fluotitanate into a reactor, adding aluminum to react with the sodium fluotitanate to form the titanium sponge and sodium cryolite; D) extracting the sodium cryolite and sending it to a rotary reaction kettle together with concentrated sulphuric acid to enable a reaction to form hydrogen fluoride gas and sodium sulphate, aluminum sodium sulphate; collecting the hydrogen fluoride gas and dissolving it into water to obtain a hydrofluoric acid solution; E) recycling the obtained hydrofluoric acid to Step A to leach the titaniferous iron concentrate.
The present invention provides a method for forming compositions having a plurality of ultra-fine metallic particles, and the metallic composition produced therewith. Also provided is a substrate coated with the plurality of ultra-fine metallic particles obtained in accordance with the method of the present invention.
Provided are a method of producing mixed powder comprising noble metal powder and oxide powder, wherein powder of ammonium chloride salt of noble metal and oxide powder are mixed, the mixed powder is subsequently roasted, and ammonium chloride is desorbed by the roasting process in order to obtain mixed powder comprising noble metal powder and oxide powder, and mixed powder comprising noble metal powder and oxide powder, wherein chlorine is less than 1000 ppm, nitrogen is less than 1000 ppm, 90% or more of the grain size of the noble metal powder is 20 μm or less, and 90% or more of the grain size of the oxide powder is 12 μm or less. Redundant processes in the production of noble metal powder are eliminated, and processes are omitted so that the inclusion of chlorine contained in the royal water and nitrogen responsible for hydrazine reduction reaction is eliminated as much as possible. Consequently, the present invention aims to omit the drying process at a high temperature and thereby prevent grain growth and aggregation, and further eliminate the pulverization and classification processes in order to considerably reduce the production cost.
The present invention is directed to peat processing and includes the usage of peat as the organic raw material. The peat is processed through preliminary granulation with further curing of the derived granules in closed tanks for cooling. The cooled granules are subjected to re-granulation. Then the hot granules derived from re-granulation emerge into an aqueous solution. The derived mixture is stirred until it turns into a homogeneous viscous fluid paste. The paste is supplemented with alkali until the pH reaches the value of 10-10.5. The final product results after cooling of the paste to ambient air temperature.
A filter cartridge for use in separating a hydrophobic liquid aerosol phase from a gas stream, as a crankcase ventilation filter for example, is described. The cartridge includes a media pack comprising filtration media surrounding an open interior and a first end piece. Various structure included on the first end piece is described. An example is a D-shaped projection. Also described is an assembly including the filter cartridge, specific features of a housing component of the assembly. Methods of assembly and use are also described.
The disclosed exhaust treatment device for a diesel engine can prevent heat damage to a DPF when regenerating said DPF. If a selection device (7), which selects whether to allow or prohibit an automatic DPF regeneration process, is set to prohibit the automatic DPF regeneration process, a DPF regeneration control device (4) is made able to start a process to cancel execution of the automatic DPF regeneration process. If the selection device (7) is set to allow the automatic DPF regeneration process, the DPF regeneration control device (4) retracts the cancellation of the automatic DPF regeneration process, allowing execution of the previously-cancelled automatic DPF regeneration process to begin.
A process for producing biodiesel from natural oils and/or fats, a low molecular weight C1-C6 alcohol and catalyst is described. The process preferably uses vegetable oils and is specifically configured for producing biodiesel from castor oil.
The invention is to articles of extracellular matrix. The articles comprise one or more sheets of mammalian extracellular matrix laminated together. A single sheet can be folded over and laminated on 3 sides. Two or more sheets can be laminated to each other at their edges. The sheets can further encase a composition comprising a cell or cells, such as for example, a stem cell. A single sheet can be folded over to encase a composition, or rolled to encase a composition with lamination at either end of the roll, for example. The invention also includes methods of using these articles to regenerate tissue at tissue defects, or heal wounds in damaged tissue.
A method for repairing a defect in the annulus of an intervertebral disc uses a port through a vertebra adjacent the disc for passage of a rivet insertion tool to place a first part of a two-part annulus repair rivet against an internal surface of the annulus adjacent the defect. A separate rivet insertion tool places a second part of the annulus repair rivet on an external surface of the annulus adjacent the defect. The first and second parts are secured together, repairing the defect.
An implant for orthopedic applications includes a quantity of flexible, elongated elements at least some of which possess connective tissue-healing activity, the elongated elements being arranged in substantially common alignment along their longitudinal axis.
An intraocular lens comprises an optic and at least two haptics. Each haptic is offset in an anterior direction from a central optic plane of the optic. The offset allows for predictable posterior vaulting upon implantation.
A catheter device having a shaft that extends from a proximal end to a distal end to carry on its distal end a self-expanding implant for intraluminal advance on a guidewire and delivery of the implant to an implant site by proximal withdrawal of a sheath that lies radially outside the implant in the catheter, the catheter including a first shaft element to pull the sheath proximally and a second shaft element to push the implant distally to prevent the implant moving proximally with the sheath when the sheath is pulled proximally, wherein the second shaft element carries a stopper for abutting the implant, the stopper comprising proximal and distal portions having different radiopacities.
A modular dynamic pedicle screw system including anchoring device having a threaded shank for anchoring within a vertebra, an intermediate element and a head portion configured to receive and secure a rigid or non-rigid stabilization rod. The threaded shank, the intermediate element and the head portion of the anchoring device are cannulated to permit percutaneous implantation of the device. The intermediate portion is designed to be removable from the threaded shank portion subsequent to implantation of the anchoring device to enable substitution of another intermediate element having different dynamic characteristics. The dynamic stabilization system includes an adjustable torque limiting device that is interchangeable between a tap device and a screw driver. The torque device provides information relative to the patient's bone quality inter-operatively in order to determine the appropriate modulus of elasticity for the dynamic pedicle screw.
A closing assembly for a clamping device having first and second jaw members includes a closing mechanism connected between the first and second jaw members, the jaws extending distally from the closing mechanism; and a member for applying a separating force to the first and second jaw members proximally of the closing mechanism, whereby the first and second jaw members can be maintained substantially parallel during closing. The clamp has a very strong clamping force.
A surgical tool system. Various embodiments of the surgical tool system may comprise surgical instrument that has a handle assembly that operably supports a drive system therein for generating drive motions upon actuation of a movable handle portion operably coupled to the handle assembly. An elongated body protrudes from the handle assembly and operably supports a control rod therein that interfaces with the drive system. The surgical tool system further includes at least two surgical tools selected from the group of surgical tools consisting of: manipulators, nippers, scissors, endocutters, tissue thickness measurement devices, staple appliers, clip appliers, syringes for applying glue, sealant, drugs or medicaments and cauterization devices wherein each of the surgical tool within the group of surgical tools at least has a housing that is removably couplable to the elongated body and a drive assembly that is removably couplable to the control rod for receiving the drive motions therefrom.
A medical implant for occluding a blood vessel. The medical implant comprises a cup shaped elastic blood impermeable membrane sized and shaped for substantially occluding a lumen of a blood vessel, at least one scaffolding element mounted, sized and shaped for being attached at least one blood clot forming in front of the elastic blood impermeable membrane, and at least one anchoring element having a tip directed outward from the center of the cup shaped elastic blood impermeable membrane.
A precision depth guided instrument, such as a Jamshidi needle, is provided for use in various surgeries related to the vertebrae. The instrument includes an outer cannula, an inner cannula and a stylet. After the cortical bone of a vertebra is penetrated by the outer cannula of the instrument, the depth of penetration of the inner cannula is adjusted by rotation of a stop mounted to the outer cannula. The inner cannula is then moved further into the vertebrae, and a stop mounted on the outer cannula controls the depth of penetration of the inner cannula. The correct depth of penetration is determined by radiography prior to the procedure.
The invention provides a rotational atherectomy device having, in various embodiments, a flexible, elongated, rotatable drive shaft with at least one flexible or inflexible eccentric enlarged abrading and cutting head attached thereto which comprises an abrasive surface. When placed against stenotic tissue and rotated at high speed, the eccentric nature of the abrading and cutting head moves along an orbital path, opening the lesion to a diameter larger than the resting diameter of the enlarged abrading and cutting head. Preferably the abrading and cutting head has a center of mass spaced radially from the rotational axis of the drive shaft, facilitating the ability of the device to travel along an orbital path. The abrading and cutting head comprises proximal and/or distal radiused surfaces that facilitate cutting difficult stenosis material while minimizing trauma to the vessel.
An implantable device system for controlling the dimensions of internal anatomic passages corrects physiologic dysfunctions resulting from a structural lumen which is either too large or too small. Implantable devices are disclosed which employ various mechanisms for adjusting and maintaining the size of an orifice to which they are attached. Systems permit the implants to be implanted using minimally invasive procedures and permit final adjustments to the dimensions of the implants after the resumption of normal flow of anatomic fluids in situ.
A method of fixing a suture to tissue of a patient includes placing an introducer onto a finger, the introducer including a zip line trailing from a proximal end of the introducer. The method additionally includes identifying a landmark with the finger, guiding a delivery device along the zip line toward the introducer, where the delivery device maintaining an anchor attached to a suture line, and ejecting the anchor from the delivery device and into the tissue of the patient.
A suture loading assembly for threading suture material through a device comprises a body, an attaching member extending from the body for attaching the body to the device, and a flexible loop extending from a distal end of the body and threadable through a ferrule in the distal end of the device.
An improved system for mammography analysis and methods of using the same. In one aspect, a clip comprises a first portion and at least one additional second portion connected to the first portion, the first and second portions adapted for elastic deformation for engaging tissue. In anther aspect, an improved actuator for performing a breast biopsy is used to deploy a clip. In yet another aspect of the invention, there is contemplated a system for marking an evacuated breast cyst.
A modular impactor head includes a load transfer member, a base, and a locking assembly. The base defines a space sized and configured to receive the load transfer member therein and to constrain movement of the load transfer member relative to the base in a plurality of directions. The locking assembly is sized and configured to constrain movement of the load transfer member with respect to the base in at least one direction such that the load transfer member is fixed to the base.
Robotic surgical tools, systems, and methods for preparing for and performing robotic surgery include a memory mounted on the tool. The memory can perform a number of functions when the tool is loaded on the tool manipulator: first, the memory can provide a signal verifying that the tool is compatible with that particular robotic system. Secondly, the tool memory may identify the tool-type to the robotic system so that the robotic system can reconfigure its programming. Thirdly, the memory of the tool may indicate tool-specific information, including measured calibration offsets indicating misalignment of the tool drive system, tool life data, or the like. This information may be stored in a read only memory (ROM), or in a nonvolatile memory which can be written to only a single time. The invention further provides improved engagement structures for coupling robotic surgical tools with manipulator structures.
The invention provides systems and methods for sternum repair. A sternum repair device may include a central body, which may include a plurality of male and female components, such that a suture extends from a male component and is received by the female component. The suture may wrap around the sternum and the device may be tightened to keep the separate sternum pieces together.
Systems and methods deploy an electrode from a catheter assembly. The systems and methods provide a catheter handle having a trigger lever adapted to carry an actuator rod. The actuator rod is adapted to cause movement of the electrode between a retracted position and an extended position. A pinion is carried by the trigger lever for engagement with a rack carried by the actuator rod. Compression of the trigger lever moves the rack along the actuator rod between a first position corresponding to the electrodes being in the retracted position and a second position corresponding to either the primed electrode firing position or the electrodes being in an extended position.
According to some embodiments, a method of treating a subject having diabetes or symptoms associated with diabetes is provided. The method includes delivering a neuromodulation catheter within a vessel (e.g., hepatic artery) having surrounding nerves that innervate the liver (e.g., sympathetic nerves of the hepatic plexus). The method may also include modulating (e.g., disrupting, ablating, stimulating) the nerves by mechanical compression, energy delivery, or fluid delivery.
A device used for applying an antiseptic preparation to a surgical site of a patient prior to surgery outside of an operating theater. A loose-fitting bag is provided which encloses the surgical site by securing the open end(s) to the patient by closing means. A high friction scrub surface is provided in the bag. A method and apparatus are also provided for releasing antiseptic into the interior of the bag. The method provides that the surgical site can be scrubbed within the bag so as to properly prepare the skin for surgery. A temperature indicator for the antiseptic preparation is also provided.
The present invention is to provide a gas mist mask device which is compact and economical, and enables to take a mist bath for the face or the eyes by using the physiological actions of oxygen or carbon dioxide. The gas mist mask device comprises a gas supply means 110 of supplying carbon or carbon dioxide, otherwise the mixed gas (called briefly as “gas” hereafter) of oxygen and carbon dioxide, a gas mist generating means 120 connected to the gas supply means for storing a liquid inside thereof and generating a mist (called as “gas mist” hereafter) prepared by pulverizing and dissolving the stored liquid and the gas, and a mask member having a mask main frame 131 with a first sheet passing the gas mist and a second sheet not passing, and holding parts 138 of securing the mask main frame 131 in such a manner that the first sheet is fronted to the eyes or the face of the human living organism, and this gas mist generating means supplies the gas mist between the first sheet and the second sheet, thereby contacting the gas mist to the eyes or the face of the human living organism.
A self-priming IV set valve includes a connector including a valve element that is positioned inside of the connector, and a cap that is removably connected to the connector. When the cap is mounted to the connector a passageway is formed in the connector such that air and liquid are permitted to pass through the connector and into the cap whereupon a hydrophobic filter of the cap prevents the passage of liquid there through while the hydrophobic filter permits the passage of air out of the cap and into the atmosphere. When the cap is not mounted to the connector, the valve element of the connector is configured to open under pressure and close when pressure ceases. Also disclosed is a method of priming the IV set, a cap assembly for a self-priming IV set valve, and a connector for a self-priming IV set valve.
An injection port system comprises an injection port and an applier. The port comprises a body and a plurality of fasteners. The fasteners are integral with the body and are movable from a non-deployed position to a deployed position. The applier comprises a port engagement portion and an actuator. The port engagement portion is configured to selectively engage the port body to selectively retain the port relative to the applier. The actuator is operable to move the fasteners to the deployed position. The applier is also configured to disengage the port engagement portion from the port body to release the port from the applier when the actuator moves the fasteners to the deployed position. The actuator may release the port from the applier by moving a resilient member away from the port body as the actuator also moves the fasteners from the non-deployed position to the deployed position.
A filter and a method treat blood borne carcinomas by inducing apoptosis in carcinoma cells. The filter includes comprises a stent having an interior wall defining a channel containing a packing material and at least one antineoplastic agent. The method includes placing a patient's blood in apposition of the antineoplastic agent by pumping the blood through the stent. The blood remains in apposition to the antineoplastic agent for a sufficient time period to induce an apoptotic cascade.
A support dressing comprises a conformable material that is capable of conforming to a body part when secured thereto; an adhesive for releasably securing the dressing to said body part; and at least one resilient component that has greater stiffness than the flexible material. It is particularly useful in preventing or reducing undesired torsion, especially of the lower back.
A moving body attitude angle processing apparatus capable of reducing cumulative errors in continuously measuring the attitude angle of a moving body is provided. The moving body attitude angle processing apparatus estimates the attitude angle of a moving body in accordance with outputs from an acceleration sensor, a magnetic sensor, and a gyro sensor that are mounted to the moving body, and outputs the attitude angle thus estimated. The moving body attitude angle processing apparatus includes: a gyro sensor that outputs an angular velocity vector; an acceleration sensor that outputs an acceleration vector; a magnetic sensor that outputs a magnetic field vector; a movement state determining device that determines a movement state of a moving body in accordance with an output from the acceleration sensor; and a gyro-sensor zero-point output estimating device that, when the movement state determining device determines the movement state to have been detected as a stationary state of the moving body, carries out a process of estimating a zero-point output of the gyro sensor in accordance with the output from the acceleration sensor, an output from the magnetic sensor, and an output from the gyro sensor.
A guidewire includes a core shaft, and a coiled body wound around the outer circumferential surface of the core shaft. A bulged portion is provided at the tip portion of the core shaft. The front end of the coiled body is bonded to the front end of the core shaft with a bonding portion. The bonding portion is provided to enclose the bulged portion provided at the tip portion of the core shaft.
Pulse waves of a subject are detected in time sequence. Amplitude of the pulse waves is detected, and an interval between two pulse waves adjacent along a time axis is detected. A first change ratio of the interval along the time axis, and a second change ratio of the amplitude divided by the interval along the time axis are calculated respectively. By comparing the first change ratio and the second change ratio with a first threshold and a second threshold respectively, it is decided whether the pulse waves of the subject are irregular.
An ultrasound diagnostic apparatus includes a plurality ultrasound probes, an apparatus body for producing an ultrasound image based on the reception data obtained by one of the ultrasound probes, a connection selector for selectively switching a connection between the ultrasound probes and the apparatus body, an interruption detector for detecting interruption of ultrasound examination, and a controller for causing the apparatus body to display a selection screen for selecting one of the ultrasound probes to be subsequently used when the interruption detector detects interruption of ultrasound examination, wherein when an operator selects one of the ultrasound probes to be subsequently used from the displayed selection screen, the controller controls the connection selector to connect the selected ultrasound probe with the apparatus body.
A biological information detector includes a light-emitting part subjected to emit a first light directed at a detection site of a test subject and a second light directed in a direction other than a direction of the detection site, a first reflecting part subjected to reflect the second light and directing the second light towards the detection site, a light-receiving part subjected to receive light having biological information, where the light produced by the first light and the second light is reflected at the detection site, and a second reflecting part subjected to reflect the light having biological information from the detection site and directing the light having biological information towards the light-receiving part.
An elongate robotic arm comprising articulated segments and a channel that extends along the longitudinal axis of the arm and contains a stiffening member which includes a sensor for measuring the shape of the arm. Using the central channel for this purpose improves the ease and accuracy of shape measurement.
An endoscope apparatus includes an insertion part which has an imaging mechanism at a distal end portion; a display part which displays an image acquired by an observation mechanism, a manipulating part which performs curving manipulation of the insertion part; and a housing which accommodates the display part and the manipulating part to a front face thereof, and which connects the insertion part with a back face opposite to the front face. The manipulating part has a swingable first joystick; and a curving mechanism having the first joystick and a manipulating member connected thereto. The swinging center of the first joystick is located inside a region specified by a portion where fingers are arranged in a side view of the housing when a user holds the housing, and by a distal end of the first joystick protruding toward the front face.
A penile prosthetic system includes a pump connected between a reservoir and an inflatable penile implant. The inflatable penile implant includes a cylinder and a distal end portion connected to a distal end of the cylinder along a major longitudinal axis of the cylinder. The distal end portion forms a fluid chamber that is in fluid communication with the cylinder, and a fluid conduit is integrally formed to communicate with the fluid chamber in the distal end portion. The fluid conduit has a minor longitudinal axis that forms an angle with the major longitudinal axis of 5 degrees or less.
A method of applying external electromagnetic fields to stimulate body tissues of a user. The method may include the steps of obtaining a distributor comprising a plurality of electromagnetic coils, obtaining a controller comprising a processor and a memory device, operably connected to one another, the memory device storing code executable by the processor, selecting a source of electrical current, connecting the source to the controller, and positioning a user proximate the distributor. The method may further include controlling, by the controller in accordance with the code, delivery of electrical current sequentially and exclusively to each coil of the plurality of electromagnetic coils to generate a magnetic field extending into the user.
A balance board adapted for riding rail-to-rail, preferably so that at least a portion of a rider's feet will be placed on the board over the elongated tube. The balance board includes an elongated, planar board having a length that exceeds a width. The balance board further includes two pair of stops mounted to an underside of the board, each pair of stops being mounted near opposite ends of the board, and each stop of the pair of stops being mounted near opposite sides of the board. The balance board further includes a traction region between each stop of each pair of stop.
A system and method for controlling a hybrid vehicle including a transmission having a torque converter with a bypass clutch include controlling the slip between the impeller and the turbine of the torque converter in slip mode operation to regulate the converter torque ratio and maintain substantially constant torque at the turbine. Controlled slip uses the hydrodynamic coupling of the torque converter to balance the desired and delivered torque while damping torque disturbances transmitted through the driveline to manage noise, vibration and harshness (NVH).
A load control system for a work vehicle including set rotation speed detection means for detecting a set rotation speed of an engine of the work vehicle, actual rotation speed detection means that senses an actual rotation speed of the engine, a continuously variable speed change device that receives power from the engine of the work vehicle, speed change position detecting means for detecting a speed change operating position of the continuously variable speed change device, operating means for speed-shifting the continuously variable speed change device, and control means for controlling the operation of the operating means.
An automatic transmission includes an input shaft or member, an output shaft or member and three simple and one compound planetary gear assemblies each including a sun gear, a planet gear carrier with a plurality of planet gears and a ring gear. The input shaft or member is coupled to the sun gear of the second planetary gear assembly and the output shaft is coupled to the planet gear carrier of the fourth planetary gear assembly. The transmission also includes six torque transmitting devices: one band brake, three friction brakes and two friction clutches.
A transmission of the present invention has an input member, an output member, four planetary gear sets, a plurality of coupling members and a plurality of torque transmitting devices. Each of the planetary gear sets includes first, second and third members. The torque transmitting devices may include clutches and brakes. The torque transmitting devices are each selectively engageable in combinations of at least three to establish a plurality of forward speed ratios and at least one reverse speed ratio.
A transmission is provided having an input member, an output member, a planetary gear set assembly, two planetary gear sets, a plurality of coupling members and a plurality of torque transmitting devices. Each of the planetary gear sets includes first, second and third members and the planetary gear set assembly includes first, second, third and fourth members. The torque transmitting devices include clutches and brakes actuatable in combinations of two to establish a plurality of forward gear ratios and one reverse gear ratio.
Devices and methods for illuminating an arrow nock or bolt end are disclosed including providing a nock having a first portion adapted to receive the bowstring in a drawn position and a second portion adapted to receive the bowstring after the bowstring is released from the drawn position; a light source assembly at least partially disposed within the nock body and activated when the bowstring is released from the drawn position; the light source assembly comprising a power source, a light source and a switch; and at least a portion of the light source assembly protruding from the end of the nock body so that releasing the bowstring causes the switch to close, thereby activating the light source and illuminating the nock or bolt end. Other embodiments are described and claimed.
Collars are provided to facilitate retaining the blades of a broadhead in their in-flight position during flight. Collars can be used in situations where the preexisting use of an O-ring is used to help facilitate maintaining he blades of a broadhead in their in-flight position during flight. Collars can also be used in situations where the preexisting use of an O-ring is not used to help facilitate maintaining he blades of a broadhead in their in-flight position during flight.
A weighting device for use with a racket includes at least one frame strip, at least one weight, and at least one screw. The frame strip is adapted for being mounted on an outer circumference of a racket frame and has a dovetail groove extending along a longitudinal direction thereof, and a plurality of through holes provided at a bottom wall of the dovetail groove. The weight has a threaded through hole and is slidably engaged in the dovetail groove. The screw is threadedly engaged with the threaded through hole of the weight and provided with an end stoppable against the bottom wall of the dovetail groove for holding the weight stationarily. Therefore, the weight can be firmly positioned and the balance of a racket using the weighting device can be quickly adjusted by adjusting the position of the weight.
The subject innovation includes a rebound device which is capable of receiving a ball or any object projected by a user in a substantially downward direction and projecting the same ball or object back to the user in a substantially upward direction in order to allow the user to catch through the use of a rebound surface or net. The rebound surface or net is positioned and angled to receive balls or objects projected downwards from any side of the user and to return or propel those projected balls or objects back to the user.
Iron golf club heads and clubs include a body having a ball striking face, a rear face opposite the ball striking face and a sole portion positioned between the ball striking face and the rear face. The rear face has an opening in communication with a slot positioned in the body. A weight element is positioned in the slot through the opening. The weight element has at least one aperture wherein the center of gravity is shifted when the weight element is positioned in the slot.
A golf club with a multi-material face is disclosed herein. More specifically, the golf club head in accordance with the present invention has a striking face that forms a pocket, wherein the pocket is filled with a secondary material having a lower density to improve the performance of the golf club head. The multi-material face disclosed in accordance with the present invention may generally have a characteristic time slope of greater than about 5 and less than about 50, wherein the characteristic time slope is determined based on the various data points collected according to the United States Golf Association's (USGA's) Characteristic Time (CT) test.
An improved golf club shaft comprised of a flexible insert device that adds additional flexibility to said club shaft and creates one or more pivot points along said shaft. The increased flexibility of the golf club shaft enables a golfer to impart greater force on a golf ball, and also dampens or reduces the amount of vibration and/or shock otherwise imparted to the golfer when the golf club head strikes the golf ball.
A golf club head comprising an aerodynamic hosel is disclosed herein. In one embodiment, the hosel has an upper portion and a swept transition portion which connects to the golf club head, and all points at which the swept transition portion contacts the club head are spaced rearwardly from a vertical face plane. In a further embodiment, both the upper portion and the swept transition portion comprise coaxial shaft receiving bores. In yet another embodiment, the swept transition portion of the hosel has a trailing edge that is truncated, or that has one or more surface discontinuities. In yet another embodiment, the swept transition portion has a height and a diameter, each of which is less than or equal to one inch.
A method of dynamically linking abstracted hardware devices, which are used in association with gaming machines, to gaming software. The game machine has a communication link that connect a plurality of intelligent Input/Output controller boards (“IOCB”) to hardware devices interfaced to the game. An I/O communication driver scans for a primary IOCB. Once the primary IOCB is found, I/O communication drivers are loaded for any secondary IOCBs.
A method for providing an activity involving a plurality of users in a plurality of virtual communities is disclosed. The method includes the steps of (a) creating the plurality of virtual communities based on the resources accessed or actions taken by the plurality of users, (b) keeping track of each of the plurality of user's resources accessed or actions performed, and (c) enabling the activity based on the resources visited and actions performed by each of the plurality of users.
A gaming system is disclosed that comprises a plurality of rotatable reels, each reel comprising a plurality of selectable symbols corresponding to respective reel stopping positions. The system includes a symbol selector arranged to select a stopping position for each reel and thereby select at least one symbol from each reel, and a reel controller arranged to control rotation of the reels such that the reels rotate during implementation of a game in order to move the reels to the selected stopping positions and thereby display the selected symbols in a display area. The reel controller is arranged to control rotation of the reels such that each reel rotates less than one full rotation to the selected reel stopping position. A corresponding method of gaming is also disclosed.
A gaming machine includes a button panel having a front surface, wherein at least a portion of the front surface is an optically restrictive material, and a plurality of light devices aligned relative to the optically restrictive material. The gaming machine also includes a controller coupled to the plurality of light devices, wherein the controller is configured to control at least one of an order of illumination for at least a portion of the plurality of light devices and a duration of illumination for at least a portion of the plurality of light devices.
A method and system to transfer assets between interactive social games is described. In some embodiments, the method generates a visual expression of a transfer mechanism in a first computer-implemented game. The method further generates the visual expression of the transfer mechanism in a second computer-implemented game. The transfer mechanism is capable of transferring an in-game asset from the first computer-implemented game to the second computer-implemented game. The method transfers the in-game asset from the first computer-implemented game to the second computer-implemented game using the transfer mechanism.
The apparatus includes memory for storing prize values and an input device being responsive to a plurality of gaming terminals for providing an increment signal which adjusts an accumulated value. A comparator determines when the current prize value to be awarded, reaches the accumulated value generates an award signal and removes from the one of the sets the prize awarded. A controller responsive to the award signal determines if the one of the sets includes at least one remaining prize value and, if so, actuating the increment device to define the current prize value as the at least one remaining prize value.
A plurality of gaming terminals each having a terminal display on which a plurality of symbols are provided, a plurality of upper displays forming a single common effect display screen which is constituted by gaming terminal areas corresponding to the respective gaming terminals, and a center controller are provided. When the common game starts, the center controller displays a common game start effect image on a common effect display screen and transmits a common game start effect image display command to the gaming terminals so that the common game start effect image divided for respective gaming terminal areas is displayed on the terminal display of each of the gaming terminals corresponding to the gaming terminal areas.
A gaming machine executes a process with new entertainability. The game executes a normal game accepting an input of selecting any of the plurality of the specific symbols stop-displayed, in response to a fact that a plurality of the specific symbols are stop-displayed, in the normal game executed. A benefit is awarded according to the specific symbols selected. Whether or not to generate a specific game state is determined, in response to the specific symbols selected. An input of selecting a specific symbol other than the specific symbol previously selected is accepted from among the plurality of specific symbols stop-displayed, in response to a fact that it is determined that the specific game state has been generated. A benefit is awarded according to the specific symbol selected in the last processing.
Some embodiments may relate to method or apparatus that allow a user to choose a source of random numbers or other information that may be used as the basis for a game. Other examples of methods, apparatus, games, embodiments, and so on are described.
A system and method for transmitting a P2P message in a multi-access online game is disclosed. The system includes a game server for receiving game messages from a first user client, processing the received game messages, and transmitting game messages, needed to be transmitted to a second user client, to the second user client; and a database (DB) server for receiving status change information, and storing the received status change information in a database, wherein the game server, upon receiving a request of the second user client, having received a game message from the first user client as a P2P message, blocks the game message from being transmitted to the second user client. Therefore, some parts of transmission messages of the game server are transmitted or received as the P2P messages by the user clients, resulting in reduction of load at the game server.
A safety use deboning knife includes a blade having a distally disposed carcass flesh penetration tip disposed immediately adjacent the blade curved cutting edge and spacedly disposed from the blade non-cutting upper edge by a planar distal edge, which distal edge subtends an acute angle of less than about 45° and preferably in less than about 25° with entire cutting portion disposed below the blade center line.
An internal gear grinding machine achieves space savings and reduction in size of a machine, as well as prevents the tools from being damaged even when an abnormal situation such as a blackout occurs, by a simplifying dressing operation. The internal gear grinding machine for grinding a workpiece (W) by synchronously rotating the workpiece (W) and a barrel-shaped threaded grinding wheel (17) in mesh with each other includes a dressing device (20) for dressing the threaded tool (17) by meshing the threaded grinding wheel (17) with a disk dresser (56). When dressing, the threaded grinding wheel (17) and the disc dresser (56) are operated in accordance with the helix angle and barrel shape of the threaded grinding wheel (17), and the brake mechanism (58) applies a braking force to a dresser turn drive motor (53) to enable the disc dresser (56) to be maintained at a turned position thereof.
Methods of abrading surfaces by rotationally reciprocating abrasive surfaces in contact with the surfaces, abrasive articles for use in rotationally reciprocating tools, and methods of removing defects in a surface, where the methods include sanding using a rotationally reciprocating abrasive surface followed by one or more polishing operations are disclosed.
A toy motorcycle for use on a track with a guide groove includes an electric motor, a chassis, and a support structure mounted on the bottom of the chassis that includes at least two support wheels and a magnet. A guide mounted on the support structure is configured to engage the guide groove of a track. A frame is associated with the chassis, and a rear traction wheel and a front wheel are mounted on the frame. The rear traction wheel is operatively coupled to the electric motor. The toy motorcycle includes a tilting system that tilts the frame when the toy motorcycle is traversing a curved section of a track. The tilting system also causes the rear wheel to traverse a different curve trajectory than the guide groove of the track.
The invention relates to a drive device (1) for water vehicles comprising a propeller (2), a drive mechanism (3) for driving the propeller (2), and a magnetic coupling (4) which is arranged between the propeller (2) and the drive mechanism (3), wherein the magnetic coupling (4) comprises an outer magnetic element (7), an inner magnetic element (9) and a can (11), and wherein the can (11) is arranged between the inner magnetic element (9) and the outer magnetic element (7).
A electrical interconnect adapted to provide an interface between contact pads on an IC device and a PCB. The electrical interconnect includes a multi-layered substrate with a first surface with a plurality of first openings having first cross-sections, a second surface with a plurality of second openings having second cross-sections, and center openings connecting the first and second openings. The center openings include at least one cross-section greater than the first and second cross-sections. A plurality of spring probe contact members are located in the center openings. The contact members include first contact tips extending through the first opening and above the first surface, second contact tips extending through the second openings and above the second surface, and center portions located in the center openings. The center portions include a shape adapted to bias the first and second contact tips toward the IC device and PCB, respectively. A dielectric material different from the material of the substrate is located in at least one of the first opening, the second opening, or the center opening.
A multiple contact connector comprises a plurality of terminal pieces arranged linearly in the lengthwise direction, and an insulating provided with a plurality of dividing walls extending between the terminal pieces for supporting the terminal pieces and for insulating between adjacent terminal pieces, having the insulating pieces inserted into terminal supporting spaces between the separating walls.
A terminal load includes an insulating cylinder internally defining a receiving space having a locating surface, and having a front open end and a rear end provided with a notch; an insulating cap mounted to the front open end of the insulating cylinder; a circuit board mounted on the locating surface to rearwardly project a rear narrowed section from the notch; a connection terminal electrically connected with the circuit board to forward extend through the insulating cap; and a conductive cap having a top hole and fitted around the rear end of the insulating cylinder with the rear narrowed section of the circuit board extended through the top hole and clamped between two contacting arms at two opposite sides of the top hole. The terminal load with the above structure can be driven by punching to safely assemble to an outer housing, and the conductive cap ensures good conducting effect.
A coupling member including a body defined by an inner surface and an outer surface between a first end and a second end, at least one resilient contact extending a distance from the inner surface of the body, the at least one resilient contact configured to provide a retention force, and at least one resilient protrusion extending a distance from the inner surface of the body, the at least one resilient protrusion positioned proximate the second end of the body and configured to contact a conductive surface is provided. A cable connector for mating with an interface port having external threads, comprising a coupling member attached to the post, the coupling member having one or more resilient contacts and resilient protrusions, wherein the resilient contacts are configured to provide a retention force between a coupling member and a port and the resilient protrusions facilitate electrical continuity through the connector is further provided. Furthermore, associated methods are also provided.
In the field of telecommunication and data transmission, a jack support structure for fixing a plurality of modular telecommunications jacks on a patch panel. The jack support structure has at least two parallel rows of jack cavities, and fixing means for fixing the jack support structure on a patch panel, characterized by the fixing means being positioned only between two adjacent rows.
A patch cord assembly is provided for detachably securing a first patch cord relative to a second patch cord, defined by a first patch cord that includes a first elongated cord and a first plug mounted with respect to one end of said first elongated cord, and a second patch cord that includes a second elongated cord and a second plug mounted with respect to one end of said second elongated cord. A method of patch cord assembly is provided for detachably securing a first patch cord relative to a second patch cord. A system of patch cord assembly packaging and payout is provided including a housing for packaging a patch cord assembly and at least one housing opening for paying out the at least first patch cord.
An electrical insulation displacement connector includes a bare single-wire contact element having a first end defined by opposed blades that define a receipt aperture for an insulated wire, and a second end configured for direct electrical contact at a contact position on a printed circuit board. Retaining structure is defined on the blades. A cap is configured for fitting over the exposed bare blades. The cap includes side walls and end walls with a slot defined in each of he end walls that align with the blade aperture. The side walls are engaged by the retaining structure upon pressing the cap onto the blades. The slots in the end walls of the cap have a width and height such that upon fully pressing the cap onto the blades, the slots engage and longitudinally align the insulated wire into the blade aperture so that the blades pierce and make electrical contact with a core in the insulated wire.
An electrical component assembly includes a first electrical component having a PCB mounted therein. The PCB includes a plurality of female sockets. A second electrical component includes a plurality of PCB engagement members and a plurality of pins. The first and second electrical components each include an alignment feature. The first and second electrical components are configured to be aligned and connected by progressively bringing together the first and second electrical components. In a first position, the first and second electrical components are spaced apart a first distance and the alignment features of the first and second electrical components are engaged. In a second position, the first and second electrical components are spaced apart a second distance and the PCB engagement members engage the PCB. In a third position, the first and second electrical components are spaced apart a third distance and the female sockets receive the pins.
An electrical connection system includes a first connector housing including electrical contacts and a second connector housing including corresponding electrical mating contacts. The first connector housing and electrical contacts are configured to mate with the second connector housing and the electrical mating contacts along a mating axis. At least one of the first and second connector housings includes a sealing member that surrounds the electrical contact associated with the at least one of the first and second connector housings and further contains a retaining means to retain the sealing member therein. The retaining means is integrally formed with the connector housing. A method to construct the electrical connection system that includes the sealing member and the integral retaining means is also presented.
A connector mechanism includes a first casing, a second casing, a rotary cover, a circuit board, a socket, a base, a rotary fastener and a resilient component. The rotary cover is connected to the second casing in a rotable manner. The rotary fastener is pivoted to the base. The rotary fastener is pressed by the rotary cover when the rotary cover rotates to a close position. The rotary fastener fastens a plug when the rotary cover rotates to an open position so as not to press the rotary fastener and when the plug is inserted into the socket. The resilient component is connected to the rotary fastener for driving the rotary fastener to fasten the plug when the rotary cover rotates to the open position.
A device includes one or more connectors and receptacles. The connector may include a pair of connector magnets. The connector may also include a pair of connector terminals positioned between the pair of connector magnets. The receptacle may be associated with a user device. The receptacle may include a pair of receptacle magnets that are configured to magnetically couple with the pair of connector magnets when brought within proximity of each other. The receptacle may also include a pair of receptacle terminals positioned between the pair of receptacle magnets that are configured to mate with the pair of connector terminals to form an electrical connection. In this manner, the connector and the receptacle may form an electrical connection when the pair of connector magnets is coupled with the pair of receptacle magnets, thereby mating the pair of connector terminals with the pair of receptacle terminals.
The present invention relates to a system and method for periodic evaluation and telerehabilitation in which a portable device is adapted to be held or coupled to a body part. For example, the portable device can be a cell phone. The body part can be, for example, the hand, ankle, torso, forearm or upper arm. An animated or virtual reality sequence forming a videogame runs or the portable device. Upon interaction of the user with the videogame, movement of the body part is captured as exercise data. The exercise data can be forwarded and stored at a remote clinical server. The system provides monitoring and scheduling of a therapy session by a clinician/doctor/therapist to control the exercises, length and/or difficulty of the exercises based on recorded data. In one embodiment, vital signs or body temperature are monitored by sensors on the portable device or by vital sign monitors associated with the user. The vital sign data can be synchronized with the exercise data at the remote clinical server, and used to improve patient safety during home therapy sessions.
The extrusion head including a conduit with a central mandrel extending within the conduit for supporting an inner die portion of a set of dies that has inner and outer die portions. An upstream spider and a downstream spider are included, and each have webs supporting the central mandrel at axially spaced apart positions. The webs of the upstream and downstream spiders can have web portions that are axially offset from each other to promote mixing of polymer flowing through the conduit.
An injection molding system is disclosed that includes a mold insert set and a shaft locking assembly that releasably attaches the mold insert set to a mold plate of the injection molding system. Each mold insert of the mold insert set defines at least a portion of a mold cavity. The shaft locking assembly is displaceable between a locked position in which the mold insert set is held to the mold plate and an unlocked position in which the mold insert set is removable from the mold plate.
An air compression device is applied in an air compressor, and mainly includes a first rotor, a second rotor, a stop disk, a transmission element and a drive element. When external air enters an air chamber in the air compression device, the air is rotated and compressed by the first rotor and the second rotor, and then is exhausted, the transmission element generates axial displacement vertically according to actual requirements on air admission or exhaust, and drives the drive element and the first rotor to displace, so as to change a capacity of the air chamber, and adjust the air output.
Detecting a failure mode of a fluid flow controller configured to control fluid flow between first and second chambers of a downhole positive displacement pump and a flow line, wherein the positive displacement pump comprises a piston moving in an axial reciprocating motion, and subsequently adjusting operation of the downhole positive displacement pump based on the detected failure mode such that the downhole positive displacement pump piston operates differently in different axial directions.
A method of minimizing the flow of hydraulic fluid within a hydraulic accumulator mounted in the rotating hub of a wind turbine comprises mounting the accumulator within the hub such that the longitudinal axis of the accumulator is substantially parallel with the axis of rotation of the hub.
A cooled airfoil includes an impingement rib having a multiple of openings which supply a cooling airflow from a cooling circuit flow path toward an airfoil leading edge. The multiple of openings are offset in the impingement rib opposite an outer airfoil wall which includes gill holes. Offsetting the multiple of openings opposite an outer airfoil wall which includes the gill holes focuses the cooling airflow across turbulators to increase the cooling airflow dwell time to increase the thermal transfer therefrom in higher temperature airfoil areas.
An adjusting device for adjusting the rotation angle position of the rotor of a wind energy system should be improved by the invention, whereby a complicated processing of the brake disc previously used for engagement of the drive is no longer necessary, and whereby said brake disc can be flexibly arranged in an area with sufficient construction space. For this purpose, the adjusting device has at least one force transducer wheel and/or a force transducing disc which is mounted or can be mounted on a shaft (1) of the drive train which is switched downstream from the rotor, which is structured for engagement of a force transmitting means, and is designed as an independent component. The device also has a drive means for producing a drive force, and at least one force transmission means for transmitting the drive force to the force transducer wheel and/or the force transducing disc.
A stationary vane assembly of a turbine engine including an inner casing and a high-pressure turbine guide vane assembly including at least two angular sectors including blades, the angular sectors being fixed on the casing, each angular sector including a platform and a fastening tab. The fastening tab protrudes from the platform radially inwardly. The casing includes a first annular groove receiving the fastening tabs, radial retaining pins for the angular sectors being introduced into bores made in the casing and the fastening tabs, the axial retaining pins being axially stopped by a ring mounted in a second annular groove of the casing.
The maritime transfer system is for crewmember safety when transferring to and from a vessel to a small oil or gas production platform that otherwise has only a swing rope for transfer. The system includes a platform extension permanently affixed to the platform, and a motor and winch installed on the extension. The motor and winch operate a cable that extends to a davit, the davit and cable suspending a car or gondola therefrom. Control is provided by a remote control switch installed on the distal end of a freely suspended control cable. In this manner, the car may be raised to the platform when not in use, the control hanging from the control cable for access from the crew vessel when needed. The crewmember may then carry the control with him or her in the car as it is raised and lowered to and from the platform.
A chuck-knockout assembly for seaming a can end onto a can body to form a seamed container is disclosed. The chuck-knockout assembly may include an upper chuck body and a lower chuck body. The upper chuck body may include a first drive surface and may be rotatably coupled to a seaming machine frame. The lower chuck body may include a second drive surface and may be longitudinally moveable relative to the upper chuck body. The second drive surface may be configured to engage a periphery of the can end during seaming and disengagement of the container.
A self-countersinking fastener for engagement with wood or similar composite material, said fastener including a penetrating shaft, and a tool engaging head; wherein said tool engaging head is substantially frusto-conical in overall shape and provided with one or more indent regions into which said material may be pushed as the head is turned; wherein each of said indent regions include: a trench extending substantially vertically through the entirety of said head; and a tailing section extending through the entire height of the head and extending forward in the direction of turning from said trench such that the radius of the head in the corresponding section increases throughout said section.
An adjustable decking system for use in supporting freight is provided. The system includes a pair of tracks configured to be vertically mounted upon opposite walls of a freight container, configured with a plurality of evenly spaced recesses disposed along the length thereof. A bracket is slidably mounted upon the pair of tracks and a lock is pivotably mounted to the bracket and an end of the channel unit. The lock includes first, second, and third fingers extending therefrom which are normally received within three of the plurality of spaced recesses disposed along the track. The lock is being pivotably mounted to the bracket such that the first, second, and third fingers may be withdrawn from the three of the plurality of spaced recesses to allow the position of the channel unit to be vertically adjusted along the one of the pair of tracks.
A positioning apparatus for positioning an object in respective axis directions of an X-axis, a Y-axis perpendicular to the X-axis, and a Z-axis orthogonal to the X-axis and the Y-axis and positioning the object around the Z-axis within a plane parallel to the X-axis and the Y-axis is provided. A fastener detachably fastens the retainer. A gap is formed between a first reference surface of the retainer and the second reference surface of the fastener when a fixing shaft of the retainer is inserted into a fixing hole of the fastener, an outer surface of a pyramid part of the fixing shaft fits to an inner surface of the fixing hole and the object is positioned in the X-axis direction and the Y-axis direction. The first reference surface and the second reference surface come into contact with each other when a fastening part of the fastener pulls the fixing shaft, the pyramid part or the fixing hole elastically deforms, and the fixing shaft is further pulled into the fixing hole with maintaining the fitting between the outer surface of the pyramid part and the inner surface of the fixing hole.
A quick-connect mounting apparatus used to join a drive mechanism to a driven mechanism permits rotatable members of the drive mechanism and driven mechanism to be aligned and joined together for proper operation.
A writing instrument accessory for use with a writing instrument includes a sleeve having a tubular configuration defining upper and lower ends, the sleeve being configured to receive the writing instrument. The accessory includes an elastic member coupled at one end to the sleeve and extending away from the sleeve to another end opposite the sleeve, the elastic member having a stretchable and resilient configuration. A hook member is coupled to the elastic member at the end opposite the sleeve, the hook member having a configuration complementary to a shape of a person's finger so as to be selectively coupled thereto. In operation, the elastic member is held at length by a user's non-writing hand finger from the writing instrument while a writing task is undertaken by the user.
A tape cassette that includes a generally rectangular box-like housing having a top wall, a bottom wall, and a side wall defining a periphery of the housing, at least one tape wound and mounted within the housing in a tape containing area defined within the periphery, and a pair of cavities extending from the bottom wall and disposed between the tape containing area and the periphery at opposite ends of a diagonal of the generally rectangular box-like housing, the diagonal connecting a first corner portion and a second corner portion of the generally rectangular box-like housing.
A recording device has a recording unit that records on a recording medium, a transportation unit that conveys and discharges from an discharge opening the recording medium recorded by the recording unit, a cutting unit that cuts the recording medium recorded by the recording unit at a predetermined position on the transportation path of the transportation unit, and a control unit that causes a ticket to be output by causing the recording unit to record on the recording medium while causing the transportation unit to convey the recording medium only a specified ticket length and causing the cutting unit to cut. When a next ticket is not output after a ticket is output, the control unit causes the output ticket to be recorded and conveyed the specified ticket length, advanced a preset additional transportation distance, and then cut by the cutting unit.
A communications connection system includes an SC fiber optic connector including a storage device having memory configured to store physical layer information. The storage device also includes at least one contact member that is electrically connected to the memory. The communications connection system also includes a fiber optic adapter module having one or more media reading interfaces. Each media reading interface is configured to read physical layer information stored on one of the fiber optic connectors received at the adapter module. Certain types of media reading interfaces extend between an internal passage of the adapter module and an external surface of the adapter module.
A method of determining the temperature of a sample carrier in a charged particle-optical apparatus, characterized in that the method comprises the observation of the sample carrier with a beam of charged particles, the observation giving information about the temperature of the sample carrier. The invention is based on the insight that a charged particle optical apparatus, such as a TEM, STEM, SEM or FIB, can be used to observe temperature related changes of a sample carrier. The changes may be mechanical changes (e.g. of a bimetal), crystallographic changes (e.g. of a perovskite), and luminescent changes (in intensity or decay time). In a preferred embodiment the sample carrier shows two bimetals, showing metals with different thermal expansion coefficients, bending in opposite directions. The distance between the two bimetals is used as a thermometer.
An apparatus and methods for characterizing the response of a particle to a parameter that characterizes an environment of the particle. A change is induced in the parameter characterizing the environment of the particle, where the change is rapid on a timescale characterizing kinetic response of the particle. The response of the particle is then imaged at a plurality of instants over the course of a period of time shorter than the timescale characterizing the kinetic response of the particle. The response may be detected by measuring a temperature jump or by measuring correlation and anticorrelation between probe parameters across pixels. More particularly, the particle may be a molecule, such as a biomolecule, and the environment, more particularly, may be a biological cell. The parameter characterizing the environment of the particle may be a temperature, and change may be induced in the temperature by heating a volume that includes the particle, either conductively or radiatively. The volume may be heated by means of a laser, such as an infrared laser, for example, or by microwave heating.
A method for calibrating distributed temperature sensing (DTS) systems is disclosed. The method includes: receiving temperature data associated with one or more locations along a length of an optical fiber; calculating a set of unique calibration coefficients specific to each of the one or more locations along the fiber length; and applying the set of calibration coefficients specific to each of the one or more locations along the fiber length to the temperature data for calibrated correction thereof. Also disclosed is a system for calibrating DTS data and a wellbore for providing calibrated DTS data.
Conveyor apparatus and methods of conveying a foodstuff. A foodstuff conveyor apparatus may include a foodstuff inlet, a foodstuff outlet, and a conveyor chamber coupling the inlet to the outlet. A conveyor screw having an axis oriented longitudinally in the conveyor chamber may be configured to urge the foodstuff from the inlet towards the outlet. The conveyor screw may have a spindle at each end, with a spindle free portion between the spindles. The screw may be positioned in the conveyor chamber so that one spindle is near the outlet, and the other spindle is near the inlet. The spindles may be configured so that the pitch of the screw near the outlet is less than the pitch of the screw near the inlet to provide a mixing and compacting effect as the foodstuff is conveyed from the inlet to the outlet.
A lamp unit for forming a light distribution pattern having a given cutoff line in an upper end portion thereof includes a light source, a transparent member which receives light from the light source from rearward and projects the light distribution pattern forward, and a light shade which is provided between the light source and the transparent member and which shades a part of the light emitted by the light source. The transparent member is configured to reflect, by a front surface of the transparent member, the light that enters the transparent member from rearward thereof, then to reflect again the light to forward thereof by a rear surface of the transparent member, and then to radiate the light from the front surface. The light shade is configured to shade the light going from the light source directly toward the rear surface.
An improved heat sink for a lighting fixture includes an inner heat sink conductively coupled to a lighting subassembly, a plurality of cooling fins conductively coupled to and extending away from the inner heat sink, and an outer heat sink coupled to the cooling fins and offset from the inner heat sink. The outer heat sink includes a lower heat sink coupled to a first set of cooling fins mounted on the inner heat sink, and an upper heat sink coupled to a second set of cooling fins. A plurality of air vents extend through the outer heat sink and are aligned with a corresponding plurality of the first set of cooling fins.
A lighting device may be provided that includes a heat sink which includes one surface and a receiving recess; a light emitting module which is disposed on the one surface of the heat sink and includes a substrate and a plurality of light sources disposed on the substrate, wherein the substrate includes a hole and a plurality of via-holes; a power controller which includes an electrode pin electrically connected to the light emitting module through the via hole; and aninsulating inner case which receives the power controller therein and is disposed in the receiving recess of the heat sink, wherein the light sources include an lighting emitting diode.
An embodiment of the disclosed technology discloses a backlight source and a display device. The backlight source including a back plate, an optical film, a light source bracket located between the back plate and the optical film, and a light source mounted onto the light source bracket; the light emitted from the light source is radiated toward the optical film after being reflected by the back plate.
A file system for a stage lighting system that maintains the different files associated with the stage lighting system. Each of the files that can represent an effect are maintained within the system within a configuration file. The configuration file can be updated on each start of the system so that the system can maintain information indicative of current configuration files. A test mode can also be entered in which a pre-formed show can be tested against the current state of the configuration files.
Self-aligning mechanisms hold a condenser housing. The condenser housing is moved toward an integrator while tapered surfaces of the condenser housing of an LED light source unit are inserted along condenser lens guides of a projection unit. LED light source unit datum surfaces and datum surfaces of the projection unit abut against each other, and the tapered surfaces of the LED light source unit can no longer move toward the integrator along the condenser lens guides of the projection unit. In this state, the LED light source unit and the projection unit are coupled to each other.
A projector includes a projection lens set, a DMD, a prism unit, a light guide unit, and a light source device. The light source device includes a first and a second LEDs, a laser light source, and a color wheel. The first LED is positioned in a first optical path and generates a first light. The laser light source is positioned in a second optical path and generates a laser light. The second LED is positioned in a third optical path and generates a second light. The laser light irradiates the color wheel to generate a third light. A light merging unit merges the first, second, and third lights. The light guide unit guides the mixed light to the prism unit. The mixed light is refracted to the DMD via the prism unit. The refracted mixed light is reflected to the projection lens set via the DMD.
A system and associated methods for animated image vision testing is disclosed. In at least one embodiment, a vision test includes at least one animated dynamic optotype image for measuring the visual acuity of a subject. The animated image vision test takes advantage of the ability of the human eyes to detect both distance and motion. Moving images, such as rotating segmented circles, let the eyes detect motion as to the size, distance, and rotation direction of that moving image. That motion detection is much more precise than the interpretation of multiple static letters or static images. Using rotating images for vision testing rather than static images creates an acuity test more accurate than current tests, a test that is faster to use, and a test that does not require the ability to read.
The invention relates generally to optical tomographic imaging and in particular to systems and methods for adapting the resolution of imaging. One embodiment of the present invention is an apparatus for optical coherence tomography imaging, characterized by its ability to vary the axial resolution and scanning speed during imaging.
Implementations described and claimed herein provide a complex surface of a progressive multifocal ophthalmic lens. In one implementation, the complex surface includes: a difference in ratio between cylinder value and surface addition less than 0.2 in absolute value; a first ratio between a maximum cylinder value for all points in a grouping circle and a surface addition; and a second ratio between a maximum cylinder value for all points on a disc and a surface addition. In another implementation, the complex surface includes: a difference in ratio between resultant astigmatism value and prescribed addition less than 0.3 in absolute value; a first ratio between a value of resultant astigmatism for all directions of gaze passing through an angular circle and a surface addition; and a second ration between a value of resultant astigmatism for all directions of gaze passing inside the angular circle and a prescribed addition.
An elastic constraint system for a pair of eyeglasses includes at least one inextensible flexible wire provided with two wire terminals to be engaged with two distinct portions of an eyeglasses front frame or temple bars, at least one of the wire terminals being provided with an elastic element mounted preloaded and acting in opposition to a tensioning of the inextensible flexible wire.
The present disclosure relates to a frame which comprises a front surface, extended by two lateral posts and two arms hinged to the posts about the hinge pins of two telescopic hinges, each of which, with a front surface element rigidly connected to a post and an arm element, is rigidly connected to an arm that comprises a slide hinged on the front surface element, and mounted in a sheath against a spring and slidable by means of the latter; the front surface element and the sheath of the arm element engaging, in the open position of the arm, by at least two matching transverse surfaces for stopping the opening. The surfaces that stop the opening of the two elements of each hinge are rough, the surface that stops the opening of one of the elements, of the surface, and of the arm having a hollow intermediate area. Thanks to the present method, system and device, the frame hinges have a reduced size with the same performance.
A liquid dispenser includes a first liquid chamber and a second liquid chamber. The first liquid chamber includes a nozzle. A heater is associated with the second liquid chamber. A flexible corrugated membrane is positioned to separate and fluidically seal the first liquid chamber and the second liquid chamber from each other.
An inkjet printer includes: an inkjet printhead having an exposed corrodible structure containing silicon nitride, borophosphosilicate glass (BPSG) or silicon oxide; and an ink reservoir containing said ink which is in fluid communication with said printhead. The ink includes: water; a dye; and a metal additive for minimizing corrosion of the exposed structure.
Electronic circuitry compensates for variations or sags in electrical voltage within a thermal ink-jetting (TIJ) printing apparatus. Ground potential and other supply-related voltages are monitored and corresponding signals are provided. The signals are used, directly or by other circuitry, to affect the biasing of one or more transistors coupling TIJ resistors to supply voltage or ground nodes. Printing errors and related problems associated with voltage variations are reduced or eliminated accordingly.
A liquid ejecting head includes: a main head unit that ejects ink; a first flow channel member and a second flow channel member that include first and second flow channels, respectively, through which ink to be supplied to the main head unit flows; and a ring-shaped sealing member pinched by the first flow channel member and the second flow channel member. The first flow channel and the second flow channel communicate with the interior of a space area defined by the first flow channel member, the second flow channel member, and the sealing member, and an atmosphere exposure channel that connects the space area with the exterior is formed in a joining surface between the sealing member and the first flow channel member.
The liquid ejection head capable of securing a high performance of supplying liquid through supply ports while reducing the size of the substrate is provided. The liquid ejecting apparatus using such a liquid ejection head are also provided. The third supply ports situated between the first ejection port array and the second ejection port array include a portion of a large dimension and a portion of a small dimension.
An image forming apparatus includes a recording head, a waste liquid receiving member, a waste liquid tank, a needle member that is connected to the waste liquid receiving member and includes a needle part that is detachably inserted into the waste liquid tank, and a fastening member that detachably fastens the needle member. The fastening member includes a lock part that locks the needle member; the needle member includes a lock lever part that locks with the lock part of the fastening member; the needle member and the fastening member include fitting parts that fit together when the needle member is rotated; and by rotating the needle member, the lock lever is locked with the lock part, the fitting parts of the needle member and the fastening member are fit together, and the needle member is fastened to the fastening member.
A liquid ejection apparatus includes: a liquid ejection head; a long wiping member configured to come in contact with and wipe a liquid ejection face of the head; a wiping member conveyance device configured to convey the wiping member in a lengthwise direction of the wiping member; an elastic member configured to elastically deform and apply a force to cause the wiping member to be pressed against the liquid ejection face through a pressing member when the wiping member comes in contact and pressed against the liquid ejection face; and a slack eliminating member arranged in a front side of the head in a direction of travel of the head with respect to the wiping member, the slack eliminating member being configured to eliminate slack in the wiping member caused by elastic deformation of the elastic member when the wiping member comes in contact with the slack eliminating member.
A method of halftoning of an image comprising a pseudo-noise pattern of dots, whereby vectors between each dot and the nearest neighboring dot are orientated in a direction perpendicular to a line feed direction, and a density of the pattern of dots in a line feed direction is half of a density of the pattern of dots in a direction perpendicular to the line feed direction.
A printing apparatus includes a plurality of inkjet print heads to which humidified air is supplied to retain the humidity in the print heads. Ink colors for the plurality of heads are arranged in a sequence corresponding to ink characteristics. The plurality of print heads are arranged in a sequence such that a print head configured to eject ink characterized by having a larger amount of volatile components evaporated within a predetermined time is located in a more upstream area.
The present invention has an object to provide an inkjet printing apparatus that can realize both high quality image formation and improvement of a device life caused by the reduction of a mist amount of a processing liquid. The present invention is provided with a control unit that can independently control an ink ejection condition in an ink ejection unit and a processing-liquid ejection condition in a processing-liquid ejection unit. The control unit controls the ejection condition in each ejection unit so that the mist amount of the processing liquid ejected from the processing-liquid eject unit is smaller than that of the ink ejected from the ink eject unit.
A method of controlling a liquid ejection head controls a liquid ejection head including a liquid pressurizing chamber, nozzles communicating with the liquid pressurizing chamber, and a pressure generating device that generates pressure in the liquid pressurizing chamber based on a drive waveform. The method includes generating a preliminary ejection drive waveform with a predetermined number of successive drive pulses aligned in descending order of length of drive pulse intervals of the drive pulses, with each of the drive pulse intervals set to an integral multiple of a natural vibration period of the liquid pressurizing chamber, and applying the generated preliminary ejection drive waveform to the pressure generating device to cause the liquid ejection head to perform a preliminary ejecting operation.
What is disclosed is a multi-function system which receives media printed with ink having thermo-reactive properties with the ink being visually transparent on that media, and which processes that media such that the ink becomes visually perceptible. One embodiment of the present system comprises an input tray for receiving printed media into a transport path along which the media travels. A cooling element resides in proximity to that transport path for changing a temperature T of the media to T≦TL. A temp-normalizing element is positioned along the transport path downstream of the cooling element for changing a temperature of the media such that the media's temperature T can be normalized back to a temperature range TL
A mechanism for closing sliding doors of furniture. The mechanism includes at least two rotatable closing elements, each associated with a respective door. A locking body is associated with the closing element for rotating and locking the closing element in either an open position or a closed position. The closing element also includes a locking portion that, through the rotation of the closing element, can pass from a first position in which the locking portion prevents the translation of the sliding doors of the furniture, to a second position which allows the translation of the sliding doors. The closing mechanism also includes a synchronization bar that makes the closing elements rotate as a unit, ensuring the simultaneous locking of the sliding doors in the closed or open position.
Embodiments described herein improve airflow around the bicycle wheels by providing for one or more of: (1) a optimum leading edge width of a rim for preventing early stall in cross winds, while still allowing for sufficient stability without undue drag, while not unnecessarily increasing the rotating wheel and drag on the frame; (2) a sidewall shape with a subtle camber angle at the leading, which defines a rate of radius change at the max width of the rim—which further defines the max width and placement along the chord length for optimizing the aerodynamic properties of the rim; (3) a continuous rate of change of curvature at a spoke face, which fundamentally improves the performance and stability by generating a side force at higher yaw angles; and (4) wheel sets with a wider front rim relative to a narrower rear wheel to assist in flow attachment in high crosswind areas.
A method of maintaining a machine substantially level with a first surface is disclosed. The method may comprise determining an electronic travel path between a first point and a second point on a second surface, the second surface created by a tool removing a section of the first surface, and adjusting the length of the rear leg to maintain the frame substantially level to the first surface as the rear leg moves along the travel path from the first point to the second point in a forward direction. A machine for planing a road is disclosed that maintains a parallel orientation with the road during operation.
A table and seat assembly for limiting movement of ankle shackles by a client occupying the seat. The assembly includes a table supported by a first pedestal and the seat supported by a second pedestal, where the first and second pedestals are connected. A drive rod included in a locking mechanism extends from a linear sleeve bearing in the second pedestal and moves from an unlocked position in which the drive rod is not inside a receiver socket to a locking position in which the drive rod is inside the receiver socket. An individual positioned behind the seated client operates a foot pedal to move the drive rod between the unlocked and locking positions. When in the locking position, the drive rod prevents a chain or other connecting means of the ankle shackles from moving upwards between the guide socket and the receiver socket.
A back surface of a seat pad is elastically supported by a support member. An air groove that forms an air duct is formed in the back surface of the seat pad. The support member is formed by an airtight sheet-shaped body, and the sheet-shaped body is arranged contacting the back surface of the seat pad so as to form the air duct by closing off an open portion of the air groove.
A linkage that provides a fully flat reclined position is described. The linkage includes a full-flat lift link pivotally coupled to a seat support link. A backrest support link couples to the lift link through an oblong aperture to provide additional range of motion. The lift link includes a laterally extending flange, the perimeter of which acts as a cam surface for a cam pin that obstructs reclining of the backrest support link when the rocker-recliner is in an upright position. When fully reclined, the linkage configures a footrest, seat portion, and backrest portion in a generally equal plane to provide a fully flat seating surface.
A roof assembly for a vehicle roof opening comprises a pair of guide rails extending in a non-parallel way and at a distance from each other. At least one closure element is adjustable in order to at least cover and at least partly open the opening. At least one pair of sliding elements opposite of each other on each of opposite sides of the closure element is provided for slidably engaging in the respective guide rail. The sliding elements are slidably connected to the closure element in a substantially lateral direction. A biasing device is used for biasing the sliding elements relative to the closure element in a substantially lateral direction by being attached to the closure element on one end and being operatively connected to each pair of opposite sliding elements on the other end with interposition of a synchronizing device equalizing the movements of the sliding elements.
The present invention relates to a raisable canopy system for a truck having a rear box with a first wall and a second wall opposite the first wall. A pair of actuator mounts are mounted to the first wall and the second wall, respectively. A canopy mount is connected to the pair of actuator mounts, is disposed adjacent to one end of the box and extends upwards from the box. A canopy substantially extends over top of the box and pivotally connects to the canopy mount. A pair of actuators are pivotally connected to and extend outwards from the pair of actuator mounts, respectively. The pair of actuators each pivotally connect to the canopy. The pair of actuators are configured to selectively move the canopy from a closed position in which the canopy covers and abuts the box to an open position in which the canopy is angularly spaced-apart from the box.
Mechanically or powered activated, retractable, partition-able enclosure-panels with or without custom brackets for any style open-air-vehicle having roof structures, including cars and boats, is taught. The partition-able enclosure panels for a driver's side, passenger's side, or rear opening of an open-air car, each include two or more partition-sections, and a rotatable spindle, where each of the partition-sections is designed to be attached to and detached from an adjacent partition-section, and each of the partition-sections is fixedly or non-fixedly attachable to the rotating spindle, so that when the partitions are attached to each other and the spindle is rotated all partitions are controlled by said rotating spindle and when the partitions are detached from each other, only the fixedly attached partition is controlled by the rotating spindle providing for deployment or un-deployment of either a panel or a partition-section. A roof or roof-support with built-in panel supporting devices is also taught.
A reconfigurable gripping device for securely gripping, lifting, and transporting a work piece is provided. The reconfigurable gripping device may include at least a first finger and a second finger each secured to a base platform with a base support. Each of the respective fingers may have a first link, a second link, and a third link each having a corresponding drive mechanism to individually drive the respective link. The first link drive mechanism and second link drive mechanism are configured to control the grasp and adaptability of each of the respective fingers to place the third link upon a work piece. The third link drive mechanism is configured to drive the third link of each of the respective fingers to apply a clamping force upon the work piece.
The present invention provides a kind of permanent magnetic lifting device, which has: a housing, at the bottom of which is a clamping surface for clamping objects; fixed magnet(s), set in housing relatively fixed to housing; a turnable magnet, set in housing relatively turnable to fixed magnet. When turnable magnet is in the first position relative to fixed magnet, the magnetic force generated by fixed magnet and turnable magnet to clamping surface is zero magnetic force; when turnable magnet is in the third position relative to fixed magnet, the magnetic force generated by fixed magnet and turnable magnet to clamping surface is the maximum magnetic force. The permanent magnetic lifting device also has a positioning mechanism for second position to position the turnable magnet in the second position relative to fixed magnet, fixed magnet and turnable magnet generate trial clamping magnetic force to clamping surface for clamping objects on trial.
An auxiliary handle includes an auxiliary shaft, a joint bracket, and a joint clamp. The auxiliary shaft extends along an auxiliary axis and has two ends. The joint bracket has a bracket axis which is substantially perpendicular to the auxiliary axis, and one end of the auxiliary shaft is rotatably connected to the joint bracket for rotation about the bracket axis. The joint clamp has a joint axis which is substantially perpendicular to the bracket axis, and the joint bracket is rotatably connected to the joint clamp for rotation about the joint axis.
A hand grip has an arm and a leg. The arm and the leg extend through a door outer panel and are supported by a holder member and a frame member in a freely pivotable manner, respectively. By operating the hand grip in the same direction as when a sliding door is opened, the arm is pivoted relative to the holder member retained at an initial position, so that a full close latch mechanism is unlocked. By operating the hand grip in the same direction as when the sliding door is closed, the leg is pivoted relative to the frame member, while the holder member is pivoted relative to the frame member against urging force of a coil spring, so that a full open latch mechanism is unlocked.
A motor vehicle door lock, comprising a locking mechanism (3, 4) and a closing/opening device (5 to 8), containing at least a drive (5) and a lever actuating mechanism (6, 7, 8), wherein the lever actuating mechanism (6, 7, 8) in its engaged position is held by a non-actuated triggering lever (10) and it assumes its disengaged state upon activation of the triggering lever (10).
A device for locking a motor vehicle opening panel, and a latch designed for such a locking device. The opening panel includes an opening mechanism so that it can be moved between a closed position in which the opening panel closes off an opening in the roof of the vehicle, and an open position in which the opening panel at least partially uncovers the opening. The opening mechanism includes at least one link rod, a first end of which is articulated to the vehicle about a first fixed transverse axis and a second end of which is articulated to the mobile opening panel about a second transverse axis. The opening panel is mounted to pivot about a third transverse axis able to move longitudinally with respect to the roof. The locking device includes a latch including a base fixed to the opening panel and including a throat configured to accept a fist striker in the closed position and a second striker in the open position. At least one of the strikers is mounted to move relative to the latch and relative to the vehicle.
A cover is releasably secured to a fitting base. The fitting base includes a bottom and sidewalls with a top edge. The cover includes a top having a latch receiving area, a bottom opposite the top and a sliding latch. The sliding latch is positioned on the latch receiving area of the cover. The sliding latch includes a first end with a finger tab, a main body and a second end with locking feet. In the closed position, the sliding latch secures the cover to the cable fitting base.
An outrigger including a horizontally disposed two-stage outrigger assembly and a vertically disposed two-stage outrigger assembly extending downwardly from the outer end of the horizontally disposed two-stage outrigger assembly.
A top for a vehicle having a roll cage. The top includes a rigid cover, and a flexible cover having a first end and a second end defining a length of the flexible cover therebetween. The first end of the flexible cover is attached to the rigid cover. The second end of the flexible cover has at least one fastener for attaching the second end to the roll cage. The flexible cover has an open configuration and a storage configuration. In the open configuration, the flexible cover extends along the roll cage from the first end attached to the rigid cover to the second end attached to a portion of the roll cage spaced from the rigid cover. In the storage configuration, the entire length of the flexible cover including the second end is removably secured against the rigid cover. Roll cage and top assemblies, and vehicles are also disclosed.
An airbag includes: a base chamber; a left-half airbag inflated on a front-left side of the passenger, wherein a first opening is formed through the left-half airbag at an upper portion thereof; and a right-half airbag inflated on a front-right side of the passenger, wherein a first opening is formed through the right-half airbag at an upper portion thereof. A recess is formed between the left-half airbag and the right-half airbag so as to face the passenger, when the airbag is inflated in front of the passenger. The first openings are communicated with each other. A first seam joining the left-half airbag and the right-half airbag is formed to surround the first openings. The first openings communicated with each other are formed to extend in a vehicle front-rear direction.
A wheelchair includes a chassis, a positioning module, a seat frame, and a seat. The positioning module is mounted to an upper portion of the chassis. The seat frame includes a support member secured to and spanning a seating area of the positioning module and a front frame member secured to a front end of the support member and overhanging a front edge of the seating area of the positioning module, such that the seat frame at least partially straddles the positioning module. The front frame member is connected with and at least partially supports at least one of a side frame member, foot rest, leg rest and arm rest assembled with and supported by the front frame member. The seat is secured to an upper surface of the support member.
According to one embodiment, a vehicle frame, front wheel which is formed of a universal caster, a pair of rear wheels, and a lift-up wheel which is formed of a universal caster and is provided at a lower portion of the rear end part of the vehicle frame such that the lift-up wheel is capable of being elevated between a ground-contact position and a non-ground-contact position by an elevation mechanism, the lift-up wheel being configured such that the lift-up wheel, together with the front wheel, movably supports the vehicle frame in a lowered state of the lift-up wheel at the ground-contact position.
Devices, systems, and methods are disclosed which relate to a stake that is twisted into and out of the ground via an adaptor. The adaptor adapts the stake to a power drill, allowing the power drill to twist the stake into and out of the ground by activating the drill. The adaptor is designed to fit a standard drill chuck at one end. At the other end, the adaptor has a fitting to receive the stake. The fitting is such that the stake and adaptor are axially locked so that the stake and adaptor rotate in unison when the drill is activated. The stake is a wire designed in a coil shape with a pilot. The pilot is fit into the adaptor which axially locks the stake with the adaptor.
Provided is a mechanical sealing device which is simply configured and wherein a rotation ring can be stably held in a specified axial position, and warping of the sealed surfaces can be prevented, thereby making it possible to obtain appropriate sealing characteristics. In a mechanical sealing device, a rotation ring is axially held between a rotation ring locking surface of a sleeve and a rotation ring locking surface of a collar. Furthermore, the sleeve, the rotation ring fixing collar, and the rotation ring are integrated together by means of a baffle knock pin for the rotation ring. Due to the above, whether positive pressure or negative pressure is applied, the rotation ring does not move, nor do the sealed surfaces of the rotation ring become warped. Moreover, assembly can be simply performed only by means of the knock pin.
A thermal bulb seal has a bulb portion and a tab portion that is configured to allow welding or other attachment of the bulb seal to the end surface of an insulating structure. Most preferably, the tab portion comprises an angled portion so allow welding of the bulb seal to another insulating structure.
A target for use as an archery or firearm target constructed of a material which provides self-sealing as the target is being used to thereby make the target capable of repeated use.
A computer readable media and computing device for computing and displaying a path trajectory and an aim point icon for directing a putted golf ball from a starting point on a golf course to a target point based on pre-computed putting data for the putting green is provided. The aim point icon is graphically displayed on a visual representation of the putting green at an aim point distance perpendicular to the left or right of the target location, the aim point distance representing a location on the putting green for properly aiming a putt in order to propel the golf ball from the start position to the desired target location.
Teaching aid math games utilizing a mathematical matrix organized about x and y axises where the game is played by correctly associating numbers with their corresponding stations. The matrix comprises a first string of stations and a second string of stations where the first and second strings have the same number of stations. Each station is associated with a numerical value, and each station on the first string is parallel to a corresponding station on the second string where each corresponding station pair add up to the same numerical value. The display of the matrix provides visual associations for mathematical relationships.
A slide rail includes a fixed rail, an intermediate rail a movable rail, and a first to fourth rollers. Use of three rails makes a total length of the slide rail shorter to provide a compact slide rail. The fixed rail includes a rectangular-shaped first plate and a pair of first bent parts; the intermediate rail includes a rectangular-shaped second plate opposed to the first plate and a pair of second bent parts; and the movable rail includes a rectangular-shaped third plate opposed to the second plate and a pair of third bent parts. Among the bent parts, the third bent parts are bent in a direction opposite that of the first and second bent parts.
An image reader may include a shaft, a roller, a guide, and a first side plate comprising a frame portion having a first frame portion, a pair of second frame portions, and a third frame portion connecting with the pair of second frame portions and a first hole surrounded by the frame portion. A first bearing member may be fitted in the first hole and include a bearing portion contacting the first frame portion. The first bearing member may be configured such that an end of the shaft is rotatably held. An engaged portion may extend from the bearing portion and include an engagement portion engaged with the first side plate. The image reader may further include a second side plate, a second bearing member disposed at the second side plate and configured such that the opposite side of the shaft is rotatably held, and a reading unit.
A sheet processing apparatus which is capable of enhancing productivity in flattening a fold top of a sheet bundle. The sheet processing apparatus has a conveying unit that conveys a folded sheet bundle to a processing position, and a holding unit that holds the sheet bundle conveyed by the conveying unit. When the folded sheet bundle has been conveyed by a predetermined distance after a leading end of the sheet bundle has been detected and before the sheet bundle reaches a processing position, the holding unit starts holding the sheet bundle, and then the conveying units stops conveyance of the sheet bundle.
A loading device which is used in coating processes includes a base, a loading plate, and a reversing assembly. The base includes an outer frame and a ring-shaped inner frame rotatably positioned on the outer frame. The loading plate defines a number of holes for loading components. The reversing assembly connects the inner frame to the loading plate. The reversing assembly includes two reversing motors and two shafts. The reversing motors are opposite to each other and fixed on the inner frame. The reversing shafts are opposite to each other and positioned in a straight line. One end of each reversing shaft is coupled with a corresponding reversing motor, the other end of each reversing shaft is fixed on the loading plate. The reversing shafts are driven by the reversing motors to reverse the loading plate relative to the inner frame.
An arrangement at a vice or chuck, where a jaw insert (22) in the vice or chuck is arranged such that it can be rotated around at least one axis (A) such that a holding surface (23) of the jaw insert, which holding surface is turned to face a second holding surface (26) on a second jaw insert (25), can be displaced by rotation of the jaw insert (22) around the axis (A) from its normal holding position facing the second holding surface (26) to a working position in which the holding surface (23) does not face the second holding surface (26) and in which it can be accessed for working.
A fixing device for fixing a fan includes a fixing plate and a pair of fastening members. The fan includes a sidewall defining a number of fixing holes. The fixing plate defines a vent area and a number of slots located around the vent area. Each fastening member includes a connecting plate, a number of first hooks extending out from a first side of the connecting plate, and a number of second hooks extending out from a second side of the connecting plate opposite to the first hooks. Each first hook is latched into the corresponding slot of the fixing plate, each second hook is latched into the corresponding fixing hole of the fan.
A slide device for vehicle seat in which rollers are arranged at three positions on a lower rail including front and rear portions thereof. Among the rollers, the rollers located at the front and rear portions of the upper rail are pivotally supported by roller shafts and that are prohibited from moving on the upper rail, while the rollers located at the position other than the front and rear portions of the upper rail are pivotally supported by a roller shaft that is allowed to move downward on the upper rail.
A hose reel (10) is supported by a mounting bracket (12) which can be attached on a vertical or horizontal surface and allow for 180 degrees of motion to allow the hose reel (10) to automatically swivel in the direction the hose (14) is being pulled. The bracket mechanism (16) consists of integral mounting bosses (18) on the hose reel enclosures (20), a mounting bracket (12), a tube (22) and a constraint device (24) on the tube (22). The mounting bosses (18) on the hose reel enclosures (20) are designed to orient and constrain the mounting tube (22) to allow for the tube to be installed from either end of the hose reel. The constraining device (24) on the tube (22) locks into an integral opening (26) in the mounting bosses (18) to prevent tube (22) displacement in either direction.
A cup holder includes a case main body defining a housing chamber; a lid member rotatably attached to the case main body between a closed position closing the opening portion and an open position opening the opening portion; a cup retaining member; and a parallel link mechanism connecting the case main body and the cup retaining member. A connecting mechanism connects the lid member and the cup retaining member so as to interconnect together so that the cup retaining member ascends to the ascent position from a descent position, and the cup retaining member descends from the ascent position to the descent position. Stopper abutting portions are provided in the cup retaining member and the lid member to control a downward movement of the cup retaining member.
A substrate-mountable holder system, comprising a base having a hook, a first front surface and a second front surface with a groove therebetween, wherein the groove includes a rearward facing face having a step. The system also includes a second portion for operatively engaging the first portion, the second portion including a tongue component positionable within the groove, wherein the tongue component includes a forward facing face having a step. The base also may include at least one notch extending inward from the rear surface, the notch having a first surface at a first depth relative to a rear surface of the base and a second surface at a second, deeper depth relative to the rear surface, and the cover may have at least one ear for releasably engaging the at least one notch.
According to an embodiment disclosed herein, a gurney flap assembly includes an actuator, and a flexible body attaching to the actuator, the body having a downwardly depending flap for moving into and out of an airstream in a pressure side of a wing, wherein the flexible body flexes in reaction to motion of the actuator. This increases the lift force of the rotor blade, wing or aerofoil blade.
An aerodynamic body with an aerodynamic body surface that creates a contoured surface for a fluid to stream around, with a device to influence the flow of the fluid streaming around the aerodynamic surface. The flow-influencing device includes a passage to link the fluid streaming around the aerodynamic surface with an actuator space of an aspirating and purging device situated in the aerodynamic body, and an indentation that is situated next to the passage, which is formed by a recessed section of the aerodynamic surface on a flow-influencing region within the contoured surface of the aerodynamic surface, so that a boundary wall is configured as part of the recessed surface lying opposite the indentation. The aspirating and purging device can generate a swirl in the flow of the fluid streaming around the aerodynamic surface, the rotational axis of which is directed along the assumed aerodynamic body chord direction.
A deployable and tracked solar array mechanism for restraining and releasing deployable solar panel arrays on a spacecraft is provided. The mechanism comprises a solar array drive mountable to the top side surface of the spacecraft. A solar panel array is pivotally attached to the solar array drive and positionable against the spacecraft. At least one notch is formed in at least one of the side edges of the solar panel array. A frame is slidably mounted to the spacecraft around the solar panel array. At least one tab extends from the frame over the solar panel array and releasably restrains the solar panel array. A spring mechanism urges the frame in a direction generally away from the solar array drive assembly. A release mechanism holds the frame against the force of the spring means wherein upon initiation of deployment, the release mechanism disintegrates allowing the spring means to slidably urge the frame in a general direction away from the solar array drive assembly thereby aligning the at least one notch with the at least one tab and releasing the solar panel array from against the spacecraft.
Fuel in an aircraft fuselage fuel tank is cooled by means of cold air flowing from the exterior of the aircraft to a cooling region inside the aircraft. The cooling region may be (a) located to the exterior of the fuel tank, (b) in thermal communication with the fuel tank and (c) in fluid communication with a region downstream of, and remote from, said cooling region, for example, an exhaust port on the outside of the aircraft. The flow of air may be caused by air entering a ram air intake, into which air passes as a result of the motion of the airborne aircraft relative to the surrounding air.
According to an exemplary embodiment of the invention a fuselage segment of an aircraft fuselage is provided, which aircraft fuselage comprises four different radii of curvature, wherein two radii of curvature comprise center points that are not situated on a vertical symmetry axis of the fuselage segment.
An actuator includes a plurality of cylinder units each including a cylinder and a rod, and is pivotably attached, at a first end thereof, to a control surface. A reaction link is pivotably attached, at a first end thereof, to a fulcrum shaft rotatably supporting the control surface. The reaction link is pivotably attached, at a second end thereof, to a second end of the actuator between the plurality of cylinder units.
An aircraft nacelle comprising a power plant having a pipe with an aerodynamic surface, an air intake having an inside pipe with an aerodynamic surface, and an annular support of at least one measuring device having an aerodynamic surface, wherein the annular support is removably-inserted between the power plant and the air intake. In particular, the annular support is inserted downstream of the air intake and upstream of the power plant in a direction of flow of the stream of air, in such a way as to ensure continuity of the aerodynamic surfaces.
An aircraft having a variable geometry for adapting the flight characteristics to different flight situations includes a fuselage with a pair of wings projecting on both sides of the fuselage in the transverse direction (y), each of which wings has an inner wing section arranged stationarily with respect to the fuselage and an outer wing section adjacent thereto and pivotable about a pivot axis. The pivot axis is oriented in a direction deviating from the longitudinal direction (x) of the aircraft by a maximum of 40°.
A winder for winding a web to produce a rolled product is provided. The winder includes a web transport apparatus that is used for conveying the web. Also included in one exemplary embodiment is a plurality of independent winding modules. The winding modules are independently positioned to independently engage the web as the web is conveyed by the web transport apparatus. The winding modules may be configured to wind the web to form a rolled product by center winding, surface winding, and combinations of center and surface winding. The winding modules are structurally and operationally independent of one another where if one module is disabled, another may still operate to produce the rolled product without shutting down the winder.
A shredder is disclosed. The shredder includes a housing having a throat for receiving at least one article to be shredded, and a shredder mechanism received in the housing and including an electrically powered motor and cutter elements. The shredder mechanism enables the at least one article to be shredded to be fed into the cutter elements. The motor is operable to drive the cutter elements so that the cutter elements shred the articles fed therein. The shredder also includes a detector that is configured to detect a thickness of the at least one article being received by the throat, and a controller that is operable to perform a predetermined operation responsive to the detector detecting that the thickness of the at least one article is at least equal to a predetermined maximum thickness.
An injector for a fluid is provided, in particular for fuel, which has a valve housing, an intake nipple for the fluid disposed at one housing end, a nozzle body disposed at the other housing end, which has a valve seat surrounding a spray-discharge orifice, and a valve chamber disposed upstream therefrom, and a fluid-carrying pipe which extends in the valve housing and connects the valve chamber to the intake nipple. To achieve a connection of the fluid-carrying pipe to the valve chamber that is impervious to high operating pressures and is suitable in terms of production and convenient in terms of assembly, an axial blind hole which has an internal thread and is disposed at a radial offset to the housing axis of the valve housing, is formed in the nozzle body, and a fluid connection us established from the blind hole to the valve chamber. At its pipe end facing away from the intake nipple, the fluid-carrying pipe is screw-fitted in the blind hole and the threaded connection is sealed with respect to the blind hole.
An embodiment of an optoelectronic apparatus for assisting an operator in determining the shooting attitude to give to a hand-held grenade launcher so as to strike a moving target including an electronic processing unit configured so as to: measure the pitch angle and the heading angle of the grenade launcher and the distance of the target when the grenade launcher is moved by the operator during the pointing of the moving target, determine position data indicative of the positions of the moving target, determine a future impact time of the grenade on the target on the basis of position data and of data indicative of the ballistics of the grenade, determine a shooting attitude of the target on the basis of the impact time, measure the pitch angle and heading angle indicating the attitude imparted to the grenade launcher by the operator, compute a pitch difference between the shooting pitch angle and the pitch angle measured and a heading difference between the shooting heading angle and the heading angle measured, communicate to the operator the variation of pitch and/or heading to be given to the grenade launcher so that the pitch and/or heading difference is zero.
The present disclosure generally relates to methods of using active braze techniques on beta-alumina. In some specific embodiments, the present disclosure relates to a method of sealing a portion of beta-alumina electrolyte, insulated collar and metal rings of a sodium-based thermal battery.
A friction stir welding method in which a welding tool rotating around an axis is pressed against a welding target portion of workpieces supported by a backing member so that frictional heat is generated and the friction heat softens the welding target portion. The welding tool is at least partially inserted into the softened welding target portion and stirs the softened welding target portion so that the welding target portion is stir welded in a solid phase state. The friction stir welding method includes detecting a temperature of a temperature measurement point provided in the backing member, and calculating an estimated temperature of the welding tool from the detected temperature of the temperature measurement point, based on a predefined correlation between a temperature of the welding tool and a temperature of the backing member.
A counter-rotating spindle includes a shoulder tool, a pin tool inserted in the shoulder tool, a first motor that is connected with the pin tool and rotates the pin tool, and a second motor that is connected with the shoulder tool and rotates the shoulder tool. The direction and the speed of the rotation for the pin tool may be selected independently from the speed and direction of rotation of the shoulder tool enabling optimization of the friction stir welding process. Counter-rotating the pin tool and the shoulder tool may improve the mixing abilities and efficiency of the pin tool and may prevent the galling effect between the pin tool and the shoulder tool. The counter-rotating spindle may be used, for example, for continuous path friction stir welding and spot welding of aluminum and its alloys, including cast alloys, as well as joining similar and dissimilar alloys.
Connection device of a portable electronic equipment with anchorage device provided with a magnetic support, particularly in the car driver and passenger compartment having ventilation air vents of the type provided with fins. The magnetic base has an attraction seat to house the coupling interface of the coupling plate with the coplanar approaching at least two permanent magnets reciprocally attracted one another, axially magnetized with inverted polarity. The magnetic base joined to the anchorage device has an attraction seat with a concave configuration with spherical cap section. The anchorage device is a clamp including two movable jaws, reciprocally articulated one another at a first end, with a cam-shaped surface relatively to the base of the first end, which insists in correspondence of an adjustment locknut, with respect to which a screw passes through coaxially. The magnetic base with attraction seat is associated with the locknut.
A storage box comprises a housing with open ends and a tray that slides out either open end and up to at least fifty percent or up to at least sixty percent of the length of the tray may slide out either open end. Latch members operable from either open end of the housing selectively hold the tray in a centered position and can be released to allow the tray to slide out a selected end of the housing. Multiple latch member mating members may be associated with the housing for selective engagement by the latch members to latch the tray in multiple extended positions between the centered position and fully retracted positions out either the first or second open ends. Latch engagement members mounted on the doors engage latches connecting the tray to the housing when the doors are shut to prevent the latches from becoming unlatched when the doors are shut.
Embodiments of the present invention relate to a cupped shoulder strap. In general, the cupped shoulder strap may be comprised of a cupped shoulder strap receiving section and a plurality of strap. The cupped shoulder receiving section may have a lateral portion and a medial portion. To form a cupped shape, the lateral portion may be affixed, in a nonparallel orientation, to the medial portion at a superior affixing point that is proximate superior ends of the lateral and medial portions. Further, the lateral portion may be affixed, in a nonparallel orientation, to the medial portion at an inferior affixing point that is proximate inferior ends of the medial and lateral portions.
Disclosed are an air bubble ingress prevention mechanism, a liquid material discharge device provided with the air bubble ingress prevention mechanism, and a liquid material discharge method, with which a constant filled state can be achieved without variations and without requiring any additional equipment when a metering section is filled with liquid material. A discharge device is provided with a metering section which has a flow passage communicating with a nozzle, and a plunger which moves back and forth within the flow passage of the metering section. The discharge device comprises an air bubble ingress prevention mechanism which can be mounted at the end of the metering section on the opposite side to the nozzle, and which includes: a first hole which communicates with the flow passage of the metering section, and within which the plunger moves back and forth; a first sealing member which is provided at the end of the first hole at the nozzle side; a second sealing member which is provided at the end of the first hole at the opposite side to the nozzle; and a second hole which communicates with the side face of the first hole.
A dispensing device for a fluid container, which includes a container cap, a switching nozzle, a securing mechanism and a dispensing compartment. The container cap has apertures, and the switching nozzle has a closing and an opening state. In the closing state the switching nozzle hermetically seals the apertures. An oval skirt is attached to the switching nozzle embracing the container cap, having protrusions for fixing the skirt to the container cap. Pressing the skirt releases the fixing and allows switching to an opening state. A setting mechanism determines the limited volume of the dispensing compartment and secures the volume from undesired variation. An annular portion has clefts and quantity markings. The setting mechanism encompasses the annular portion and has setting bumps bulging proximate to the annular portion, and barrel apertures. Upon mating the setting bumps with a cleft, a marking is exposed through the apertures.
A fluid supplying device of the present invention includes a reservoir, an outer tube, an inner tube disposed in the outer tube, a pressing rod, and a positioning handle. The outer tube disposed in the reservoir and is partially exposed outside the reservoir. The pressing rod is slidably disposed in the inner tube. The positioning handle is pivotably disposed to the reservoir and is able to altervatively abut against the pressing rod to prevent the pressing rod from moving. The reservoir forms a relief hole, and the positioning handle forms a through hole. When the pressing rod is restricted by the positioning handle, the relief hole is deviated from the through hole, and vice versa. Thereby, the present invention can prevent gas-leakage and prevent the pressing rod from bouncing up.
The invention relates to a method, system and dispensing device for assisting a patient in complying with a medical regimen. The system includes an electronic dispensing device to be used by the patient which comprises a device to obtain information about the regimen. A device registers operation of the dispensing device by the patient taking the medicines. A warning device reminds a patient of the regimen. A medicine packing station packs the medicine within a package in portions to be taken according to the regimen. A database stores information about the regimen. A service center is provided to assist when necessary. A communication network is provided for communication between the dispensing device and the service center and/or between the service center and the patient.
The present application provides a merchandiser. The merchandiser may include an ambient compartment with at least one ambient product therein, a temperature controlled compartment with at least one temperature controlled product therein, and a vending module in communication with the temperature controlled compartment such that the vending module dispenses a temperature controlled product in response to an ambient product being placed in the vending module.
Wipe dispenser and collector unit particularly for use in gents' toilets, with a storage cabinet (2) for batches of wipes (24), with an aperture for the bottom wipe (24) located at the center of an angled bottom at an acute angle with the horizontal; the cabinet has a wall-mounting rear cover (3) and a front panel (5) connected to it that can be tilted forward in order to open it, with those two components forming the interior of the closed wipe storage cabinet (2), with a waste container at a specific distance underneath, which also has a wall-mounting rear cover (30), whose storage space, open at the top, is defined by the rear cover (30) and the front unit that can be tilted against it, with the bottom of the front unit connecting to the holes (14) at the bottom of the rear cover (30) with matching bolts (15), which can be released when the unit is tilted forward.
An overcap (14) is provided for a container (10) having a hinge (26) supporting a moveable flap (28) to provide access to the container reservoir. First and second skirts (34, 44) are provided for engaging an upper rim on the container body, with one skirt permitting the mounting of the overcap in two alternate positions. In the first position, only the first skirt (34) engages the upper rim, which allows a removable membrane to be positioned on the upper rim of the container. In the second position, the membrane is removed and both the first and second skirts engage the inner and outer edges of the rim of the container.
A tamper evident container includes a storage element having a flange extending outwardly from a top edge, and a lid having top and outer walls configured to fit over the flange of the storage element with the outer wall extending below a bottom edge of the flange. The outer wall may include an inwardly extending locking indentation engaging the bottom edge of the flange of the storage element to retain the lid on the storage element and prevent it from being removed without permanently deforming at least one of the lid and the storage element, The lid further includes a line of reduced strength extending along a portion of the top wall and/or outer wall to detach a portion of the outer wall and disengage the locking indentation from the flange to allow the lid to be disengaged from the flange without further permanent deformation of the lid or the storage element.
A collapsible container includes a rectangular bottom wall and a plurality of walls pivotally connected to the bottom wall. The plurality of walls include first and second side walls disposed in facing relation and first and second end walls disposed in facing relation. An access door is provided in the first end wall. The access door is pivotable between a closed position and an open position. The first side wall is collapsible from an upstanding position to a collapsed position overlaying the bottom wall, the second side wall is collapsible from an upstanding position to a collapsed position overlaying the collapsed first side wall, and the first and second end walls are collapsible from an upstanding position to a collapsed position overlaying the second side wall.
A manipulator, preferably for the assembly of rotor blades of a wind power installation, has a receiving unit for the receiving of a rotor blade and a connection unit via which the manipulator is connected or connectable to the boom of a crane in a torque-rigid manner so that the position and/or alignment of a rotor blade received in the receiving unit relative to the boom can be fixed by the manipulator.
A display system is provided having at least one C-channel having a pair of inwardly extending lips. A plurality of rails having complementary engagement structures are engaged in the C-channel with the lips engaged with the engagement structures. The rails have support structures for displaying flat goods. One type of rail includes a V-shaped support surface to support a corner of an article to be displayed. The C-channels can also be arranged in pairs with left hand and right hand rails being connected to the respective C-channels. The support surfaces on respective left hand and right hand rails are generally aligned and define a support space.
The disclosure is directed generally a biomass conditioning system and methods for conditioning biomass to remove undesirable material for further processing and applications. In some embodiments, the disclosure includes a biomass conditioning system including a conditioning tank, a water input device, a biomass input device, a containment device, a spillway, and a moving separation device. In some embodiments, methods according to the disclosure include pumping water into a conditioning tank, depositing biomass into the conditioning tank, allowing the biomass to soak in the water and separate into a bark portion and a non-bark portion, allowing the bark portion to float to a water line, containing the bark portion to one side of the conditioning tank, moving the bark portion into a bark storage area, separating the non-bark portion into a biomass portion and a debris portion, and moving the conditioned biomass portion into a storage area.