US08552480B2
In one embodiment, a detector includes an AlzIn(1-x)Sb passivation/etch stop layer, an AlxIn(1-x)Sb absorber layer disposed above the Alzn(1-z)Sb passivation/etch stop layer, and an AlyIn(1-y)Sb passivation layer disposed above the AlxIn(1-x)Sb absorber layer, wherein x
US08552478B2
A method of fabricating a corner transistor is described. An isolation structure is formed in a substrate to define an active region. A treating process is performed to make the substrate in the active region have sharp corners at top edges thereof. The substrate in the active region is covered by a gate dielectric layer. A gate conductor is formed over the gate dielectric layer. A source region and a drain region are formed in the substrate beside the gate conductor.
US08552471B2
There is provided a semiconductor apparatus capable of achieving both a reverse blocking characteristic and a low on-resistance. The semiconductor apparatus includes a first semiconductor layer including a channel layer, a source electrode formed on the first semiconductor layer, a drain electrode formed at a distance from the source electrode on the first semiconductor layer, and a gate electrode formed between the source electrode and the drain electrode on the first semiconductor layer. The drain electrode includes a first drain region where reverse current between the first semiconductor layer and the first drain region is blocked, and a second drain region formed at a greater distance from the gate electrode than the first drain region, where a resistance between the first semiconductor layer and the second drain region is lower than a resistance between the first semiconductor layer and the first drain region.
US08552468B2
A semiconductor layer has a first layer of first conductive type, a second layer of second conductive type, and a third layer. The third layer has a first region of first conductive type, and a second region of second conductive type. A second electrode is in contact with each of the first and second regions. A trench is formed on the semiconductor layer at a surface opposite to its surface facing a first electrode. A gate electrode is embedded in the trench with a gate insulating film interposed therebetween. The gate electrode includes a first portion projecting into the first layer through the first region and the second layer, a second portion projecting into the first layer through the second region and the second layer. The second portion projects into the first layer deeper than a depth in which the first portion projects into the first layer.
US08552467B2
A vertical four-quadrant triac wherein the gate region, arranged on the side of a front surface, includes a U-shaped region of a first conductivity type, the base of the U lying against one side of the structure, the main front surface region of the second conductivity type extending in front of the gate region and being surrounded with portions of the main front surface region of the first conductivity type.
US08552458B2
A light emitting diode includes a thermal conductive substrate having at least one electrical isolation layer configured to provide vertical electrical isolation and a heat transfer path through the substrate from a front side (first side) to a back side (second side) thereof. The light emitting diode includes an anode having a through interconnect, and a cathode having a through interconnect, which are arranged side by side on the substrate. The light emitting diode also includes a LED chip mounted to the substrate between the anode and the cathode. A method for fabricating the light emitting diode includes the steps of providing a thermal conductive substrate having an electrical isolation layer, forming an anode via and a cathode via side by side on a first side of the substrate part way through the substrate, forming an anode through interconnect in the anode via and a cathode through interconnect in the cathode via, thinning the substrate from a second side of the substrate to the anode through interconnect and the cathode through interconnect, and mounting a LED chip to the first side in electrical communication with the cathode through interconnect and the anode through interconnect.
US08552444B2
Light from a semiconductor light-emitting element travels in all directions. Thus, light that travels in the directions other than a lighting direction cannot be used effectively. Means for forming a semiconductor light-emitting element having tilted side surfaces, and forming a reflective layer on the tilted side surfaces has been proposed. However, since the tilted surfaces are formed by an etching method or the like, it takes a long time to form the tilted surfaces, and it is difficult to control the tilted surfaces. As a solution to these problems, semiconductor light-emitting elements are placed on a submount substrate and sealed with a sealant, and then a groove is formed in a portion between adjoining ones of the semiconductor light-emitting elements. The grooves formed are filled with a reflective material, and a light-emitting surface is polished. Then, the submount substrate is divided into individual semiconductor light-emitting devices. Thus, a semiconductor light-emitting device having a reflective layer on its side surfaces can be obtained.
US08552441B2
A method for manufacturing the AlGaInP LED having a vertical structure is provided, including: growing, epitaxially, a buffer layer, an n-type contact layer, an n-type textured layer, a confined layer, an active layer, a p-type confined layer and a p-type window layer in that order on a temporary substrate, to form a texturable epitaxial layer; forming a transparent conducting film with periodicity on the p-type window layer of the epitaxial layer, forming a regulated through-hole on the transparent conducting film, and filling the through-hole with a conducting material; forming a total-reflection metal layer on the transparent conducting film; bonding a permanent substrate with the texturable epitaxial layer via a bonding layer, and bring the total-reflection metal layer into contact with the bonding layer; removing the temporary substrate and the buffer layer; forming an n-type extension electrode on the exposed n-type contact layer; removing the n-type contact layer, and forming a pad on the n-type textured layer; and forming a p-type electrode on a back of the permanent substrate. The transparent multilayered film with periodicity provides a greater reflectivity difference and hence brings better results than the conventional reflector consisting of single-layered, or, non-periodic, transparent films; and light-emitting efficiency is enhanced.
US08552439B2
A light-emitting diode (LED) package including a substrate, an LED chip, a polarizer, and a supporter is provided. The LED chip is disposed on the substrate. The polarizer is disposed above the LED chip. The supporter is disposed on the substrate for supporting the polarizer.
US08552430B2
A thin-film transistor array substrate is disclosed. In one embodiment, the transistor includes a capacitor including a lower electrode disposed on the same layer as an active layer and an upper electrode disposed on the same layer as a gate electrode. The transistor may also include a first insulating layer disposed between the active layer and the gate electrode and between the lower and upper electrodes, the first insulating layer not being disposed on a perimeter of the lower electrode. The transistor may further include a second insulating layer between the first insulating layer and the source and drain electrodes, the second insulating layer not being disposed on perimeters of the upper and lower electrodes.
US08552428B2
A power semiconductor device according to the present invention, which has a termination structure in which a field plate is provided on an insulating film filled in a recessed region formed in a semiconductor substrate and includes a plurality of unit cells connected in parallel, includes: a gate wiring region in which gate wiring electrically connected to each gate electrode of the plurality of unit cells is provided; and a gate pad region electrically connected to the gate wiring region, wherein the gate wiring region is disposed on the insulating film filled in a recessed region formed in the semiconductor substrate.
US08552423B2
An aperture ratio of a semiconductor device is improved. A driver circuit and a pixel are provided over one substrate, and a first thin film transistor in the driver circuit and a second thin film transistor in the pixel each include a gate electrode layer, a gate insulating layer over the gate electrode layer, an oxide semiconductor layer over the gate insulating layer, source and drain electrode layers over the oxide semiconductor layer, and an oxide insulating layer in contact with part of the oxide semiconductor layer over the gate insulating layer, the oxide semiconductor layer, and the source and drain electrode layers. The gate electrode layer, the gate insulating layer, the oxide semiconductor layer, the source and drain electrode layers, and the oxide insulating layer of the second thin film transistor each have a light-transmitting property.
US08552422B2
An electronic device is presented, such as a thin film transistor. The device comprises a patterned electrically-conductive layer associated with an active element of the electronic device. The electrically-conductive layer has a pattern defining an array of spaced-apart electrically conductive regions. This technique allows for increasing an electric current through the device.
US08552418B2
The present invention provides a semiconductor device which is not easily damaged by external local pressure. The present invention further provides a method for manufacturing a highly-reliable semiconductor device, which is not destructed by external local pressure, with a high yield. A structure body, in which high-strength fiber of an organic compound or an inorganic compound is impregnated with an organic resin, is provided over an element layer having a semiconductor element formed using a non-single crystal semiconductor layer, and heating and pressure bonding are performed, whereby a semiconductor device is manufactured, to which the element layer and the structure body in which the high-strength fiber of an organic compound or an inorganic compound is impregnated with the organic resin are firmly fixed together.
US08552413B2
Embodiments of the invention generally include a method of forming a nonvolatile memory device that contains a resistive switching memory element that has an improved device switching performance and lifetime, due to the addition of a current limiting component disposed therein. In one embodiment, the current limiting component comprises a resistive material that is configured to improve the switching performance and lifetime of the resistive switching memory element. The electrical properties of the current limiting layer are configured to lower the current flow through the variable resistance layer during the logic state programming steps (i.e., “set” and “reset” steps) by adding a fixed series resistance in the resistive switching memory element found in the nonvolatile memory device. In one embodiment, the current limiting component comprises a tunnel nitride that is a current limiting material that is disposed within a resistive switching memory element in a nonvolatile resistive switching memory device.
US08552404B2
In an ion implantation method, ion implantation into a substrate is performed while changing a relative positional relation between an ion beam and the substrate. A first ion implantation process in which a uniform dose amount distribution is formed within the substrate and a second ion implantation process in which a non-uniform dose amount distribution is formed within the substrate are performed in a predetermined order. Moreover, a cross-sectional size of an ion beam irradiated on the substrate during the second ion implantation process is set smaller than a cross-sectional size of an ion beam irradiated on the substrate during the first ion implantation process.
US08552402B2
A nano-scale resolution fluorescence microscopy system and a method of obtaining an image using the nano-scale resolution microscopy system, and more particularly, a method and a microscopy system, capable of observing fluorescence probes in high resolution by radiating an irregular diffused light to have an incoherent speckle pattern that has low correlation in an adjacent space are disclosed. According to embodiments of the present invention, a diffraction limit of a fluorescence microscope may be overcome, and a super high resolution image on a nanometer scale may be obtained.
US08552396B2
A ground-based system that provides quasi real-time measurement and collection of snow-water equivalent (SWE) data in remote settings is provided. The disclosed invention is significantly less expensive and easier to deploy than current methods and less susceptible to terrain and snow bridging effects. Embodiments of the invention include remote data recovery solutions. Compared to current infrastructure using existing SWE technology, the disclosed invention allows more SWE sites to be installed for similar cost and effort, in a greater variety of terrain; thus, enabling data collection at improved spatial resolutions. The invention integrates a novel computational architecture with new sensor technologies. The invention's computational architecture is based on wireless sensor networks, comprised of programmable, low-cost, low-powered nodes capable of sophisticated sensor control and remote data communication. The invention also includes measuring attenuation of electromagnetic radiation, an approach that is immune to snow bridging and significantly reduces sensor footprints.
US08552387B2
In an embodiment, an initial segmentation of an examination object is fixed, wherein an attenuation coefficient is assigned to each segment of the segmentation. Raw radiation data about the examination object arranged in the positron emission tomography scanner is acquired, and a correction factor is determined for each pixel with the aid of an optimization method, in which the probability of the acquired raw radiation data is maximized taking into account the segmentation and the attenuation coefficients assigned to the segments. A statistical parameter of the correction factors is determined for each segment and the segmentation is corrected by subdividing a segment as a function of the statistical parameter determined for the segment. A segment correction factor is determined for each segment from the correction factors assigned to the segment and the attenuation coefficients assigned to the segments are corrected as a function of the segment correction factors.
US08552383B2
Methods for in-vitro analysis of biological cells and/or microorganisms to determine characteristics such as: degree of differentiation, cell type, donor individuals, culture conditions, purity, lack of natural characteristic, or additional characteristics in comparison to natural characteristics. The methods include the steps of: (a) projecting infrared radiation on a sample; (b) recording spectral characteristics of the sample; (c) deriving a Fourier transform infrared spectrum (FT-IR) from the collected spectral characteristics; (d) generating a derivative transformation of the FT-IR spectrum; (e) comparing said derivative transformation with a derivative of a reference FT-IR spectrum; (f) identifying deviations of said derivative from said reference derivative; and (g) providing an analysis of said characteristics based on the presence of said deviations. In addition, the invention relates to an apparatus for carrying out the disclosed methods.
US08552382B2
A method of determining a physical property of a composite material includes providing a series of composite materials/surfacing films, which are subjected to increasing thermal experience to create a set of thermal effect standards, collecting mid-IR spectra on those standards, performing data pre-processing and then multivariate calibration on the spectra of the composite materials/surfacing films, and using that calibration to predict the thermal effect for samples in question.
US08552381B2
An infrared (IR) scene projector device includes a light emitter and a thermal emitter. The light emitter is configured to selectably provide visible light. The thermal emitter includes a vertically aligned carbon nanotube (VACN) array. The VACN array includes a plurality of carbon nanotubes disposed proximate to a thermally conductive substrate, such that a longitudinal axis of the carbon nanotubes extends substantially perpendicular to a surface of the substrate. The thermal emitter absorbs the visible light from the light emitter and converts the visible light from the light emitter into IR radiation.
US08552380B1
An IR detector in the form of a thermopile including one or more thermocouples on a dielectric membrane supported by a silicon substrate. Each thermocouple is composed of two materials, at least one of which is p-doped or n-doped single crystal silicon. The device is formed in an SOI process. The device is advantageous as the use of single crystal silicon reduces the noise in the output signal, allows higher reproducibility of the geometrical and physical properties of the layer and in addition, the use of an SOI process allows a temperature sensor, as well as circuitry to be fabricated on the same chip. The detector can also have an IR filter wafer bonded onto it and/or have arrays of thermopiles to increase the sensitivity. The devices can also be integrated with an IR source on the same silicon chip and packaged to form a complete and miniaturised NDIR sensor.
US08552377B2
This invention provides a design to process a large range of detection beam current at low noise with a single detector. With such a design, the detection system can generate up to 1010 gain and maximum signal output at more than mini Ampere (mA) level. A condenser lens is configured to increase bandwidth of the detector that scan speed can be enhanced.
US08552371B2
There is provided a method for setting a suitable imaging magnification for each of a plurality of measurement places in a charged particle beam apparatus which images a semiconductor pattern.For a given measuring point coordinate, a line segment or a vertex representing a change in concavity and convexity near the measuring point coordinate is searched, and an imaging magnification is set so that coordinates on a sample corresponding to both ends which gives a length that serves as a reference falls in a field of view of the charged particle beam apparatus by letting a minimum distance be the reference, of distances between line segments representing a change in concavity and convexity from the measuring point coordinate or a distance between neighboring vertexes.
US08552368B1
A low pressure ionization source and method for detecting trace atmospheric gases with an instrument employing ionized target substances. The ionization source and method may employ electric potential ionization, photoionization, and/or ionization by alpha and/or beta particle irradiation. In one embodiment, an ionization source includes a fixture securable to the instrument, a chamber within the fixture, two sample entrance passageways into the chamber, an electrode receiver hole, a lamp receiver hole, and an ionized sample exit hole from the chamber. A gas sample entering the chamber via a sample entrance passageway is ionized by one of an electric potential induced by an electrode received in the electrode receiver hole or a light beam provided by a photoionization lamp received in the lamp receiver hole. At least a portion of the ionized gas sample exits the chamber via the sample exit hole to a detector/analyzer of the instrument.
US08552367B2
A micro-reflectron for a time-of-flight mass spectrometer including a substrate and integrated with the volume of the substrate, means for application of a potential gradient in a volume suitable for constituting a flight zone of the ions. The means of application includes at least two polarization electrodes and a wall of at least one resistive material that can be polarized between these electrodes so as to generate a continuous potential gradient, itself providing the function of reflectron, this flight zone, these electrodes and this wall being obtained by the technology of microelectromechanical systems (MEMS) and this micro-reflectron having a thickness of less than 5 millimeters while its other dimensions are less than 10 times this thickness.
US08552365B2
Methods for operating a mass spectrometer having at least one component having mass-dependent transmission, comprising: injecting a first sample of ions having a first mass range into an ion accumulator for a first injection time under first operating conditions suitable for optimizing transmission of ions of the first range; acquiring a full-scan mass spectrum of the first sample of ions; selecting ion species having a second mass range different than the first range; calculating a second injection time, the second injection time suitable for injecting a population of the selected ion species into the ion accumulator under second operating conditions suitable for optimizing transmission of ions of the second range; injecting a second sample of ions having the selected ion species into the ion accumulator for the second injection time under the second operating conditions; and acquiring a mass spectrum of ions derived from the selected ion species.
US08552364B2
Methods for proteomic analysis are provided. For example, in one aspect a method for identifying and sequencing a peptide may include fractionating a biological sample containing a peptide of interest to at least partially isolate the peptide, obtaining mass spectra of the peptide, and accelerating the peptide into a collision chamber at a plurality of discrete collision energies for a discrete period of time to form a plurality of peptide fragments for each of the plurality of discrete collision energies. The method may further include obtaining a plurality of fragmentation mass spectra from the plurality of peptide fragments for each of the plurality of discrete collision energies, summing the plurality of fragmentation mass spectra from each of the plurality of discrete collision energies to form a plurality of discrete collision energy mass spectra, one discrete collision energy mass spectra from each discrete collision energy, summing the plurality of discrete collision energy mass spectra to form a final mass spectrum for the peptide fragments, and identifying a sequence of amino acids corresponding to the peptide from the final mass spectrum.
US08552359B2
An apparatus for concentrating light and associated method of use is disclosed. This apparatus includes a first outer wall having an anterior end, a posterior end, an inner surface and an outer surface, the inner surface defining an interior portion, the interior portion having an anterior end and a posterior end, and a light source disposed within the interior portion. The first outer wall has an opening in the posterior end, the opening having an opening diameter. The interior portion has a substantially frusto-conical shape and has a cross-sectional diameter at the opening equal to the opening diameter and a second cross-sectional diameter near the anterior end that is less than the opening diameter and the inner surface is photo-reflective. The light passes through a sample through an aperture and a collector lens or a second outer wall. A transmission diffraction grating may be utilized.
US08552348B2
A collapsible field director includes at least one master vane and at least first and second slave vanes. The master vane includes a conductive flap that is articulably attached to a mounting flange. The flange is attached to a planar support member having openings or slots formed therein. Each slave vane has a mounting tab thereon. The slave vanes are flexibly connected to the master vane. The slave vanes are flexibly displaceable with respect to the conductor flap and the conductor flap is articulably movable with respect to the mounting flange so that the field director structure, in the deployed state, occupies a self-supported disposition in which the conductor flap is oriented perpendicular to the mounting flange and the slave vanes are angularly spaced from the master vane with the tabs on the slave banes being received in openings or slots in the planar member.
US08552347B2
A method and a device (1) for bonding a metal fairing (6) to protect a leading edge of an aircraft airfoil (7), the metal fairing (6) is designed to be bonded against the airfoil (7) with the help of an adhesive (9). The bonding device (1) is remarkable in that it includes a rigid yoke (2) having inserted therein induction heater elements (30) for heating the metal fairing (6).
US08552345B2
The invention relates to a method for operating a diesel fuel filter heater comprising at least one PTC element, in a motor vehicle. According to the invention, a glow plug control device is used to generate an effective voltage from a vehicle system voltage using pulse width modulation, which is then applied at the filter heater.
US08552342B2
To provide a heater that can reduce fixing failure in a paper passing area while suppressing a temperature rise in a sheet non-passing area, and a fixing apparatus including the heater.Resistors are connected in parallel between two conductive patterns that are provided on a heater substrate along the longitudinal direction of the substrate, and resistors are arranged so that the shortest current path of each of the resistors can overlap the shortest current path of an adjacent resistor in the longitudinal direction of the substrate.
US08552341B2
A welding torch comprising: a main cylindrical conductive assembly with a front diffuser section having a plurality of circumferentially spaced shielding gas diffuser orifices for directing shielding gas radially outwardly from the assembly, a forwardly facing threaded bore extending through a cylindrical support nose and an elongated wire passageway coaxial with the threaded bore and opening at the rear end of the assembly. An insulated, cylindrical protective sleeve fitted around both the support nose and the diffuser orifices where the sleeve has a front clearance opening and circumferentially spaced openings communicated with the diffuser orifices and a contact tip having a central wire guide bore with a diameter only slightly larger than the diameter of the welding wire, a threaded rear body, a front extension passing through the front clearance opening and a radially extending flange between the rear body and the front extension to hold the protective sleeve around the nose when the body is screwed into the threaded bore of the main assembly.
US08552335B2
A plasma jet apparatus for performing plasma processing of an article includes: an elongated central electrode (2,15), an elongated cylindrical outer electrode (1) or two outer electrodes (15,16) surrounding the central electrode and being coaxial with the central electrode, or two electrodes substantially parallel to the central electrode. an electrical insulator (3) or insulators (18,19) are disposed between the outer electrode(s) and the central electrode, wherein a discharge lumen having a distal end and a proximal end is defined between the central electrode and the electrical insulator(s). A supply opening (6) is disposed at the distal end of the discharge lumen for supplying a plasma producing gas to the discharge lumen, A power source (9) provides a voltage between the central electrode and said outer electrode. The electrical insulator has a radial or outward extension (40,20) at the proximal end beyond the outer surface of the outer electrode(s).
US08552334B2
A plasma processing chamber includes a cantilever assembly and at least one vacuum isolation member configured to neutralize atmospheric load. The chamber includes a wall surrounding an interior region and having an opening formed therein. A cantilever assembly includes a substrate support for supporting a substrate within the chamber. The cantilever assembly extends through the opening such that a portion is located outside the chamber. The chamber includes an actuation mechanism operative to move the cantilever assembly relative to the wall.
US08552333B2
A circuit protection device includes a plasma gun configured to generate a plasma plume, at least one capacitor configured to store electrical energy, and a trigger circuit communicatively coupled to the plasma gun and the capacitor. The trigger circuit is configured to transmit a first signal to the capacitor to cause the capacitor to transmit a first portion of the electrical energy to the plasma gun. The trigger circuit is also configured to transmit a second signal to the plasma gun to cause the plasma gun to generate the plasma plume using the first portion of the electrical energy.
US08552332B2
Provided are a bolt for projection welding and a method of welding the same in which a portion of large fusion depth is formed in a small region and in which junction to a steel sheet part is secured in other regions, thereby realizing high weld strength and stable junction state. A bolt includes a shaft part, an enlarged diameter part, and a fusion bonding projection, the fusion bonding projection including an initial fusion part having at an end surface thereof a tapered portion and a main fusion part continuous with the initial fusion part. Energization with welding current for fusing the fusion bonding projection only is effected on the fusion bonding projection, and in which through pressurization of the fusion bonding projection against a steel sheet part and subsequent energization thereof, a region of the fusion bonding projection is fusion-bonded to the steel sheet part, and an end surface of the enlarged diameter part on the outer peripheral side thereof is brought into junction with a surface of the steel sheet part. With this structure, it is possible to realize a satisfactory welding in an appropriate fused state.
US08552330B2
A submerged arc welding system includes a robot having a first arm connected to a second arm, and at least one wire supply. A welding torch is connected to a first end of the second arm of the robot. A wire motor is mounted to a second end of the second arm of the robot. The wire motor moves wire from the wire supply along a wire path to the welding torch. The system further includes a flux supply and a flux delivery system configured to move flux from the flux supply along a flux path to the welding torch.
US08552329B2
A submerged arc welding system. In one embodiment, the submerged arc welding system includes a robot, a flux supply distal from the robot, and at least one wire supply distal from the robot. The system also includes a welding torch connected to the robot, a wire path connecting the wire supply to the welding torch, and a flux path connecting the flux supply to the welding torch. A flux delivery system is configured to move flux from the flux supply to the welding torch. At least one vent is disposed on the flux path adjacent the welding torch, to evacuate air from the flux path.
US08552325B2
A click mechanism for an electric part comprises a spring 50 made of a plate material and disposed on a rotatable plate 40 that rotates integrally with a rotationally-manipulated shaft of an electric part, a click piece 60 disposed on the outer perimeter of the rotatable plate 40 so as to retractably protrude from the outer perimeter, and projections and depressions 25 formed on the inner perimeter of a housing 22 for the rotatable plate 40 to be arranged in the circumferential direction of the inner perimeter. The click piece 60 is cylindrical and biased by the spring 50 to be in resilient contact with the projections and depressions 25 at the perimeter thereof. The click mechanism can produce a fine and clear click feel, has high durability, and can be reduced in size.
US08552320B2
A switch for generating short-term supply-line interruptions during switching-on with contact elements (1, 2, 3, 5, 6, 21, 22, 23) and an actuating element (4) for opening and closing electrical contacts between the contact elements, wherein (1, 2, 3, 5, 6, 21, 22, 23). A first contact element (1, 5, 21) is mounted elastically and, when a contact is closed via the first contact element (1, 5, 21), can be deflected elastically in such a way that the contact, after initial closing, is opened again by the elastic deflection.
US08552318B2
Rotary switch interlock mechanisms and electrical switch assemblies with a rotary switch interlock mechanism are presented herein. An electrical distribution device with at least two electrical switches is disclosed. Each of the electrical switches has a switch actuator that is movable between engaged and disengaged positions. A rotary interlock member is rotatably mounted to the housing of the electrical distribution device adjacent the first and second electrical switches. The rotary interlock member is rotatable 180 degrees between a first orientation, whereat the rotary member allows the switch actuator of the second electrical switch into its engaged position while preventing the switch actuator of the first electrical switch from being moved into its engaged position, and a second orientation, whereat the rotary member allows the first switch actuator to be moved into its engaged position while preventing the second switch actuator from being moved into its engaged position.
US08552315B2
A capacitive position sensor is provided having a touch-sensitive area defined by a single-layer of electrodes arranged in a pattern along two axes. The electrode pattern includes a plurality of units each occupying a portion of the touch sensitive area along one axis. Each unit has at least three lines of elongate electrodes spaced apart in the one axis and extending for a length parallel to the other axis. The three lines of elongate electrodes in each unit comprise at least one line of drive electrodes and two lines of sense electrodes or at least one line of sense electrodes and two lines of drive electrodes. Selected electrodes of each unit are arranged in interconnected groups, each group having electrodes from more than one line which have partially overlapping extents along their length.
US08552295B2
A cable assembly has a clamp provided at an end of a multi-core cable. The clamp, which is formed such that the inner diameter thereof increases as it is closer to the rear end, is fixed by caulking to the outer circumference of a sheath. An inner spring and an outer spring are arranged around the outer circumference of a sheath. The inner spring is fixed to the clamp in such a manner as the end thereof on the cable tip side is sandwiched between the sheath and the inner surface of the clamp. The outer spring is shorter than the inner spring in the cable axial direction, and the end thereof on the cable tip side is fixed to the outer circumference of the clamp. The outer circumference of the inner spring and the outer spring is covered with a rubber boot.
US08552291B2
A cable for high speed data communications that includes a first inner conductor enclosed by a first dielectric layer and a second inner conductor enclosed by a second dielectric layer. The inner conductors and the dielectric layers are disposed within the cable in parallel with a longitudinal axis of the cable. The cable also includes drain conductors disposed within the cable laterally to the inner conductors adjacent to the dielectric layers along the longitudinal axis of the cable and within thirty degrees of a horizontal axis through the inner conductors. The cable also includes a conductive shield composed of a strip of conductive shield material wrapped in a rotational direction along and about the longitudinal axis around the inner conductors, the dielectric layers, and the drain conductors.
US08552287B2
A stacked-layered thin film solar cell has a plurality of independent unit cells comprising a substrate, a first electrode layer, a first photoconductive layer, an interlayer, a second photoconductive layer, and a second electrode layer in a series stacked structure, wherein at least one first separation groove is formed within the first electrode layer and the stacked-layered thin film solar cell is characterized in: at least one second separation groove formed on the interlayer, at least one connection groove passing through the first photoconductive layer and the second photoconductive layer, and at least one third separation groove extending downward at a periphery of each of the unit cells so that the connection grooves and the third separation groove are concurrently located inside a projection zone of the second separation groove.
US08552284B2
A pipe-shaped thermoelectric power generating device includes an internal through-hole along the axis direction of the pipe-shaped thermoelectric power generation device; a plurality of first cup-shaped components each made of metal; a plurality of second cup-shaped components each made of thermoelectric material; a first electrode; a second electrode. The plurality of first cup-shaped components and the plurality of second cup-shaped components are arranged alternately and repeatedly along the axis direction. The first electrode and the second electrode are provided respectively at one end and at the other end of the pipe-shaped thermoelectric power generation device.
US08552276B1
A novel maize variety designated X90B043 and seed, plants and plant parts thereof, produced by crossing Pioneer Hi-Bred International, Inc. proprietary inbred maize varieties. Methods for producing a maize plant that comprises crossing hybrid maize variety X90B043 with another maize plant. Methods for producing a maize plant containing in its genetic material one or more traits introgressed into X90B043 through backcross conversion and/or transformation, and to the maize seed, plant and plant part produced thereby. This invention relates to the maize variety X90B043, the seed, the plant produced from the seed, and variants, mutants, and minor modifications of maize variety X90B043. This invention further relates to methods for producing maize varieties derived from maize variety X90B043.
US08552269B2
A soybean cultivar designated 94L41 is disclosed. The invention relates to the seeds of soybean cultivar 94L41, to the plants of soybean cultivar 94L41, to the plant parts of soybean cultivar 94L41, and to methods for producing progeny of soybean cultivar 94L41. The invention also relates to methods for producing a soybean plant containing in its genetic material one or more transgenes and to the transgenic soybean plants and plant parts produced by those methods. The invention also relates to soybean cultivars or breeding cultivars, and plant parts derived from soybean cultivar 94L41. The invention also relates to methods for producing other soybean cultivars, lines, or plant parts derived from soybean cultivar 94L41, and to the soybean plants, varieties, and their parts derived from use of those methods. The invention further relates to hybrid soybean seeds, plants, and plant parts produced by crossing cultivar 94L41 with another soybean cultivar.
US08552261B2
A soybean cultivar designated S090057 is disclosed. The invention relates to the seeds of soybean cultivar S090057, to the plants of soybean S090057, to plant parts of soybean cultivar S090057, and to methods for producing a soybean plant produced by crossing soybean cultivar S090057 with itself or with another soybean variety. The invention also relates to methods for producing a soybean plant containing in its genetic material one or more transgenes and to the transgenic soybean plants and plant parts produced by those methods. This invention also relates to soybean cultivars, or breeding cultivars, and plant parts derived from soybean variety S090057, to methods for producing other soybean cultivars, lines or plant parts derived from soybean cultivar S090057, and to the soybean plants, varieties, and their parts derived from use of those methods. The invention further relates to hybrid soybean seeds, plants, and plant parts produced by crossing the cultivar S090057 with another soybean cultivar.
US08552256B2
The present inventors identified a novel rice glutelin gene, GluD-1, which is expressed specifically in seeds. The promoter of the GluD-1 gene was confirmed to induce seed-specific gene expression, and to induce expression of downstream genes specifically in the endosperm during the early stage of seed maturation process. More specifically, the GluD-1 promoter can induce strong expression of an exogenous gene in sites including the endosperm.
US08552253B2
Provided is a method of using any mammal except humans, in particular, a mammal as an attention deficit hyperactivity disorder model, wherein genes of G protein-coupled receptor kinase interacting protein 1 (GIT1) as a neuronal synapse protein in the brain are knocked out from the mammal. In addition, disclosed is analysis of GIT1 knock-out mice in aspects of molecular biology, cellular biology, electrical biology and animal behavior and, more particularly, a screening method of novel drug, wherein excessive behavior as an attention deficit hyperactive disorder as well as recovery of theta wave in the frontal lobe are observed by administering a candidate material of the drug, thereby inducing recovery of the attention deficit hyperactivity disorder.
US08552250B2
An absorbent article comprises a first location of a first portion of a visual fullness indicating area that is configured to change to a subsequent visual state when indicating the presence of a bodily exudate. At the first location, the first portion has a first overall width. The absorbent article also comprises a second location of a second portion of a visual fullness indicating area that is configured to change to a subsequent visual state when indicating the presence of a bodily exudate. The second location is outboard from the first location. The second location has a second overall width that is wider than the first overall width.
US08552236B2
A catalyst for the conversion of methane to higher hydrocarbons including aromatic hydrocarbons comprises particles of a porous refractory material, crystals of a zeolite material grown within the pores of the refractory material, and at least one catalytically active metal or metal compound associated with the zeolite crystals.
US08552235B2
A process for hydrodeoxygenation of feeds derived from renewable sources with conversion by decarboxylation/decarbonylation limited to at most 10%, using a bulk or supported catalyst comprising an active phase constituted by at least one element from group VIB and at least one element from group VIII, said elements being in the sulphide form, and the atomic ratio of the metal (or metals) from group VIII to the metal (or metals) from group VIB being strictly more than 0 and less than 0.095, said process being carried out at a temperature in the range 120° C. to 450° C., at a pressure in the range 1 MPa to 10 MPa, at an hourly space velocity in the range 0.1 h−1 to 10 h−1, and in the presence of a total quantity of hydrogen mixed with the feed such that the hydrogen/feed ratio is in the range 50 to 3000 Nm3 of hydrogen/m3 of feed.
US08552232B2
The present invention provides fully renewable turbine and diesel fuels created from biomass sources. In one embodiment, the fully renewable turbine fuel is comprised of mesitylene and at least one alkane. Preferably, the turbine fuel comprises from about 50 to 99 wt % mesitylene and from about 1 to 50 wt % of at least one alkane. In another embodiment the diesel fuel comprises mesitylene, octadecane, and optionally octane or nonane. Preferably, the diesel fuel comprises from about 50 to 99 wt % mesitylene, and from about 1 to 50 wt % octadecane. These biomass derived fuels may be formulated to have a wide range of cetane values and differing freezing and boiling points. A preferred biogenic turbine fuel comprises one or more synthetic paraffinic kerosenes (SPK) and/or hydroprocessed renewable jet (HRJ) fuel; and between about 8 to 25 vol % of mesitylene. Another preferred biogenic turbine fuel is a blend of about 50% petroleum-based fuel; and about 50% of one or more of synthetic paraffinic kerosenes (SPK) and/or hydroprocessed renewable jet fuel (HRJ), and mesitylene.
US08552227B2
A dehydrofluorination process is disclosed for making hydrofluoroolefins of the structure RfCH═CHRf, wherein each Rf is independently a perfluoroalkyl group or a perfluoroalkyl group having a terminal hydrogen. The process involves reacting RfCH2CHFRf with a basic aqueous solution to produce a product mixture comprising RfCH═CHRf.
US08552223B2
A method of making a heterogeneous catalyst, the catalyst produced therefrom, and the use of the catalyst, comprising mixing a dried ion exchange resin with a solution of a ketone and a metal, swelling the ion exchange resin, distributing the metal in the resin, and transforming without reducing agents the metal to zero valent at a temperature below 120° C.
US08552220B2
To develop a highly safe measure to treat Alzheimer's disease using a secretase-inhibiting substance, there is provided a compound represented by the following general formula (I) or a salt thereof: wherein A represents a phenyl group or the like, R1 represents a chlorine atom, a bromine atom, or a nitro group or the like, R2, R3, R4, and R5 each represent a hydrogen atom or the like, and L represents CH2—CH2 or CH═CH.
US08552216B2
Process for the production of methyl acetate by carbonylating a dimethyl ether feed with carbon monoxide under substantially anhydrous conditions, in the presence of a zeolite catalyst effective for the carbonylation. The carbonylation is carried out at a temperature in the range of 275 to 350° C. and in the presence of hydrogen.
US08552208B2
Tetramic acid analogues of Formula I and Formula II have antibacterial activity, primarily against gram-positive bacteria, and are iron chelators.
US08552198B2
A novel crystal of (R)-2-[[[3-methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl]methyl]sulfinyl]-1H-benzimidazole or a salt thereof of the present invention is useful for an excellent antiulcer agent.
US08552182B2
A method for producing a 3-(substituted oxy)-4-pyridazinol compound represented by the following general formula (I): comprising reacting a compound represented by the following general formula (III): with a compound represented by the following general formula (IV): MO—R2 (IV). The compound represented by the general formula (I) can be reacted with a compound represented by the following general formula (VI): to provide a compound of general formula (V): Each of the groups in the formulas is defined. The compounds of general formulas (I) and (V) can be obtained in a high yield and with high selectivity at a low cost, and therefore various functional and active substances can be advantageously synthesized using the compounds as a medicine, an agricultural chemical, a functional material, or an intermediate thereof.
US08552173B2
The present invention relates to compositions useful as probes and in other applications and methods of their use. In some embodiments, nucleotides are prepared and functionalized with dyes. In some embodiments a first molecule is functionalized with an alkynyl group, a second molecule is functionalized with an azide group, and said first and second molecules are mixed under conditions to form a conjugate with a 1,2,3-triazol group. In further embodiments, a nucleotide is functionalized with an alkynyl group, a dye is functionalized with an azide group, and mixing the nucleotide and the dye forms a conjugate capable of emitting light.
US08552172B2
Molecules are provided for inducing or facilitating exon skipping in forming spliced mRNA products from pre-mRNA molecules in cells. The molecules may be provided directly as oligonucleotides or expression products of vectors that are administered to a subject. High rates of skipping can be achieved. High rates of skipping reduce the severity of a disease like Duchene Muscular Dystrophy so that the disease is more like Becker Muscular Dystrophy. This is a severe reduction in symptom severity and mortality.
US08552159B2
Provided herein are carbohydrate complement-modified bifunctional glycoproteins, and their use in tumor-selective therapy. The bifunctional glycoproteins comprise a first component that specifically binds to a tumor-specific antigen and a second component having enzymatic activity by means of which a non-toxic prodrug is cleaved into a cytotoxic drug. The carbohydrate complement comprises at least one exposed carbohydrate residue selected from the group consisting of mannose, galactose, N-acetylglucosamine, N-acetyllactose, glucose and fucose. The modified carbohydrate complement contributes to increased relative concentration of the glycoproteins at the site of the tumor, and enhanced clearance from the general circulation and non-tumor sites.
US08552139B2
The present invention relates to biodegradable polymers (e.g., polyesters and polyester amides) derived from functionalized biologically active compounds that can provide site specific delivery of bioactive compounds upon biodegradation in a controlled manner.
US08552134B2
A method of producing a water-absorbent resin of the present invention reduces amounts of a residual cross-linking agent and a residual surfactant, achieves high productivity, and improves physical properties of the resultant water-absorbent, such as absorption capacity, extractable polymer content, powder friction, and gel crushability. The method includes the steps of: polymerizing an aqueous monomer solution containing as a major component an acrylic acid monomer in the presence of a cross-linking agent; and drying the resultant polymer by heating, in which the cross-linking agent is a multifunctional (meth)acrylate cross-linking agent having polyethylene glycol structural units including a total of 6 to 200 ethylene oxide repeating units, and the aqueous monomer solution includes a mono(meth)acrylate compound having polyethylene glycol structural units in an amount of 0.1 to 30% by weight relative to an amount of the multifunctional (meth)acrylate cross-linking agent.
US08552131B1
Disclosed is a substantially alternating copolymer that is conformal, hard, flexible, and has low oxygen permeability. Also disclosed is an iCVD-based method of coating a substrate with the substantially alternating copolymer.
US08552126B2
The present invention relates to an aqueous polymer dispersion whose dispersed addition polymer P comprises, copolymerized in free-radically polymerized form, at least one polar monomer having a water solubility of greater than 50 g/liter (measured at 20° C.), and obtainable by free-radically initiated aqueous emulsion polymerization, the polar monomer being metered to the reaction mixture during the polymerization process at a variable, i.e., nonconstant rate, for example in the sense of a rate gradient. The present invention further relates to processes for preparing these aqueous polymer dispersions, to their use as binders and/or in coatings, and also to coatings comprising the polymer dispersion of the invention.
US08552123B2
A thermosetting resin including at least one repeating unit represented by the following Chemical Formula 1: wherein, in Chemical Formula 1, A is derived from a phenolic moiety, an anilinic moiety, or a combination thereof, L is C(O)O, C(O)NR′ wherein R′ is hydrogen, a substituted or unsubstituted C1 to C20 alkyl group, a substituted or unsubstituted C6 to C30 aryl group, or a substituted or unsubstituted C6 to C30 aryloxy group, an aromatic ester, an aromatic ester-imide, an aromatic ester-amide, an aromatic amide, or a combination thereof, Z is a substituted or unsubstituted aliphatic group including a double bond or a triple bond, a substituted or unsubstituted alicyclic group including a double bond or a triple bond, a substituted or unsubstituted aryl group including a double bond or a triple bond, (iso)cyanate, a derivative thereof, or a combination thereof, and n is an integer ranging from 1 to about 4.
US08552112B2
The present invention provides a weather resistant thermoplastic resin with low gloss and a method of preparing the same. The thermoplastic resin of the present invention comprises a (meth)acrylic acid alkyl ester-based polymer (A) and a (meth)acrylic acid alkyl ester-based oligomeric prepolymer (B), and an aromatic vinyl-cyanide vinyl based copolymer (C), wherein the (meth)acrylic acid alkyl ester-based polymer (A) and the (meth)acrylic acid alkyl ester-based oligomeric prepolymer (B) form a network-shaped disperse phase and the aromatic vinyl-cyanide vinyl based copolymer (C) forms a continuous phase.
US08552111B2
A composition comprises a polyvinylchloride homopolymer, a biodegradable plasticizer and either a swelling agent or a carbohydrate coupled to the polyvinylchloride homopolymer or a combination thereof. The composition may further comprise a blowing agent. A coated fabric comprises a textile substrate and a biodegradable coating at least partially coating the textile substrate, wherein the biodegradable coating degrades at least 60% after 28 days under the ASTM D584 standard. A method of making a biodegradable coating comprises providing a polymer and blending a biodegradable plasticizer with the polymer to form a blend. A method of making a coated textile comprises providing a textile and a composition comprising a polymer, a biodegradable plasticizer, and at least one other component; applying the composition to the textile; and curing the composition, thereby making a coated textile.
US08552110B2
Polymerization process for preparing mono-disperse organic/inorganic nanocomposite microspheres in the field of nano technology is disclosed. The process comprises preparing of two different miniemulsion systems of A with inorganic nanoparticles and B with polymeric monomers in advance; adding water-soluble initiator into miniemulsion A, stirring till complete dissolution finally, heating the mixed system to a given temperature for isothermal reaction. The grain size of the as-prepared superparamagnetic Fe3O4/polystyrene using to present invention is homogeneous and controllable, and the magnetic particles content is controllable.
US08552106B2
A fluorosilicone reaction product of a mercapto or vinyl functional organopolysiloxane and a fluorine-containing monomer, and methods of preparing the fluorosilicone are disclosed. The fluorosilicone products are suitable for application to substrates such as textiles, particularly fabrics, to impart oil repellent properties to the textile. The fluorosilicone reaction product is prepared from (A) a fluorine-containing monomer of the formula CH2═C(X)COOYRf, and (B) a mercapto or vinyl functional organopolysiloxane.
US08552099B2
A polymer additive for improving the reheat characteristics of a polymer or polymeric composition comprises an inorganic material which is such that a 2.5 mm thick polyethylene terephthalate plaque incorporating the inorganic material has, when tested, an absorption ratio of less than 0.9, wherein the absorption ratio is either the ratio of A1/A2 or the ratio A1/A3, wherein: A1 is the maximum absorption between 400 nm and 550 nm; A2 is the maximum absorption between 700 to 1100 nm; A3 is the maximum absorption between 700 to 1600 nm. Preferred inorganic materials are titanium nitride, indium tin oxide and lanthanum hexaboride.
US08552086B2
A hardenable dental composition that includes a polymerizable component and an organogelator.
US08552058B2
The invention discloses the application of l-n-butylphthalide as formula (I) in preparing a medicine for preventing and treating dementia, in special Alzheimer's disease and vascular dementia.
US08552057B2
Select phytoestrogen pharmaceutical compositions and methods of use for promoting neurological heath and prevention of age-related neurodegeneration, such as AD, have been developed. These select phytoestrogen formulations are composed of a number of plant-derived estrogenic molecules and/or their structural analogues and exhibit binding preference to ERβ over ERα and agonist activity in the brain. These ERβ-selective phytoestrogen formulations cross the blood-brain-barrier and promote estrogen-associated neurotrophism and neuroprotections mechanisms in the brain, without activating proliferative mechanisms in the reproductive tissues and are therefore devoid of other estrogen-associated problematic aspects. These are administered enterally, transdermally, transmucosally, intranasally or parenterally, in a dosage effective to prevent or alleviate neuronal damage, effect neuronal regeneration or sustain viability, increase expression of anti-apoptotic proteins, and/or decrease indicators of Alzheimer's Disease.
US08552034B2
A pharmaceutical composition comprising Compound 1, (3-(6-(1-(2,2-difluorobenzo[d][1,3]dioxol-5-yl)cyclopropanecarboxamido)-3-methylpyridin-2-yl)benzoic acid), and at least one excipient selected from: a filler, a diluent, a disintegrant, a surfactant, a binder, a glidant and a lubricant, the composition being suitable for oral administration to a patient in need thereof to treat a CFTR mediated disease such as Cystic Fibrosis. Methods for treating a patient in need thereof include administering an oral pharmaceutical formulation of Compound 1 to the patient.
US08552028B2
A compound is provided. The compound includes a formula of:
US08552027B2
Dyes and photoluminescent compounds based on polymethine dyes that contain at least one alkyl-phosphonate or substituted alkyl-phosphonate group, including the synthetic precursors, methods of synthesis, and applications thereof. Certain embodiments include heterocyclic ring systems and polymethine linkage are selected such that the resulting polymethine dye is a cyanine dye, a merocyanine dye, or a styryl dye.
US08552026B2
The present invention relates to an isatin derivative having the formula (I), a medicament for treatment of tuberculoses containing that isatin derivative as well as a method for preparing isatin derivative according to formula (I).
US08552021B2
Compounds of formula I: including any possible stereoisomers thereof, wherein: R1 is hydrogen, —C(═O)R6 or —C(═O)CHR7—NH2; R2 is hydrogen; or C1-C6alkyl or phenyl, either of which is optionally substituted with 1, 2 or 3 substituents each independently selected from halo, C1-C6alkyl, C2-C6-alkenyl and C1-C6alkoxy, hydroxy or amino, or R2 is naphtyl; or R2 is indolyl, R3 is hydrogen, C1-C6alkyl, benzyl; R4 is hydrogen, C1-C6alkyl, benzyl; or R3 and R4 together with the carbon atom to which they are attached form C3-C7cycloalkyl; R5 is C1-C10alkyl, C3-C7-cycloalkyl, benzyl, or phenyl, any of which being optionally substituted with 1, 2 or 3 substituents each independently selected from hydroxy, C1-C6alkoxy, amino, mono- and diC1-C6alkylamino; R6 is C1-C6 alkyl; R7 is C1-C6 alkyl; R8 is hydrogen or halogen; or a pharmaceutically acceptable salt or solvate thereof are useful in the prophylaxis or treatment of HCV infections.
US08552014B2
A method for treating cancer tumors, particularly ovarian cancer tumors, is described, where fused cyclic pyrimidine having a cancer treating ability is selectively delivered to an FR expressing cancerous tumor.
US08552013B2
Novel heterocyclic derivatives based on N6-substituted adenine, having anticancer, mitotic, immunosuppressive and antisenescent properties for plant, animal and human cells and methods of their preparation. Included are also pharmaceutical compositions, cosmetic preparations and growth regulators, which contain these derivatives as active compound and the use of these derivatives for the preparation of drugs, cosmetic preparations, in biotechnological processes, in cosmetics and in agriculture.
US08552007B2
Disclosed are compounds of Formula 1, wherein X is O or S; Y is O or S; and R1, R2, R3 and R4 are as defined in the disclosure. Also disclosed are compositions containing the compounds of Formula 1 and methods for controlling an invertebrate pest comprising contacting the invertebrate pest or its environment with a biologically effective amount of a compound or a composition of the invention.
US08552006B2
The present invention relates to compounds of formula IVA, formula IVB, or formula IVC, useful as modulators of ATP-Binding Cassette (“ABC”) transporters or fragments thereof, including Cystic Fibrosis Transmembrane Conductance Regulator, compositions thereof, and methods therewith. The present invention also relates to methods of treating diseases using such CFTR modulators.
US08551993B2
Novel compounds of the general formula (I), the use of these compounds as pharmaceutical compositions, pharmaceutical compositions comprising the compounds and methods of treatment employing these compounds and compositions. The present compounds are activators of PPARδ and should be useful for treating conditions mediated by the same.
US08551991B2
An object of the present invention is to synthesize a novel 1,2,3,4-tetrahydroquinoxaline derivative represented by formula (1) and to find a pharmacological action of the derivative. In the formula, the R1 represents a halogen, an alkyl, cycloalkyl, aryl or heterocyclic group, or the like; p represents 0 to 5; R2 represents a halogen, an alkyl, hydroxyl or alkoxy group, or the like; q represents 0 to 2; R3 represents hydrogen, an alkyl, alkenyl, alkylcarbonyl or arylcarbonyl group, or the like; R4 and R5 independently represent hydrogen, a halogen, an alkyl, alkenyl, alkynyl, cycloalkyl, aryl or heterocyclic group, or the like; R6 represents hydrogen, an alkyl, alkenyl, alkynyl, cycloalkyl, aryl or heterocyclic group, or the like; A represents an alkylene; R7 represents OR8, NR8R9, SR8, S(O)R8, S(O)2R8; and X represents O or S.
US08551987B2
The invention relates to the novel salts AB of the base A with a physiologically acceptable acid B which is selected from the group consisting of hydrochloric acid, hydrobromic acid, sulfuric acid, fumaric acid and salicylic acid and the polymorphic compounds, the corresponding solvates and hydrates thereof.
US08551984B2
The present invention provides novel pyrimidine amines of formula (I) which are potent inhibitors of spleen tyrosine kinase, and are useful in the treatment and prevention of diseases mediated by said enzyme, such as asthma, COPD and rheumatoid arthritis.
US08551974B1
Ophthalmic compositions are provided that include a lubricant, a deturgescent agent, a glycosaminoglycan, and water. Methods of using the ophthalmic compositions are also provided.
US08551973B2
A purified compound having activity against hepatitis C virus is disclosed.
US08551966B2
3-(2′,3′-dideoxy-ribo-β-L-furanosyl)[2,3-d]pyrimidin-2(3H)-one derivatives comprising 6-substitutents on the base moiety are shown to have anti-viral properties, particularly with respect to vaccinia and measles. The compounds have unnatural L ribose stereochemistry.
US08551955B2
The invention provides small molecule mimics of the Smac peptide that are dimers or dimer-like compounds having two binding domains connected by a linker. These compounds are useful to promote apoptosis. The invention includes pharmaceutical compositions comprising such compounds and methods to use them to treat conditions including cancer and autoimmune disorders.
US08551952B2
Provided herein are methods for treatment of ocular diseases. The methods comprise administering a compound of general Formula (I): wherein R1, R2, R3, R4 and Ak are as defined in the specification.
US08551947B2
Hibernating myocardium is characterized by viable myocardium with impaired function due to localized reduced perfusion. Hibernating myocytes retain cellular integrity, but cannot sustain high-energy requirements of contraction. High plasma levels of catecholamines, such as norepinepherine, are believed to be predictive of mortality from hibernating myocardium. Likewise, high levels of catecholamines lead to cardiomyopathy in patients with diabetes. GLP-1 reduces plasma norepinepherine levels, and it thus is useful in a method of treating hibernating myocardium or diabetic cardiomyopathy.
US08551946B2
Provided herein are peptide combinations comprising a GIP agonist peptide and a glucagon antagonist peptide. In some embodiments, the peptide combination is provided as a composition, e.g., a pharmaceutical composition, while in other embodiments, the peptide combination is provided as a kit. In yet other embodiments, the peptide combination is provided as a conjugate, e.g., a fusion peptide, a heterodimer. In specific aspects, the GIP agonist peptide is an analog of native human glucagon. In specific aspects, the glucagon antagonist peptide is an analog of native human glucagon. In some embodiments, the GIP agonist peptide is covalently attached to the glucagon antagonist peptide via a linker. Methods of treating a disease, e.g., a metabolic disorder, such as diabetes and obesity, comprising administering the peptide compositions described herein are further provided.
US08551939B2
The use is claimed of opioid peptides with a novel structure, which in addition to the pharmacophore contain structural elements that interact with neurotensisn receptors. Due to the synergistic interaction with the additional element, an augmented analgesic activity is obtained, capable of being used for an extended period due to decreased drug tolerance induction. These compounds may be of particular use in the treatment of chronic pain as effective analgesics during inflammation caused by rheumatoid, gout, neurodegeneration, post-operative or post-accidental lesions, or oncogenic lesions.
US08551932B2
A liquid hard surface cleaning composition includes melamine foam fibers. In one embodiment the composition has a pH of from about 7 to about 12. In another embodiment, the composition comprises less than about 200 ppm of formaldehyde in solution, per about 1% by weight of melamine foam fibers present in the composition, after 7 days of storage at 50 C.
US08551929B2
The present invention provides unit dose detergent products, such as those in the form of compositions comprising: a water-soluble single-chamber container, such as a pouch; and a cleaning system comprising at least one detersive surfactant, and optionally one or more additional components. The invention also provides methods of production of such compositions, and methods use of such compositions in processes for cleaning dishware and/or fabrics, including garments, by introducing one or more of the unit dose products of the invention into an automatic washing machine suitable for washing dishware or laundry, whereby the cleaning system is released such that it comes into contact with a soiled article (e.g., dishware or fabrics) under conditions favoring the removal of one or more soils from the article.
US08551928B2
A multi-agent type cleaning kit for applying to semiconductor substrates, which contains a foaming agent having an alkylene carbonate and a carbonic acid salt, a foaming aid having an acidic compound, and an oxidizing agent; at least the foaming agent is mixed with the foaming aid upon using for the cleaning of a semiconductor substrate, in combination with the oxidizing agent.
US08551926B2
Emulsified acids have been used to increase production rates of oil and gas in carbonate reservoirs through acid fracturing and matrix acidizing operations. An emulsifier is used to emulsify the aqueous acid with an oil, usually diesel. Very small particles, such as colloidal clay particles and/or nanoparticles increase the stability of the emulsified acids over an elevated temperature range.
US08551922B1
In a process of fabricating a tissue array, a tissue block is sliced to obtain sheet-form pieces of tissue, and each of the sheet-form pieces is closely rolled around a guide member to form a spiral shape tissue around the guide member. Then, the spiral shape tissues are inserted in an axial direction into holes arrayed in a base block.
US08551921B2
An indicator device, and a biological test method, for determining the toxic fingerprint and degree of toxicity, comprising at least 3, preferably at least 11, different microorganisms freeze-dried on an inert support material, wherein the microorganisms are being selected to form a high diversity of microorganisms, on the support material, with regards to the taxonomical tree and high diversity regarding responses to toxic chemicals. Further, a kit and a process for producing the indicator device is also disclosed.
US08551918B2
A herbicidal composition comprising, in addition to customary inert formulation excipients, as a mixture of at least one soil-applied herbicide and a lipophilic additive consisting of a paraffin oil derived from the refined fraction of petroleum oil with a distillation range at 10 mm Hg of about 190 °C. to about 280 °C. and with a carbon number distribution from about C13 to about C55.
US08551915B2
The present invention provides a product for agricultural use in the form of granules or pellets, characterized by comprising at least 30% (w/w) of vinasses and/or sludge measured as a dry extract of vinasses and/or sludge, and an organic or inorganic solid support. In addition, the present invention provides a procedure for producing said product, its use in agriculture, stockbreeding or as biodiesel.
US08551914B2
Molecules having the following structure are disclosed. Processes of using such molecules are disclosed.
US08551910B2
The invention relates to a porous structure comprising a ceramic material comprising mainly or consisting of an oxide material of the pseudobrookite type comprising titanium, aluminum, magnesium and zirconium in proportions such that the phase of the pseudobrookite type substantially satisfies the formula: (Al2TiO5)x(MgTi2O5)y(MgTiZrO5)z. This material satisfies the following composition, in mol % on the basis of just the oxides Al2O3, TiO2, MgO and ZrO2: 90<2a+3m<110; 100+a<3t<210−a; and a+t+m+zr=100, in which: a is the molar content of Al2O3; t is the molar content of TiO2; m is the molar content of MgO; and zr is the molar content of ZrO2.
US08551906B2
The invention relates to a titanate photocatalyst of formula (I): HmAx-mTiyOzDn (I) wherein: A is a cation selected from the group consisting of lithium, sodium, potassium, rubidium, caesium and francium; D is a dopant selected from the group consisting of boron, carbon, nitrogen, fluorine, sulphur, phosphorus and iodine; x is a value between 0 and 8; y is a value greater than 0 and less than or equal to 8; n is a value greater than 0 and less than or equal to 8; z is a value greater than 0 and less than or equal to 8; and m is a value between 0 and 8. The invention also relates to method of production and uses of the titanate photocatalyst.
US08551897B2
Provided are inorganic fibers containing calcium and alumina as the major fiber components. According to certain embodiments, the inorganic fibers containing calcia and alumina are provided with a coating of a phosphorous containing compound on at least a portion of the fiber surfaces. Also provided are methods of preparing the coated and non-coated inorganic fibers and of thermally insulating articles using thermal insulation comprising the inorganic fibers.
US08551888B2
A method of forming patterns for a semiconductor device. The method includes: forming a first hard mask layer on a layer which is to be etched; forming a second hard mask layer on the first hard mask layer, wherein the second hard mask layer includes a first portion and a second portion formed underneath the first portion, wherein the first portion and second portion are composed of the same material; etching the first portion to form first patterns; forming spacers covering sidewalls of the first patterns; etching the second portion using the spacers as etch masks to form second patterns; etching the first hard mask layer and the spacers using the second patterns disposed underneath the spacers as etch masks to form third patterns; and etching the layer to be etched, using the third patterns.
US08551886B2
A method for semiconductor processing is provided wherein a workpiece having an underlying body and a plurality of features extending therefrom, is provided. A first set of the plurality of features extend from the underlying body to a first plane, and a second set of the plurality features extend from the underlying body to a second plane. A protection layer overlies each of the plurality of features and an isolation layer overlies the underlying body and protection layer, wherein the isolation has a non-uniform first oxide density associated therewith. The isolation layer anisotropically etched based on a predetermined pattern, and then isotropically etched, wherein a second oxide density of the isolation layer is substantially uniform across the workpiece. The predetermined pattern is based, at least in part, on a desired oxide density, a location and extension of the plurality of features to the first and second planes.
US08551883B2
The invention relates to a method for masking a semiconductor substrate including the following steps: providing a planar semiconductor substrate having a first side and a second side lying opposite thereto, applying a mask to at least one of the sides, an extrusion printing method being used for applying the mask.
US08551882B2
In one embodiment, a semiconductor is provided comprising a substrate and a plurality of wiring layers and dielectric layers formed on the substrate, the wiring layers implementing a circuit. The dielectric layers separate adjacent ones of the plurality of wiring layers. A first passivation layer is formed on the plurality of wiring layers. A first contact pad is formed in the layer and connected to the contact pad. A through silicon via (TSV) is formed through the substrate, the plurality of wiring and dielectric layers, and the passivation layer. The TSV is electrically connected to the wire formed on the passivation layer. The TSV is electrically isolated from the wiring layers except for the connection provided by the metal wire formed on the passivation layer.
US08551879B2
A semiconductor device includes a first conductor formed over a semiconductor device; an insulation film formed over the semiconductor substrate and the first conductor and having an opening arriving at the first conductor; a first film formed in the opening and formed of a compound containing Zr; a second film formed over the first film in the opening and formed of an oxide containing Mn; and a second conductor buried in the opening and containing Cu.
US08551876B2
A manufacturing method for a semiconductor device having a metal gate includes providing a substrate having at least a first semiconductor device formed thereon, forming a first gate trench in the first semiconductor device, forming a first work function metal layer in the first gate trench, and performing a decoupled plasma oxidation to the first work function metal layer.
US08551871B2
A method of fabricating a semiconductor device according to one embodiment includes: exposing a surface of a semiconductor substrate to a halogen-containing gas that contains at least one of Si and Ge, the semiconductor substrate being provided with a member comprising an oxide and consisting mainly of Si; and exposing the surface of the semiconductor substrate to an atmosphere containing at least one of a Si-containing gas not containing halogen and a Ge-containing gas not containing halogen after starting exposure of the surface of the semiconductor substrate to the halogen-containing gas, thereby epitaxially growing a crystal film containing at least one of Si and Ge on the surface.
US08551858B2
A method for fabricating a memory device with U-shaped trap layers over rounded active region corners is disclosed. In the present invention, an STI process is performed before the charge-trapping layer is formed. Immediately after the STI process, the sharp corners of the active regions are exposed, making them available for rounding. Rounding the corners improves the performance characteristics of the memory device. Subsequent to the rounding process, a bottom oxide layer, nitride layer, and sacrificial top oxide layer are formed. An organic bottom antireflective coating applied to the charge trapping layer is planarized. Now the organic bottom antireflective coating, sacrificial top oxide layer, and nitride layer are etched, without etching the sacrificial top oxide layer and nitride layer over the active regions. After the etching the charge trapping layer has a cross-sectional U-shape appearance. U-shaped trap layer edges allow for increased packing density and integration while maintaining isolation between trap layers.
US08551857B2
The technique for manufacturing a high-capacitance and high-accuracy MIM electrostatic capacitor by a small number of steps is provided. After a lower electrode of the electrostatic capacitor and second wiring are formed at the same time on a first interlayer insulating film, an opening part is formed in a second interlayer insulating film deposited on the first interlayer insulating film. Next, a capacitance insulating film, a second metal film and a protective metal film are sequentially deposited on the second interlayer insulating film including the interior of the opening part, and the protective metal film, the second metal film and the capacitance insulating film on the second interlayer insulating film are polished and removed by a CMP method, thereby causing the capacitance insulating film, an upper electrode made of the second metal film and the protective metal film to remain in the opening part.
US08551856B2
Methods are provided for forming a capacitor. In one embodiment, a method comprises providing an insulator material layer over a substrate, etching at least one via in the insulator material layer and depositing a contact material fill in the at least one via to form a first set of contacts. The method further comprises etching the insulator material layer adjacent at least one contact of the first set of contacts to form at least one void, depositing a dielectric material layer over the at least one void and over the first set of contacts and depositing a contact material fill in the at least void to form a second set of contacts.
US08551851B2
This disclosure provides (a) methods of making an oxide layer (e.g., a dielectric layer) based on titanium oxide, to suppress the formation of anatase-phase titanium oxide and (b) related devices and structures. A metal-insulator-metal (“MIM”) stack is formed using an ozone pretreatment process of a bottom electrode (or other substrate) followed by an ALD process to form a TiO2 dielectric, rooted in the use of an amide-containing precursor. Following the ALD process, an oxidizing anneal process is applied in a manner is hot enough to heal defects in the TiO2 dielectric and reduce interface states between TiO2 and electrode; the anneal temperature is selected so as to not be so hot as to disrupt BEL surface roughness. Further process variants may include doping the titanium oxide, pedestal heating during the ALD process to 275-300 degrees Celsius, use of platinum or ruthenium for the BEL, and plural reagent pulses of ozone for each ALD process cycle. The process provides high deposition rates, and the resulting MIM structure has substantially no x-ray diffraction peaks associated with anatase-phase titanium oxide.
US08551837B2
Methods of fabricating semiconductor devices with high-k/metal gate features are disclosed. In some instances, methods of fabricating semiconductor devices with high-k/metal gate features are disclosed that prevent or reduce high-k/metal gate contamination of non-high-k/metal gate wafers and production tools. In some embodiments, the method comprises forming an interfacial layer over a semiconductor substrate on a front side of the substrate; forming a high-k dielectric layer and a capping layer over the interfacial layer; forming a metal layer over the high-k and capping layers; forming a polysilicon layer over the metal layer; and forming a dielectric layer over the semiconductor substrate on a back side of the substrate.
US08551834B2
The present invention relates to providing layers of different thickness on vertical and horizontal surfaces (15, 20) of a vertical semiconductor device (1). In particular the invention relates to gate electrodes and the formation of precision layers (28) in semiconductor structures comprising a substrate (10) and an elongated structure (5) essentially standing up from the substrate. According to the method of the invention the vertical geometry of the device (1) is utilized in combination with either anisotropic desposition or anisotropic removal of deposited material to form vertical or horizontal layers of very high precision.
US08551829B2
A method for manufacturing a multi-gate transistor device includes providing a semiconductor substrate having a first patterned semiconductor layer formed thereon, sequentially forming a gate dielectric layer and a gate layer covering a portion of the first patterned semiconductor layer on the semiconductor substrate, removing a portion of the first patterned semiconductor layer to form a second patterned semiconductor layer, and performing a selective epitaxial growth process to form an epitaxial layer on a surface of the second patterned semiconductor layer.
US08551814B2
A wafer structure (88) includes a device wafer (20) and a cap wafer (60). Semiconductor dies (22) on the device wafer (20) each include a microelectronic device (26) and terminal elements (28, 30). Barriers (36, 52) are positioned in inactive regions (32, 50) of the device wafer (20). The cap wafer (60) is coupled to the device wafer (20) and covers the semiconductor dies (22). Portions (72) of the cap wafer (60) are removed to expose the terminal elements (28, 30). The barriers (36, 52) may be taller than the elements (28, 30) and function to prevent the portions (72) from contacting the terminal elements (28, 30) when the portions (72) are removed. The wafer structure (88) is singulated to form multiple semiconductor devices (89), each device (89) including the microelectronic device (26) covered by a section of the cap wafer (60) and terminal elements (28, 30) exposed from the cap wafer (60).
US08551809B2
A nonvolatile memory device and methods of manufacturing the same has one electrode with a higher work function and a second electrode with a lower work function. The nonvolatile memory device further comprises one or more resistive random access memory (RRAM) cells. The RRAM cells comprise a semiconductor layer with a bandgap of at least four electron volts and a barrier layer between the semiconductor layer and one of the electrodes.
US08551806B2
Methods for passivating a carbonic nanolayer (that is, material layers comprised of low dimensional carbon structures with delocalized electrons such as carbon nanotubes and nano-scopic graphene flecks) to prevent or otherwise limit the encroachment of another material layer are disclosed. In some embodiments, a sacrificial material is implanted within a porous carbonic nanolayer to fill in the voids within the porous carbonic nanolayer while one or more other material layers are applied over or alongside the carbonic nanolayer. Once the other material layers are in place, the sacrificial material is removed. In other embodiments, a non-sacrificial filler material (selected and deposited in such a way as to not impair the switching function of the carbonic nanolayer) is used to form a barrier layer within a carbonic nanolayer. In other embodiments, carbon structures are combined with and nanoscopic particles to limit the porosity of a carbonic nanolayer.
US08551803B2
Provided is a process of producing a solar battery module 1 including plural solar battery cells 4 sealed by a resin 5 between a transparent panel 2 of the light reception surface side and a back face panel 3, which is characterized by arranging plural solar battery cells 4 at a prescribed interval and mutually connecting them to each other by a conductor 8; arranging a first sealing resin sheet 12 substantially covering the entire surface of the transparent panel 2 of the light reception surface side between the transparent panel 2 of the light reception surface side and the solar battery cells 4; arranging a second sealing resin sheet 10 substantially covering the entire surface of the back face panel 3 between the back face panel 3 and the solar battery cells 4; arranging sealing resin sheet pieces 18, 19 which are thicker than the solar battery cells 4 at a space 9 between the solar battery cells 4 so as to be sandwiched by the first sealing resin sheet 12 and the second sealing resin sheet 10; discharging air between the transparent panel 2 of the light reception surface side and the back face panel 3; and heating the resin 5 for melting and then cooling down it for sealing. According to this, when the plural solar battery cells 4 are arranged and sealed by the resin 5, breakage of the solar battery cells 4 can be prevented from occurring.
US08551797B2
A method for fabricating a semiconductor laser includes: sequentially forming a cladding layer of a first conductivity type, an active layer, a cladding layer of a second conductivity type, and a contact layer of the second conductivity type on a semiconductor substrate; forming a promotion film which contacts the contact layer only in a window region proximate an end plane of the semiconductor laser and absorbs group-III atoms from the contact layer to promote generation of group-III vacancies; implanting ions into the contact layer in the window region to damage the contact layer in the window region; and after forming the promotion film and implanting the ions, heat treating so that the group-III vacancies are diffused and the active layer is disordered in the window region and forms a window structure.
US08551792B2
A method of dicing a semiconductor wafer comprises scribing at least one dielectric layer along dice lanes to remove material from a surface of the wafer using a laser with a pulse-width between 1 picosecond and 1000 picoseconds and with a repetition frequency corresponding to times between pulses shorter than a thermal relaxation time of the material to be scribed. The wafer is then diced through a metal layer and at least partially through a substrate of the semiconductor wafer.
US08551791B2
Apparatus and method for manufacturing a semiconductor device through a layer material dimension analysis increase productivity. The method includes performing a semiconductor manufacturing process of at least one reference substrate and at least one target substrate in a semiconductor process device, detecting a reference spectrum and a reference profile for the reference substrate, determining a relation function between the detected reference spectrum and reference profile, detecting a real-time spectrum of the target substrate, and determining in real time a real-time profile of the target substrate processed in the semiconductor process device by using the detected real-time spectrum as a variable in the determined relation function.
US08551779B2
The invention relates to a method of identifying, obtaining and/or quantifying a culture of pancreatic cells selected from the group consisting of ductal/endocrine progenitor cells, endocrine progenitor cells, early endocrine cells, and fully differentiated endocrine cells. Also contemplated is a method of expanding the numbers of such cells as well as sorting such cells. The invention further relates to a selective cell surface marker, DDR1, that permits the selection of a unique subset of cells with pancreatic endocrine progenitor phenotype. Furthermore, the invention relates to isolated cells selected from such cells and compositions thereof.
US08551778B2
The invention relates to a method for producing a preform by means of an electrospinning process. The present invention also relates to the use of the present preform as a substrate for growing human or animal tissue thereon. The present invention furthermore relates to a method for growing human or animal tissue on a substrate, wherein the present preform is used as the substrate.
US08551773B2
The present invention provides HIV-derived lentivectors which are safe, highly efficient, and very potent for expressing transgenes for human gene therapy, especially, in human hematopoietic progenitor cells as well as in all other blood cell derivatives. The lentiviral vectors comprise a self-inactivating configuration for biosafety and promoters such as the EF1α promoter as one example. Additional promoters are also described. The vectors can also comprise additional transcription enhancing elements such as the wood chuck hepatitis virus post-transcriptional regulatory element. These vectors therefore provide useful tools for genetic treatments such as inherited and acquired lympho-hematological disorders, gene-therapies for cancers especially the hematological cancers, as well as for the study of hematopoiesis via lentivector-mediated modification of human HSCs.
US08551763B2
In a method and system for forming concentrated volumes of microbeads, a polymer solution and/or suspension includes a polymer dissolved and/or dispersed in a medium. Streams of a focusing fluid and of the polymer solution and/or suspension flow towards a fluid bath, and into intersection with one another, so &s to focus the polymer solution and/or suspension. The polymer solution and/or suspension stream forms microbeads in the fluid bath. Some of the focusing fluid is drawn from the fluid bath, so as to concentrate the microbeads in die fluid bath. The system includes a flow focusing apparatus and a liquid-containing cell. The focusing apparatus includes polymer and focusing nozzles. The cell contains the fluid bath and has an outlet port, through which the focusing fluid is drawn from the fluid bath.
US08551757B2
A novel bacterial strain of Bacillus thuringiensis, VBTS 2528, is described. This strain comprises genes encoding Cry1Ac, Cry 1Ca, and Cry2Aa endotoxin proteins. The invention further relates to an insecticidal composition comprising a mixture of VBTS 2528 and to methods for controlling insect pests utilizing VBTS 2528.
US08551749B2
Devices, methods, and systems are described for controlling pathogenic condition or disease in a subject. Devices are described that include one or more bone cages. The device including one or more bone cages can be configured to include one or more immunogens and one or more adjuvants. The device including one or more bone cages can be configured to, and/or structured to at least partially or completely surround one or more cells or tissues that produce one or more immunogens and/or one or more adjuvants. The device is useful in a method for treating a pathogenic condition or disease in the subject.
US08551742B2
Described herein are microorganisms that produce methionine and related products from endogenous genes in a transsulfuration pathway, as well as from exogenous genes providing a direct sulfhydrylation pathway. Novel genes that are useful for methionine and SAMe production are disclosed.
US08551738B2
There is a need for nucleic acid analysis which is both specific and rapid, and in which no nucleic acid sequencing is required. The present invention addresses this need, among others by providing a method of nucleic acid amplification of overlapping sub-segments of a nucleic acid followed by molecular mass measurement of resulting amplification products by mass spectrometry, and determination of the base compositions of the amplification products.
US08551735B2
Human neutrophil peptide (HNP) 1-3, used as diagnostic and therapeutic molecular probes, are found in clinical tissues of gastric cancer patients. In the analytical process according to the present disclosure, pairs of gastric cancer tissues are used to seek the putative biomarkers by proteomic strategy based on matrix assisted laser desorption ionization-imaging mass spectrometry (MALDI-IMS). Then, three differential biomarkers, including HNP-1, -2 and -3, are identified (P<0.001) and overexpressed in gastric cancer. At last, western blotting and immunohistochemistry are used to validate the protein expression in gastric cancer tissues. In conclusion, the use of the up-regulated proteins, HNP1-3, helps diagnosis and therapy in clinical for gastric cancer after validating the sensitivity and specificity.
US08551730B2
Methods of microscopic imaging of biological tissue using adaptive optics technology to improve the image focus and sharpness. Wavefront measurements are taken by using a novel method of seeding biological tissue by using a fluorescent microsphere as a “guide star” as a natural point-source reference. The current methods are capable of improving the Strehl ratio of modern biological microscopes as much as 15 times.
US08551729B2
The invention relates to the use of mutants of L. casei having at least a mutation impairing the regulation of a carbon catabolite repression (CCR) mechanism involving the PTS protein HPr, for the preparation of a food product.The use of said mutants allows for instance to impart to said food products an improved texture and flavor, and/or a higher content in aroma compounds.
US08551724B2
A method is described for improving the nutritional value of a foodstuff comprising a source of myo-inositol hexakisphosphate by feeding the foodstuff in combination with a phytase expressed in yeast. The method comprises the step of feeding the animal the foodstuff in combination with a phytase expressed in yeast wherein the phytase can be selected from the group consisting of AppA1, AppA2 and a site-directed mutant of AppA. The invention also enables reduction of the feed to weight gain ratio and an increase bone mass and mineral content of an animal. A foodstuff and a feed additive comprising AppA2 or a site-directed mutant of AppA are also described.
US08551723B2
The present invention relates to a tyrosine kinase-inducible domain (pKID) and uses thereof. An isolated polypeptide comprising the pKID, and an isolated polynucleotide comprising a nucleic acid sequence encoding the pKID are provided. Also provided are methods for determining tyrosine kinase and/or phosphatase activity in a sample and for identifying an agent that inhibits a tyrosine kinase or phosphatase using a polypeptide comprising the pKID.
US08551722B2
A method of determining the course of enzyme activity that is variable in time, wherein the activity is probed by conversion of a substrate of the enzyme, includes, in a selected test set up and for a determined substrate of the enzyme, determining the velocity of signal production (dFdiag/dt) resulting from a time curve of the signal (Fdiao=f(A)) obtained from splitting the substrate when it is contacted with a determined initially fixed concentration of the enzyme (E) and providing a “diagnostic plot” with the values of (dFdiag/dt) against the signal (Fdiag) and determining whether the diagnostic plot is either a straight line or a parabola and in the same test conditions, for a given test sample, determining the signal production (Fexp) resulting from splitting the substrate by the enzyme generating in and/or disappearing from the sample and providing the time curve of signal Fexp=f(t); and transforming the obtained experimental value of the signal (Fexp) into an ideal value (Ftransf).
US08551720B2
Provided herein are methods and materials for diagnosing a bowel disease in a subject by detecting the presence or absence of a bowel disease marker. A bowel disease marker has been identified as AKR1B10 and may be useful in identifying subjects at risk for bowel disease, predicting bowel disease progression, and assessing a subject's response to therapy.
US08551718B2
The present invention provides novel functional assay for 5-HT2A, histamine H1 or adrenergic alpha 1b receptors, by measuring intracellular cyclic adenosine monophosphate (cAMP) levels utilizing reporter gene driven cell based assay. The novel assay provides both binding affinity as well as mode of action of compounds in a single set. The novel assay of the invention is useful in identification of compounds acting through 5-HT2A, histamine H1 or adrenergic alpha 1b receptors. Furthermore, the assay offers utility in categorizing compounds in to agonist, partial agonist, inverse agonist and antagonist classes. The novel assay can be scaled up to any high throughput format.
US08551715B2
The invention relates to novel polypeptides and cells comprising the polypeptides. The polypeptides and cells are used in methods to identify and/or isolate cells producing a protein with specific biological functions. In particular, the methods may be used for identifying, selecting, and isolating cells producing antigen-specific monoclonal antibodies.
US08551713B1
The present invention relates to a series of markers and a method of determining cause of death post-mortem by quantifying thymus integrity. An examination of thymuses from human infants suffering mortal head trauma revealed a disruption of the cortical-medullary organization of the thymus, particularly involving dissolution of the cortical-medullary border. A similar result was obtained for related mouse and rat models. The human thymuses from head trauma cases also displayed a higher percentage of Ki67-positive thymocytes.
US08551708B2
The present invention relates to the detection of RNA in a sample of cells. More particularly, the present invention relates to the localized detection of RNA in situ. The method relies on the conversion of RNA to complementary DNA prior to the targeting of the cDNA with a padlock probe(s). The hybridization of the padlock probe(s) relies on the nucleotide sequence of the cDNA which is derived from the corresponding nucleotide sequence of the target RNA. Rolling circle amplification of the subsequently circularized padlock probe produces a rolling circle product which may be detected. Advantageously, this allows the RNA to be detected in situ.
US08551706B2
West Nile virus capture oligonucleotides, primers and probes derived from conserved regions of the West Nile virus genome are disclosed. Also disclosed are nucleic acid-based assays using the capture oligonucleotides, primers and probes.
US08551705B2
Methods for propagating haploid genomes of male or female origina and genetic screening and modification thereof are provided. These haploid genomes may be used to produce haploid embryos, and embryonic stem-like cells and differentiated cells. Also, these haploid genomes and cells containing, may be used as nuclear transfer donors to produce diploid nuclear transfer units. These diploid NT units e.g., human NT units, may be used to obtain pluripotent cells and differentiated cells and tissues.
US08551704B2
The invention provides methods and compositions for the controlled termination of polymerase mediated primer extension reactions. The methods and compositions of the invention are broadly useful, and in a preferred aspect can be used in identifying sequence elements of template nucleic acids. Control of termination not only provides temporal control over termination, but, when used in conjunction with optically confined reaction regions, also spatially controls such termination.
US08551686B2
The invention relates to an antireflective coating composition for a photoresist layer comprising a polymer, a crosslinking agent and an acid generator, where the polymer comprises at least one unit of structure 1, where, X is a linking moiety selected from a nonaromatic (A) moiety, aromatic (P) moiety and mixture thereof, R′ is a group of structure (2), R″ is independently selected from hydrogen, a moiety of structure (2), Z and W—OH, where Z is a (C1-C20) hydrocarbyl moiety and W is a (C1-C20) hydrocarbylene linking moiety, and, Y′ is independently a (C1-C20) hydrocarbylene linking moiety, where structure (2) is where R1 and R2 are independently selected from H and C1-C4alkyl and L is an organic hydrocarbyl group. The invention further relates to a process for imaging the antireflective coating composition.
US08551682B2
Resist stripping agents useful for fabricating circuits and/or forming electrodes on semiconductor devices for semiconductor integrated circuits and/or liquid crystals with reduced metal and metal alloy etch rates (particularly copper etch rates and TiW etch rates), are provided with methods for their use. The preferred stripping agents contain low concentrations of resorcinol or a resorcinol derivative, with or without an added copper salt, and with or without an added amine to improve solubility of the copper salt. Further provided are integrated circuit devices and electronic interconnect structures prepared according to these methods.
US08551681B2
An emulsion aggregation toner formulation for electrophotography and a method for preparation thereof. The emulsion aggregation toner formulation includes a polyester resin emulsion formed using an extruded polyester binder resin having a broad molecular weight distribution. The extruded polyester binder resin is formed using a plurality of polyester binder resins. Further, the emulsion aggregation toner formulation comprises at least one colorant dispersion and a wax dispersion.
US08551679B2
A toner including a plurality of fine particles includes a core including first latex particles, a wax and a pigment, or a first latex particle-wax complex and a pigment, and a first shell layer including second latex particles and covering at least a portion of the surface of the core, a method of preparing the toner, a method of forming images using the toner, and an image forming device including a toner transferring unit. The toner can have improved fixing and charging properties, preserving properties at a high temperature and high humidity, glossness and anti-offset properties by reducing a domain size of a wax dispersed in the toner and improving dispersibility of the wax.
US08551671B2
A unit cell of a fuel cell is formed by stacking a membrane electrode assembly between a first metal separator and a second metal separator in a stacking direction. A frame is provided in an outer end of the membrane electrode assembly. A seal member is formed on the frame. The seal member includes a first seal as a fuel gas seal, a second seal as a coolant seal, and a third seal as an oxygen-containing gas seal. The first seal, the second seal, and the third seal are offset from each other in the stacking direction.
US08551670B2
An electrochemical device and methods of using the same. In one embodiment, the electrochemical device may be used as a fuel cell and/or as an electrolyzer and includes a membrane electrode assembly (MEA), an anodic gas diffusion medium in contact with the anode of the MEA, a cathodic gas diffusion medium in contact with the cathode, a first bipolar plate in contact with the anodic gas diffusion medium, and a second bipolar plate in contact with the cathodic gas diffusion medium. Each of the bipolar plates includes an electrically-conductive, chemically-inert, non-porous, liquid-permeable, substantially gas-impermeable membrane in contact with its respective gas diffusion medium, as well as a fluid chamber and a non-porous an electrically-conductive plate.
US08551658B2
To provide a process for a lithium-containing composite oxide for a positive electrode for a lithium secondary battery, which has a large volume capacity density and high safety, and is excellent in the charge and discharge cyclic durability and low temperature characteristics.A process for producing a lithium-containing composite oxide represented by the formula LipNxMyOzFa (wherein N is at least one element selected from the group consisting of Co, Mn and Ni, M is at least one element selected from the group consisting of Al, alkaline earth metal elements and transition metal elements other than N, 0.9≦p≦1.2, 0.95≦x≦2.00, 0
US08551650B2
Graphene-based storage materials for high-power battery applications are provided. The storage materials are composed of vertical stacks of graphene sheets and have reduced resistance for Li ion transport. This reduced resistance is achieved by incorporating a random distribution of structural defects into the stacked graphene sheets, whereby the structural defects facilitate the diffusion of Li ions into the interior of the storage materials.
US08551647B2
An electrode is provided with a metal terminal extending from a battery module main body, a bolt which has an expanded section configuring a retaining section at a rear end portion and penetrates the metal terminal upward, and an insulating body which insulates the metal terminal and the battery module case one from the other. The insulating body is provided with a drop preventing section which abuts at least a lower surface of the expanded section of the bolt and prevents the bolt from dropping from the metal terminal.
US08551645B2
A can for a cylindrical lithium rechargeable battery, and a cylindrical lithium rechargeable battery using the same is provided. The battery includes: an electrode assembly having cathode and anode plates facing to each other, a separator interposed between the cathode and anode plates, and cathode and anode taps formed on the cathode and anode plates, respectively; a can accommodating the electrode assembly; and a cap assembly to seal an opening of an upper end portion of the can. The can has surface plate and a lower plate, and a protrusion is formed on the lower plate so as to increase the contact resistance between the anode tap and the lower plate, when the anode tap is welded to the lower plate.
US08551643B2
A battery pack includes a battery housing, a battery cell having a tubular negative electrode having an opening part at one end and a positive electrode fixed to the negative electrode in such a way as to close the opening part, the battery cell being housed in the battery housing, and a protrusion disposed between the battery cell and the inner wall of the battery housing in an area other than an area where the positive electrode and the negative electrode of the battery cell are fixed.
US08551641B2
A pouch type secondary battery including a safety member. The pouch type secondary battery includes an electrode assembly including first and second electrode plates having opposite electrical polarities and a first separator between the first and second electrode plates; and a safety member including a first conductive plate located on an outside of the electrode assembly and electrically connected to the first electrode plate, a second conductive plate located on an outside of the first conductive plate and electrically connected to the second electrode plate, and an insulating plate between the first and second conductive plates for insulating the first and second conductive plates from each other, and the first conductive plate has a puncture strength that is greater than a puncture strength of the second conductive plate.
US08551634B2
A computer enclosure includes a frame portion and a battery holding structure. The frame portion defines a battery receiving groove for receiving a battery, a first sliding groove and a second sliding groove communicating with the battery receiving groove. The battery holding structure includes a first locking member movably received in the first sliding groove, a second locking member movably received in the second sliding groove, and a spring. The first locking member includes a first latching block. The second locking member includes a second latching block. The spring is compressed between the second locking member and an inner surface of the second sliding groove and configured to provide a force to push the second latching block into the battery receiving groove. The first and second latching members can be pushed into the battery receiving groove to cooperatively latch the battery in the battery receiving groove.
US08551627B2
This invention provides a magnetic disk which can satisfactorily suppress the elution of internal components from an end face of a magnetic disk, and corrosion damage. The magnetic disk comprises a disk substrate, and a thin film including a magnetic layer, a carbon-based protective layer, and a lubricating layer provided in that order on the disk substrate. The main surface and the end face of the magnetic disk are covered with the carbonaceous protective layer. The carbon-based protective layer contains nitrogen at a part adjacent to the lubricating layer. The content of nitrogen atoms relative to the content of carbon atoms in the protective layer formed on the end face is equal to or more than the content of nitrogen atoms relative to the content of carbon atoms in the protective layer formed on the main surface.
US08551626B2
A magnetoresistive device having a high giant magnetoresistance (GMR) value and a moderate low resistance area product (RA) includes a first magnetic layer, a second magnetic layer, and a current confined path (CCP) spacer layer positioned between the first magnetic layer and the second magnetic layer. The spacer layer includes copper current confined paths extending between the first magnetic layer and the second magnetic layer in a matrix of magnesium oxide. The spacer layer is formed by a mixture copper and magnesium oxide, which is heattreated to form the copper current confined paths within the magnesium oxide matrix.
US08551625B2
A derivative with a heteroaromatic ring represented by General Formula (G1) is provided. R11 to R20 in the formula independently represent a hydrogen atom, an alkyl group having 1 to 4 carbon atoms, or an aryl group having 6 to 10 carbon atoms in a ring. J represents a substituted or unsubstituted arylene group having 6 to 12 carbon atoms in a ring. Note that α and β may be bonded to each other to form a carbazole skeleton. Het is a substituent represented by General Formula (S1-1) or (S1-2). In General Formulae (S1-1) and (S1-2), Ar1 to Ar4 are independently a substituted or unsubstituted aryl group having 6 to 10 carbon atoms in a ring. R1 is a hydrogen atom, an alkyl group having 1 to 4 carbon atoms, or an aryl group having 6 to 10 carbon atoms in a ring.
US08551620B2
A multi-layer aircraft adhesive composition is provided having a first layer prepared from a first composition having a Part A and a Part B. Part A contains a plasticizer, a crosslinking agent, and an adhesion promoter. Part B contains a moisture resister and an abrasion resister. The composition has a second layer formed over at least a portion of the first layer. The second layer is prepared from a second composition having a Part C and a Part D. Part C contains at least one polythiol functional polymer, at least one epoxy resin, at least one sulfur containing material that is different from the at least one polythiol functional polymer, at least one plasticizer, and at least one filler. Part D contains at least one plasticizer, at least one of manganese dioxide or lead oxide, and at least one alkaline agent.
US08551615B2
Disclosed is a pressure-sensitive adhesive composition which contains an acrylic polymer and a crosslinking agent. The acrylic polymer has a weight-average molecular weight of 40×104 to 160×104 and contains at least an alkoxyalkyl acrylate (Component A) and an acrylic monomer having a crosslinkable functional group (Component B). The monomer components constituting the acrylic polymer contain 45 to 99.5 parts by weight of Component A and 0.5 to 4.5 parts by weight of Component B to 100 parts by weight of total monomer components constituting the acrylic polymer, and the monomer components constituting the acrylic polymer contain substantially no carboxyl-containing monomers. This relates to improvements to provide pressure-sensitive adhesive compositions that show excellent coatability, transparency, adhesion (typically low-temperature adhesion), and resistance to blistering/separation and concurrently have anticorrosive properties.
US08551610B2
The invention relates to a biaxially oriented, single-layer microporous film which has a shut-off function and is made of propylene homopolymer, propylene block copolymer I and β-nucleation agent. The melting range of the propylene block copolymer I starts at a temperature ranging from 50 to 120° C. The invention also relates to using the film as a separator in primary or secondary battery.
US08551605B2
A primer-less coating composition for facestock comprises: a binder being a water-dispersible polymer; an ethylenically unsaturated compound which is aqueous-dispersible and miscible with or bonded to said water-dispersible polymer, wherein said ethylenically unsaturated compound is able to form a covalent bond with an ink; and a crosslinker, wherein said crosslinker is suitable for binding the coating to the facestock. The coating composition may be applied to a substrate to form a printable film. A printed film in accordance with the invention may be used in a label, for example for use on a container such as a bottle.
US08551600B2
The present invention is in the field of multiple layer glass panels comprising a polymer sheet having desirable surface properties, and more specifically, the present invention is in the field of multiple layer glass panels comprising poly(vinyl butyral) having a finished surface of relatively low waviness and high roughness disposed in contact with poly(ethylene terephthalate) and/or other poly(vinyl butyral) type layers.
US08551596B2
A self-sticking fabric structure includes loop-like fabric structure, which is fabricated by the yarns of the conjugate fiber and split thereafter to recover smaller fibers, substantially all of the fibers forming loop-like fastening elements between the intersection of interlacing or interlooping, and a hook fabric structure, which is fabricated by the yarns of staple fibers for enabling the ends of the staple fibers to protrude over the surface of the fabric and to form a layer of fiber flock type hook-like fastening elements. The fabrication of the self-sticking fabric does not require any further brushing or pile-raising processing process, saving the manufacturing cost, reducing the fabric thickness, and widening the application of the fabric.
US08551592B2
The two-layered preform includes a tubular body having a mouth providing a neck at a first end thereof and a closed bottom at an opposite second end. At least part of the tubular body is formed by a first layer (P1) made of a primary molding material and a second layer (P2) made of an overmolding material. The first layer (P1) is an inner layer made of a primary molding material providing a barrier effect against light by absorption, and the second layer (P2) is an outer layer made of an overmolding material providing a barrier effect against light by reflection. The neck is formed with the overmolding material of the second layer (P2) not coated by the primary molding material of the first layer (P2).
US08551588B2
A resealable and disposable package assembly is described. The assembly includes a container and a multilayer cover laminate that are bonded to one another to initially seal the contents of the package. The package can then be easily opened by at least partially separating the cover laminate along a predesignated interface. The package can be reliably and effectively sealed by recontacting the previously separated cover portions to one another.
US08551584B2
Transparent ink-jet recording films, compositions, and methods are disclosed. These films can exhibit high maximum optical densities, rapid ink drying, low curl, excellent adhesion between the coating layers and the substrate, and negligible ink transfer between stacked ink-jet recording films after imaging. Such films are useful in medical imaging applications.
US08551568B2
The present invention provides a simple, non-destructive and versatile method that enables layer-by-layer (LbL) assembly to be performed on virtually any substrate. A novel catechol-functionalized polymer which adsorbs to virtually all surfaces and can serve as a platform for LbL assembly in a surface-independent fashion is also provided.
US08551551B2
An omega-3 fatty acid supplementation fat blend includes one part by weight of an omega-3 enriching oil containing EPA and/or DHA fatty acids that has been combined and diluted with at least one-half part by weight of a low linoleic acid content oxidatively stabilizing saturated fat. The omega-3 supplementation fat blend is incorporated into stabilized aqueous suspensions including beverages and foods.
US08551544B2
The various non-limiting embodiments of the present disclosure relate to a protein-based binder or coating system for particulate- and/or powder-type food systems, for example, to form nutritive ready-to-eat food bars, protein bars, snack pieces, or cereal clusters, where the binder comprises a modified wheat protein isolate. Other non-limiting embodiments relate to food compositions comprising a modified wheat protein isolate binder, and at least one of food particulates; powdered food ingredients, such as protein powders; and combinations thereof. In addition, methods for forming the various non-limiting embodiments of the food compositions and the modified wheat protein isolate binder systems are also disclosed.
US08551541B2
The air-refreshing disinfectants currently sold in the market mostly contain artificially synthesized chemical disinfectants. Frequent exposure to the air containing such chemicals may be somewhat harmful to the human body. Therefore the present invention provides an air-refreshing disinfectant, and in particular an air-refreshing disinfectant which is not chemically synthesized and takes natural materials as raw materials and traditional Chinese medicinal volatile oils as main effective ingredients. It is characterized by bacteriostatic and antiviral effects, long-lasting fragrance and cost-effectiveness, and is beneficial to human health. To achieve this objective, the present invention, by taking advantage of the bacteriostatic, antiviral and fragrant characteristics of traditional Chinese medicinal volatile oils, employs specific combinations of eucalyptus oil, clove oil, patchouli oil, forsythia oil and schizonepeta oil as the active ingredients of the air-refreshing disinfectant.
US08551540B1
A stabilizing and antioxidant composition is prepared from the residue obtained from the saw palmetto berry. The residue from the saw palmetto berry exhibits antioxidant properties that can be used to stabilize various compositions such as food or edible compositions and cosmetics. The saw palmetto residue is also delivered topically or orally to a patient to administer an effective amount of an antioxidant to a patient.
US08551539B1
The present invention relates to herbal medicinal compositions and extracts thereof for inhibiting growth of cancer cells. One of the examples described in the present invention comprises Forsythiae fructus, Menthae Herba, Gardeniae Fructus, Scutellariae Radix, Lophatheri Folium, Glycyrrhizae Radix, Rhei Rhizoma, Na2SO4, and Atractylodis Rhizoma. The residual examples are described herein.
US08551533B2
An adjuvant composition is provided which comprises: (a) at least one water-soluble electrolyte; (b) at least one electrolyte-tolerant surfactant; (c) antifoam component which is at least one mixture selected from the group consisting of (1) at least one branched silicone resin (i), at least one silicone fluid (ii), at least one particulate metal oxide (iii) and, optionally, at least one catalyst (iv) for catalyzing the condensation of siloxy groups, (2) the equilibration reaction product of mixture (1), and (3) mixture (1) in which at least a portion of particulate metal oxide (iii) is pre-hydrophobized; (d) optionally, at least one additional bioinert material; and, (e) water.
US08551512B2
Methods for making coatings on an implantable device such as a drug-eluting stent comprising a polymer and nano or microparticles of a drug in slow-dissolving polymorph, implantable devices produced by the methods and methods of using the coatings are provided.
US08551507B2
Several terpene glycosides (e.g., mogroside V, paenoiflorin, geniposide, rubusoside, rebaudioside A, steviol monoside and stevioside) were discovered to enhance the solubility of a number of pharmaceutically and medicinally important compounds, including but not limited to, paclitaxel, camptothecin, curcumin, tanshinone HA, capsaicin, cyclosporine, erythromycin, nystatin, itraconazole, celecoxib, clofazimine, digoxin, oleandrin, nifedipine, and amiodarone. The use of the diterpene glycoside rubusoside and monoterpene glycoside paenoiflorin increased solubility in all tested compounds. The terpene glycosides are a naturally occurring class of water solubility-enhancing compounds that are non-toxic and that will be useful as new complexing agents or excipients in the pharmaceutical, agricultural (e.g., solubilizing pesticides), cosmetic and food industries.
US08551506B2
Certain embodiments disclosed herein relate to compositions, methods, devices, systems, and products regarding frozen particles. In certain embodiments, the frozen particles include materials at low temperatures. In certain embodiments, the frozen particles provide vehicles for delivery of particular agents. In certain embodiments, the frozen particles are administered to at least one biological tissue.
US08551505B2
Certain embodiments disclosed herein relate to compositions, methods, devices, systems, and products regarding frozen particles. In certain embodiments, the frozen particles include materials at low temperatures. In certain embodiments, the frozen particles provide vehicles for delivery of particular agents. In certain embodiments, the frozen particles are administered to at least one biological tissue.
US08551499B2
A method of inducing latency in Mycobacterium permits preparation of an in vitro model system of latent mycobacterial infection. Latency is induced in a pure culture of Mycobacterium by exposing it to multiple stress conditions, including a low nutrient culture medium without glycerol, a low pH, a relatively high level of carbon dioxide and a relatively low gas phase oxygen level. An in vitro model of mycobacterial infection employs macrophages induced from THP1 cells which are then infected with Mycobacterium. The infected macrophages are grown under hypoxic conditions to induce latency in the mycobacteria. The in vitro model of infection is useful in evaluating compounds for activity against latent mycobacteria.
US08551497B2
The present invention includes cold-adapted, acid-fast bacterium for use as a vaccine and a vaccine vector. In preferred embodiments, the cold-adapted, acid-fast bacterium is a Mycobacteria, for example, Mycobacteria shottsii.
US08551495B2
The present invention pertains to the field of immunology and genetic engineering. In particular, the present invention relates to the construction, preparation and use of a recombinant vaccine against foot-and-mouth disease virus. The vaccine comprises a tandem repeat of an antigenic epitope of FMDV VP1 protein, the constant region of the immunoglobulin heavy chain or a functional fragment thereof, and the FMDV 3D protein or an immunogenic fragment thereof. The vaccine can induce protective immune response against FMDV in an animal.
US08551492B2
The present invention relates to compositions comprising peptides for preventing or treating allergy to cats, and in particular to optimal combinations of peptides.
US08551490B2
The invention relates to the identification of genetic products that are expressed in association with a tumor and the nucleic acid coding therefor. The invention relates to the therapy and diagnosis of diseases in which the genetic products that are expressed in association with a tumor are expressed in an aberrant manner. The invention also relates to proteins, polypeptides, and peptides which are expressed in association with a tumor and the nucleic acids coding therefor.
US08551480B2
The present invention concerns methods and compositions for forming immunotoxin complexes having a high efficacy and low systemic toxicity. In preferred embodiments, the toxin moiety is a ranpirnase (Rap), such as Rap(Q). In more preferred embodiments, the immunotoxin is made using dock-and-lock (DNL) technology. The immunotoxin exhibits improved pharmacokinetics, with a longer serum half-life and significantly greater efficacy compared to toxin alone, antibody alone, unconjugated toxin plus antibody or even other types of toxin-antibody constructs. In a most preferred embodiment the construct comprises an anti-Trop-2 antibody conjugated to Rap, although other combinations of antibodies, antibody fragments and toxins may be used to form the subject immunotoxins. The immunotoxins are of use to treat a variety of diseases, such as cancer, autoimmune disease or immune dysfunction.
US08551471B2
The present invention relates to amoebae (slime molds) and uses thereof. In particular, the present invention relates to the use of amoebae or their environmentally stable spores to treat microbial infections and other uses.
US08551464B2
Provided is a method for styling mammalian hair that includes contacting the hair with a composition that includes a poly(vinylamine-vinylformamide) copolymer and a first carrier, contacting the hair with a composition that includes a bisulfite and a second carrier, and styling the hair. The method of the present invention promotes improved hair styling properties such as improved curl retention and straightness retention, e.g., under conditions of high relative humidity and temperature. The method can be used for semi-permanently straightening or curling the hair. Also provided is a method for controlling fizz by applying the copolymer and bisulfite compositions.
US08551461B2
An emulsion lip composition, in solid or stick form, comprising: (a) a reaction product of (i) at least one polyamine with (ii) an oil-soluble polar modified polymer comprising at least one C2-C20 monomer; (b) water; (c) at least one non-volatile solvent; and (d) at least one colorant; and a method of using thereof.
US08551458B2
The invention relates to a composition in the form of an oil-in-water emulsion containing an ester of fatty acid and of polyethylene glycol, an additional surfactant chosen from esters of C16-C22 fatty acid and of sorbitan and esters of C16-C22 fatty acid and of glycerol, a polycondensate of ethylene oxide and of propylene oxide consisting of polyethylene glycol and polypropylene glycol blocks, and a hydroxylated diphenylmethane derivative. The composition has good stability, in particular after 24 hours at 55° C. Application in caring for and making up keratinous substances.
US08551454B2
Disclosed herein are vials and devices containing a ketorolac solution for intranasal administration and a head space comprising no more than about 10% v/v oxygen and which vials and devices are stored in an oxygen-impermeable pouch. Also disclosed are processes for preparing the vials and devices.
US08551450B2
Peptide vectors having high KDR binding affinity and processes for making such vectors are provided. The peptide vectors may be conjugated to phospholipids and included in ultrasound contrast agent compositions. Such ultrasound contrast agents are particularly useful in therapeutic and diagnostic methods, such as in imaging KDR-containing tissue and in the evaluation and treatment of angiogenic processes associated with neoplastic conditions. The present invention also provides processes for the large scale production of highly pure dimeric and monomeric peptide phospholipid conjugates as well as precursor materials used to form the conjugates. The present invention further provides processes for the large scale production of highly pure peptide phospholipid conjugates which contain very low levels of TFA.
US08551447B2
A bifunctional compound with a monosaccharide and a N2S2 ligand, and more particularly, a bifunctional compound with a N2S2 ligand and aminohexylacetyl galactosamine (ah-GalNAc4) is provided. A method for preparing the bifunctional compound with a monosaccharide and a N2S2 ligand is also provided, including activating a carboxyl group in an organic ligand, reacting the activated carboxyl group with a galactopyranoside through amidation, and then hydrolyzing. The bifunctional compound of the present invention is widely useful in nuclear medicine for preparation of liver imaging agents for assisting in correct diagnosis of diseases.
US08551446B2
A coating for a medical device, particularly for a drug eluting stent, is described. The coating includes a polyacetal-based polymer.
US08551442B2
A reactor for synthesizing hydrogen sulfide in which sulfur and hydrogen are subjected to gas-phase reaction in the absence of a catalyst to synthesize hydrogen sulfide, the reactor including: a reactor body that retains liquid sulfur in a bottom portion thereof; a heating unit that gasifies part of the liquid sulfur; a hydrogen gas supply unit that supplies hydrogen gas into the liquid sulfur; and a heat-exchanging portion provided in a gas-phase reaction region located above the liquid surface of the liquid sulfur in the reactor body, wherein heat-exchanging portion is configured such that the reaction temperature in the gas-phase reaction region is controlled to be within a predetermined temperature range by changing the heat exchange amount per unit volume in a gas-phase reaction region located farther from the liquid surface from the heat exchange amount per unit volume in a gas-phase reaction region located closer to the liquid surface.
US08551441B1
New methods for improving thermoelectric properties of bismuth telluride based materials are described. Constrained deformation, such as by canned/sandwich, or encapsulated, rolling and plane strain channel die compression, particularly at temperatures above 80% of the melting point of the material on an absolute temperature scale, changes the crystallographic texture and grain size to desirably increase the values of both the thermoelectric power factor and the thermoelectric figure of merit ZT for the material.
US08551439B2
A method of refining carbon parts for the production of polycrystalline silicon, comprises the steps of, replacing an inside gas of a reactor, in which the carbon parts are placed, with an inert gas, drying the carbon parts by raising a temperature in the reactor to a drying temperature of the carbon parts while flowing an inert gas through the reactor, raising a temperature in the reactor to a purification temperature higher than the drying temperature while flowing chlorine gas through the reactor, reducing a pressure in the reactor, maintaining the inside of the reactor in a reduced pressure, pressurizing the inside of the reactor by introducing chlorine gas for bringing the inside of the reactor into a pressurized state, and cooling the inside of the reactor.
US08551433B2
A SCR catalyst system, comprising a first SCR catalyst (1) and a second SCR catalyst (2) which is disposed in the exhaust gas tract downstream of the first SCR catalyst (1). At least one metering device (12) for metering in a reducing agent solution is disposed in the exhaust gas tract upstream of a first SCR catalysis element (13) of said first SCR catalyst (1). The SCR catalyst system does not require a device for metering a reducing agent solution into a second SCR catalysis element (21) of the second SCR catalyst (2).
US08551425B2
The present invention provides a method for diagnosing cancer, predicting a disease outcome or response to therapy in a patient sample. The method involves isolating a circulating tumor cell (CTC), for example, a viable CTC, from a sample using a parylene microfilter device comprising a membrane filter having or consisting of a parylene substrate, which has an array of holes with a predetermined shape and size; and detecting and quantifying telomerase activity in blood circulating tumor cells. The invention further provides methods of using cells live-captured in various applications.
US08551422B2
Analytical cartridges, systems and methods of processing a sample for analysis using capillary flows. Vertical gradient sample filtration provides filtrate to an incubation chamber for a time controlled by a flow modulator at the outlet of the incubation chamber. The flow modulator can include a serpentine capillary flow path without side walls. Incubated filtrate can flow from the incubation chamber to a detection channel after a predetermined time. The detection chamber can include one or more analytical regions in a porous substrate for detection of two or more analytes on the same cartridge from the same sample.
US08551421B2
A laboratory instrument for the preparation of samples includes a base housing with a work compartment enclosed by protective walls, at least one multifunctional work head having the ability to turn about a rotary axis pivotally supported on the base housing. At least two defined functional positions that can be aligned with at least one container platform which is arranged in the work compartment. The first functional position contains a receiving device which serves to hold a dosage-dispensing device with free-flowing dosage material, and each of the other functional positions contains an additional device. At least one of the protective walls has a cutout opening, and the at least one multifunctional work head is arranged partially in the cutout, so that portions of the at least one multifunctional work head lies both inside and outside of the work compartment.
US08551415B2
Methods and apparatus for the removal of exhaust gases are provided herein. In some embodiments, an exhaust apparatus may include a housing defining an inner volume; an inlet and an outlet formed in the housing to facilitate flow of an exhaust gas through the inner volume, wherein the inlet is configured to be coupled to a process chamber to receive an exhaust therefrom; and an ultraviolet light source to provide ultraviolet energy to the inner volume. The ultraviolet light source may provide sufficient energy to at least partially decompose the exhaust gases. In some embodiments, the ultraviolet light source may provide ultraviolet energy until the exhaust gas has cooled below a critical temperature.
US08551403B2
A combinatorial chemical formation and assay disc (1) having a base (20) and an upper surface (26) and a lower surface, one of the upper or lower surfaces being an assay surface and a data surface (40) spaced from the assay surface wherein the data surface is on or within the assay disc. The assay surface has a conductive layer (64) on the base, a dielectric or photo-conductive layer (66) on the conductive layer and a chemically functional layer (68, 69) on the dielectric or photo-conductive layer. The assay surface may be planar or include three dimensional features (100, 168).
US08551402B1
A self-contained, mobile assay facility built in a modified armored truck is completely equipped to melt and assay precious metals, particularly gold and silver. An induction furnace melts the metal that is then poured into an ingot. The ingot is weighed and analyzed using an XRF alloy analyzer and the percentage of gold and/or other metals recorded. The value of the gold at current market prices is calculated and the assay and the value of the ingot is printed and given to the seller. The seller may opt to receive the ingot and pay the assayer an assay fee. Alternately, the seller may ask to be paid cash, by bullion, wire transfer, or by an open hedge. Either a transfer or hedge is initiated and confirmed from the assay facility. The ingots may be safely stored or shipped directly from the mobile facility to a wholesaler for further processing.
US08551398B1
An apparatus for reducing the spread of infection includes a covering that is placed over a handle. A quantity of disinfectant that is disposed in an interior portion of the apparatus is expelled from the interior portion to an exterior surface of the apparatus when a user grasps and squeezes the covering or by gravity or by the use of a pump. The pump is activated at regular intervals or when the approach of a user is detected. The disinfectant is replenished or the apparatus is periodically replaced if an interior reservoir is used. If an outer reservoir is used the disinfectant is replenished or the reservoir is periodically replaced. A method for applying a disinfectant to an exterior surface of a covering is provided. According to a modification, the disinfectant is conveyed from the outer reservoir to an exterior surface of the handle by activation of the pump or by gravity if the reservoir is elevated above the handle. A method for applying a disinfectant to an exterior surface of a handle is provided.
US08551397B2
The invention relates to a manufacturing process for steel blanks. The invention relates in particular to a manufacturing process of a steel blank comprising electroslag remelting (ESR—ElectroSlag Remelting) or vacuum arc remelting (VAR—Vacuum Arc Remelting) to obtain very good mechanical properties. The blanks obtained can be used especially in the field of the manufacture of pressurized equipment elements and especially cannon tubes.
US08551392B2
A method for manufacturing a transmission electron microscope (TEM) micro-grid is provided. A sheet of carbon nanotube structure comprising a plurality of carbon nanotubes is first provided. Some carbon nanotubes are removed from selected portions of the sheet of carbon nanotube structure to form a plurality of electron transmission portions. Each of the electron transmission portions includes a hole defined in the sheet of carbon nanotube structure and a plurality of residual carbon nanotubes in the hole. The sheet of carbon nanotube structure having the electron transmission portions is cut into pieces to form the TEM micro-grid.
US08551389B2
A method is disclosed for manufacturing an anisotropic material comprising providing a viscoplastic material having a yield stress, and a plurality of magnetic particles disposed therein, and then subjecting the viscoplastic material to a magnetic field for a time sufficient to at least partially align at least a portion of the magnetic particles to at least one of a predetermined position or orientation. Also disclosed is an article having anisotropic properties comprising a viscoplastic material, and a plurality of magnetic particles distributed therein and at least partially aligned to a predetermined orientation. An article having anisotropic properties, comprising a fixed viscoplastic material, and a plurality of magnetic particles distributed and at least partially anisotropically aligned in the fixed viscoplastic material is disclosed.
US08551388B2
The present invention relates to a process for fabricating a quadrupole mass spectrometer (QMS) component, to a monolithic quadrupole mass spectrometer or a component thereof, to a quadrupole mass filter (QMF) or quadrupole ion trap (QIT) capable of generating a hyperbolic electric field and to a modular quadrupole mass spectrometer (QMS) assembly.
US08551386B2
Methods for imparting a texture to a cured powder coated surface are provided. These methods involve heating the cured powder coating to a temperature greater than its glass transition point (Tg), then imparting a texture to the cured powder coating under pressure using a release medium having a replicative surface. After the texture is imparted to the cured powder coating, the release medium can be removed. Examples of suitable release media include, for example, engraved plates, engraved rolls, release papers, release films, and release webs.
US08551381B2
A fiber composite component comprising at least two, first and second partial elements bordering one another, each having a fiber structure and different matrix systems which respectively embed the fiber structure and cure differently from a liquid state is produced by liquifying the matrix system of the first partial element so that it either penetrates irregularly into the region of the bordering second partial element or leaves an unwetted region in the first partial element adjacent the second partial element, and subsequently liquifying the matrix system of the second partial element so that it can be cured abutting the irregular boundary surfaces of the matrix system of the first partial element. The intermeshing or interlocking of the matrix systems with one another and the fibers increase shear strength.
US08551380B2
Composite prepreg is laid up over a tool by placing prepreg material on a carrier film and using the carrier film to apply the prepreg material to the tool. The prepreg is conformed to contours of the tool by deforming the carrier film.
US08551379B2
A method and system is provided for forming a three-dimensional image and, more particularly, for making three-dimensional digital image transfer thermoformed objects on, e.g., generic molds. The method includes manipulating digital images of a subject into a single image; printing the single image onto a media; and thermoforming the media with the single image using a generic mold. The system comprises a computer infrastructure operable to: receive images of a subject; display the images; stitch together the images to form a single image; adjust portions of the images or single image to compensate for deformation during thermoforming of the single image; register the single image with points on a mold; and print the single image.
US08551370B2
An oxide sintered body substantially containing zinc, tin and oxygen; containing tin at an atomic number ratio, Sn/(Zn+Sn), of 0.23 to 0.50, and being composed mainly of a zinc oxide phase and at least one kind of zinc stannate compound phase, or being composed of at least one kind of zinc stannate compound phase; provided by a method for manufacturing the oxide sintered body by formulating an aqueous solvent to raw material powder containing powder of a zinc stannate compound, or mixed powder of tin oxide powder and zinc oxide powder, and after mixing the resulting slurry for equal to longer than 15 hours, by subjecting the slurry to solid-liquid separation, drying and granulation and subsequently compacting by charging the granule into a mold followed by sintering the resultant compact under sintering atmosphere at 1300 to 1500° C. for equal to or longer than 15 hours.
US08551365B2
An additive formulation suitable for antistatic modification and improving the electrical conductivity of inanimate organic material, consisting essentially of (A) from 1 to 50% by weight of an olefin-sulfur dioxide copolymer, (B) from 1 to 50% by weight of a compound which comprises one or more basic nitrogen atoms and has at least one relatively long-chain linear or branched hydrocarbon radical having at least four carbon atoms or an equivalent structural element which ensures the solubility of component (B) in the inanimate organic material, (C) from 0.1 to 30% by weight of an oil-soluble acid and (D) from 1 to 80% by weight of a high-boiling organic solvent which consists of one or more molecule types, where at least 80% by weight of these molecule types have a boiling point of more than 150° C. at standard pressure, where the sum of all components adds up to 100% by weight.
US08551360B2
The invention relates to a method of manufacturing a rare-earth doped alkaline-earth silicon nitride phosphor of a stoichiometric composition. Said method comprising the step of selecting one or more compounds each comprising at least one element of the group comprising the rare-earth elements (RE), the alkaline-earth elements (AE), silicon (Si) and nitrogen (N) and together comprising the necessary elements to form the rare-earth doped alkaline-earth silicon nitride phosphor (AE2Si5N8:RE). The method further comprises the step of bringing the compounds at an elevated temperature in reaction for forming the rare-earth doped alkaline-earth silicon nitride phosphor (AE2Si5N8:RE). In such a method normally a small amount of oxygen, whether intentionally or not-intentionally added, will be incorporated in the rare-earth doped alkaline-earth silicon nitride phosphor (AE2Si5N8:RE). According to the invention the creation of defects by formation of a non-stoichiometric oxygen containing phosphor is at least partly prevented by partly substituting for the ions (AE, Si, N) of the alkaline-earth silicon nitride phosphor (AE2Si5N8:RE) suitable further elements of the periodic system by which vacancies are created, filled or annihilated resulting in the formation of a modified alkaline-earth silicon nitride phosphor (AE2Si5N8:RE) having a stoichiometric composition. In this way a modified phosphor is obtained having excellent and stable optical properties. The invention further relates to a modified phosphor obtainable by the above-mentioned method and a radiation converting device comprising such a phosphor.
US08551359B2
The present invention relates to liquid-crystalline compounds having two fluorinated biphenyl units, a terminal trifluoromethyl or trifluoromethoxy group and a —CF2O— bridge between the two fluorinated biphenyl units. The invention also relates to liquid-crystalline media prepared therewith and to liquid-crystal display devices (LC displays) containing these media.
US08551357B2
There is provided a method for manufacturing a thin polarizing film having an absorption axis oblique to a width direction of the film which comprises the steps of: performing an orientation treatment in two directions in a plane of a support film; applying a solution containing a lyotropic liquid crystal compound onto a surface of the support film; and causing a column-shaped aggregate of the lyotropic liquid crystal compound to be oriented in a direction (orientation direction) equal to the vector sum of a direction of first orientation treatment and a direction of second orientation treatment.
US08551356B2
An granular composition for absorbing liquids, the composition comprising perlite, super-absorbent polymer, a pH-indicating dye, and a minor amount of water. According to one preferred embodiment of the invention, the subject composition comprises about 80 weight percent perlite, about 5 weight percent SAP, about 0.0125 weight percent pH indicating dye (most preferably phenolphthalein), and from about 7 to about 9 weight percent water in the final product.
US08551351B2
A nozzle plate has a nozzle hole for ejecting liquid, which penetrates in a thickness direction of the nozzle plate. An ejection face of the nozzle plate having an ejection opening of the nozzle hole is covered with a water-repellent coat having a through hole communicating with the nozzle hole. The through hole has a straight portion and a diameter expansion portion. The straight portion is contiguous to the nozzle hole and having the same diameter as the ejection opening. The diameter expansion portion is provided to interpose the straight portion with the nozzle hole and gradually expanding so that a part thereof farther from the straight portion has a larger diameter than a part thereof closer to the straight portion.
US08551346B2
A photomask-forming glass substrate having a square major surface is provided wherein two strip regions are defined on the major surface near a pair of opposed sides such that each region spans between 2 mm and 10 mm inward of the side and excludes end portions extending 2 mm inward from the opposed ends of the side, a least squares plane is computed for each of the two strip regions, the angle included between normal lines to the least squares planes of two strip regions is within 10 seconds, and the height difference between two strip regions is up to 0.5 μm.
US08551332B2
The present invention is affinity particles that are characterized by having phosphorylcholine groups represented by the following formula (1) covalently bonded onto the surface of inorganic powder and also by having ligands having specific affinity with a certain target substance covalently bonded or adsorbed onto the surface of inorganic powder.The object of the present invention is to provide an affinity separation method that uses affinity particles utilizing inexpensive inorganic particles and is capable of separating the target substance easily and with high accuracy.
US08551328B2
Chemically combined chlorides are removed from intermediate and product streams of a hydrocarbon reforming process by contacting the streams with zeolite 13X, having a Si/Al ratio of less than 1.25.
US08551327B2
Processes are provided for producing a diesel fuel product having a sulfur content of 10 ppm by weight or less from feed sources that include up to 20% by weight of a biocomponent feedstock. The mineral hydrocarbon portions of the feed sources can be distillate or heavier feed sources.
US08551324B2
The present invention describes a process for the production of gasoline in a fluid catalytic cracking unit having at least one principal reactor operating using feeds with a low Conradson Carbon and a high hydrogen content, said process comprising recycling a coking cut either to a side chamber branching off the stripper or within the stripper itself by means of a tubular vessel within said stripper.
US08551318B2
Apparatus and method for detecting current or potential generated in a liquid sample suitable for use in a chromatography or other liquid sample analytical system. One embodiment is an electrolytic ion transfer device with a signal detector in communication with the electrodes of the transfer device. Another is a combination ion transfer device/electrolyte generator. Another substitutes a detector for the ion transfer device in the combination.
US08551306B2
A permanent cathode that is to be used as electrode in the electro-refining and/or recovery of metals, such as copper, zinc, cobalt or nickel. The permanent cathode comprises a planar mother plate that is made of metal and comprises two sides. The mother plate comprises an edge, which at least partly surrounds the metal plate. The edge comprises a groove portion that is provided with a groove. The groove portion comprises at least one bridging section for joining together, over the groove portion of the edge of the metal plate at the at least one bridging section, the cathode metal halves, such as cathode copper halves, cathode zinc halves, cathode cobalt halves or cathode nickel halves, which are formed on the sides of the mother plate in the electro-refining of the metals.
US08551300B2
A coated article, and a corresponding method of making the same are provided. The coated article includes a coating supported by a substrate, the coating including a thin metal or metal nitride contact layer (e.g., NiCr, Ni, Cr, CrNx or NiCrNx) located directly between and contacting an infrared (IR) reflecting layer (e.g., Ag) and an oxide barrier layer (e.g., NiCrOx).
US08551299B2
A method of producing HCl from H2 and Cl2 is provided. In some embodiments, the method comprises at least one photochemical chamber placed in fluid communication with at least one source of H2 and at least one source of Cl2. In some embodiments, the photochemical chamber effects the formation of HCl through the use of at least one source of ultraviolet radiation contained therein. In some embodiments, the HCl product may be captured and used as a gas. In some embodiments, the HCl product may be absorbed into water to form an aqueous HCl solution.
US08551297B2
A process for extractive distillation, including: feeding a solvent to an extractive distillation column via a solvent feeding inlet, wherein the solvent has a feeding temperature 3.5˜22.5° C. higher than a top temperature of the extractive distillation column; feeding a mixture comprising a light component and a heavy component to the extractive distillation column via a mixture feeding inlet, wherein the light and heavy components are according to the volatility after adding the solvent, wherein the mixture is liquid, and the mixture feeding inlet is lower than the solvent feeding inlet; condensing a vapor generated by the mixture in an upper portion of the extractive distillation column to obtain the light component; and separating the solvent in a lower portion of the extractive distillation column to obtain the heavy component.
US08551295B2
A reactive distillation apparatus for multistage counter-current rotating bed includes a closed shell, in the center of which a revolving shaft linking each shell section is set, the shaft is provided with two or more rotors in series connection, a feeding inlet, a reflux inlet and an outlet of the gas phase are mounted on the top end face of the shell while a waste liquid outlet and an inlet of the gas phase are set on the bottom end face of the shell, a group of concentric dynamic filler rings with different diameters are installed at intervals along the radial direction, wherein the wall of the dynamic filler rings is holed, and the ring clearance between the dynamic filler rings is configured with static rings fastened on the static disc; a feeding inlet is arranged on the top cover of the shell corresponding to the spray nozzle of raw material liquid; a rotating liquid distributor is arranged on the inner side of the innermost dynamic filler ring of the said lower rotor.
US08551293B2
An improved method for producing paper from pulp includes a plurality of subassemblies arranged in the forming or wet section of a Fourdrinier. The Fourdrinier includes a dewatering table having a plurality of blades that are static and on-the run adjustable in height and/or angle to control orientation of paper fibers in the stock to create a superior quality of paper and improved paper strength characteristics. Gravity and vacuum assisted drainage elements are equipped with on-the-run adjustable angle and height dewatering foil blades starting from a paper dryness of 0.1% and extending all the way to 5% dryness. The result of this process and machine is to improve the paper quality, save fibers and chemicals and fulfill the required paper properties.
US08551284B2
The invention provides a polarizing film comprising: a long polymer film; and a dichroic substance, wherein the polarizing film has an absorption axis in the TD direction of the polarizing film.
US08551280B2
A panel includes a fiberglass substrate encapsulating an aesthetic material. The fiberglass substrate and the aesthetic material are both impregnated with resin to form the solid-core of the panel. The solid-core panel can be manufactured by arranging multiple layers of a fiberglass material between multiple plates, interleaving aesthetic material between at least two of the layers of fiberglass material, applying resin to the multiple layers of fiberglass material and the aesthetic material, and then allowing the combination of the resin, multiple layers of fiberglass material, and the aesthetic material to cure between the plates, forming a solid-core panel encapsulating the aesthetic material.
US08551276B2
A laminating process in which an adhesive composition which is freely flowing or can be rendered freely flowing is discharged from a coating appliance in the form of a substantially continuous or interrupted film, out of a slot nozzle with lateral film boundaries, and is applied and fixed to the surface of at least one web-type substrate, if applicable after being deposited on an advancing transfer substrate, such as a roller, and then transferred to the web-type substrate, and in which the film is guided outward to the substrate via the nozzle slot, clamped or hemmed in at its edges by the film boundary elements, heat is drawn off to the surrounding atmosphere via at least one heat exchange element provided along the film boundary elements.
US08551273B2
The present invention relates to a method for forming fluoroplastic articles including inner and outer fluoroplastic layers and a metal meshwork, the metal meshwork being arranged between the inner and outer fluoroplastic layers, characterized by the meshwork being stretchable and compressible in an axial direction.
US08551269B2
A method for controlling a labelling device, that is part of a block system including a supply device for supplying articles to be labeled, includes supplying, by the supply device, a predetermined number of the articles such that the labelling device and the supply device are each operated at a first operating speed. The predetermined number of the articles are delivered, in an automated manner, to the labelling device. A drive of the labelling device is decoupled from a corresponding drive of the supply device. The labelling device is then operated at a second operating speed.
US08551262B2
A method of maintaining a floor comprises discharging a diluting fluid from a first reservoir to a mixing apparatus, discharging a cleaner concentrate from a second reservoir to the mixing apparatus, continuously identifying changes in fluid level within the first reservoir with a level sensor, providing a first signal indicative of an identified change in fluid level, passing the cleaner concentrate and diluting fluid through a flow control device, and processing the first signal to generate an output signal and controlling operation of the pump and the flow control device in response to the output signal to provide a flow of fluid to a cleaning device at a substantially constant ratio of the diluting fluid from the first reservoir to the cleaner concentrate from the second reservoir for substantially all fluid levels of the first reservoir.
US08551255B2
A dishwasher includes a first washing chamber and a second washing chamber capable of performing a washing operation separately and/or concurrently. Each washing chamber includes a wash pump, a drain pump and a heating unit that are operatively connected to a controller. When initiating a washing fluid in one washing chamber, the controller determines if the other washing chamber is active. If the other washing chamber is active, the heating unit for the one washing chamber is operated at a low power level. However, if the other washing chamber is inactive, the one washing chamber is operated at a high power level to rapidly heat the washing fluid and thus shorten the duration of the washing operation.
US08551254B2
In embodiments of the present invention, a gutter-cleaning device comprises a housing containing an impeller drive facility, the housing configured to fit into a gutter, an impeller, disposed at an end of the housing and driven by the impeller drive facility, and a transport facility for transporting the housing along the gutter.
US08551252B2
Methods for removing residual particles from a substrate are presented including: receiving the substrate including the residual particles; and functionalizing the residual particles with functionalizing molecules, wherein the functionalizing molecules selectively attach with a surface the residual particles, where the functionalizing molecules impart a changed chemical characteristic to the residual particles, and where the changed chemical characteristic facilitates removal of the residual particles from the substrate. In some embodiments, methods further include: before functionalizing, cleaning the substrate, where the cleaning leaves residual particles adhered with a surface of the substrate, and where the residual particles are hydrophilic; and if the surface of the substrate is hydrophobic, performing the functionalizing. In some embodiments, methods further include removing the residual particles from the surface of the substrate where removing the residual particles includes removing the functionalizing molecules.
US08551251B2
Improved methods and apparatus for cleaning substrates and enhancing diffusion limited reaction at substrate surfaces use piezoelectric transducers operating in the gigasonic domain. The resonator assemblies include plural transducer stacks each including a thin film piezoelectric element coupled to a resonator plate that faces the substrate. At the disclosed frequencies and powers used, Eckart or Rayleigh streaming can be induced in a liquid treatment medium without substantial generation of cavitation.
US08551250B2
The present invention relates to a method of extracting a carbohydrate from a carbohydrate juice, said method comprising the steps of: a) providing an adsorbent having unsaturated hydrocarbon groups exposed on its surface wherein said groups are capable of adsorbing a carbohydrate to the (internal) surface of the adsorbent by CH/p interaction, and optionally in addition by hydrogen bonding; b) contacting said raw carbohydrate juice with said adsorbent under conditions by which said carbohydrate is adsorbed to said adsorbent by CH/p interaction, and c) desorbing said carbohydrate from said adsorbent by increasing the temperature of the carbohydrate-adsorbent complex.
US08551247B2
Controlling crystal growth in a crystal growing system is described. The crystal growing system includes a heated crucible including a semiconductor melt from which a monocrystalline ingot is grown according to a Czochralski and the ingot is grown on a seed crystal pulled from the melt. The method includes applying a cusped magnetic field to the melt by supplying an upper coil with a first direct current (IUDC) and supplying a lower coil with a second direct current (ILDC). The method also includes supplying the upper coil with a first alternating current (IUAC) and supplying the lower coil with a second alternating current (ILAC) to generate a time-varying magnetic field, wherein the time-varying magnetic field generates a pumping force in the semiconductor melt.
US08551244B2
A self-adaptive cement system includes cement, water and at least one additive that reacts or/and expands in contact with oil and gas. Several chemical products have been identified including rubber alkylstyrene, polynorbornene, resins such precrosslinked substituted vinyl acrylate copolymers and diatomaceous earth. These additives have the effect of making the cement self-healing in the event of physical failure or damage such as micro-annuli. The self healing property is produced by the contact with subterranean hydrocarbon fluids, the potential repair mechanism is thus activated if and when needed in case of start of loss of zonal isolation. In another embodiment, the expansion is deliberately induced by pumping a hydrocarbon fluid in the vicinity of the set cement.
US08551243B2
Concrete reinforced with nanostructures and reinforcing concrete methods are provided having cement and dispersion including water, a surfactant, carbon nanotubes having on the external surfaces thereof carbon atoms substituted by atoms of another element or other elements, and carbon nanotubes possessing chemical groups on the surface thereof.
US08551241B2
A method of making a rapid setting lightweight cementitious composition with improved compressive strength for products such as boards is disclosed. The method mixes fly ash, alkali metal salt of citric acid and lightweight aggregate with water. Compositions which include fly ash, alkali metal salts of citric acid and lightweight aggregate are also disclosed.
US08551237B2
A process for preparing colorants of the general formula (Ia), (Ib) or (Ic) or mixtures thereof, comprises reacting (a) tetracarboxylic acids or their functional derivatives with (b) at least one compound selected from i. aliphatic amines, ii. aromatic amines, iii. aliphatic diamines, iv. aromatic diamines, (c) optionally in the presence of further additives, (d) optionally in the presence of wetting agents in a mixing apparatus. These colorants are useful for coloration of macromolecular organic and inorganic materials of natural and synthetic origin.
US08551234B2
An air cleaner having a manipulator is disclosed. The manipulator (200) includes a rotary manipulation unit (300), which is provided so as to be movable between a first position, at which the rotary manipulation unit is retracted into the air cleaner, and a second position, to which the rotary manipulation unit is extracted from the air cleaner to enable a user to manipulate the rotary manipulation unit. The manipulator further includes a lift unit (400), which is installed in the air cleaner to move the rotary manipulation unit between the first position and the second position. In the present invention, the manipulator can control several functions of the air cleaner obviating the need for having several control buttons, thus being more convenient for a user. Furthermore, the present invention can prevent water from permeating a PCB mounted in the rotary manipulation unit, thus preventing malfunction of the encoder unit.
US08551221B2
Carbon Dioxide capture processes utilizing ammonia, or ammonia in water as the capture fluid for carbon dioxide generate concentrated solutions of ammonium carbonate species in water, which are subsequently decomposed to capture the carbon dioxide and recycle the ammonia. Forward osmosis processes utilize ammonium carbonate species as draw solutions to pull water from saline solutions such as seawater in the ammonium carbonate solution. The ammonium carbonate solution is then heated to decompose the ammonium carbonate to ammonia and CO2 which are both reused, while a portion of the aqueous stream is recovered as pure water. Combination of carbon capture process with an integrated forward osmosis process provide great economies over standalone operations. Furthermore, the very high concentrations of ammonium carbonate provide a further opportunity to include osmotic power recovery cycles with the integrated forward osmosis and carbon capture process.
US08551218B2
A process for the abatement of carbonyl sulphide, carbon disulphide, metal carbonyl compounds, hydrogen sulphide and hydrogen cyanide, ammonia and arsenic and chlorine compounds from a feed gas comprising the steps of contacting the gas in succession with a first purification agent comprising activated carbon, with a second purification agent comprising alumina, with a third purification agent comprising zinc oxide, with a fourth purification agent comprising a zeolitic material and a fifth purification agent comprising zinc oxide and copper oxide.
US08551216B2
Systems and methods for treating a fluid with a body are disclosed. Various aspects involve treating a fluid with a porous body. In select embodiments, a body comprises ash particles, and the ash particles used to form the body may be selected based on their providing one or more desired properties for a given treatment. Various bodies provide for the reaction and/or removal of a substance in a fluid, often using a porous body comprised of ash particles. Computer-operable methods for matching a source material to an application are disclosed. Certain aspects feature a porous body comprised of ash particles, the ash particles have a particle size distribution and interparticle connectivity that creates a plurality of pores having a pore size distribution and pore connectivity, and the pore size distribution and pore connectivity are such that a first fluid may substantially penetrate the pores.
US08551202B2
The invention provides compositions and methods for planarizing or polishing a substrate. The composition comprises an abrasive, iodate ion, a nitrogen-containing compound selected from the group consisting of a nitrogen-containing C4-20 heterocycle and a C1-20 alkylamine, and a liquid carrier comprising water.
US08551201B2
Polyurethane composition based on a certain polyether and polyester prepolymer reaction mixture, wherein the composition is utilized in manufacturing chemical mechanical polishing/planarizing (CMP) pads. The CMP pads have low rebound and can dissipate irregular energy as well as stabilize polishing to yield improved uniformity and less dishing of the substrate.
US08551199B2
A method of recycling a tail gas includes converting sulfur present in an acid gas stream into elemental sulfur to produce a tail gas and recycling the tail gas to at least one of a gasification reactor and a gas removal subsystem.
US08551197B2
A hydrogen generation system is disclosed that includes an integrated steam reforming reactor. The reactor has an overall cylindrical shape, receives a reformate and separately receiving a combustion gas mixture. The reactor includes a plurality of reforming stages arranged in a stacked series of disc shaped stage configuration, wherein each reforming stage has a disc shaped combustion portion adjacent a disc shaped catalyst pack through which the reformate passes, wherein the reformate is directed axially between stages and radially within each stage; and the combustion mixture is directed radially between groups of stages and circumferentially within each stage.
US08551195B2
A composition and method is disclosed for a wickless semi-liquid candle.
US08551194B2
A candle and process for making it are disclosed. The candle comprises prilled wax particles, comprising hydrogenated natural oil and wherein at least 75% of the prilled wax particles are less than 800 μm in diameter. The candle includes a compressed core and a thermally fused outer layer.
US08551190B2
A method for manufacturing a coloring agent for keratin fibers is provided. The method includes directing a composition A from a container A by a filler apparatus through an inlet opening into a container B containing a composition B. A coloring agent for keratin fibers exits from the container B as a mixture of the composition A and the composition B. The composition A is flowable and encompasses a polymeric thickener and the composition B encompasses a fatty alcohol.
US08551184B1
In one aspect, the invention provides methods and apparatus facilitating an adjustable-stiffness prosthesis or orthosis (including approximations to arbitrarily definable non-linear spring functions). Spring rates may be varied under no-load conditions during a walking gate cycle to minimize power consumption. In another aspect, the invention provides methods and apparatus for outputting positive power from a prosthesis or orthosis, facilitating high-performance artificial limbs. In one embodiment of the invention, the positive power is transferred from a functioning muscle to the prosthesis or orthosis, which mimics or assists a non-functioning or impaired muscle. In another embodiment of the invention, the positive power comes from an on-board power source in the prosthesis or orthosis.
US08551181B2
A trial system for a prosthesis is described. The prosthesis can include an acetabular prosthesis generally for implantation in an acetabulum and the surrounding pelvis. The acetabular prosthesis includes an acetabular cup having a substantially concave inner surface and a substantially convex outer surface. One trial shell or a collection of trial shells are provided to trial a range of motion of the hip joint before implanting a shell prosthesis into the acetabular prosthesis.
US08551178B2
A method for treating arthritis of a joint includes identifying a bone lesion in a bone adjacent to the joint; and implanting in the bone a reinforcing member in or adjacent to the bone lesion. A kit for conducting the method includes: (a) at least one reinforcing member having a proximal face adapted to face the joint, a distal face adapted to face away from the joint, and a wedge-shaped edge adapted to pierce bone, wherein the at least one reinforcing member is planar and sterile; and (b) a container adapted to maintain the at least one reinforcing member sterile. Another kit includes: (a) a sterile fluid; (b) a syringe for injecting the fluid into a bone; (c) a curing agent adapted to cure the fluid to polymerize and/or cross-link; and (d) a container adapted to maintain the sterility of contents of the container.
US08551166B2
A method of deploying an ocular implant into Schlemm's canal of a human eye including the following steps: inserting a distal tip of a delivery tool within an anterior chamber of the eye through trabecular meshwork of the eye into Schlemm's canal of the eye; and advancing an ocular implant through a curved portion and a distal opening of the delivery tool to place a body portion of the ocular implant in Schlemm's canal and an inlet portion of the ocular implant in the anterior chamber.
US08551163B2
A high efficiency cardiac support system is suitable for chronic use in treating heart failure, wherein the system includes an implantable rotary blood pump, an implantable power module, a wireless power transfer subsystem, a patient monitor, and a programmer. In a cardiac support system, the cumulative efficiencies of the components of the system are capable of providing therapeutically effective blood flow for a typical day of awake hours using the energy from a single wireless recharge of an implanted rechargeable energy source. Moreover, the implantable rechargeable energy source may be recharged during a normal sleep period of 8 hours or less. The system may provide full or partial cardiac support without the need for external wearable batteries, controllers, or cables.
US08551155B2
Methods and systems are described for receiving a parameter relating to a specific patient, and for customizing one or more attributes of a stent ex situ as an at-least-roughly contemporaneous response to receiving the parameter relating to the specific patient or for customizing one or more junctions of a stent ex situ in response to the received parameter relating to the specific patient.
US08551141B2
A multi-stage minimally invasive surgical procedure and associated instruments are disclosed. First, the surgical site is prepared. After preparation, the bone screws or anchors are attached to the bone. Subsequent to insertion of the screws, a rod or connecting member is positioned within the yoke portion of the bone screw. Caps are then placed in a pre-lock position within the yokes. The bone screws may be compressed together or distracted along the rod or connecting member, thereby setting the final spacing of the bones or bone segments. Finally the caps are moved to a final lock position to fix the screws to the rod or connecting member to maintain the bones in position relative to each other.
US08551140B2
A method and apparatus for coupling a soft tissue implant into a locking cavity formed within a bone is disclosed. A bone engaging fastener is coupled to bone. A second fastener is coupled to a suture construction. The second fastener is coupled to the first fastener. Soft tissue is coupled to the suture construction.
US08551130B2
The invention provides a system, device and method for localized application of therapeutic substances within a biological conduit. One embodiment comprises a rotational atherectomy device having a flexible, elongated, rotatable, drive shaft having a lumen and with an eccentric enlarged abrading head having at least one application hole attached therethrough and in communication with a therapeutic agent delivery sheath and an operator-controlled actuator. The therapeutic substances may then spray radially outwardly from the application hole(s) on the eccentric abrading head during and/or after high-speed rotation of the head. Another embodiment comprises compartments in the abrading head that hold therapeutic agent(s) for release during high-speed rotation. In each case, the therapeutic substance(s) is delivered with radial forces resulting from high-speed orbital rotation of the eccentric abrading head, driving the therapeutic substance(s) into the conduit wall.
US08551125B2
Implantable prostheses for reinforcing and repairing defects in a muscular or tissue wall and a method for fabricating the prostheses that minimizes wasted mesh material and reduces the labor and time required for fabrication. The prosthesis may include a plug body formed of surgical mesh material having a closed end, a larger open end, and a cavity extending therebetween, and a filler body formed of the surgical mesh material comprising a plurality of petals extending radially outwardly from and spaced laterally about a common base disposed in the plug body with the common base attached to the closed end of the plug body. The plug bodies are cut as circular pieces, and the filler bodies are cut as hour-glass shaped pieces from the same sheet of material so as to leave virtually no wasted mesh material. The filler pieces may be attached to the plug body piece by welding.
US08551124B2
An implantation pin for implantation in a target structure has a pinhead and a shaft. The pinhead comprises a pinhead molding portion comprising a moldable material which can be liquefied by application of mechanical energy such as ultrasonic vibration energy. A channel extends through the pinhead and the shaft, the channel connecting the pinhead molding portion to a discharge opening located at the shaft. The moldable material can be liquefied by applying mechanical energy e.g. in the form of ultrasonic vibrations via e.g. a fixation device including an ultrasonic sonotrode and a vibrating tip. The pressure applied by the vibrating tip can be transmitted via the border of the pinhead to the target structure while the liquefied moldable material can be forced through the channel and the discharge opening into a gap between the implantation pin and a recess in a target structure thereby fixing the implantation pin in the target structure.
US08551122B2
Needle-stick injuries are associated with considerable risk of morbidity for healthcare workers and patients. The present invention of a handheld surgical suturing device allows for visualization of surgical field and better control of the suture needle with possible one-hand operation The device also provides active safety features that protect the surgeon from needle-stick injury.
US08551121B2
A bi-directional suture passing instrument is disclosed. The suture passing instrument may include a housing having a first cannulation and a second cannulation that is spaced from the first cannulation by a tissue receiving gap. The instrument may also include a shuttling element movable across the tissue receiving gap between the first and second cannulations. The shuttling element is configured to carry a strand of suture. A first pusher disposed in the first cannulation is configured to push the shuttling element from the first cannulation toward the second cannulation, and a second pusher disposed in the second cannulation is configured to push the shuttling element from the second cannulation toward the first cannulation.
US08551120B2
A combination tissue apposition and suture capturing device (100) for performing endoscopic procedures typically in the gastro-esophageal tract. The device (100) is particularly adapted for forming multiple plications used in a gastroplasty procedure devised to cure or ameliorate gastro-esophageal reflux disease. The device include a tissue sewing capsule (102) attached to the distal end of an endoscope having a needle (120) that is deposited in a capsule (102) distal tip cavity following the suturing of a tissue fold and retrieved to enable the suturing of a subsequent tissue fold without the need for multiple intubations. A suture clip delivery device (200) is also disclosed that is adapted to fit within the capsule to enable suture capture without the need for multiple intubations. The combination device eliminates the need for an overtube and maximizes the speed efficiency of the gastroplasty procedure. A method for using the combination device is also disclosed.
US08551117B2
A skin removal device includes a housing having a handle portion, a drum assembly coupled to the handle portion and including a drum, the drum having an abrasive outer surface configured to abrade skin of a user during rotation of the drum, and an electromechanical drive system disposed at least partially within the housing and configured to rotate the drum. The drum assembly is moveable in a lateral direction relative to the handle portion to enable insertion and removal of the drum assembly.
US08551112B2
An atherectomy device has cannula systems having lumens adapted for insertion of a blood filter and an atherectomy catheter useful for performing atherectomy directly on a patient's cardiovascular tissue. Other embodiments include a lumen for arterial perfusion useful in providing oxygenated blood to the aorta during cardiopulmonary bypass. The distal end of the atherectomy catheter includes an assembly that has a pincer, a loop with or without a mesh, laser, hydraulics, or other suitable mechanism adapted for removing atheroma from a cardiac or vascular tissue. Methods of using the systems for vascular atherectomy are also disclosed herein.
US08551099B2
Disclosed herein are methods, compositions and tools for repairing articular surfaces repair materials and for repairing an articular surface. The articular surface repairs are customizable or highly selectable by patient and geared toward providing optimal fit and function. The surgical tools are designed to be customizable or highly selectable by patient to increase the speed, accuracy and simplicity of performing total or partial arthroplasty.
US08551089B2
A tissue welding apparatus is adapted to fuse a first piece of tissue to a second piece of tissue which are disposed in a surface proximate relationship. An elongate shaft carries a first jaw, and a second opposing jaw moveable relative to the first jaw. At least one penetrating member is carried by the first jaw and moveable relative to the second jaw to create a channel through the first piece of material and the second piece of material. A source of heat is coupled to the penetrating member for denaturing the tissue defining the channel. This denatured tissue forms a column binding the first piece of tissue to the second piece of tissue. A chemical agent can be carried to the tissue with the penetrating member.
US08551084B2
A system that interfaces with a workstation endocardial mapping system allows for the rapid and successful ablation of cardiac tissue. The system allows a physician to see a representation of the physical location of a catheter in a representation of an anatomic model of the patient's heart. The workstation is the primary interface with the physician. A servo catheter having pull wires and pull rings for guidance and a servo catheter control system are interfaced with the workstation. Servo catheter control software may run on the workstation. The servo catheter is coupled to an RF generator. The physician locates a site for ablation therapy and confirms the location of the catheter. Once the catheter is located at the desired ablation site, the physician activates the RF generator to deliver the therapy.