US07709728B2
The highly mismatched alloy Zn1-yMnyOxTe1-x, 0≦y<1 and 0
US07709723B2
Audio samples corresponding to audio extracts or whole audio titles are automatically mapped to triggers 12 in a playable sound-producing device 1, the mapping being dependent on the meta-data associated with the audio samples. Thus, a user can play the sound-producing device and generate sounds derived from his favorite audio titles. It is possible to define different mappings between the audio samples and the playable domain of the sound-producing device: an audio sample selector 50 can select between different possible samples for playback by comparing the audio properties of the samples and the play-mode and/or characteristics of the user's performance. An audio sampler/sample-processor 70 can automatically extract segments of an audio source file and map them to triggers in the sound-producing device 1.
US07709720B1
Described are techniques for preventing movement of tuning pegs on a stringed instrument. Described is a device comprising an elongated body forming a sleeve opened at a first end thereof and having a slit formed therein. The body has a shape and dimensions in accordance with a shape and dimensions of a row of a plurality of tuning pegs of the stringed instrument so that the body is configured to enclose therein head portions of the plurality of tuning pegs. The slit is configured to have a length and width to extend around neck portions of the plurality of tuning pegs on the stringed instrument.
US07709716B1
A foldable music pedal has a stand, a base assembly and a pedal. The stand has a cross bar, a seat and a moving element. The cross bar is defined opposite to the seat. The seat has an inserting recess. The moving element is retractably mounted through the cross bar. The base assembly has a casing base and an inserting base. The casing base is connected pivotally to the seat. The inserting base is movably inserted through the casing base and inserted into the inserting recess of the seat of the stand, and has a connecting end and a bolt. The connecting end of the inserting base extends out of the casing base opposite to the stand. The bolt detachably connects to the casing base and the inserting base. The pedal has two ends respectively connected pivotally to the connecting end of the inserting base and the moving element.
US07709713B1
A vibrato mounting bracket for a guitar, said vibrato unit having a frame having: a) a generally fiat central portion extending from a bottom peripheral edge portion of the guitar, said flat central portion having four vibrato, unit attachment openings therethrough; b) a bottom portion extending from the central portion over the bottom peripheral edge portion of the guitar and having a lower strap screw attachment opening therethrough; and, c) an upper portion extending above the central portion having two opposite lateral openings therethrough spaced to align with i) the two outer string stop bar screws on the guitar, or ii) the two outer bridge attachment screws on the guitar where said guitar has a bridge attachment screw, or iii) the bridge height adjustment screws. The front face and the sound box are then better able to vibrate thereby producing maximum resonance and depth of sound.
US07709708B2
According to the invention, there is provided seed and plants of the hybrid corn variety designated CH323945. The invention thus relates to the plants, seeds and tissue cultures of the variety CH323945, and to methods for producing a corn plant produced by crossing a corn plant of variety CH323945 with itself or with another corn plant, such as a plant of another variety. The invention further relates to genetic complements of plants of variety CH323945.
US07709703B2
The invention relates to the soybean variety designated D5233241. Provided by the invention are the seeds, plants and derivatives of the soybean variety D5233241. Also provided by the invention are tissue cultures of the soybean variety D5233241 and the plants regenerated therefrom. Still further provided by the invention are methods for producing soybean plants by crossing the soybean variety D5233241 with itself or another soybean variety and plants produced by such methods.
US07709695B1
A transgenic non-human animal expressing at least one transgene including a DNA sequence encoding a heterologous Amyloid Precursor Protein (APP) including at least the Arctic mutation (E693G) and a further AD (Alzheimer's disease) pathogenic mutation or a further transgene affecting AD pathogenesis, which results in increased amounts of intracellular soluble A aggregates, including A peptides. The method of producing the transgenic animal, and methods of screening for therapeutic or diagnostic agents useful in treatment or diagnosis of Alzheimer's disease are also disclosed.
US07709684B2
A process for preparing substituted biphenyls of the formula I in which the substituents are defined as follows: X is fluorine or chlorine; R1 is nitro, amino or NHR3; R2 is cyano, nitro, halogen, C1-C6-alkyl, C1-C6-alkenyl, C1-C6-alkynyl, C1-C6-alkoxy, C1-C6-haloalkyl, C1-C6-alkylcarbonyl or phenyl; R3 is C1-C4-alkyl, C1-C4-alkenyl or C1-C4-alkynyl; n is 1, 2 or 3, where in case that n is 2 or 3, the R2 radicals may also be different, which comprises reacting the compound of the formula II in which Hal is halogen and X and R1 are as defined above, in the presence of a base and of a palladium catalyst selected from the group of: a) palladium-triarylphosphine or -trialkylphosphine complex with palladium in the zero oxidation state, b) salt of palladium in the presence of triarylphospine or trialkylphosphine as a complex ligand or c) metallic palladium, optionally applied to support, in the presence of triarylphosphine or trialkylphosphine, in a solvent, with a diphenylborinic acid (III) in which R2 and n are as defined above, where the triarylphosphines or trialkylphosphines used may be substituted.
US07709680B2
The invention provides a process for isocyanate dimerization (uretdione formation) and a process for preparing polyisocyanates having a high content of uretdione groups, using specific phosphines as catalysts. The phosphines have one or two tertiary alkyl radicals bound directly to phosphorus.
US07709679B2
The invention provides a process for the simultaneous preparation of 4,4′-diphenylmethanediamine and also diphenylmethane diisocyanate and polyphenylenepolymethylene polyisocyanates, which comprises the steps a) preparation of a mixture of diphenylmethanediamine and polyphenylenepolymethylenepolyamines by acid condensation of aniline and formaldehyde and subsequent work-up of the mixture, b) splitting-off of part of the mixture prepared in step a), c) distillation of the mixture separated off in step b) in a column, d) recirculation of the bottom product from step c) to the end product from step a) and condensation of the overhead product from step c), e) distillation of the overhead product from step c) in a column, f) recirculation of the overhead product from step e) to the end product from step a), g) isolation of the 4,4′-diphenylmethanediamine obtained as bottom product in step e), h) reaction of the mixture from step a) with phosgene and subsequent work-up of the reaction product.
US07709657B2
The present invention provides an efficient, safe and cost effective way to prepare 5-(4-methyl-1H-imidazol-1-yl)-3-(trifluoromethyl)-benzenamine which is an intermediate for the preparation of substituted pyrimidinylaminobenzamides of formula (II):
US07709653B2
Asymmetric cyanine compounds represented by general formula I are provided, wherein X, n, R1, R2, R3, R4 and Y− are as defined in the specification. They have a maximum absorption peak at about 640 nm which may not change with ambient temperature. When the compounds bind a nucleic acid to form a dye/nucleic acid complex, the fluorescence intensity of the complexes will increased rapidly, so that they can be used as a staining agent for nucleic acids in flow cytometers. Their spectra are in the near-infrared region, which can effectively reduce the interference from background fluorescence and improve the accuracy of detection. Moreover, the compounds provided can also be used as a staining agent for blood reticulocytes.
US07709651B2
A process for producing an optically active cyclopropane compound represented by the formula (4): wherein R3, R4, R5 and R6 are the same or different, and represent a hydrogen atom, a halogen atom, a substituted or unsubstituted alkyl group, and so on; and R7 represents a C1-6 alkyl group; and * represents an asymmetric carbon atom, which comprises reacting a prochiral olefin represented by the formula (2): wherein R3, R4, R5, and R6 are as described above, with a diazoacetic acid ester represented by the formula (3): N2CHCO2R7 (3) wherein R7 is as defined above, in the presence of an asymmetric copper complex prepared from an optically active cycloalkylidenebisoxazoline compound represented by the formula (1): wherein R1 represents a hydrogen atom, a C1-6 alkyl group, and so on; R2 represents a C1-6 alkyl group and so on; and n represents an integer of 0 to 3; provided that, two R1s may be bonded each other together with the carbon atom to which they are bonded to form a ring; and * represents an asymmetric carbon atom, and a copper compound, is provided.
US07709648B2
2-Substituted-5-(1-alkylthio)alkylpyridines are produced efficiently and in high yield.
US07709647B2
The present application describes compounds according to Formula I, pharmaceutical compositions comprising at least one compound according to Formula I and optionally one or more additional therapeutic agents and methods of treatment using the compounds according to Formula I both alone and in combination with one or more additional therapeutic agents. The compounds have the general Formula I: including all prodrugs, pharmaceutically acceptable salts and stereoisomers, R1, R2, R3, n, and Z are described herein.
US07709630B2
Antisense compounds, compositions and methods are provided for modulating the expression of connective tissue growth factor. The compositions comprise antisense compounds, particularly antisense oligonucleotides, targeted to nucleic acids encoding connective tissue growth factor. Methods of using these compounds for modulation of connective tissue growth factor expression and for treatment of diseases associated with expression of connective tissue growth factor are provided.
US07709625B2
The present invention provides an isolated nucleic acid comprising a promoter operably linked to a nucleic acid encoding a peptide or protein and/or an RNA (e.g., antisense or ribozyme), wherein the promoter comprises elements that can include, but are not limited to, a) a myeloid specific promoter element comprising a core sequence GAGGAA; b) a myeloid specific promoter element comprising a core sequence AAGGAGAAG; c) a myeloid specific promoter element comprising a core sequence TTTCCAAA; d) a myeloid specific promoter element comprising a core sequence TGTGGTTGC; e) a myeloid specific promoter element comprising a core sequence TGAGTCA; f) a myeloid associated promoter element comprising a core sequence CCGCCC; and g) any combination of (a), (b), (c), (d), (e) and/or (f), any combination of multiples of (a), (b), (c), (d), (e) and/or (f), in any order and/or in any orientation (forward or reverse).
US07709621B2
The present invention provides cell fusogenic vectors having replicative ability, whose protease-dependent tropism has been modified. M gene-deficient viral vectors encoding modified F proteins, in which the cleavage site of the F protein of paramyxovirus is modified to be cleaved by different proteases, were produced. In cells transfected with these vectors, the genomic RNA present in the vectors is replicated, and cell fusogenic infection spreads to neighboring cells depending on the presence of other proteases; however, no viral particles are released. The vectors of this invention, encoding the F proteins which are cleaved by proteases whose activity is enhanced in cancer, show cancer growth suppressive effect in vivo.
US07709616B2
Described herein are polynucleotides associated with prostate and lung cancer. The polynucleotides are miRNAs and miRNA precursors. Related methods and compositions that can be used for diagnosis, prognosis, and treatment of those medical conditions are disclosed. Also described herein are methods that can be used to identify modulators of prostate and lung cancer.
US07709610B2
The present invention is directed to antagonists of CS1 that bind to and neutralize at least one biological activity of CS1. The invention also includes a pharmaceutical composition comprising such antibodies or antigen-binding fragments thereof. The present invention also provides for a method of preventing or treating disease states, including autoimmune disorders and cancer, in a subject in need thereof, comprising administering into said subject an effective amount of such antagonists.
US07709583B2
A sulfur-containing cyclic olefin resin comprising a unit represented by the following general formula (1) and having a weight average molecular weight of from 1,000 to 1,000,000. (Here, R1 to R6 each independently represents a hydrogen atom, an alkyl group having from 1 to 20 carbon atoms, an aralkyl group having from 1 to 20 carbon atoms, an aromatic group having from 1 to 20 carbon atoms, a cyano group, an alkoxy group having from 1 to 10 carbon atoms or a heterocyclic compound, further R3 to R6 may be a halogen atom, R3 and R4, and R5 and R6 may form a ring containing carbon, oxygen, sulfur or nitrogen, R7 and R8′ each independently represents a hydrogen atom or a methyl group, . . . represents a single bond or a double bond, and l and m each is 0 or 1.)
US07709576B2
A process for preparing a sulfonate terminated polyarylate comprises blending a polyarylate resin with an organic compound to form a reaction mixture, wherein the organic compound contains at least one aliphatic primary amine functional group and at least one other functional group selected from the group consisting of sulfonic acids, sulfonic acid salts, and mixtures thereof, and heating the reaction mixture to a temperature of 225 to 400° C. The temperature of heating is above the glass transition temperature of the polyarylate resin. Sulfonate terminated polyarylates and compositions prepared using the above process, and articles comprising the sulfonate terminated polyarylate compositions, are also disclosed.
US07709558B2
A device and a method for making a tire puncture sealant having a higher concentration of propylene glycol are disclosed, wherein the device comprises: a container having a cylindrical space for a mixed solution of rubber latex and a tackifier; a squirter comprising at least one spout for pouring propylene glycol on the surface of the mixed solution in the container at a rate of 0.01 to 1.0 liter/minute per spout; and an agitator for the mixed solution in the container, comprising a stirring blade rotatable in the mixed solution to cause said surface a current speed of the mixed solution in a range between about 1.0 and about 10.0 meter/second during pouring the propylene glycol.
US07709556B2
Absorbable radiation or radiochemically sterilized medical devices, including sutures, whose breaking strength and absorption profile can be modulated by controlling the total dose received during sterilization are disclosed.
US07709555B2
Coating composition comprising one or more polythiols and one or more polyisocyanates and a latent base catalyst which is activatable by moisture, wherein the equivalence ratio NCO:SH is between 1:2 and 2:1. The latent catalyst is selected from the group of oxazolidine, aldimine, ketimine, and enamine. The latent catalyst is present in an amount of up to 20% relative to the weight of the curable material. The composition further comprises one or more photoinitiators in an amount of up to 4% relative to the weight of the curable material.
US07709545B2
Benzophenone/thioxanthone derivatives useful as photoinitiators are provided as well as photopolymerizable compositions comprising the benzophenone/thioxanthone derivatives.
US07709540B2
The present invention belongs to a method for preparing organic ligand-capped titanium dioxide nanocrystals, wherein the method comprises steps of using methyl titanate, ethyl titanate, n-propyl titanate, iso-propyl titanate, butyl titanate or titanium tetrachloride as a titanium source, and with capping by oleic acid or an organic capping agent, reacting the titanium source in an organic non-polar solvent with an aqueous alkaline substance solution in the interface at a temperature of 25 to 280° C. for 0.5 to 240 hrs, thus a transparent sol containing titanium dioxide nanocrystals is obtained, said the titanium dioxide nanocrystals have particle diameters of 1-20 nm. The preparing process has the features of mild reaction conditions and is a simpler and easier method with a shorter preparation period, thereby facilitating the industrialization.
US07709536B2
The invention relates to pharmaceutical formulations, and more particularly to formulations containing cannabinoids for administration via a pump action spray. In particular, the invention relates to pharmaceutical formulations, for use in administration of lipophilic medicaments via mucosal surfaces, comprising: at least one lipophilic medicament, a solvent and a co-solvent, wherein the total amount of solvent and co-solvent present in the formulation is greater than 55% wt/wt of the formulation and the formulation is absent of a self emulsifying agent and/or a fluorinated propellant.
US07709535B2
The present invention relates to compounds capable of acting as androgen receptor antagonists, pharmaceutical formulations containing the same, and methods of use thereof. Such uses include, but are not limited to, use as antitumor agents, particularly for the treatment of cancers such as colon, skin and prostate cancer and to induce androgen receptor antagonist activity in a subject afflicted with an androgen-related affliction. Examples of androgen-related afflictions include, but are not limited to, baldness, hirsutism, behavioral disorders, acne, and uninhibited spermatogenesis wherein inhibition of spermatogenesis is so desired.
US07709533B2
The present invention provides a class of chemical compounds useful in the treatment of sickle cell disease, diseases characterized by unwanted or abnormal cell proliferation and for the treatment of ocular disorders such as glaucoma. The active compounds are tri-(aryl or heteroaryl) methane compounds or analogues thereof which further comprise an imine moiety and where the tertiary carbon atom can be replaced with a different atom such as Si, Ge, N or P. The compounds enhance resistance to degradation in a biological medium, inhibit potassium flux in a cell, reduce mammalian cell proliferation, reduce the Gardos channel of erythrocytes, reduce sickle erythrocyte dehydration and/or delay the occurrence of erythrocyte sickling or deformation.
US07709528B2
Novel compounds of the general formula (I), the use of these compounds as pharmaceutical compositions, pharmaceutical compositions comprising the compounds and methods of treatment employing these compounds and compositions. The present compounds may be useful in the treatment and/or prevention of conditions mediated by Peroxisome Proliferator-Activated Receptors (PPAR), in particular the PPARδ suptype.
US07709524B2
Use of tellurium-containing compounds for treating conditions in which inhibition of caspase-1/interleukin-1β enzyme (ICE) is beneficial is disclosed.
US07709519B2
Compounds useful as GnRH receptor antagonists are provided. The present inventors have further examined propane-1,3-dione derivatives and confirmed as a result that a propane-1,3-dione having 2-(1,3-dihydro-2H-benzimidazol-2-ylidene), or a compound which has benzene or thiophene ring substituted with a group derived from 1-hydroxymethyl, shows excellent availability, in addition to its excellent GnRH receptor antagonism, thereby accomplishing the invention. Since the compound of the invention shows excellent availability, in addition to its strong GnRH receptor antagonism, it can be expected that it exerts superior drug effect in the living body, and it is useful for the treatment of sex hormone dependent diseases such as prostate cancer, breast cancer, endometriosis, uterine leiomyoma, benign prostatic hypertrophy and the like. In addition, since the compound of the invention is excellent in metabolic stability in human and also is less in drug interaction, it has more desirable properties as a medicament to be used for the aforementioned diseases.
US07709513B2
The invention relates to benzooxazol-2-one derivatives of general formula (I) with the meanings indicated in the description, the pharmaceutically usable salts thereof, and the use thereof as medicinal substances.
US07709511B2
The present invention provides compounds of formula (I) wherein e, R1, R2, R3, R4, R5, R4, R5, R6, R7, R7a, R7b, A, D, m and n are as defined in the specification, processes for their preparation, pharmaceutical compositions containing them and their use in therapy.
US07709506B2
Compounds of formula (I): are inhibitors of p38 kinase and are useful in the treatment of conditions or disease states mediated by p38 kinase activity or mediated by cytokines produced by the activity of p38.
US07709500B2
The invention provides compounds of formula (I): wherein: X is CH2, O, S(O)2 or NR10; Y is a bond, CH2, NR35, CH2NH, CH2NHC(O), CH(OH), CH(NHCOR33), CH(NHSO2R34), CH2O or CH2S; Z is C(O), or when Y is a bond Z can also be S(O)2; R1 is optionally substituted aryl, optionally substituted heterocyclyl or C4-6 cycloalkyl fused to a benzene ring; and R2, R3, R4, R5, R6, R7 and R8, R9, R10, R32, R33, R34 and R35 are as defined herein; are modulators of chemokine (especially CCR3) activity (for use in, for example, treating asthma). The invention also provides a process for making 4-(3,4-dichlorophenoxy)piperidine, which is useful as an intermediate for making certain compounds of the invention.
US07709497B2
The invention provides 4-{[1-(aminocarbonyl)-4-piperidinyl]amino}-N-[(3,4-dimethylphenyl)methyl]-1-ethyl-1H-pyrazolo[3,4-b]pyridine-5-carboxamide, which is the compound of formula (I): or a salt thereof.
US07709492B2
Compounds having the structural formula I or a pharmaceutically acceptable salt thereof, wherein R is optionally substituted phenyl, furanyl, thienyl, pyridyl, pyridyl N-oxide, oxazolyl or pyrrolyl, or cycloalkenyl R1, R2, R3, R4 and R5 are H, alkyl or alkoxyalkyl; and Z is optionally substituted aryl or heteroaryl are disclosed. Also disclosed is the use of compounds of formula I in the treatment of central nervous system diseases, in particular Parkinson's disease, alone or in combination with other agents for treating Parkinson's disease, and pharmaceutical compositions comprising them.
US07709485B2
This invention relates to novel compounds of Formula (I) to (VII), and compositions thereof, useful in the treatment of disease states mediated by the chemokine, Interleukin-8 (IL-8).
US07709481B2
The inventive compounds of the present invention are comprised of phenyl and pyridinyl-1,2,4-oxadiazolone derivatives and their physiologically acceptable salts and functional derivatives that are shown to provide peroxisome proliferator activator receptor (PPARdelta) agonist activity. The compounds of the present invention are comprised of the formula: wherein the substituents R1-R5 and R7-R10 are defined herein. The compounds are therapeutically effective in the regulation and modulation of lipid and carbohydrate metabolism in mammals and are thus suitable for the treatment of diseases such as type-2 diabetes, atherosclerosis, cardiovascular disorders and the like.
US07709478B2
The present invention relates to compounds according to the general formula (I), wherein R1-R4 have the meanings given in the description, A is CH2, CHOH or CH—(C1-C3-alkyl), B, C and D are independently CH2 or CH—(C1-C3-alkyl), and R5 is an aryl or heteroaryl group, possibly substituted by the substituents listed in the description. These compounds are useful for the manufacture of medicaments for the treatment of cardiovascular diseases, stable or unstable angina pectoris, coronary heart disease, Prinzmetal angina, acute coronary syndrome, heart failure, myocardial infarction, stroke, thrombosis, peripheral artery occlusive disease, endothelial dysfunction, atherosclerosis, restenosis, endothelial damage after PTCA, hypertension, essential hypertension, pulmonary hypertension, secondary hypertension, renovascular hypertension, chronic glomerulonephritis, erectile dysfunction, ventricular arrhythmia, diabetes, diabetes complications, nephropathy, retinopathy, angiogenesis, asthma bronchiale, chronic renal failure, cirrhosis of the liver, osteoporosis, or restricted memory performance or for a restricted ability to learn, or the lowering of cardiovascular risk of postmenopausal women or after intake of contraceptives.
US07709475B2
The present invention relates to a compound represented by Formula [I]: wherein X is O, S, NH or CH2; Y1, Y2, Y3, Y4 and Y5, which may be identical or different, are each CH or N; however, at least one of Y1, Y2, Y3, Y4 and Y5 is N; Z1 and Z2, which may be identical or different, are each CH or N; n is an integer from 1 to 3; R1 is a C3-C8 cycloalkyl group, a C6-C10 aryl group, an aliphatic heterocyclic ring or an aromatic heterocyclic ring, or a bicyclic aliphatic saturated hydrocarbon group; R2 and R3, which may be identical or different, are each a hydrogen atom, a lower alkyl group, a lower alkenyl group, a C3-C8 cycloalkyl group, a C6-C10 aryl group, an aromatic heterocyclic ring, or the like; and R4 is a hydrogen atom, a lower alkyl group, a C3-C6 cycloalkyl group or the like, or a pharmaceutically acceptable salt or ester thereof, and a selective inhibitor against Cdk4 and/or Cdk6 or an anticancer agent containing the compound or a pharmaceutically acceptable salt or ester thereof.
US07709471B2
There is provided a compound of formula (I): processes for the manufacture thereof, pharmaceutical compositions thereof and uses in therapy.
US07709466B2
The present invention relates to pyridazinone compounds and their derivatives according to the general formula (I), with the substituents X, R1 and R2 defined herein, as well as their physiologically acceptable salts, methods for producing these compounds and their use as pharmaceuticals. These compounds are kinase inhibitors, in particular inhibitors of the kinase GSK-3β (glycogen synthase kinase-3β) which are useful in the treatment of neurodegenerative diseases such as Alzheimer's disease, Parkinson's disease, strokes, cranial and spinal traumas and peripheral neuropathies, obesity, metabolic diseases, type II diabetes, essential hypertension, atherosclerotic cardiovascular diseases, polycystic ovary syndrome and syndrome X or immunodeficiency.
US07709461B2
The invention relates to methods for delivering polysaccharides by a pulmonary route to achieve local and systemic therapeutic effects. The polysaccharides may be formulated or unformulated and in some instances have an extremely fast absorption rate.
US07709456B2
Synthesis of a target transcript of a gene is selectively increased in a mammalian cell by contacting the cell with a polynucleotide oligomer of 12-28 bases complementary to a region within a target promoter of the gene under conditions whereby the oligomer selectively increases synthesis of the target transcript.
US07709451B2
The present invention provides methods and compositions for treating immune complex associated diseases (ICAD), such as SLE, rheumatoid arthritis, and hepatitis-C related immune complex disease (e.g., cryoglobulinemia) in a subject having an ICAD or at risk for developing ICAD. The invention is based upon the surprising finding that chromatin-containing immune complexes activate autoreactive B cells and dendritic cells by a dual receptor engagement process which, in both cell types, involves a Toll-like receptor (TLR). The methods of treating ICAD comprise administering a compound to an individual in need thereof that either 1) inhibits formation of the immune complex either by preventing formation and/or binding to the TLR, or 2) interferes with binding of an autoantigen-containing immune complex (or the antigenic component thereof) to the TLR, or 3) inhibits signaling pathways initiated by dual engagement of BCR and TLR (in B cells) or FcR and TLR (in dendritic cells) via immune complexed or uncomplexed autoantigens.
US07709440B2
The present invention provides a method of treating a cancer using a neurotoxin, preferably Botulinum toxin (“BTX”). The application of a neurotoxin around a cancer acts to decrease the contractile forces of the muscles surrounding a neoplasm which normally squeeze cancer cells through efferent channels leaving the cancer vicinity to distant sites. Also, the application of the toxin at sites distant from the cancer enhances cellular and humoral immunologic functions which further contributes to cancer cell death and spread. Following administration of botulinum toxin around and distant to a cancer, it is noticed that local, regional, and distant spread is reduced or eliminated. Immunomodulation with botulinum toxin is also valuable in treating other disease that may or may not be associated with cancers, such as viral-induced growths, viral conditions, fungal disease, chronic wounds, graft versus host disease, autoimmune disease, and HIV.
US07709437B2
A process for preparation of co-granules including one or more bleach activators and one or more bleach agent compounds is described. The bleach component is mixed and coated with a binder selected from the group of fatty acids, fatty acid polyol esters, polyglycols and fatty alcohol oxalkylates. One or more bleach activators is added to this mixture followed by granulation or agglomeration in a mixer, resulting in a bleach co-granule composition including the bleach activator and peroxide components.
US07709435B2
There is provided an alkaline cleaning of aluminum alloy, in which the attained corrosion resistance is equal or superior to the acidic cleaning agent, and which mitigates the disadvantages of the acidic cleaning agent, such as corrosion of plant, processing of the waste liquid, and energy cost, and which attains improved productivity.The cleaning liquid from 0.5 to 40 g/L in total of one or more alkali builders selected from alkali metal hydroxide, alkali metal carbonate, inorganic alkali metal phosphate and alkali metal silicate, from 0.2 to 10 g/L of one or more of organic phosphonic acid and its salt (A), from 0.001 to 2 g/L of one or more metallic ions (B) selected from metallic ions having from 5.0 to 14.0 of stability constant with the organic phosphonic acid and its salt, and from 0.1 to 10 g/L of surfactant. Particularly, the weight ratio of (A):(B) is in a range of from 100:0.05˜20.
US07709430B2
A cleansing composition containing the following components (A) to (C): (A) an anionic surfactant (B) a copolymer of a dialkyl diallyl ammonium salt/acrylamide (C) fatty acid alkanolamide and/or polyoxyethylene alkyl ether, wherein pH at 25° C., in 20 weight times water dilution, is 2 to 4.5. The present cleansing composition has a good foamability in hair washing, a fine-textured and soft foam quality, and in particular, a good smoothness in rinsing and lasting the smoothness longer in rinsing.
US07709426B2
The present invention provides a solid stick composition comprising a thermosetting resin and a grease. Optionally, the solid stick composition may comprise a lubricant, a friction modifier, a thermoplastic plasticizer or a combination thereof. The solid stick compositions may be used for application between two metal surfaces in sliding and rolling-sliding contact such as steel wheel-rail systems including mass transit and freight systems. A method of reducing energy consumption, or controlling friction between a metal surface and a second metal surface by applying the solid stick composition to one or more than one of the metal surfaces, is also provided.
US07709425B2
An oxidized olefin wax useful as a pour point depressant for hydrocarbon compositions and/or additive to reduce the wax particle size of wax precipitates in hydrocarbon compositions is described. Method for reducing the pour point and/or wax particle size of hydrocarbon composition with an oxidized olefin wax are described.
US07709417B2
The present invention is directed to providing a security sticker which is hard to be counterfeited, cannot be reused if being released and includes a printed image that is stable over a long period of time, and is directed to providing a method for manufacturing the same. The security sticker of the present invention includes: a surface resin layer (A)1 that has a weak affinity with a sublimable dye and allows the dye to penetrate; a print layer (B)2 that contains a low-molecular-weight compound with a molecular weight of 1300 or less in an amount of 0% to 20 wt % inclusive, has an affinity with the dye, and includes an image formed in a thickness direction of the layer by the dye; a self-destructive film layer (C1)3; and a pressure-sensitive adhesive layer (D1)4 in this order, wherein the self-destructive film layer (C1) includes a dye migration preventive resin layer (E) for preventing migration of the dye and a self-destructive layer (F), and the dye migration preventive resin layer (E) is a resin layer containing a certain kind of a vinyl resin as a main component, or a certain kind of a biaxially stretched film.
US07709415B2
Activated carbon useful as polarizable electrode material for an electric double-layer capacitor can be obtained by mixing a carbonaceous material and an alkali metal hydroxide while maintaining a solid state, granulating the obtained mixture while maintaining its solid state, dehydrating the obtained granulated substance while maintaining its solid state, and subjecting the granulated dehydration product obtained in the dehydration step to an activation treatment. The preferred pressure of the granulation treatment in the granulation step is 0.01 to 300 Torr, and the preferred temperature of the granulation treatment is 90 to 140° C. The preferred pressure of the dehydration treatment in the dehydration step is 0.01 to 10 Torr, and the preferred temperature of the dehydration treatment is 200 to 400° C.
US07709410B2
The invention relates to Group 1 metal/silica gel compositions comprising silica gel and an alkali metal or an alkali metal alloy. The compositions of the inventions are described as Stage 0, I, II, and III materials. These materials differ in their preparation and chemical reactivity. Each successive stage may be prepared directly using the methods described below or from an earlier stage material. Stage 0 materials may, for example, be prepared using liquid alloys of Na and K which are rapidly absorbed by silica gel (porous SiO2) under isothermal conditions, preferably at or just above room temperature, to form loose black powders that retain much of the reducing ability of the parent metals. When the low melting Group 1 metals are absorbed into the silica gel, a mild exothermic reaction produces Stage I material, loose black powders that are indefinitely stable in dry air. Subsequent heating to 400° C. produces Stage II materials, which are also loose black powders. Further heating above 400° C. forms Stage III material with release of some Group 1 metal. It is believed that Stage I, H and III materials represent reductions of the silica gel after absorption of the Group 1 metal. Preferred Group 1 metal/silica gel compositions of the invention are those containing sodium, potassium, or sodium-potassium alloys with sodium and sodium-potassium alloys being most preferred. Each stage of the Group 1 metal/silica gel composition of the invention may be used as a reducing agent reacting with a number of reducible organic materials in the same manner known for alkali metals and their alloys.
US07709408B2
The invention relates to a catalyst consisting of at least: one matrix comprising at least one oxide which is selected from an amorphous oxide, an oxide with low crystallinity and a mixture of both; at least one solid microporous crystalline material which, in the calcined and anhydrous state, has the molar compositions X2O3:nYO2:mZO2, in which X is a trivalent element such as, for example, Al, B, Fe, In, Ga, Cr, Y is at least one trivalent element that is different from Ge and Z is Ge, the value (n+m) is at least equal to 5 and can be between 5 and ∞, and the value of n/m is at least equal to 1; and at least one hydrogenating compound, preferably Pt, Pd, It, Ru, Rh, and Re or a combination of same. The invention also relates to the use of said catalyst in a process in order to improve the quality of diesel fractions.
US07709406B2
Described herein are alkali-free, boroalumino silicate glasses exhibiting desirable physical and chemical properties for use as substrates in flat panel display devices, such as, active matrix liquid crystal displays (AMLCDs). The glass compositions possess numerous properties that are compatible with the downdraw process, particularly fusion drawing.
US07709405B2
A non-woven material including first effect fibers, first binder fibers, second binder fibers, and optionally second effect fibers. The non-woven material has a first planar zone and a second planar zone. The first planar zone includes a greater concentration of first effect fibers and first binder fibers. The second planar zone includes a greater concentration of second effect fibers and second binder fibers. The first planar zone can include a first surface skin associated with the first planar zone on the exterior of the non-woven material, and a second surface skin associated with the second planar zone on the exterior of the non-woven material. The non-woven material has a woven, knitted, or non-woven layer added on either one or both sides of the non-woven material.
US07709402B2
Electronic apparatus and methods of forming the electronic apparatus include a HfSiON film on a substrate for use in a variety of electronic systems. The HfSiON film may be structured as one or more monolayers. The HfSiON film may be formed by atomic layer deposition. Electrodes to a dielectric containing a HfSiON may be structured as one or more monolayers of titanium nitride, tantalum, or combinations of titanium nitride and tantalum. The titanium nitride and the tantalum may be formed by atomic layer deposition.
US07709400B2
Methods for cleaning semiconductor wafers following chemical mechanical polishing are provided. An exemplary method exposes a wafer to a thermal treatment in an oxidizing environment followed by a thermal treatment in a reducing environment. The thermal treatment in the oxidizing environment both removes residues and oxidizes exposed copper surfaces to form a cupric oxide layer. The thermal treatment in the reducing environment then reduces the cupric oxide to elemental copper. This leaves the exposed copper clean and in condition for further processing, such as electroless plating.
US07709398B2
The invention relates to a method and device for depositing at least one layer, particularly a semiconductor layer, onto at least one substrate, which is situated inside a process chamber of a reactor while being supported by a substrate holder. The layer is comprised of at least two material components provided in a fixed stoichiometric ratio, which are each introduced into the reactor in the form of a first and a second reaction gas, and a portion of the decomposition products form the layer, whereby the supply of the first reaction gas, which has a low thermal activation energy, determines the growth rate of the layer, and the second reaction gas, which has a high thermal activation energy, is supplied in excess and is preconditioned, in particular, by an independent supply of energy. The first reaction gas flows in a direction toward the substrate holder through a multitude of openings, which are distributed over a surface of a gas inlet element, said surface being located opposite the substrate holder. According to the invention, the second process gas is preconditioned with a plasma before entering the process chamber, and it enters the process chamber at the edge of the substrate holder directly thereabove and flows parallel to the substrate holder surface.
US07709394B2
A method for processing a substrate having an insulation film and a metal layer thereon comprises the steps of supplying a carboxylic acid anhydride to the substrate, and heating the substrate during the step of supplying the carboxylic acid anhydride to the substrate.
US07709392B2
A method of removing a silicon nitride or a nitride-based bottom etch stop layer in a copper damascene structure by etching the bottom etch stop layer is disclosed, with the method using a high density, high radical concentration plasma containing fluorine and oxygen and further optionally N2 and any one of inert gases, to minimize back sputtering of copper underlying the bottom etch stop layer and surface roughening of the low-k interlayer dielectric caused by the plasma.
US07709383B2
A film forming method comprising forming a liquid coating film on a substrate by supplying a liquid containing a coating type thin film forming substance and a solvent onto the substrate, substantially converging a variation in film thickness of the coating film, making the coating film stand by in an atmosphere including moisture under a predetermined condition after the substantial-convergence, the predetermined condition being such that a product of a time for which the coating film is exposed to the atmosphere and a water content per unit volume in an atmosphere in the vicinity of a surface of the coating film is made to be greater than or equal to a predetermined value, and forming a solid thin film on the substrate after the stand-by, the thin film being formed by carrying out an elimination of the solvent in the coating film and heat treatment for generating an irreversible reaction to the coating type thin film forming substance in the coating film.
US07709379B2
An electrical device having carbonized conductors and a method and a device for the production thereof is disclosed. The electrical device has electrical components having connections. Furthermore, there are situated between the electrical components regions made of plastic with conductors having carbonized plastic and/or agglomerated nanoparticles. The conductors are connected to the connections of the components and/or to external connections of the electronic device.
US07709377B2
A thin film including multi components and a method of forming the thin film are provided, wherein a method according to an embodiment of the present invention, a substrate is loaded into a reaction chamber. A unit material layer is formed on the substrate. The unit material layer may be formed of a mosaic atomic layer composed of two kinds of precursors containing components constituting the thin film. The inside of the reaction chamber is purged, and the MAL is chemically changed. The method of forming the thin film of the present invention requires fewer steps than a conventional method while retaining the advantages of the conventional method, thereby allowing a superior thin film yield in the present invention than previously obtainable.
US07709362B2
A method for introducing impurities includes a step for forming an amorphous layer at a surface of a semiconductor substrate, and a step for forming a shallow impurity-introducing layer at the semiconductor substrate which has been made amorphous, and an apparatus used therefore. Particularly, the step for forming the amorphous layer is a step for irradiating plasma to the surface of the semiconductor substrate, and the step for forming the shallow impurity-introducing layer is a step for introducing impurities into the surface which has been made amorphous.
US07709354B2
A 1×N wavelength selective switch which can function as a dynamic channel equalizer when N=1. In an exemplary arrangement, the present invention is a free-space device that includes a linear array of micromachined reflective elements for beam steering of individual wavelength channels. In at least some embodiments the array of reflective elements of the present invention provides a substantially seamless design such that the optical spectrum appears flat across the transition between actuators. Various embodiments provide high channel bandwidth with flat-top channel performance, low polarization dependence loss, low vibration sensitivity, extinction ratios greater than 40 dB over all temperatures, and very low levels of electrical and optical channel cross-talk.
US07709348B2
The present invention provides a method for manufacturing a semiconductor device, comprising the steps of preparing a substrate having a quartz support substrate and a silicon layer, forming a base or substrate silicon oxide film over the entire upper surface of the silicon layer, forming a silicon nitride film over the entire upper surface of the substrate silicon oxide film by a plasma CVD method, patterning the silicon nitride film thereby to form a mask pattern having a circumferential exposure portion that exposes the substrate silicon oxide film in a circumferential area, a first opening pattern that exposes the substrate silicon oxide film in an element isolation area, and a second opening pattern that exposes the substrate silicon oxide film within a peripheral area, and thermally oxidizing the substrate using the mask pattern as a mask thereby to form an element isolation structure portion in the element isolation area.
US07709344B2
A method comprises depositing a dielectric film layer, a hard mask layer, and a patterned photo resist layer on a substrate. The method further includes selectively etching the dielectric film layer to form sub-lithographic features by reactive ion etch processing and depositing a barrier metal layer and a copper layer. The method further includes etching the barrier metal layer and hard mask layer by gas cluster ion beam (GCIB) processing.
US07709341B2
A single crystal silicon etching method includes providing a single crystal silicon substrate having at least one trench therein. The single crystal silicon substrate is exposed to an anisotropic etchant that undercuts the single crystal silicon. By controlling the length of the etch, single crystal silicon islands or smooth vertical walls in the single crystal silicon may be created.
US07709338B2
A method of fabricating an heterojunction bipolar transistor (HBT) structure in a bipolar complementary metal-oxide-semiconductor (BiCMOS) process selectively thickens an oxide layer overlying a base region in areas that are not covered by a temporary emitter and spacers such that the temporary emitter can be removed and the base-emitter junction can be exposed without also completely removing the oxide overlying the areas of the base region that are not covered by the temporary emitter or spacers. As a result, a photomask is not required to remove the temporary emitter and to expose the base-emitter junction.
US07709325B2
The present invention in one embodiment provides a method of forming an electrode that includes the steps of providing at least one metal stud in a layer of an interlevel dielectric material; forming a pillar of a first dielectric material atop the at least one metal stud; depositing an electrically conductive material atop the layer of the interlevel dielectric material and an exterior surface of the pillar, wherein a portion of the electrically conductive material is in electrical communication with the at least one metal stud; forming a layer of a second dielectric material atop the electrically conductive material and the substrate; and planarizing the layer of the second dielectric material to expose an upper surface of the electrically conductive material.
US07709323B2
Methods of forming a NAND-type nonvolatile memory device include: forming first common drains and first common sources alternatively in an active region which is defined in a semiconductor substrate and extends one direction, forming a first insulating layer covering an entire surface of the semiconductor substrate, patterning the first insulating layer to form seed contact holes which are arranged at regular distance and expose the active region, forming a seed contact structure filling each of the seed contact holes and a semiconductor layer disposed on the first insulating layer and contacting the seed contact structures, patterning the semiconductor layer to form a semiconductor pattern which extends in the one direction and is disposed over the active region, forming second common drains and second common sources disposed alternatively in the semiconductor pattern in the one direction, forming a second insulating layer covering an entire surface of the semiconductor substrate, forming a source line pattern continuously penetrating the second insulating layer, the semiconductor pattern and the first insulating layer, the source line pattern being connected with the first and second common sources, wherein a grain boundary of the semiconductor layer is positioned at a center between the one pair of seed contact structures adjacent to each other, and is positioned over the first common drain or the first common source.
US07709322B2
Methods for fabricating flash memory devices are disclosed. A disclosed method comprises: forming a polysilicon layer on a semiconductor substrate; injecting dopants having stepped implantation energy levels into the polysilicon layer; forming a photoresist pattern on the polysilicon layer; and etching the polysilicon layer to form a floating gate.
US07709319B2
Provided is a semiconductor device including a vertically oriented capacitor extending above the substrate surface and a method of manufacturing such devices in which cell, peripheral and boundary areas between the cell and peripheral areas are defined on a semiconductor substrate. Capacitors are formed in the cell area, a mold pattern is provided in the peripheral areas and an elongated dummy pattern is provided in the boundary areas. The dummy pattern includes a boundary opening in which a thin layer is formed on the elongated inner sidewalls and on the exposed portion of the substrate during formation of the lower electrode. A mold pattern and lower electrode structures having substantially the same height are then formed area so that subsequent insulation interlayer(s) exhibit a generally planar surface, i.e., have no significant step difference between the cell areas and the peripheral areas.
US07709310B2
A semiconductor device has: a semiconductor substrate having a pair of current input/output regions via which current flows; an insulating film formed on the semiconductor substrate and having a gate electrode opening; and a mushroom gate electrode structure formed on the semiconductor substrate via the gate electrode opening, the mushroom gate electrode structure having a stem and a head formed on the stem, the stem having a limited size on the semiconductor substrate along a current direction and having a forward taper shape upwardly and monotonically increasing the size along the current direction, the head having a size expanded stepwise along the current direction, and the stem contacting the semiconductor substrate in the gate electrode opening and riding the insulating film near at a position of at least one of opposite ends of the stem along the current direction.
US07709308B2
Disclosed is a semiconductor device and method of fabricating the same. The device is disposed on a substrate, including a fin constructed with first and second sidewalls, a first gate line formed in the pattern of spacer on the first sidewall of the fin, and a second gate line formed in the pattern of spacer on the second sidewall of the fin. First and second impurity regions are disposed in the fin. The first and second impurity regions are isolated from each other and define a channel region in the fin between the first and second gate lines.
US07709307B2
A nonvolatile memory cell is disclosed, having first and second semiconductor islands at the same horizontal level and spaced a predetermined distance apart, the first semiconductor island providing a control gate and the second semiconductor island providing source and drain terminals; a gate dielectric layer on at least part of the first semiconductor island; a tunneling dielectric layer on at least part of the second semiconductor island; a floating gate on at least part of the gate dielectric layer and the tunneling dielectric layer; and a metal layer in electrical contact with the control gate and the source and drain terminals. In one advantageous embodiment, the nonvolatile memory cell may be manufactured using an “all-printed” process technology.
US07709306B2
A method for forming an electronic device including at least one electrically conductive and one semiconductive material deposited from solution, the method comprising: forming on the substrate a confinement structure consisting of a least a first zone and a second zone, depositing the electrically conductive material on the substrate, wherein the electrically conductive material is absent from both the first and second zone, and subsequently depositing the electrically semiconductive material from solution, wherein the semiconductive material is absent from the first zone, but not from the second zone.
US07709303B2
A process for forming an electronic device can include forming a semiconductor fin of a first height for a fin-type structure and removing a portion of the semiconductor fin such that the semiconductor fin is shortened to a second height. In accordance with specific embodiment a second semiconductor fin can be formed, each of the first and the second semiconductor fins having a different height representing a channel width. In accordance with another specific embodiment a second and a third semiconductor fin can be formed, each of the first, the second and the third semiconductor fins having a different height representing a channel width.
US07709294B2
A method and apparatus for bonding integrated circuits uniquely suited to high volume tag production is described, where conductive material of a substrate at the die-attach-area is cut before an IC chip or transponder is placed on the conductive material over the cut and bonded. The apparatus performs the method of placing a first chip on a substrate having a conductive layer, measuring the location of the first chip on the substrate, cutting the conductive layer at a location of an expected subsequently placed chip to form a cut based on the measured location of the first chip, and placing the subsequently placed chip on the substrate over the cut.
US07709290B2
A method includes chemically bonding a polymeric material to a self-assembled molecular film that is chemically bonded to a surface of a substrate. The self-assembled molecular film includes one or more defect sites and a plurality of active device molecules, each of the plurality of active device molecules including a molecular switching moiety having a self-assembling connecting group at one end of the moiety and a linking group at an opposed end of the moiety. The polymeric material chemically bonds to at least some of the linking groups of the plurality of active device molecules, causing the formation of the self-assembled molecular layer covering the plurality of active device molecules and the defect site(s).
US07709283B2
The invention provides a semiconductor device, a method of manufacturing the same, an electro-optic device and an electronic apparatus which are capable of addressing or solving a problem of mechanical mounting of a semiconductor element chip on a substrate. A semiconductor device includes a tile-shaped microelement bonded to a substrate, and an insulating functional film provided to cover at least a portion of the tile-shaped microelement.
US07709282B2
A production method for producing a light-emitting device 1 in which a light-emitting layer at least comprised of a n-type substrate bearing layer 3 and a p-type substrate bearing layer 4 is layered on a transparent crystal substrate 2 is provided with a step of forming a transfer layer 5 on at least a part of the transparent crystal substrate 2 or the light-emitting layer 3, 4, which transfer layer 5 is softened or set upon supplying an energy thereto; a step of pressing a mold 6 formed with a minute unevenness structure 61 against the transfer layer 5 to transfer the minute unevenness structure 61 to an outer surface of the transfer layer 5, and a step of forming a minute unevenness structure 21, 34 for preventing multiple reflection based on the minute unevenness structure 51 transferred to the transfer layer 5.
US07709278B2
A semiconductor package is disclosed having a single CE signal during electrical test and a plurality of CE signals during normal operation thereafter. After electrical testing of the memory die during fabrication, the electrical traces carrying the single CE signal from the memory test pad matrix to each of the memory die may be severed. Severing the electrical traces from the memory test pad matrix electrically isolates the multiple electrical traces between the controller die and memory die, and allows separate and individual CE signals between the controller die and memory die during normal usage of the memory die.
US07709276B2
A by-product (e.g., RuF5) that is produced in the process of cleaning may cover a cleaning subject film and may obstruct the progress of the cleaning. To suppress an accumulation of the by-product, a cleaning operation is divided into plural operations, performing vacuum evacuation between the divided operations to evaporate the by-product and expose a new surface of the cleaning subject film between each supply of cleaning gas.
US07709267B2
A system and method for extracting headspace vapor is generally disclosed comprising pressurizing a vessel containing headspace vapor with a carrier gas and subsequently venting the sample mixture through an adsorbent trap and out a vent. A flow controller is employed to gradually increase the flow therethrough as the pressure drops as a result of the gradual depletion of headspace vapor in the vessel and, in certain embodiments, the flow controller maintains a constant flow rate. Due to the time saved, in some embodiments, multiple pressurization-venting cycles are implemented to maximize the amount of vapor extracted from the vial. Due to the constant flow rate, in certain embodiments, the pressure decay is monitored and compared to reference values in order to determine whether the sample vessel has a leak or other defect.
US07709265B2
Prior to adding detergent or chelant, the conductivity of water in a washing chamber is measured. The maximum concentration of hard water ions that could correspond to the measured conductivity is determined, i.e., it is assumed that all of the conductivity is from calcium and/or magnesium ions in the water even though other ions may in fact be contributing to the measured conductivity. Enough chelating agent is added to the chamber to sequester this maximum concentration of hard water ions and the conductivity is measured again. Using the two conductivity measurements, the actual concentration of hard water ions is determined. A chelant factor based on the actual concentration of hard water ions is then used to determine the amount of chelant to be added for subsequent wash cycles to sequester all of the hard water ions.
US07709264B2
A method and system for detecting tobacco-specific nitrosamines. The method includes exposing at least one microcantilever beam to a medium, which may contain tobacco-specific nitrosamines, and measuring a deflection of the microcantilever beam, wherein the deflection indicates a presence of tobacco-specific nitrosamines in the medium. The at least one microcantilever beam can include a silicon base layer and a gold-coated receptor layer with a plurality of thiol molecules having a sulfur head and carboxyl-terminated group. The at least one microcantilever beam can include a silicon base layer and a metal or metal oxide coated receptor layer. Alternatively, the microcantilever beam can be formed by co-absorbing tobacco-specific nitrosamines and silane molecules on a silicon microcantilever surface, wherein the template molecules of tobacco-specific nitrosamines physically co-adsorb between the silane molecules. The template molecules of tobacco-specific nitrosamines are then washed away with a solvent to form a silane monolayer having tobacco-specific nitrosamine cavities.
US07709261B2
The present invention describes a novel recombinant NADH recycling system that is used as a process for producing reduced compounds. In a specific embodiment, the reduced compounds include ethanol, succinate, lactate, a vitamin, a pharmaceutical and a biodegraded organic molecule. The NADH recycling system effects metabolic flux of reductive pathways in aerobic and anaerobic environments.
US07709242B2
The present invention describes the production of L-tyrosine by culturing in a medium an Escherichia bacterium which has L-tyrosine-producing ability and which carries a mutant prephenate dehydrogenase which is desensitized to feedback inhibition by L-tyrosine, producing and accumulating L-tyrosine in the medium or in the bacterial cells, and collecting L-tyrosine from the medium or the bacterial cells.
US07709241B2
A method of making sampling tubes containing culture growth media by loading the sample tubes containing culture media into a tray that holds the sample tubes, placing the sample tube trays into a rack with shelving to hold the trays and tubes at a predetermined angle, and sterilizing and cooling the sample tubes in an autoclave or inspissator. The culture growth media solidifies at the predetermined slant angle and the sample tube trays are loaded into the packaging box used for shipment. The trays are subsequently used by the end user for processing microbial growth, including storing and collecting data about microbial samples.
US07709236B2
A process for producing a crude oil having lowered unsaponifiable matter content and/or ester-type sterol content and comprising a highly unsaturated fatty acid as a constituent fatty acid, characterized in that a microorganism capable of producing a fat or oil comprising an unsaturated fatty acid as a constituent fatty acid is cultured in a medium containing a nitrogen source concentration of 2 to 15% within a culture tank equipped with an agitation impeller satisfying the requirement that the ratio of the diameter of agitation impeller (=d) to the inner diameter of the culture tank (=D) is d/D=0.30 to 0.6.
US07709224B2
Vector constructs for expression of two or more functional proteins or polypeptides under operative control of a single promoter and methods of making and using the same are described. The vectors comprise a self-processing cleavage site between each respective protein or polypeptide coding sequence. The vector constructs include the coding sequence for a self-processing cleavage site and may further include an additional proteolytic cleavage sequence which provides a means to remove the self processing peptide sequence from expressed protein(s) or polypeptide(s). The vector constructs find utility in methods for enhanced production of biologically active proteins and polypeptides in vitro and in vivo.
US07709215B2
The present invention provides methods, reagents and kits for diagnosing and/or for the prognosis of non-autoimmune acute joint inflammation by detecting cytokine biomarkers in a sample obtained from an individual thought to be suffering from joint injury. The cytokine biomarkers used with the methods and kits of the present invention are IL-6, MIP-1β, MCP1 and IFNγ.
US07709214B2
The invention provides isolated nucleic acids molecules, designated PD-L2 nucleic acid molecules, which encode novel B7-related molecules which are ligands for PD-1. The invention also provides antisense nucleic acid molecules, recombinant expression vectors containing PD-L2 nucleic acid molecules, host cells into which the expression vectors have been introduced, and nonhuman transgenic animals in which a PD-L2 gene has been introduced or disrupted. The invention further provides isolated PD-L2 polypeptides, fusion proteins, antigenic peptides and anti-PD-L2 antibodies. The invention still further provides methods for promoting or inhibiting the interaction between PD-L2 and PD-1. Diagnostic and treatment methods utilizing compositions of the invention are also provided.
US07709207B2
Methods and products for the attenuation or treatment of pain and the reduction of nociception are described. The methods and products are based on the modulation of CNS intracellular chloride levels. The methods and products may also relate to modulation of the activity and/or expression of a chloride transporter, such as the KCC2 potassium-chloride cotransporter. Also described herein are commercial packages and uses based on such modulation. Related methods for identifying or characterizing a compound for the treatment of pain, the reduction of nociception and the diagnosis and prognostication of pain are also described.
US07709192B2
A nucleic acid ligand “biochip” is disclosed, consisting of a solid support to which one or more specific nucleic acid ligands is attached in a spatially defined manner. Each nucleic acid ligand binds specifically and avidly to a particular target molecule contained within a test mixture, such as a bodily fluid. The target molecules include, but are not limited to, proteins (cellular, viral, bacterial, etc.) hormones, sugars, metabolic byproducts, cofactor, and intermediates, drugs, and toxins. Contacting the test mixture with the biochip leads to the binding of a target molecule to its cognate nucleic acid ligand. The biochip may then be contacted with a reagent(s) that reacts covalently with proteins and not with nucleic acids. Each protein target in the test mixture may then detected by detecting the presence of the reagent at the appropriate address on the biochip.
US07709191B2
A change in viral tropism occurs in many HIV positive individuals over time and may be indicated by a shift in coreceptor use from CCR5 to CXCR4. The shift in coreceptor use to CXCR4 has been shown to correlate with increased disease progression. In patients undergoing HAART, the predominant populations of virus may be shifted back to CCR5-mediated entry soon after the CXCR4-specific strains have emerged. The present invention relates to a diagnostic method to monitor coreceptor use in the treatment and clinical management of human immunodeficiency virus (HIV) infection. The present invention further relates to a diagnostic method applied to HIV-positive individuals undergoing HAART to monitor the suppression of CCR5- or CXCR4-specific strains. The diagnostic methods may be used to assist in selecting antiretroviral therapy and to improve predictions of disease prognosis over time. The methods of the invention include cell-based methods, including cell fusion assays, and molecular-based methods, including heteroduplex tracking assay, to both quantitatively and qualitatively analyze patient-derived HIV for coreceptor usage.
US07709185B2
In a method for imaging a lithographic printing form, subareas of a surface of the lithographic printing form which are covered by amphiphilic molecules, are exposed to electromagnetic radiation. Following the exposure and before printing from the lithographic printing form, the subareas are treated with at least one complex-forming substance, so that a lithographic printing area structured into hydrophilic and hydrophobic regions is obtained.
US07709183B2
A workpiece 70 is set to holding rotating means and then liquid-state photosensitive resin 10 is supplied to a resin applying smoothing unit 150 to mold the workpiece 70 into a uniform thickness while rotating the workpiece 70 and applying the liquid-state photosensitive resin 10 to the outer periphery of the workpiece 70 by the resin applying smoothing unit 150. Moreover, while rotating the workpiece 70, liquid-state photosensitive resin, it is exposed by high-intensity ultraviolet light 30 and thereby, the surface of the photo-cured photosensitive resin is shaped to remove an unnecessary resin layer. Then, laser carving is performed by an infrared laser beam 40 to perform post-treatment.
US07709181B2
Cyanine compounds represented by the general formula (I) which exhibit decomposition behavior suitable for the optical recording material to be used in optical recording layers of optical recording media for high-speed recording: (I) wherein A and B are each an optionally substituted benzene or naphthalene ring; X is O, S, Se, CR3R4, or NY; at least either of R1 and R2 is a group represented by the general formula (II) or (III) and when only either is a group represented thereby, the other is an organic group having 1 to 30 carbon atoms; R3 and R4 are each an organic group having 1 to 30 carbon atoms; Y is hydrogen or an organic group having 1 to 30 carbon atoms; at least either of Y1 and Y2 is a group represented by the general formula (IV) and when only either is a group represented thereby, the other is hydrogen or an organic group having 1 to 30 carbon atoms; Z is hydrogen, halogeno, or cyano; Anm− is an m-valent anion; m is an integer of 1 or 2; and p is a coefficient capable of keeping the electric charge neutral.
US07709177B2
Multilayered resist structures including bilayer and top surface imaging which utilize tuned underlayers functioning as ARCs, planarizing layers, and etch resistant hard masks whose properties such as optical, chemical and physical properties are tailored to give a multilayer resist structure exhibiting high resolution, residue free lithography and methods of preparing these materials.
US07709168B2
A photoconductor that includes, for example, a supporting substrate, a photogenerating layer, and at least one charge transport layer comprised of at least one charge transport component, and wherein the at least one charge transport layer contains at least one phosphonium salt.
US07709163B2
The present invention facilitates a control of a temperature of white color and color tones of respective colors of a color liquid crystal display device. To achieve such an aim, a display device of the present invention includes a display panel which arranges a plurality of color filters which differ in color for each pixel, and at least the color filter of one color is formed of a plurality of filter layers stacked on a transparent substrate.
US07709154B2
Disclosed is an electrolyte of a lithium secondary battery comprising a lithium salt, an organic solvent, and at least one additive compound selected from the group consisting of compounds represented by the following formula (1) and derivatives thereof: where R1 is selected from the group consisting of hydrogen radicals, alkyls, aryls, cycloalkyls, alkenyls, alkynyls, ester radicals, and aliphatic carbonate radicals. The electrolyte improves both swelling inhibition properties at high temperature and capacity characteristics of a lithium secondary battery.
US07709152B2
An organic/inorganic composite separator includes (a) a polyolefin porous substrate having pores; and (b) a porous active layer containing a mixture of inorganic particles and a binder polymer, with which at least one surface of the polyolefin porous substrate is coated, wherein the porous active layer has a peeling force of 5 gf/cm or above, and a thermal shrinkage of the separator after being left alone at 150° C. for 1 hour is 50% or below in a machine direction (MD) or in a transverse direction (TD). This organic/inorganic composite separator solves the problem that inorganic particles in the porous active layer formed on the porous substrate are extracted during an assembly process of an electrochemical device, and also it may prevent an electric short circuit between cathode and anode even when the electrochemical device is overheated.
US07709151B2
As a positive electrode active material, a lithium transition metal complex oxide having a layered rock-salt structure containing lithium (Li) and containing magnesium atoms (Mg) substituted for part of lithium atoms (Li) is used. The lithium transition metal complex oxide is formed by chemical or electrochemical substitution of Mg atoms for part of Li atoms in LiCoO2, LiMnO2, LiFeO2, LiNiO2, or the like. A cell is prepared in which a negative electrode 2 and a positive electrode 1 including the lithium transition metal complex oxide (positive electrode active material) are disposed in a non-aqueous electrolyte 5 including a lithium salt, and part of Li in the lithium transition metal complex oxide is extracted by discharging the cell. Then, the electrolyte including Li is replaced with an electrolyte including Mg, and the cell is discharged, so that Mg atoms are substituted for the part of Li atoms in the lithium transition metal complex oxide.
US07709144B2
Processes for making rigid, binder free agglomerates of powdered metal are disclosed. The agglomerates have a low tap density. Articles that contain binder free agglomerates made from electrochemically active powder are also disclosed.
US07709143B2
A rechargeable battery includes an electrode assembly having a positive electrode, a negative electrode, and a separator positioned between the positive and negative electrodes, a case for housing the electrode assembly, and a spacer positioned between the electrode assembly and the case.
US07709140B2
A separator for an electrochemical cell, comprising (A) a flexible perforate support, and (B) a porous ceramic material which fills the perforations in the support and is suitable for receiving an ion-conducting electrolyte, wherein the porous ceramic material comprises a first porous layer which is characterized by an average pore size and also at least one second porous layer for contacting with an electrode, the second porous layer having an average pore size which is smaller than the average pore size of the first porous layer.
US07709136B2
A battery pack assembly is provided for supplying electrical power to an electronic device, such as an electronic receiver of an animal confinement system. The battery pack assembly is removably insertable within a receptacle of the electronic receiver to electrically connect a battery contained within the battery pack assembly to internal electronics of the electronic receiver.
US07709130B2
A fuel cell include a membrane electrode assembly including an anode, a cathode opposed to the anode, and an electrolyte membrane interposed between the anode and the cathode; a lyophobic porous body in contact with the anode; and an anode passage plate in contact with the lyophobic porous body, the anode passage plate including a gas collection passage and a fuel supplying passage, the gas collection passage collects a gas generated in the anode via the lyophobic porous body, the fuel supplying passage supplies a fuel to the anode via the lyophobic porous body.
US07709128B2
A separating plate for a fuel cell includes first and second plates, each provided with a hydrogen channel, an oxygen channel, and a coolant channel. The first and second plates are attached to one another to form a main plate such that the first and second hydrogen, oxygen, and coolant channels compose main hydrogen, oxygen, and coolant channels, respectively. The main hydrogen and oxygen channels are fluidly isolated from each other. Distal ends of the main channels each communicate with a manifold through a communication passageway configured to supply hydrogen, oxygen, or coolant to a corresponding one of the main channels.
US07709127B2
A composition useful for the fueling and refueling of electrochemical devices is described. The composition comprises an ion-conducting medium such as an electrolyte, and catalyst nanoparticles. Unlike traditional electrodes, such as those typically used in electrolyzers and fuel cells, the inventive composition may be quickly drained from the device and refilled to maintain maximum cell performance. In addition, the electro-catalytic charging composition can be stored as a solid for safe handling; for example in a portable cartridge.
US07709126B2
Disclosed is a micro power cell capable of being applied as an energy source and utilizing a streaming potential phenomenon occurring in accordance with an electrokinetic principle when an electrolyte aqueous solution flows in the microchannels piled up in several layers. The streaming potential cell consists of a PDMS microfluidic-chip fabricated by MEMS process as well as micromachining technology. The microfluidic-chip is formed with multi microchannels radially arranged in parallel with each other around a center of a disk at a regular interval. The disk type multi microchannel can achieve uniform inflow and outflow effects. According to the invention, there is provided a cell device comprising a pile-up chip having a number of disk type microfluidic-chips with the optimal structure of flow-in and flow-out of a fluid, a distributor, a collector, an electrode insertion part, etc.
US07709125B2
A fuel cell system having a cooling fluid flowing therethrough includes a fuel cell stack in heat transfer communication with the cooling fluid and a conduit through which the cooling fluid flows. The conduit includes a first layer of hydrogen-permeable material. Hydrogen within the cooling fluid permeates through the first layer of hydrogen-permeable material to reduce a hydrogen content of the cooling fluid.
US07709122B2
A method for producing a proton conductive electrolyte membrane in which proton conductivity is sufficiently high, methanol permeability is sufficiently low and physical strength is sufficient for reducing the thickness adequately. The production method includes: laminating a dispersion liquid containing inorganic particles and inflammable organic particles on an inflammable support, the inflammable organic particles having an average particle size of 100 to 450 nm; baking the inflammable support on which the dispersion liquid is laminated; and filling a porous membrane formed of the inorganic particles obtained by the baking with an proton conductive organic material.
US07709119B2
In a method for operating a fuel cell including an electrolyte membrane sandwiched by a fuel electrode and an oxidizing agent electrode, the method includes a hydrogen feedback process either before starting operation of the fuel cell or after stopping operation of the fuel cell. The hydrogen feedback process includes the processes of a process for electrically connecting a positive electrode of an external electric power source to the oxidizing agent electrode of the fuel cell, a process for electrically connecting a negative electrode of the external electric power source to the fuel electrode of the fuel cell, a process for oxidizing hydrogen remaining in the oxidizing agent electrode to generate protons, the hydrogen contained in the fuel, and a process for reducing the protons, transferred to the fuel electrode from the oxidizing agent electrode through the electrolyte membrane, into hydrogen.
US07709117B2
An apparatus for supplying mixed fuel includes a water container storing water; a fuel container storing fuel, including at least gaseous fuel, the fuel container being coupled to the water container by a pressure pipe for transferring internal pressure of the fuel container to the water container; and a mixer coupled to the water container through a water supplying pipe and coupled to the fuel container through a fuel supplying pipe, the mixer outputting mixed fuel through a mixed fuel supplying pipe. A water supplying unit includes a water container storing water and connected to a water supplying pipe, the water container having an outlet; and a pressure applying unit coupled to the water container for applying gas pressure to an inside of the water container to discharge water from the water container through the outlet.
US07709112B2
An information recording medium comprises a substrate, a second recording layer, a second light transmitting layer, a first recording layer for recording different information from that to be recorded in the second recording layer, and a first light transmitting layer. The second recording layer is formed with a continuous second microscopic pattern of grooves. The first recording layer is formed with a continuous first microscopic pattern of grooves that is different from the second microscopic pattern. Both sidewalls of raised portions of the first and second microscopic patterns are formed with wobbling so as to be parallel with each other. Auxiliary information and a reference clock is recorded on these sidewalls alternately and continuously.
US07709111B2
An information recording medium comprises a substrate, a second recording layer, a second light transmitting layer, a first recording layer for recording different information from that to be recorded in the second recording layer, and a first light transmitting layer. The second recording layer is formed with a continuous second microscopic pattern of grooves. The first recording layer is formed with a continuous first microscopic pattern of grooves that is different from the second microscopic pattern. Both sidewalls of raised portions of the first and second microscopic patterns are formed with wobbling so as to be parallel with each other. Auxiliary information and a reference clock is recorded on these sidewalls alternately and continuously.
US07709108B2
An information recording medium comprises a substrate, a second recording layer, a second light transmitting layer, a first recording layer for recording different information from that to be recorded in the second recording layer, and a first light transmitting layer. The second recording layer is formed with a continuous second microscopic pattern of grooves. The first recording layer is formed with a continuous first microscopic pattern of grooves that is different from the second microscopic pattern. Both sidewalls of raised portions of the first and second microscopic patterns are formed with wobbling so as to be parallel with each other. Auxiliary information and a reference clock is recorded on these sidewalls alternately and continuously.
US07709105B2
An OLED device comprises a cathode, an anode, and has therebetween a light-emitting layer containing a phosphorescent emitter and a host comprising a first aluminum or gallium complex containing at least one 2-(2-hydroxyphenyl)pyridine ligand and at least one phenoxy ligand, wherein the phenoxy ligand is substituted by an amine or there is further present adjacent to the light-emitting layer on the cathode side a layer containing a second aluminum or gallium complex containing at least one 2-(2-hydroxyphenyl)pyridine ligand and at least one phenoxy ligand.
US07709103B2
The present invention provides a nano particle phosphor with superior luminous characteristic formed using nitride semiconductor material, a method of manufacturing the phosphor with high production yield, and a light emitting device using the phosphor. The phosphor is formed of a columnar crystal having a diameter of at most 3 nm, a light emitting region and a light absorbing region are defined in the columnar crystal, and the light emitting region and the light absorbing region are adjacent to each other along a longitudinal direction of the columnar crystal.
US07709100B2
An organic light emitting device is provided. The device has an anode, a cathode, and an emissive layer disposed between the anode and the cathode. The emissive layer further includes a molecule of Formula I (shown below) wherein an alkyl substituent at position R′5, which is an alkyl substituent, results in high efficiency and operational stability in the organic light emitting device.
US07709087B2
A fabricated microstructure includes a substrate, a primary fiber, and a plurality of base fibers. The primary fiber has a width less than about 5 microns. Each base fiber of the plurality of base fibers has a first end attached to the primary fiber and a second end attached to the substrate. Each base fiber has a width less than the width of the primary fiber.
US07709085B2
A thermosetting resin composition capable of providing a molding, such as a resin sheet, that excels in not only dielectric characteristics but also dimensional stability at high temperature and even after exposure to high temperature thermal history, exhibits little dimensional change by the thermal history, namely, exhibiting low linear expansion coefficient. There are further provided a resin sheet and resin sheet for insulated substrate produced from the thermosetting resin composition. In particular, there is provided a thermosetting resin composition comprising an epoxy resin of 100 to 2000 epoxy equivalent, an epoxy resin hardening agent consisting of a phenolated compound, and a layered silicate, and are further provided a resin sheet comprised of the thermosetting resin composition and a resin sheet for insulated substrate comprised of the resin sheet.
US07709080B2
Disclosed is a display device. The display device includes first and second substrates facing each other, a sealant pattern including a first compound attaching the first and the second substrates together, and a separator pattern within the sealant pattern. The separator pattern includes a second compound chemically reacting with the first compound to block the diffusion of the first compound.
US07709072B2
An adhesive pattern for a label system is disclosed. The adhesive pattern includes a label sheet having a plurality of non-adhesive sections, and a plurality of adhesive sections connected to the non-adhesive sections. The non-adhesive sections and the adhesive sections are in alternate arrangement to form the label sheet. The label sheet also includes a plurality of labels having a first end and a second end, and the first end is attached to a non-adhesive section. Upon removal of the label from a non-adhesive section, the label has a non-sticking surface.
US07709070B2
Articles for applying color on a surface comprise a sheet of dry color component and an adhesive on one surface of the sheet of dry color component. The article further includes a releasable liner, and the sheet of dry color component is arranged between the releasable liner and the adhesive. Methods for providing a substantially permanent color effect on an architectural surface comprise delivering such an article to the architectural surface.
US07709066B2
A liquid crystal composition is provided that satisfies at least one characteristic among the characteristics such as a high maximum temperature of a nematic phase, a low minimum temperature of a nematic phase, a small viscosity, a large optical anisotropy, a large dielectric anisotropy, a large specific resistance, a high stability to ultraviolet light and a high stability to heat, or is properly balanced regarding at least two characteristics. An AM device is provided that has a short response time, a large voltage holding ratio, a large contrast ratio, a long service life and so forth. The liquid crystal composition contains a specific tricyclic compound having a large optical anisotropy as the first component and a specific tetracyclic compound having a large dielectric anisotropy as the second component, and may contain a specific bicyclic compound having a particularly small viscosity as the third component. The liquid crystal composition has a nematic phase. The liquid crystal display device contains the liquid crystal composition.
US07709062B2
A hole in a sample from which a sample piece has been extracted with a focused ion beam is filled at high speed using ion beam gas assisted deposition. A method of filling the hole by using the ion beam includes a step of irradiating the hole formed in a face of the sample with the ion beam to thereby form an ion beam gas-assisted deposition layer in the hole. The ion beam gas-assisted deposition layer is formed in the hole while controlling the area to which the ion beam is irradiated so as to cause the ion beam to fall on a part of a side wall of the hole and to not fall on another part of the side wall in an area scanned with the ion beam. The filled hole may then be covered with a protective film.
US07709058B2
A process for coating metals, selected from aluminum and its alloys, zinc and its alloys, and galvanized or alloy-galvanized steel, in which the metal is given a weather-resistant protective coating, wherein the metal is cleaned if necessary, and thereafter subjected to a conversion treatment; optionally flushed with water and/or dried; brought into contact with a coating agent which comprises aliphatic cross-linking urethane resins, cross-linking agents, anti-corrosion pigments, one or more organic solvents and/or water and, if desired, other active or auxiliary substances; and then cured.
US07709053B2
A method of manufacturing polymer-coated particles is useful for chemical mechanical polishing magnetic, optical, semiconductor or silicon substrates. First it provides a dispersion of particle cores in a non-aqueous solvent. Then introducing a polymeric precursor into the dispersion to react the polymeric precursor forms a polymer. The polymer coats at least a portion of the surface of the particle cores with the polymer and forms the polymer-coated particles having a solid outer polymeric shell. Substituting the non-aqueous solvent with water forms an aqueous mixture containing the polymer-coated particles. And it forms an aqueous chemical mechanical polishing formulation with the polymer-coated particles without drying the polymer-coated particles.
US07709052B2
Alkyldiketene-containing aqueous polymer dispersions which are obtainable by miniemulsion polymerization of hydrophobic monoethylenically unsaturated monomers in the presence of alkyldiketenes, processes for the preparation of such polymer dispersions and the use of the thus obtainable dispersions as sizes for paper or as water repellents for leather, natural and/or manmade fibers and textiles.
US07709040B2
A process for treating tomato concentrates obtainable by concentration by evaporation, having a dry residue in percentage by weight higher than 15%, generally at least of about 18%, comprising the following steps: I) mixing of the tomato concentrate (component a)) with water (component b)); II) liquid separation by a separation solid-liquid apparatus, wherein the mass to be filtered is maintained under a slow stirring; III) addition of water and/or serum to the solid mass obtained in II).
US07709036B2
A method for producing granules made from malt extract is provided. The method provides for producing granules continuously or in batches under the prevention as much as possible of non-uniform temperature distributions in the production process. Simultaneously, the controllability of the granulation in the production is improved. This is realized by linking thermal conditions in the spraying zone and the temperature conditions in other region of the apparatus. This is achieved such that the supply of the heated process gas for drying is realized exclusively in the spraying region. The reliable supply of particles into the spraying region is performed through the special geometric configuration of the apparatus under the use of gravity.
US07709030B2
A description follows of mixtures of copper (II) hydroxide with at least one other cupric salt having the formula (A) and their use for the control of phytopathogenic fungi.
US07709027B2
The invention relates to an anti-inflammatory, wound-healing glass powder, whereby the glass of the glass powder comprises the following components: 20-80 wt. % SiO2, 0-40 wt. % Na2O, 0-40 wt. % K2O, 0-40 wt. % Li2O, 0-40 wt. % CaO, 0-40 wt. % MgO, 0-40 wt. % Al2O3, 0-1 wt. % P2O5, 0-40 wt. % B2O3 and 0-10 wt. % ZnO.
US07709026B2
The invention relates to a pharmaceutical vaginal composition for treating or preventing vaginal infections. The composition includes a synergistic mix of a bioadhesive, extended release formulation that decreases the pH and that contains a peroxide in an amount sufficient to increase oxygen concentration without sterilizing the vagina or substantially killing the normally-desired local vaginal flora. The invention also relates to a method of treating or preventing vaginal infections in a patient comprising inserting vaginally an amount of the pharmaceutical vaginal composition in an amount sufficient to decrease the pH and increase oxygen concentration without sterilizing the vagina or substantially killing the normally-desired local vaginal flora.
US07709025B2
Enteric film coating systems for orally ingestible substrates such as pharmaceutical tablets and dietary supplements are disclosed. In preferred aspects, the enteric film coatings include an ethylcellulose dispersion and a substantially gastro-insoluble pore former such as sodium alginate.
US07709021B2
The invention relates to a wound dressing comprising a microbial-derived cellulose for treatment of specific types of chronic wounds, including pressure sores, venous and diabetic ulcers. The wound dressing is capable of donating liquid to dry substrates is also capable of absorbing exudating wounds.
US07709018B2
A composite material comprising: (i) hyaluronic acid and/or hyaluronic acid derivatives, (ii) demineralised bone and/or biocompatible partially or totally demineralised bone tissue matrix and/or biocompatible and bioresorbable ceramic materials. This material preferably associated with at least one layer comprising a hyaluronic acid derivative may be used in the preparation of bone substitutes or grafts for the regeneration or formation of bone tissue in surgery.
US07709016B2
The object of the present invention is to impart lasting excellent insect proof property to boards.According to the present invention, an insecticidal treatment liquid which contains an insecticide in an aqueous dispersion of colloidal silica is applied to the surface of a coat on a substrate applied with coating. Namely, according to the present invention, since a coating composition is not used to fix the insecticide to the surface of the coat, the insecticide is not diluted with a resin in the coating composition.
US07709015B2
Disclosed is a polyol-in-silicone emulsion consisting essentially of: (i) an alkyl dimethicone copolyol having an HLB of from about 4 to about 6, and a molecular weight of from about 10,000 to about 20,000, wherein the alkyl group is made of about 10 to about 22 carbons; and (ii) a polyol, wherein the weight ratio of the alkyl dimethicone copolyol to the polyol is from about 100:1 to about 2:8; methods to make such a polyol-in-silicone emulsion, as well as an anhydrous personal care composition comprising by weight: (a) from about 0.01% to about 15% of an alkyl dimethicone copolyol having an HLB of about 4-6, and a molecular weight of from about 10,000 to about 20,000, wherein the alkyl group is made of about 10 to about 22 carbons; (b) from about 0.01% to about 35% of a polyol, wherein the weight ratio of the alkyl dimethicone copolyol to the polyol is from about 100:1 to about 2:8; and wherein the composition is substantially free of water.
US07709011B2
Cosmetic or pharmaceutical preparations comprising an oxalkylated polyglycerol ester of the formula (1) in which A is a group of the formula —C2H4— or —C3H6—, B is hydrogen or a group of the formula —COR, where at least one symbol B is a group of the formula —COR, R is C7-C21-alkyl or C2-C21-alkenyl, n is a number from 1 to 30 and x, y and z are numbers from 0 to 100, where the sum of x, y and z is 50 to 250.
US07709010B2
The present invention relates to pharmaceutical compositions comprising virus-like particles (VLPs) of HPV, said VLPs adsorbed to an aluminum adjuvant, and an ISCOM-type adjuvant comprising a saponin, cholesterol, and a phospholipid. In preferred embodiments, the aluminum adjuvant comprises amorphous aluminum hydroxyphosphate sulfate. Another aspect of the invention provides multi-dose HPV vaccine formulations comprising HPV VLPs and an antimicrobial preservative selected from the group consisting of: m-cresol, phenol and benzyl alcohol. Also provided are methods of using the disclosed pharmaceutical compositions and formulations to induce an immune response against HPV in a human patient and to prevent HPV infection.
US07709009B2
The invention includes a GAS antigen, GAS 40, which is particularly suitable for use either alone or in combinations with additional GAS antigens, such as GAS 117, GAS 130, GAS 277, GAS 236, GAS 40, GAS 389, GAS 504, GAS 509, GAS 366, GAS 159, GAS 217, GAS 309, GAS 372, GAS 039, GAS 042, GAS 058, GAS 290, GAS 511, GAS 533, GAS 527, GAS 294, GAS 253, GAS 529, GAS 045, GAS 095, GAS 193, GAS 137, GAS 084, GAS 384, GAS 202, and GAS 057.
US07709007B2
Attenuated respiratory syncytial virus (RSV) and vaccine compositions thereof are produced by introducing specific mutations associated with attenuating phenotypes into wild-type or RSV which is incompletely attenuated by cold-passage or introduction of mutations which produce virus having a temperature sensitive (ts) or cold adapted (ca) phenotype. Alternatively, recombinant RSV and vaccine compositions thereof incorporate attenuating and other mutations specifying desired structural and or phenotypic characteristics in an infectious RSV. Recombinant RSV incorporate desired mutations specified by insertion, deletion, substitution or rearrangement of a selected nucleotide sequence, gene, or gene segment in an infectious RSV clone. The immune system of an individual is stimulated to induce protection against natural RSV infection, or multivalently against infection by RSV and another pathogen, such as PIV, by administration of attenuated, biologically derived or recombinant RSV.
US07708991B2
The present invention relates to compositions and methods for treating cancer, especially epithelial and eutopic cancers using inhibitors of H-HCG or β-H-HCG, as well as vaccines for use in oncostasis or reducing the likelihood of recurrence of cancer after remission. In addition, the present invention provides a method for reducing the likelihood that a woman will become pregnant or that an unwanted pregnancy may be terminated.
US07708989B2
The invention provides methods of treating and/or preventing vascular diseases characterized by nitric oxide insufficiency by administering a therapeutically effective amount of at least one nitrosated angiotensin-converting enzyme inhibitor, nitrosated beta-adrenergic blocker, nitrosated cholesterol reducer, nitrosated calcium channel blocker, nitrosated endothelin antagonist, nitrosated angiotensin II receptor antagonist, nitrosated renin inhibitor, and optionally at least one compound used to treat cardiovascular diseases and/or at least one antioxidant, or a pharmaceutically acceptable salt thereof, and/or at least one compound that donates, transfers or releases nitric oxide, elevates endogenous levels of endothelium-derived relaxing factor, stimulates endogenous synthesis of nitric oxide or is a substrate for nitric oxide synthase. The antioxidant may preferably be a hydralazine compound or a pharmaceutically acceptable salt thereof. The compound that donates, transfers or releases nitric oxide, elevates endogenous levels of endothelium-derived relaxing factor, stimulates endogenous synthesis of nitric oxide or is a substrate for nitric oxide synthase may preferably be isosorbide dinitrate and/or isosorbide mononitrate. The vascular diseases characterized by nitric oxide insufficiency include a cardiovascular disease and a disease resulting from oxidative stress.
US07708988B2
The present invention discloses compositions and methodologies for the utilization of probiotic organisms in therapeutic compositions. More specifically, the present invention relates to the utilization of one or more species or strains of lactic acid-producing bacteria, preferably strains of Bacillus coagulans, for the control of gastrointestinal tract pathogens, including antibiotic-resistant gastrointestinal tract pathogens, and their associated diseases by both a reduction in the rate of colonization and the severity of the deleterious physiological effects of the colonization of the antibiotic-resistant pathogen. In addition, the present invention relates to the utilization of therapeutic compounds comprised of lactic acid-producing bacteria and anti-microbial agents such as antibiotics, anti-fungal compounds, anti-yeast compounds, or anti-viral compounds. The present invention also discloses methodologies for: (i) the selective breeding and isolation of probiotic, lactic acid-producing bacterial strains which possess resistance or markedly decreased sensitivity to anti-microbial agents (e.g., antibiotics, anti-fungal agents, anti-yeast agents, and anti-viral agents); and (ii) treating or preventing bacteria-mediated infections of the gastrointestinal tract by use of the aforementioned probiotic bacterial strains with or without the concomitant administration of antibiotics. While the primary focus is on the treatment of gastrointestinal tract infections, the therapeutic compositions of the present invention may also be administered to buccal, vaginal, optic, and like physiological locations.
US07708979B2
Thermogelling polymers are described containing poly (n-isopropyl acrylamide). Solutions of this polymer, copolymers or mixtures of the polymer with a second polymer such as poly(ethylene glycol), poly (vinyl pyrrolidone) or poly(vinyl alcohol) are liquids at room temperature and solids at body temperature. Thus, also provided are methods of implanting a hydrogel into a mammal by injecting the solution as a liquid at a temperature below body temperature into a selected site in the mammal at a temperature below body temperature, which then undergoes thermal phase transition to form a solid hydrogel in situ in the body as the implant warms to body temperature. Methods for using these thermal gelling materials in various applications including nucleus pulposus replacement/augmentation, wound care, disk replacement, cartilage replacement, joint replacement, surgical barriers, gastrointestinal devices, cosmetic and reconstructive surgery, and breast enlargement are also provided.
US07708978B2
The present invention relates to an active targeted water-solubility macromolecule polymer, conjugate with interferon and pharmaceutical composition comprising the conjugate. The targeted agent includes, for example, glucose, galatose and the like, as well as their derivates. The conjugate of the present invention is well in water-solubility and have long physiological cycle half-life period, and have specific recognition to pathology organize, improved and increased medication effect of interferon to Hepatitis B, Hepatitis C etc. infectivity sickness and cancer, infect complication etc.
US07708977B2
A method for diagnosing decreased vascular function is disclosed. The method includes assaying the number of endothelial progenitor cells. A method for detecting increased cardiovascular risk is also disclosed, as is a method for diagnosing atherosclerosis. In one example, the methods include assaying the number of endothelial progenitor cells. A method for treating a subject with decreased vascular function is disclosed. The method includes administering a therapeutically effective amount of endothelial progenitor cells to the subject. In one embodiment, the subject has atherosclerosis.
US07708976B2
A novel small pore (metallo)aluminophosphate molecular sieve is disclosed. The as-synthesized material has an X-ray diffraction pattern including the lines listed in Table 1 and is produced in the presence of fluoride ions and 4-dimethylaminopyridine as structure directing agent. The silicoaluminophosphate material has methanol conversion activity and n-hexane cracking activity.
US07708972B2
Method for producing sodium carbonate, according to which an aqueous sodium chloride solution (5) is electrolyzed in a membrane-type cell (1) from which an aqueous sodium hydroxide solution (9) is collected, and carbonated by direct contact with carbon dioxide (15) to form a slurry of crystals of a sodium carbonate (16), and the slurry or its mother liquor is evaporated (3) to collect sodium carbonate (18).
US07708967B2
The invention provides a process for disposal of mercaptans, the process comprising the steps of: (a) contacting a feed gas stream comprising mercaptans with liquid sulphur in a sulphide producing zone at elevated pressure and at a temperature in the range of from 300 to 450° C. to obtain a liquid stream comprising sulphur and sulphide compounds; (b) optionally separating the liquid stream obtained in step (a) into a first liquid phase enriched in liquid sulphur and a second liquid phase enriched in sulphide compounds; (c) combusting at least part of the sulphide compounds at elevated temperature in the presence of an oxygen-containing gas in a sulphur dioxide generation zone using a sulphide burner to which burner oxygen-containing gas is supplied, whereby at least part of the sulphide compounds is converted to sulphur dioxide to obtain a gas stream comprising sulphur dioxide.
US07708964B2
Pollution control substances may be formed from the combustion of oil shale, which may produce a kerogen-based pyrolysis gas and shale sorbent, each of which may be used to reduce, absorb, or adsorb pollutants in pollution producing combustion processes, pyrolysis processes, or other reaction processes. Pyrolysis gases produced during the combustion or gasification of oil shale may also be used as a combustion gas or may be processed or otherwise refined to produce synthetic gases and fuels.
US07708962B2
A process for the separation and purification of hafnium and zirconium.
US07708959B2
A sterilization system for use in association with a filler device configured for filling at least one of rigid and flexible containers comprising a sterilization chamber and a sterilant supply assembly. The sterilization chamber includes a housing, an inlet into the housing, an outlet from the housing and a product retainer assembly. These components define a cavity within which to position a portion of a fitment. The sterilant supply assembly comprises a steam generating system having a steam supply conduit extending therefrom and a joint mixing conduit coupled with the inlet into the housing of the sterilization chamber, a hydrogen peroxide storing system and a member for metering liquid phase hydrogen peroxide from the hydrogen peroxide storing system into the steam supply conduit for mixing therewith, and, in turn, introduction thereof into the cavity of the sterilization chamber.
US07708956B2
A method and an apparatus for removing sulfur hydrocarbon compounds from a naphtha stream and for simultaneously removing sulfur hydrocarbon compounds from two streams is described. A separator vessel having a top, a bottom, a primary feed inlet and a co-feed inlet is disposed vertically above the primary feed inlet. The separator vessel further includes a catalyst bed disposed between the co-feed inlet and the top. A primary feed stream comprising sulfur hydrocarbon compounds is delivered through the effluent inlet and a vaporized co-feed stream that also comprises sulfur hydrocarbon compounds is delivered through the co-feed inlet. Vaporized sulfur hydrocarbon compounds from the primary feed stream with the vaporized co-feed stream pass upwardly through the desulfurization catalyst bed. Sulfur hydrocarbon compounds from both primary feed and co-feed stream are at least partially converted to hydrogen sulfide and non-sulfur containing hydrocarbons in the catalyst bed.
US07708948B2
The invention relates to a test system for analyzing body fluids of the type comprising a test element tape carrying a plurality of test elements, a tape deflector for the test element tape for the selective application of body fluid, and a light source as well as a detector for optically analyzing test elements to which body fluid has been applied. The tape deflector has a rotatable optical element which acts as a deflection roller during transport of the test element tape. The optical element is positioned in the optical path between the light source and the detector.
US07708946B1
A device for automation of biological and medical tests wherein test subjects or specimens that are placed in test vessels are subsequently treated by different liquid reagents, including: at least two test vessels of dimensions providing accommodation of specimens, a hydraulic gravity feeding system to deliver the liquid reagents into the two test vessels, a hydraulic gravity discharging system to remove waste liquid or spent reagents from the test vessels and directing them into an apparatus for accommodation of the such waste liquid or spent reagents, and a control system operating the device. A mechanical system is provided for agitating the test vessels.
US07708934B2
In a method for manufacturing a precursor ceramic by pyrolysis of elementorganic precursor polymers, carbon nanotubes are bonded to the precursor ceramic and the bonding is performed in such a way that the quantity of free carbon forming in the decomposition of the elementorganic precursor polymers is adjusted in such a way that there is a stoichiometric or moderately hypostoichiometric carbon concentration in the precursor ceramic.
US07708928B2
Medical device balloons are formed from a tubular parison by a process or apparatus which establishes a controlled location (initiation zone) on the parison where radial expansion is initiated. Initiation within the initiation zone is achieved by heating the parison in that location to a higher temperature than the remainder of the parison for at least a portion of the blowing time. A variety of apparatus configurations are provided, some of which allow for the size and location of the initiation zone to be readily reconfigured. Balloons can also be modified, post-blowing, using heating apparatus and methods described.
US07708925B2
An apparatus for heating and setting elements of a stent. The apparatus is a mandrel having a central core cylinder with an outer surface including a plurality of raised forms and gaps in-between the raised forms. The mandrel also includes a first and second outer cylinder, each having a curved radial end with a cut-out design similar to the shape of the plurality of raised forms. Once a stent is placed on the central core cylinder, the first and second outer cylinders are positioned on the central core cylinder such that the curved radial ends of the first and second outer cylinders align with the plurality of raised forms, shaping the stent.
US07708921B2
A cast web formed on a support in a casting process is peeled off the support by a first roller in a peeling and conveying process. As being peeled by the first roller, the cast web forms a film, and conveyed through a second roller to a tenter drying process. The peeling and conveying process has a length from a peeling position to a holding position of the film by clips. The length is set to be 10% to 80% of the width of the cast web. The first and second rollers are concave rollers. A couple of blowers are disposed at the end of the peeling and conveying process, to blow the lateral sides of the film in laterally outward directions of the film, to stretch curls in the lateral sides of the film.
US07708903B2
The present invention relates to fluoroolefin compositions. The fluoroolefin compositions of the present invention are useful as refrigerants or heat transfer fluids and in processes for producing cooling or heat. Additionally, the fluoroolefin compositions of the present invention may be used to replace currently used refrigerant or heat transfer fluid compositions that have higher global warming potential.
US07708901B2
The invention relates to magnetorheological materials comprising at least one non-magnetisable carrier medium and magnetisable particles contained therein, in addition a combination of magnetic and non-magnetic inorganic materials and/or composite particles thereof being contained.
US07708898B2
A system for removing particles from a slurry tank includes a filtering device and a controller. The filtering device collects and removes particles deposited within the slurry tank and the controller controls the placement and movement of the filtering device with respect to the slurry tank.
US07708896B2
An ion elution unit generates metal ions by applying a voltage between electrodes. Terminals are formed integrally to the electrodes. An interval between the electrodes becomes narrower from an upstream side to a downstream side with respect to a water current flowing through an inside of a casing of the ion elution unit. Terminals that are so laid as to run from the electrodes out of a casing of the ion elution unit are disposed on an upstream side with respect to a water current flowing through an inside of the casing.
US07708882B2
A vertical membrane module unit is allowed to be installed even at a place with a low ceiling. A housing containing a vertical membrane module unit is held by a housing holder. The housing holder holds the housing tiltably such that the housing can be positioned with the longitudinal direction of the membrane module unit being substantially vertical when treated water is extracted, and the housing can be positioned with the longitudinal direction of the membrane module unit being substantially horizontal when the membrane module unit is removed from the housing.
US07708870B2
To provide an electrophoresis method being capable of rapidly analyzing a protein in a native state without carrying out a heat-denaturing pretreatment step, and having even higher sensitivity. The electrophoresis method of the present invention is useful for proteosome analysis and medical diagnosis.
US07708867B2
The present invention provides a gas diffusion electrode having: an electrode substrate; and a catalyst layer containing a hydrophilic catalyst and a hydrophobic binder, which is carried on the electrode substrate, wherein the electrode substrate contains at least one carbon material selected from a carbon cloth, a carbon paper, a foamed carbon material, and a sintered carbon material.
US07708856B2
A method to control the post sinter distortion of hot pressing sintered multilayer ceramic laminate by placing a non-densifying structure in the green ceramic laminate prior to sintering. One or more non-densifying structures are placed on one or more ceramic greensheets which are then stacked and laminated to form a green ceramic laminate. The laminate is then sintered and the non-densifying structure will control the dimensions of the hot pressed multilayer ceramic substrate. The method can be used to control post sinter dimensions in MLC substrates manufactured as either single or multi-up substrates by placing the non-densifying structure in the kerf area between the individual product ups prior to sintering.
US07708854B2
Explained, inter alia, is a method in which a workpiece (52) to be processed is fastened to a work carrier (10) by means of a solid (62). The work carrier (10) is made of a porous material, e.g. of porous ceramic. This processing method permits simple manipulation of the wafer during the processing. In addition, the workpiece (52) can be easily separated from the work carrier (10) using a solvent.
US07708850B2
In the manufacturing method of the laminated metal plate, a fluorine resin film is used as a plastic film. Prior to a flame treatment, a joint surface of the metal plate is heated with a direct flame of 900° C. to 1200° C. for 1 to 5 seconds so that the joint surface is preheated to 40° C. to 70° C. After that, the joint surface of the metal plate is heated to 250° C. to 450° C. by the follow-on flame treatment.
US07708846B2
For a group of nickel-based superalloys, improved properties have been obtained by stabilizing at increased temperature for a reduced time relative to prior art specifications. In particular, improved creep properties have been obtained with a one-hour 1800° F. stabilization relative to a prior art four-hour 1500° F. stabilization.
US07708840B2
Method of cleaning dishes in an automatic dishwashing machine comprising providing film material consisting essentially of an ethoxylated poly(vinylalcohol) material enclosing a dishwasher detergent composition to an automatic dishwashing machine.
US07708837B2
This invention relates to a dishwasher (1) comprising a biosensor (7) and a control method which provides an efficient, clean and hygienic washing wherein the main water supply and washing water are microbiologically analyzed in the phases of the program, and the washing water temperature and circulation period are adjusted in each phase.
US07708828B2
A polycrystalline granulated silicon is made of particles which have a density of greater than 99.9% of the theoretical solid density and therefore have a pore content of less than 0.1% and have a surface roughness Ra of less than 150 nm.
US07708827B2
A highly pure, replaceable wear insert and a process for manufacturing the same use a group of materials which is suitable for meeting the requirements of high temperature semiconductor technology processes and is chosen at the same time for producing thin layers or components therefrom. The materials are compacted and purified at high temperatures in compression molds and the products so produced are put to their intended use. The substantially thin-walled and crucible-shaped, always highly pure components, which are predominantly made of expanded graphite, are employed as a wear insert for protecting graphitic support crucibles from reactive attack by quartz glass crucibles in semiconductor technology processes at temperatures above 500° C.
US07708823B2
The present invention relates to semitransparent interference pigments having a neutral mass tone comprising a substrate and a coating comprising metallic tin and additionally at least one metal oxide, to a process for the preparation of these pigments, and to the use thereof.
US07708816B2
A carbon nanotube filter. The filter including a filter housing; and chemically active carbon nanotubes within the filter housing, the chemically active carbon nanotubes comprising a chemically active layer formed on carbon nanotubes or comprising chemically reactive groups on sidewalls of the carbon nanotubes; and media containing the chemically active carbon nanotubes.
US07708815B2
Embodiments of the invention relate to a composite hydrogen storage material comprising active material particles and a binder, wherein the binder immobilizes the active material particles sufficient to maintain relative spatial relationships between the active material particles.
US07708803B2
The invention provides methods and apparatuses for removing additional aerosols and in some cases additional particulate matter from a gas stream, wherein a certain portion of such aerosols and particulate matter has already been removed using a primary aerosol and particulate collection device. In some embodiments, the invention includes a method for removing additional aerosols from a gas stream, including passing a gas stream having a plurality of aerosols through a gas duct; removing a first portion of the plurality of the aerosols using a primary aerosol collector; passing the gas steam through a screen; collecting at least a second portion of the plurality of aerosols on the screen; and cleaning a portion of the screen outside of the gas duct. The invention also provides various apparatuses for use in performing the method of the invention.
US07708780B2
Instrumentation for implanting a cervical disc replacement device includes cervical disc replacement trials for determining the appropriate size of replacement device to be implanted, an insertion plate for maintaining the elements of the replacement device in fixed relation to one another for simultaneous manipulation, an insertion handle for attachment to the insertion plate for manipulation of the elements, an insertion pusher for releasing the insertion handle from the insertion plate, a drill guide that cooperates with the insertion plate to guide the drilling of tap holes for bone screws to be placed through bone screw holes in the flanges of the replacement device, clips that are applied to the flanges after placement of the bone screws to resist screw backout, and a clip applicator for applying the clips to the flanges.
US07708772B2
An apparatus and method is provided for stenting bifurcated vessels. A proximal angled stent is configured for implanting in a side-branch vessel wherein the proximal angled stent has an angulated portion that corresponds to the angle formed by the intersection of the side-branch vessel and the main vessel so that all portions of the side-branch vessel at the bifurcation are covered by the proximal angled stent. A main-vessel stent is provided for implanting in the main vessel, wherein the main-vessel stent has an aperture or stent cell that aligns with the opening to the side-branch vessel to permit unobstructed blood flow between the main vessel and the side-branch vessel. Side-branch and main-vessel catheter assemblies are advanced over a pair of guide wires for delivering, appropriately orienting, and implanting the proximal angled stent and the apertured stent.
US07708767B2
An orthopedic screw with an internal bore and mating driver has a bioabsorbable polymer component. To increase the torque tolerance of the screw and to minimize the likelihood of the driver stripping inside the bore of the screw, the screw and driver are heat treated together to shrink fit the screw onto the driver thereby increasing the driver-to-screw contact and distributing the loading force over a greater area to protect against material failure. The heat treatment involves heating the screw to an elevated temperature and holding that temperature for a period to promote stress relaxation and/or crystallization of the material.
US07708763B2
Minimally invasive methods and devices for introducing a spinal fixation element into a surgical site in a patient's spinal column are provided. In one embodiment, a dissection tool is provided for separating muscles along a muscle plane without causing damage to the muscles. The dissection tool can also include a lumen extending therethrough for receiving a guide wire. The tool allows the guide wire to be positioned relative to a vertebra, and once properly positioned, the tool can be removed to allow a spinal anchor to be delivered along the guide wire and implanted into the vertebra.
US07708757B2
A medical forceps has a shaft, a handle at the proximal end of the shaft, which handle has at least one movable grip part which is pivotable about a pivot axis, at least one movable tool at the distal end of the shaft, and a force transmission element, which runs in the direction of the longitudinal axis of the shaft and is axially movable and with one end is in operative connection with the at least one movable tool and with the other end is in operative connection with the at least one movable grip part. The force transmission element is connected to a slide which is guided linearly with an exact fit in a sliding bearing and is axially movable in the direction of the force transmission element, the slide being connected to the movable grip part by means of an articulated lever, which is articulated with one end on the slide and with another end on the movable grip part.
US07708747B2
Disclosed is a method and device for suturing tissue and implanting prosthetic grafts, the device includes 1) at least one flexible cannula having a means to remotely manipulate the configuration of its distal end, and 2) a suction capsule component that may be incorporated or fit within or about the flexible cannula. The flexible cannula and suction capsule component are of a size that allows them to be inserted, independently or as a unit, into a natural body orifice or small surgical incision. The suction component may be used to draw tissue into an opening in the suction capsule component, enabling the at least one needle to be advanced through the at least one flexible cannula thereby passing through the tissue held by the at least one opening in the suction capsule component and thereby delivering the attached suture to the tissue.
US07708733B2
A method for treating a bone body comprises inserting a probe having at least one active electrode into the target tissue and applying a voltage difference between an active electrode and return electrode to ablate the tissue. The method is particularly directed to removing tumors in a bone body and or removing cancellous bone in a bone body. The bone body may be a vertebral body. An apparatus includes a plurality of active electrodes and a distal section including two bends. The bends serve to prevent the active electrodes from impinging upon the shaft of an introducer needle. Also, a kit includes an electrosurgical probe, an electrosurgical generator, an introducer needle, and a fluid connector to connect the introducer needle to a fluid source such that liquid may be supplied to the target site during an application.
US07708731B2
An electrotransport device (10) for delivering therapeutic agents includes an adjustable voltage boos multiple controller (100, 200) for boosting the voltage from a power source (102, 202) to a working voltage Vw having a value just sufficient to provide the desired therapeutic current level II through the electrodes (108, 112), at least of which contains the therapeutic agent to be delivered.
US07708729B2
The invention concerns a garment (1) comprising an absorbent section (2) and a waist belt (3) attached directly or indirectly thereto. The waist belt has two belt portions (7, 8) extending on either side of said absorbent section for securing to each other around a wearer of the garment The particular handling characteristics of the belt parts of the waist belt (3) are significantly improved by manufacturing a belt stiffness of between 25 g and 90 g as measured by the modified version of test ASTM D 4032-82 CIRCULAR BEND PROCEDURE.
US07708727B2
A personal care article (20) has a longitudinal-direction (22), a relatively shorter, lateral cross-direction (24), a first end-section (72), a second end-section (72a), and an intermediate-section (76). The article has been operatively connected in facing relation with a wrap member (98), and the article has been folded about a first, laterally extending supplemental-fold-region (64). The article and a corresponding section of the wrap member have been folded about a second, laterally extending supplemental-fold-region (66). A preliminary-folded article (82) and a corresponding, preliminary-folded wrap member have been provided after the article has been folded about both the first and second supplemental-fold-regions. The preliminary-folded article and wrap member have also been folded along a laterally extending, composite-fold-region (96a) of both the preliminary-folded article and wrap member, to provide a composite-folded, wrapped article (114).
US07708721B2
A vascular access needle assembly is provided. The needle assembly includes a housing interconnected with a needle. The housing and the needle have slots along their lengths which are aligned to form a slot extending along the entire needle assembly. A sheath interconnected with the needle extends partially about the needle and includes a slot. The vascular access needle, with the needle point exposed and needle slot closed, can be inserted into the blood vessel of a subject and a guide wire can be inserted into the blood vessel through the needle assembly. The sheath is then moved to cover the needle point and to expose the needle slot so that the guide wire can be lifted through the needle, sheath and housing slots and the vascular access needle assembly removed, leaving the guide wire in the subject. The device can also be used as a wire introducer for catheters. The vascular needle assembly can also be used as a biopsy needle for obtaining biopsy tissue wherein the edges of one or both of the needle slot and sheath slot are sharpened for cutting tissue.
US07708720B1
A catheter terminus protective system comprising a base panel having a pair of adjoining flaps, an adhesive patch on at least one of the flaps for securing at least one catheter terminus from which a catheter line extends, the flaps being relatively moveable between secured closed positions in which they form a protective enclosure for the catheter terminus, and free open positions in which they allow manual access to said catheter terminus. An original catheter line extends from the protective enclosure when the flaps are in the closed positions and may be replaced by an alternative catheter line when the flaps are opened. The flaps are constituted by a fluid impermeable facing and a fluid absorbent backing in superposition.
US07708719B2
A medicament container, medicament dispensing kit and packaging process that minimizes exposure of the medication to oxygen to prevent degradation of the medication are disclosed.
US07708718B2
A radiation shielding syringe carrier comprising a top cap, a main body and a needle shield, all formed from a radiation dense material. The main body preferably includes a syringe shield shaped to be threadably engaged to the bottom of the carrier. Preferably a separate top cap and shipping cap are provided.
US07708717B2
Some embodiments of a medical infusion pump system include a pump device and a removable controller device. When the pump device and the removable controller device are removably attached to one another, the components may provide a portable infusion pump unit to dispense medicine to a user. In particular embodiments, the removable controller device includes a user interface to readily provide information, for example, about the operation of the pump.
US07708706B2
The invention is a synchronous impact table (the impact table). The impact table includes a support system having a control system therein, a power system coupled to the control system, a lift system coupled to the power system and the support system, and a patient support system coupled to the lift system. By providing a synchronous percussion wave to a user continuously over time, body and jaw alignment can be enhanced, soft connective tissue can return to its natural position, and body fluids can again flow and balance more naturally.
US07708705B2
A device (4440), system and method may sense and/or analyze in-vivo pressure or stress, and may in addition sense other data such as for example, image data. An in-vivo device (4440) may include a stress or pressure sensor (4443), and possibly an additional sensor, such as an image sensor, a pH sensor, etc. In one example the stress or pressure sensor (4443) is connected to a shell (4444) of the device.
US07708699B2
A method including measuring time periods in which a reflex point of a subject is struck and a reflex response is observed. A method including determining a resting metabolic rate of a subject by applying the Kail-Waters equation. An apparatus including a striking instrument capable of delivering a kinetic energy to a reflex point of a subject; and a measurement instrument capable of being coupled to a subject and measuring a reflex response. A machine-readable storage medium containing executable program instructions which when executed cause a digital processing system to perform a method including determining time periods in which a reflex point is struck and a reflex response is observed. A machine-readable storage medium containing executable program instructions which when executed cause a digital processing system to perform a method including determining a resting metabolic rate of a subject by applying the Kail-Waters equation.
US07708692B2
An ultrasonic diagnostic apparatus includes: a transmitting section for driving an ultrasonic probe sending out an ultrasonic transmitted wave toward a body tissue of an organism; a receiving section for receiving an ultrasonic reflected wave, produced by getting the transmitted wave reflected by the body tissue, through the probe; a phase detecting section for detecting the phase of the reflected wave; and a computing section for calculating the magnitudes of positional displacement at multiple measuring points on the body tissue based on a signal obtained by the detecting section and calculating the greatest thickness difference between two of the measuring points and/or an elastic property based on the magnitudes of positional displacement. The computing section calculates the maximum and minimum thicknesses or thickness variations between the two points based on the magnitudes of positional displacement at the two points during a part of one cardiac cycle, and calculates the greatest thickness difference and/or elastic property as the difference between the maximum and minimum values.
US07708691B2
An ultrasonic image scanning system for scanning an organic object includes a container for containing a coupling medium for transmitting an ultrasonic signal to the organic object disposed therein whereby a simultaneous multiple direction scanning process may be carried out without physically contacting the organic object. The ultrasonic image scanning system further includes ultrasound transducers for transmitting the ultrasonic signal to the organic object through the coupling medium without asserting an image deforming pressure to the organic object. These transducers distributed substantially around a two-dimensional perimeter of the container and substantially at symmetrical angular positions at approximately equal divisions of 360 degrees over a two-dimensional perimeter of the container. The transducers are further movable over a vertical direction alone sidewalls of the container for a real time three dimensional (3D) image data acquisition. The container further includes sidewalls covered with a baffle layer for reducing an acoustic reverberation.
US07708689B2
An endoscope is described in which the diameter of the image relay assembly is less than that of the objective lens assembly. An endoscope sheath is also described for sheathing the endoscope and housing or directing optical fibers for use in illuminating the endoscope view of view. An endoscope-sheath system is further described comprising the combination of the endoscope and the endoscope sheath in eccentric alignment to reduce fluid flow impedance between the two.
US07708681B2
A porous bed centrifuge for continuous separation of immiscible liquids, for example water and mineral oil/petroleum, obtained by a modification to conventional disk centrifuges for increasing their efficiency, wherein the disks have been substituted by a filling of solid particles that act as a filtrating and coalescent bed.
US07708680B2
The present invention relates to a method and an arrangement in a cardboard creasing machine performing creases on a cardboard blank web. The web has a width of at least two lanes of blanks in parallel to each other and comprise in at least one zone per pair of lanes an area where intentional creases on both are made transversally to a feeding direction of the machine. The crease-lines are on the male side interrupted to provide a longitudinal seal strip to an edge of each blank to become. The cardboard web is in a limited area of such an interruption intentionally and positively lifted and supported from the side of a female crease die to a level in between being in line with to being above an outermost surface of a female crease die roller of the machine.
US07708677B2
The invention provides a plastic-sheathed roller, typically a tension roller of plastic for a belt drive. The roller comprises a wheel comprising an inner ring and an outer ring that are connected through radially oriented ribs arranged spaced apart on a periphery and through a central web. The wheel is mounted for rotating through a rolling bearing on a carrier element, while being supported through a running surface on a belt of the belt drive, and injection gates for injection molding are arranged distributed on a lateral surface while being spaced apart angularly non-uniformly from one another.
US07708672B2
A weight system includes a selector configured to selectively couple incremental weights that extend through a weight stack to a weight lift.
US07708670B2
A seated row exercise system including an exercise cycle assembly that detachably connects to a chair frame of a chair; and, an elongated support assembly. The exercise cycle assembly includes a main frame having a first end portion detachably connectable to a frame element of a chair frame, the main frame including a plurality of support legs for supporting the exercise cycle assembly relative to the floor; and, a pedal assembly securely connected to the main frame. The elongated support assembly includes a substantially vertical support member secured to the main frame; and, a pulley housing assembly attached to the vertical support member for supporting a cable assembly.
US07708668B2
A stationary exercise device with flexible support elements may include a frame with a base portion. A crank system with crank arms is coupled to and supported by the frame. Right and left pivotal linkage assemblies may each have an arcuate motion member and a foot support member. The arcuate motion member may be coupled to the frame. The foot support member may be coupled to the arcuate motion member. The arcuate motion member may be oriented in a generally vertical position and the foot support member may be oriented a generally horizontal position. Flexible element coupling systems couple the right and left foot support members to the crank system.
US07708664B2
A drive unit for oscillatingly driven mowing sickles has a first transmission unit {1} with a first housing (5) defining a first axis (6). A rotor (7) is rotationally supported in the first housing (5) around the first axis (6). A first internal gear wheel (10) is fixed in the first housing (5) and provided with internal teeth. A toothed pinion (14) is rotationally supported in the rotor (7) around a second axis (12). The second axis (12) is radially off-set to the first axis (6). The toothed pinion (14) forms the output element of the drive unit and meshes with the first internal gear wheel (10). A second transmission unit (2) has an output (34) non-rotationally connected to the rotor (7) of the first transmission unit (1). The second transmission unit (2) is formed as a step-down gear. A motor (4), with an output shaft (45), rotationally drives the second transmission unit (2). The rotational speed N1 is reduced by the second transmission unit (2), formed as a step-down gear, to the rotational driving speed N2 of the first transmission unit (1).
US07708663B2
A transmission includes a ring gear driven by a first primary gear train, a carrier driven by a second primary gear train and a sun gear driven by a third primary gear train. Clutches are utilized to lock and unlock the ring gear, carrier and sun gear. When locked each rotate at the same speed and the torques are added together at an output shaft to provide a high torque low speed output from the transmission. As the transmission accelerates the clutches are disengaged allowing the ring gear, carrier and sun gear to rotate separately and achieve higher speeds, providing a continuous output from high torque to high speed operation.
US07708654B2
A golf ball with a controlled moment of inertia and controlled spin rate is disclosed. The ball has an intermediate layer positioned between the core and the cover and the intermediate layer has a reduced specific gravity. Preferably, this reduction is less than about 30% in specific gravity and the reduction in the coefficient of restitution is less than about 2%.
US07708652B2
A golf club (40) has a golf club head with a large mass, relatively short club length and a moment of inertia about the Izz axis through the center of gravity of the golf club head greater than 5000 grams-centimeters squared. The golf club head (42) preferably has a volume ranging from 400 cubic centimeters to 470 cubic centimeters. The golf club head (42) preferably has a moment of inertia about the Ixx axis through the center of gravity of the golf club head greater than 3000 grams-centimeters squared. The golf club (40) preferably has an inertia ratio greater than 0.0019.
US07708649B2
The present invention relates generally to the field of training aids and methods for the development and improvement of a proper golf swing. Specifically, the present invention relates to training aids and methods for the development of proper golf swings that aid the student in learning the proper swing mechanics for hitting golf shots straight, hitting golf shots that curve slightly to the right, and hitting golf shots that curve slightly to the left. The training aid may be used to improve golf shots used during full shots, putting, pitching, and chipping. The present invention may be well suited for beginning players to teach proper techniques.
US07708643B2
In accordance with one aspect of saving audio source identifiers for soundtracks in a gaming system, an audio track is obtained from an audio source and the audio track is saved so that a copy of the audio track is available when the audio source is no longer accessible to a game console. The audio track is at least part of a user-created soundtrack and/or a user-selected soundtrack. The identifier of the audio source is also saved, and when a database containing meta data associated with the audio track is available, the meta data associated with the audio track is obtained from the database, based at least in part on the identifier saved on the storage device, and the obtained meta data is stored.
US07708641B2
When a selected character 50 in possession of a ball 51 enters a centering area, a button switch image 61 for “centering” is displayed on a second LCD 12 provided with a touch panel. If the player touches the button switch image 61, the selected character 50 makes a “centering” pass. The target point for the centering pass varies depending on which portion of the button switch image 61 the player touches. Each point in the button switch image 61 corresponds to a point within the centering area in the game field. This adds variety to the action of a player object by a simple operation, thereby making the game more fun.
US07708628B2
A gaming device for providing awards to players. The gaming device includes an award distributor such as an award wheel having a plurality of sections, each of the sections having or defined by first and second coordinates, a plurality of award symbols included on the sections, an illumination device associated with the sections, a section indicator associated with the award wheel and a processor in communication with the award wheel. The gaming device determines the first coordinate of one of the groups of sections. Then, the gaming device or player spins the award wheel and the section indicator determines the second coordinate of one of the sections in the group, which indicates the section. The gaming device provides any award or symbol to the player that is associated with the indicated section.
US07708626B2
An air supply device for an automotive seat includes an air duct which is arranged at the delivery side of a fan and has at least one air outlet opening provided in the upper region of the seat for supplying the head, shoulder and neck region of a seat occupant with a flow of air. A heating element is arranged in the air duct between the fan and the air outlet opening, and the air supply device has at least one sensor for detecting a parameter value as a function of which the flow of air emerging from the air outlet opening is controlled. In order to provide the air supply device with a flow of air which can be controlled in a more universal manner, the sensor is arranged inside the air duct between the air outlet opening and the heating element.
US07708625B2
An inlet and/or outlet air hood comprising vertical storm louvers is provided that is particularly well suited for use on a Mobile Offshore Drilling Unit and other marine vessels, although its use is not so limited. The hood may comprise a basic cube shape, which affords a smaller projected footprint than conventional round- or mushroom-shaped hoods and may incorporate an internal flow shaper, such as an inlet/outlet bell, to reduce airflow resistance. In addition, the hood may be configured to incorporate an internal valve or baffle to create a watertight closure.
US07708623B2
A grinding method and to a cylindrical grinding machine grinds metal rod that is pushed through a chuck of a workpiece spindle head. Two backrest seats are ground on and two backrests are then seated. The support of an end area enables a front cone to be ground. A grinding wheel comprised of two different individual wheels serves to grind the front cone and is advanced toward the round rod in the X-direction. The front cone is lodged in a hollow punch at a front end of a quill by displacement of the quill. The desired cylindrical grinding a final contour of the end area is done. Working the rod is done with a single chucking and the end area is cut off from the round rod by one of the individual wheels.
US07708621B2
This polishing apparatus includes a head that holds a semiconductor wafer, a polishing pad that polishes a surface to be polished of the semiconductor wafer held by the head, and a dresser that reconditions the polishing pad by cutting the polishing pad. The polishing apparatus polishes a surface to be polished of the semiconductor wafer while causing the head and the polishing pad to rotate and reconditions the polishing pad by use of the dresser before and after polishing the surface to be polished. The polishing apparatus of the present invention supports at least two dressers so that the dressers can rotate on their own axes and further includes a dresser oscillator that causes the dressers to oscillate simultaneously on the polishing pad.
US07708617B2
A pair of brassiere wings having ends meeting on a longitudinal centerline are interconnected by a closure having a flexible first patch fixed to on of the wing ends and provided with a plurality of fastener members and a flexible second patch fixed to the other of the wing ends and provided with a fastener member engageable with the members of the first patch. A stiff bar extending transversely of the centerline is fixed to the second patch and concave toward a wearer of a brassiere having the wings. One of the patches is of a shape that is longest parallel to the centerline than transversely offset therefrom so that it reduces longitudinal elastic deformation of the respective wing end at the centerline more than offset therefrom.
US07708616B2
A balloon is connected to a cylindrical tube, and the resulting assembly is mounted on a container to serve as a decorative balloon display system.
US07708614B2
An adhesive is applied in a shape having a straight line portion and protruding portions protruding in the direction crossing the straight line portion to the surface of one of a first substrate where organic electroluminescence elements have been formed and a second substrate for sealing the organic electroluminescence elements, and the first and second substrates are pressed together in such a manner that the first and second substrates face and approach each other, and thereby, the adhesive is spread between the first and second substrates so that the organic electroluminescence elements are sealed.
US07708611B2
A sea survival device (1) comprising a container (2) with several shells (3, 4) enclosing respective pneumatic liferafts (5, 6) in the deflated and folded-up state, and inflation means; one half-shell (4) enclosing a liferaft (6) is closed by a closure partition (7); the automatically triggered inflation means are operationally associated with at least the first liferaft (5) in a manner such that said first liferaft (5) is inflated first when the survival device (1) is deployed operationally; and the liferaft (6) is operationally associated with inflation trigger means suitable for trigging inflation thereof only once the first liferaft (5) is inflated.
US07708605B2
A base wall (21) of a connector housing (20) is formed with through holes (25), into which terminal fittings (60) are insertable. The inner surface of each through hole (25) includes an inclined portion (26) narrowed toward the rear side from the front surface of the base wall (21) and arranged at a position corresponding to projections (71) for guiding the terminal fitting (60), a straight portion (28) located behind the inclined portion (26), extending in an inserting direction toward the rear surface of the base wall (21) and having a press-in area for press-in portions (67), and restricting portions (27) defining steps together with the straight portion (28), extending from a taper end of the inclined portion (26) to the steps (35) and tightly holding rear parts of the projections (71) while preventing loose movements.
US07708601B2
A connector reduced in depth dimension. Contact portions of first and second signal contacts and ground contacts for high-speed transmission are arranged in a housing in a row in a contact arranging direction orthogonal to a fitting/removing direction, and contact portions of contacts for non-high-speed transmission are arranged in the housing in a row in the contact arranging direction below the contact portions of the first and second signal contacts and the ground contacts. Terminal portions of the first and second signal contacts and the ground contacts are arranged in a row in the contact arranging direction, and press-fitting portions of the contracts for non-high-speed transmission are press-fitted in the housing along the direction of height of the housing, whereby they are disposed between the contacts portions and the terminal portions of the first and second signal contacts and the ground contacts.
US07708600B2
An electrical connector (100) in accordance with the present invention is capable of mating with at least one of the first and second complementary connectors. The electrical connector includes a housing (2), a number of first terminals (41) and a pair of second terminals (42). The housing includes an upper wall (21), a lower wall (22) opposite to the upper wall, and a pair of sidewalls (23) connecting with the upper and lower walls. The housing defines a receiving space (20) circumscribed by the upper wall, the lower wall and the sidewalls. The first terminals are assembled to the upper wall, and the second terminals are assembled to corresponding side walls. Each terminal includes a mating portion (40), an intermediate portion (43) engaging with the housing to retain the terminals in the housing and a tail portion (44). The mating portions of the first terminals are exposed to the receiving space and the mating portions of the second terminal are laterally exposed outside the housing.
US07708583B2
An electrical connector assembly includes an electrical connector and a heat dissipate device disposed upon the electrical connector. The heat dissipate device includes a heat plate, a heat pipe secured on the heat plate and a load plate located between the heat plate and the heat pipe. The load plate has retention sections engaging with the heat plate for positioning the heat plate on the load plate in three directions.
US07708582B2
The electric connector comprises a first plug-in or receiving part (2) and a second plug-in or male plug (3) which are electrically connectable by relatively translating the plugging parts (2, 3) along a connection axis (X) and is characterised in that said first plug-in part (2) is provided with first guiding means (16, 26) interacting with the second guiding means of the connection element (43) of the second plug-in part (3) in such a way that the connection element is enabled to be displaceable with respect to the first plug-in part, and said second plug-in part (3) comprises a box (33) provided with third guiding means interacting with said connection element (43) in such a way that the connection element is enabled to be displaceable with respect to the box along the connection axis (X) and elastic means generating the movement of the connection element with respect to the box.
US07708577B2
The invention relates to an electrical connection structure for a superconductor element cooled by a cryogenic fluid and connected to an electrical bushing, which bushing passes successively through an enclosure at an intermediate temperature between ambient temperature and the temperature of the cryogenic fluid, and an enclosure at ambient temperature, said bushing projecting outside the ambient temperature enclosure. According to the invention, said intermediate enclosure is filled at least in part with a solid material of low thermal conductivity, such as a polyurethane foam or a cellular glass foam. The invention is applicable to connecting a superconductor cable at cryogenic temperature to a device for equipment at ambient temperature.
US07708576B2
A high-voltage electrical connector system comprises a bushing with a longitudinal axis, a shoulder, a first end, and a second end, wherein the shoulder is between the first end and the second end; a ring arranged circumferentially around a first outside diameter of the bushing, the ring disposed between the shoulder and the second end, the ring including a channel therein defining a circumferential extension extending axially toward the first end; a ground shield disposed on a second outside diameter of the bushing between the ring and the second end, the ground shield comprising one or more of conductive material and semiconductive material; and an insulative portion adjacent the ring and disposed circumferentially over a portion of the ground shield.
US07708571B2
A socket assembly (1) in accordance with a preferred embodiment of the present invention comprises a socket body (20) holding a plurality of contacts therein, a pick up cap (22) fixed onto the socket body, and a loading plate (3) capable of moving between a closed position and a open position with regard to the socket body (20). A locking device (5) is proved to lock the loading plate (3) to a closed position. The pick up cap (22) comprises a flat suction surface (220) and at least one latch (222) for latching the loading plate (3) so that the pick up cap (22) can be attached to the loading plate (3) when the loading plate (3) is in a closed position, and detached from the socket body (20) when the loading plate (3) moves away from the socket body to an open position.
US07708570B2
In one embodiment of the present invention, a universal serial bus (USB) flash drive rotary device is disclosed to include a plastic frame including a USB flash drive and a USB plug connector and a rotary tube at least partially enclosing said plastic frame for deploying said USB plug connector, the USB flash drive is coupled to the USB plug connector, the rotary tube is turned to retract said USB plug connector, the USB flash drive rotary device is for deploying the USB plug connector to couple the USB flash drive to a USB port.
US07708567B2
A connector which is capable of preventing crosstalk from occurring when a plurality of pairs of differential signal transmission contacts are arranged in a horizontal row. A housing holds a plurality of connector modules with a gap between adjacent ones thereof. Each connector module is comprised of a plate-shaped holding member, a plurality of first signal contacts held on one surface of the holding member, and a plurality of second signal contacts held on the other surface of the holding member. Positions of the respective first signal contacts of the plurality of connector modules, and positions of associated ones of the second signal contacts of the connector modules are made approximately coincident with each other in the direction of the height of the housing, respectively.
US07708564B2
A circuit board and connector for use in an electrical connector has been provided. The circuit board comprises first and second signal contacts associated as a differential pair. A ground contact is located immediately adjacent the first signal contact and is joined directly to a ground plane provided within the circuit board. A floated contact is located immediately adjacent the second signal contact. A component interconnects the floated contact to the ground plane, forming an open circuit when a DC signal is impressed on the floated contact and a closed circuit when AC interference is impressed on the floated contact.
US07708563B2
A connector housing includes a housing and a shield. The housing has an interior chamber extending between housing mating and back ends. The inner surface has loading and transition portions, with the loading portion located proximate to the housing mating end and the transition portion located proximate to the housing back end. The shield is shaped to fit in the interior chamber and extends between a shield mating end and a shield back end. The shield back end includes a ground contact opening. The shield includes a rim protruding from the shield back end that extends around a portion of an outer periphery of the shield back end. The rim includes a plurality of rim ends separated by a gap. The rim engages the transition portion to prevent the shield being removed through the housing mating end and the gap exposes a portion of the transition portion.
US07708557B2
A dental prosthesis for periodontal integration is disclosed. Furthermore a customized dental prosthesis for osseointegration is disclosed having a first manufactured portion shaped to substantially conform to the three-dimensional surface of a root of a tooth to be replaced and a second manufactured portion shaped to substantially conform to the three-dimensional surface of a crown of a tooth to be replaced. Furthermore a customized manufactured splint is disclosed to position and fixate a tooth-shaped prosthesis. Furthermore a CAD/CAM based method of and a system for manufacturing a customized dental prosthesis replacing an extracted tooth is disclosed, where the extracted tooth is scanned regarding its three-dimensional shape and substantially copied using (a) an imaging system in-vitro like a 3D scanner or in-vivo like a cone beam CT system, (b) CNC machinery and (c) biocompatible material that is suitable to be integrated into the extraction socket and at least partially adopted by the existing tissue forming the socket.
US07708551B2
A hot runner system having a melt distribution system that is reusable and reconfigurable to vary drop or nozzle locations to meet various design requirements. The melt distribution system includes a melt distributor in fluid communication with a melt source, at least one melt conduit in fluid communication with the melt distributor, and at least one nozzle in fluid communication with the at least one melt conduit. The hot runner system also includes a backing plate; a manifold plate detachably connected to the backing plate; a melt distribution system positioned between the backing plate and the manifold plate and having at least one nozzle associated therewith. The hot runner system may be configured and reconfigured to accommodate various drop or nozzle locations.
US07708548B2
Embodiments of stents having profiles that improve gripping of the stent on a stent delivery system are provided. Additionally, embodiments of molds for fabricating the stents are provided.
US07708541B2
A method and apparatus for continuously producing preselected lengths of coiled tubing are disclosed. According to the method, plastic tubing is continuously wound onto a rotating main tube shaft (24). Downstream from the point where the tubing begins to wind about the shaft, a heat source (46) is directed toward the coiled tubing, softening it as it traverses thereby. Further downstream, a cool-air source (48) directed at the softened tubing sets the tubing into its coiled form. Subsequently, the coiled tubing is cut into preselected lengths by a cutter (50) downstream from the cool-air source.
US07708539B2
A device is suggested for calibrating an extruded plastic profile (1) having a shaping extrusion die (3) and having a framework (6) which is displaceable in the longitudinal direction of the plastic profile (1) in relation to the extrusion die (3), which has a cooling tank (5) and, between the cooling tank (5) and the extrusion die (3), a dry calibration apparatus (4) which is replaceably attached to a carrier (12) and is connectable on one hand to supply lines for a coolant liquid feed and removal and on the other hand to a partial vacuum. To obtain advantageous mounting conditions, it is suggested that the carrier (12), which is adjustable in relation to the cooling tank (5) in the longitudinal direction of the plastic profile (1), form a distributor, connected to the supply lines (16, 17), having line transitions (25) for the coolant liquid and the partial vacuum in the placement area of the dry calibration apparatus (4), which is provided with corresponding line transitions.
US07708535B2
Systems and methods for providing a dynamically adjustable, synchronously and/or asynchronously reciprocating fluid dispenser. A pump drive motor is coupled to the reciprocating fluid pump to actuate a pump shaft within a pump cylinder, wherein the pump shaft includes a duct that allows fluid to selectively pass thereby within the pump cylinder. As the pump shaft rotates within the pump cylinder, fluid is allowed to enter into a pump bore defined by a portion of the pump cylinder through a pump ingress port. As the pump shaft rotates, it blocks the pump ingress port. Further rotation allows the duct to allow the fluid in the pump bore to be dispensed through a pump egress port. An adjustment motor is coupled to an adjustment mechanism, which selectively adjusts the volume of the pump bore. A controller is coupled to the adjustment motor to dynamically control the adjustment motor, to cause the adjustment mechanism to be precisely and repeatably modified, and/or to control the particular waveform. As such, the volume of fluid dispensed is extremely accurate, repeatable, and dynamic.
US07708528B2
Gas turbine engine components having an airfoil extending outwardly of a platform are mounted in adjacent relationship, and such that cooling air flows outwardly of a gap between mating faces of the platforms. The location of localized hot spots is identified on the platform, and the mating faces are designed to provide cooling air through the gap to address these hot spots. A suction side edge of the platform has a curved portion extending inwardly into the platform, and the pressure side has a curved portion bulging outwardly away from the airfoil. When these two portions on adjacent components mate, a gap is provided between two platforms that provides leakage cooling air to the hot spot.
US07708527B2
An emergency power system may provide hydraulic and electrical power to an aircraft in the event of a failure of the aircraft's primary control power system. The system may be constructed as a ram air turbine in which a single ram air fan may drive both a hydraulic pump and an electrical generator. A unique gearbox may incorporate compound gearing to permit the pump and the generator to be driven at different speeds. Thus the pump and the generator may be driven at their respective optimum speeds. The pump and the generator may be detachably mounted on a gearbox that supports the ram air fan. The detachable mounting of the pump and generator may accommodate ease of maintenance of these items. The gearbox may be provided with a ground testing port through which rotational testing force may be introduced to a shaft that supports the ram air fan. This may permit ground level testing of the system. Ground level testing may reduce a need to perform periodic in-flight testing of the system.
US07708526B2
A propeller assembly is provided for mounting on a rotatable propeller shaft of a watercraft. The propeller assembly includes a housing structure extending along a longitudinal axis. The housing structure includes an outer surface and an inner surface defining a cavity having a polygonal-shaped cross-section defined by at least one corner and at least one sidewall. A bushing assembly is receivable in the cavity of the housing structure. The bushing assembly includes a spindle having an inner surface defining a passageway for receiving the propeller shaft therethrough and an outer surface having a plurality of circumferentially spaced fin pairs extending therealong. Each fin pair includes a first fin extending from the outer surface of the spindle and a second fin extending from the outer surface of the spindle at a predetermined angle to the first fin. The bushing assembly also includes a bushing positioned between the spindle and the inner surface of the housing structure.
US07708524B2
A method and system for detecting asymmetric utilizing lateral tower acceleration data may include: providing a lateral tower acceleration monitoring system; determining from the lateral tower acceleration monitoring system whether a lateral tower acceleration is above an acceleration limit; determining whether a rotor-mass imbalance condition exists; and determining whether the lateral tower acceleration coincides with icing on a rotor.
US07708518B2
A system and method for actively managing blade tip clearances in a turbine engine, particularly under steady state operating conditions such as at base load, involves routing a portion of air from a rotor cooling air circuit to a vane carrier or other stationary support structure surrounding the turbine blades. Because the temperature of the air is less than the temperature of the stationary support structure, the stationary support structure will thermally contract when the air is passed in heat exchanging relation therewith. In one embodiment, the air can be passed through one or more passages extending through at least a portion of the stationary support structure. The contraction of the stationary support structure reduces the blade tip clearance because the blades do not contract. Thus, fluid leakage through the clearances is minimized, which in turn can increase engine performance.
US07708514B2
A system and method for automated handling, transferring and storing conventional cargo storage containers on a cargo ship wherein the containers are stored in a multi-tier cell system and are manipulated by powered transfer units which are selectively moveable along an intersecting overhead track system such that containers may be simultaneously retrieved from, moved or placed within any of the cells of the ship. The transfer units are equipped both with hoists, which control spreader beams which are selectively secured to the cargo containers, and guide stabilizers, which prevent undesirable movement of the cargo containers when they are elevated above the cell structures such that the containers may be manipulated even during rough sea conditions such that the system is essentially continuously operable as a floating supply distribution system.
US07708507B2
A locking mechanism to secure a wheelchair while transporting in a vehicle comprises a base with a guide channel adapted to accept a catch pin and has been secured to a wheelchair. The catch pin is guided into the channel by an angled portion of the base. A locking mechanism cooperates with a pivot plate to secure the catch pin within the guide channel. A release mechanism allows disengagement. The guide channel includes a deformation groove that allows the mechanism to operate even when the metal has been deformed through repeated use. Lips are also provided at critical locations to allow free rotation of the parts even when the metal is deformed due to use.
US07708505B2
A power tool for drilling a hole in a workpiece made of wood or a wood material. The power tool generally includes a tool housing defining a handle and a motor contained within the tool housing that includes an output shaft that spins about a motor axis. A gear housing is connected to the tool housing. An output spindle is supported for rotation about a spindle axis in the gear housing. The spindle axis is disposed about ninety degrees from the motor axis. A gear portion on the output shaft is engaged to a gear portion on the output spindle. The motor and the gear portions are configured to rotate the output spindle at a speed in range from about five thousand revolutions per minute to about twenty-five thousand revolutions per minute. A cutting member is connected to the output spindle. The cutting member includes fluted cutting blades. A carriage assembly includes a base member and a head member connected by a first post having a first compliant member and a second post. The head member slides relative to the first and second posts and against a force exerted by the first compliant member when the head member is moved toward the base member to pass the cutting member through the base member to engage the workpiece. The base member includes a generally planar face on a bottom surface of the base member that is generally perpendicular to the spindle axis.
US07708502B2
A device for stabilizing slopes having a first plate and a second plate attached to the first plate at a non-perpendicular angle. The second plate is configured to inhibit rotation of the first plate. At least one gusset is disposed on a first side of the second plate and attaches the first plate to the second plate. At least one strut is disposed on a second side of the second plate and attaches the first plate to the second plate. A guide tube is non-pivotally attached to the first plate such that at least one of a rod and an extension of the anchor are rotatable within the guide tube. The guide tube is a hollow cylinder that is completely closed except at the ends thereof.
US07708495B1
A levee apparatus is constructed of base panels connected end to end and supported by an underlying support such as the earth's surface. Side panels interlock with the base panels and with each other to form a generally triangular transverse cross section and a hollow interior that can be filled with a selected fill material. Interlocking projections on the side panels interlock with apertures of the base and with notches or recesses of other side panels.
US07708494B2
A water diversion system includes a hydraulic chute and a chute screen assembly in the hydraulic chute having a wedge wire screen. The water diversion system also includes at least one collection chamber located below the screen configured to collect filtered diversion water which has passed through the screen. The hydraulic chute includes a base, a crest, a sloped accelerator, and an abrupt drop with an adjustable lip, which forms a hydraulic formation in a downstream pool. The hydraulic chute can also include sloped sidewalls, which constrict the flow of water and form fish passage zones. In addition, the chute screen assembly can include a modular panel configured to facilitate construction, maintenance and replacement of the wedge wire screen.
US07708488B2
A joint unit of a control arm of a wheel suspension in a motor vehicle, with a housing (1) and a pivot (2), which is mounted slidingly in the housing by a spheroidal bearing surface (3). The joint unit has a catching device (4) to avoid complete separation of the housing (1) from the pivot (2). The catching device spans over part of the housing (1) in a contactless manner during normal operation. The catching device (4) has at least one flexible catching band or at least one securing strap (4.1, 4.2) with a recess (4.1.1, 4.2.1), into which protrudes a catching pin (1.1, 1.2) of the housing in a contactless manner during normal operation, or at least two securing straps (4.1 and 4.2).
US07708487B2
A binder spine with a generally rectangular back panel that has a width and a length. The back panel is bounded by generally opposed longitudinal edges. The opposed longitudinal edges are joined through living hinges to adjacent side panels. The binder spine is foldable along the living hinges between an open generally flat configuration and a generally closed configuration. At least one post member is located on one of the side panels, and at least one socket member is located on the other side panel. The socket and post members are aligned with one another and include generally cylindrical mating walls. The post and socket members are spaced apart in the open configuration by a distance. The socket and post members are positioned to retainingly interengage one another in the closed configuration to hold the binder spine in that closed configuration. The socket in the socket member receives the post member in a snap fit. When a system including several of these binder spines with different capacities is provided the dimensions and proportions remain substantially the same except for the post members and the width of the back panel.
US07708485B2
A cleaning implement includes a cleaning head having a cleaning operation surface on a bottom, a holding portion arranged on the side opposite the cleaning head, a pipe for coupling the cleaning head and the holding portion, and a valve opening and closing device provided to the pipe so as to be able to hold a first container for receiving a first fluid or a second container for receiving a second fluid. The holding portion includes a lever coupled to the valve opening and closing device so as to open and close a first valve of the first container or a second valve of the second container. A first ejection nozzle can eject the first fluid forward of the cleaning head, and a second ejection nozzle can eject the second fluid rearward of the cleaning head.
US07708475B2
An electro-optical assembly (EA) is provided in which the transmitter and receiver components are integrated together on a single circuit board, which is encapsulated in a single molded EA package. Integrating the transmitter and receiver components on a single circuit board allows the size and complexity of the EA to be greatly reduced as compared to the traditional TO-can and FOT architectures. A standard semiconductor inline automation system and process may be used to manufacture the EA packages so that they may be mass produced with improved throughput, yield and quality as compared to the method currently used to manufacture and assemble the known EA used in the traditional TO-can and FOT architectures.