US08222659B2
A semiconductor light-emitting device includes (A) a light-emitting portion obtained by laminating in sequence a first compound semiconductor layer, an active layer, and a second compound semiconductor layer; (B) a first electrode electrically connected to the first compound semiconductor layer; (C) a transparent conductive material layer formed on the second compound semiconductor layer; (D) an insulating layer composed of a transparent insulating material and having an opening, the insulating layer being formed on the transparent conductive material layer; and (E) a second electrode that reflects light from the light-emitting portion, the second electrode being formed on the transparent conductive material layer and on the insulating layer in a continuous manner, wherein, assuming that areas of the active layer, the transparent conductive material layer, the insulating layer, and the second electrode are respectively S1, S2, S3, and S4, S1≦S2
US08222651B2
A semiconductor device in which the wiring resistance and parasitic inductance of a semiconductor package configuring a power semiconductor module is reduced. In the semiconductor device, a semiconductor chip with an IGBT formed therein and a diode chip are mounted over the upper surface of a die pad. An emitter pad of the semiconductor chip and an anode pad of the diode chip are coupled with a lead by an Al wire. One end of the lead is located in a higher position than the upper surface of the die pad in order to shorten the length of the Al wire for coupling the emitter pad and the lead.
US08222650B2
Semiconductor structures and devices based thereon include an aluminum nitride single-crystal substrate and at least one layer epitaxially grown thereover. The epitaxial layer may comprise at least one of AlN, GaN, InN, or any binary or tertiary alloy combination thereof, and have an average dislocation density within the semiconductor heterostructure is less than about 106 cm−2.
US08222649B2
A semiconductor device and a method of manufacturing the same, to appropriately determine an impurity concentration distribution of a field relieving region and reduce an ON-resistance. The semiconductor device includes a substrate, a first drift layer, a second drift layer, a first well region, a second well region, a current control region, and a field relieving region. The first well region is disposed continuously from an end portion adjacent to the vicinity of outer peripheral portion of the second drift layer to a portion of the first drift layer below the vicinity of outer peripheral portion. The field relieving region is so disposed in the first drift layer as to be adjacent to the first well region.
US08222637B2
A fused aromatic ring derivative shown by the following formula (1): wherein Ra and Rb are independently a hydrogen atom or a substituent, m and n are independently an integer of 1 to 13, and when m and n are two or more, Ras and Rbs may be independently the same or different, and L1 is a single bond or a substituted or unsubstituted divalent linking group, provided that the fused aromatic ring derivative shown by the formula (1) does not have an anthracene ring.
US08222635B2
An electronic device includes at least a substrate, an area on the substrate which has to be protected against moisture and/or oxygen, at least one contact, and an encapsulation layer system including at least a first inorganic layer. The at least one contact extends from the sealed area to a part of the substrate not sealed by the encapsulation layer system. The contact includes a shunt, which is an interruption bridged by an electrically conductive bridge. The first inorganic layer of the encapsulation system is applied so that it is in direct physical contact with the electrically conductive bridge. The bridge has a structure and shape which can be sealingly covered by the encapsulation layer system and is made from a material through which no moisture and/or oxygen can penetrate.
US08222634B2
The present invention relates to a novel anthracene derivative and an organic electronic device using the same. The organic electronic device according to the present invention shows excellent characteristics in efficiency, driving voltage, and life time.
US08222623B2
The invention provides an apparatus and method for generating quantum-correlated and/or polarization-entangled photon pairs with unequal wavelengths. The photon pairs generated collinearly with respect to the pump light via a nonlinear process in a nonlinear optical medium are collected into a single mode fiber and split using a dichroic device. The wavelengths of photons constituting a pair are selected such that, first, their efficient propagation in the same single mode optical fiber, and second, their efficient splitting with high switching ratio, is possible. A detected rate ˜105-106 pairs/s and >98% quantum interference visibility of polarization entanglement is observed. This source, given its performance, robustness and minimum alignment requirements is ideal for quantum communication schemes, in particular for entanglement-based quantum cryptography.
US08222618B2
An object of the invention is to realize a method and an apparatus for processing and observing a minute sample which can observe a section of a wafer in horizontal to vertical directions with high resolution, high accuracy and high throughput without splitting any wafer which is a sample. In an apparatus of the invention, there are included a focused ion beam optical system and an electron optical system in one vacuum container, and a minute sample containing a desired area of the sample is separated by forming processing with a charged particle beam, and there are included a manipulator for extracting the separated minute sample, and a manipulator controller for driving the manipulator independently of a wafer sample stage.
US08222616B2
A system and method of adapting a radiation therapy treatment plan for a patient by varying the fraction size delivered to the patient on any individual day, based at least partially on the use of daily patient registration (i.e., taking images of the patient before each fraction is delivered to see the position and size of the tumor on that day). The fraction size can be dynamically altered based upon the biology of the tumor.
US08222615B2
Method has laser scanner for pixel-precise imaging of fluorescent samples having fluorescent dyes. The scanner has sample table, laser and first optical system providing laser beam for exciting the samples, scanner head with deflecting element for scanning sample, first lens, second optical system for forwarding emission beams triggered by the laser beam and deflected by first lens and deflecting element to a detector, position encoder emitting position signals indicating location of the scanner head, electronic element for filtering the detector signals with a time constant and an A/D converter for digitizing the filtered detector signals. The filtered detector signals and the position encoder signals are acquired independently, in parallel and continuously by a computer and are related to a common time base, the A/D conversion being carried out often so that each pixel of an image is always assigned more than one data point.
US08222612B2
The present invention relates to a radiation image capturing apparatus, and includes a radiation image information detector for detecting radiation image information of a subject, a casing containing the radiation image information detector, a reading circuit for reading the radiation image information from the radiation image information detector, and a heat release unit for fastening the reading circuit and releasing heat generated by the reading circuit to the casing.
US08222609B2
An image pickup apparatus includes a base that has electric conductivity, at least one image pickup element, and at least one fixing member for fixing the image pickup element to the base. The base has at least one conducting portion on the surface thereof on the side of the fixing member, and the image pickup element has a conducting portion on the surface thereof on the side of the fixing member. The fixing member is formed of peelable resin for separating the image pickup element from the base by applying current. The area of the conducting portion of the base is larger than the area of the fixing region between the fixing member and the base.
US08222604B2
The present invention is directed to a method for non-contact or stand off chemical detection by selectively exciting one or more analytes of interest using an IR source tuned to at least one specific absorption band without significantly decomposing the analyte and determining if the analyte is present by comparing emitted photons with an IR detector signal made before and during or shortly after exciting the analyte. Another embodiment provides a method for non-contact or stand off chemical detection by selectively exciting one or more analytes of interest using an IR source tuned to at least one specific absorption band without significantly decomposing the analyte, wherein the analyte is excited sufficiently to generate a vapor plume, and wherein the plume is examined to detect the presence of the analyte. Additionally, the present invention provides for a system for non-contact or stand off chemical detection.
US08222601B2
A scanning electron microscope capable of modifying the focal position of a condenser lens with high speed and high reproducibility in order that low-magnification images are obtained at large depths of focus and that high-magnification images are obtained at high resolution. The microscope has a specimen-holding portion, an electron beam source, a condenser lens for converging the electron beam, an objective lens for focusing the converged beam into a very small spot onto a specimen, scan coils, a detector for detecting a specimen signal emanating from the specimen, and a display portion for displaying the detected specimen signal as an image. An axisymmetric electrode is disposed within the magnetic field produced by the condenser lens. A voltage is applied to the electrode.
US08222591B2
In accordance with an embodiment, a proximity sensor includes a driver, a photodiode (PD), an analog-to-digital converter (ADC) with analog-to-digital-to-analog (ADA) feedback, and a controller. The driver is adapted to selectively drive a light source. The photodiode (PD) is adapted to produce a photodiode current signal (Idiode) indicative of an intensity of light detected by the PD, where the light detected by the PD can include ambient light and/or light transmitted by the light source that was reflected off an object proximate the PD. The controller is adapted to control the driver and the ADC with ADA feedback. A digital output of the ADC with ADA feedback is indicative of a proximity of an object to the PD with at least a majority of the ambient light detected by the PD rejected.
US08222584B2
A light fixture, using one or more solid state light emitting elements utilizes a diffusely reflect chamber to provide a virtual source of uniform output light, at an aperture or at a downstream optical processing element of the system. Systems disclosed herein also include a detector, which detects electromagnetic energy from the area intended to be illuminated by the system, of a wavelength absent from a spectrum of the combined light system output. A system controller is responsive to the signal from the detector. The controller typically may control one or more aspects of operation of the solid state light emitter(s), such as system ON-OFF state or system output intensity or color. Examples are also discussed that use the detection signal for other purposes, e.g. to capture data that may be carried on electromagnetic energy of the wavelength sensed by the detector.
US08222578B2
A household appliance has a housing and a door that define an interior, and an electric controller. A measuring device is disposed in the interior for measuring a physical parameter and includes a measuring probe and a probe antenna. A lighting device for illuminating the interior of the household appliance includes a cover and a transmit or receive antenna. The transmit or receive antenna is disposed on the housing and sealed from the interior in a substantially airtight manner using the cover. The transmit or receive antenna is in signal communication with the electric controller allowing wireless signal transmission between the measuring probe and the electric controller.
US08222577B2
Method for treating a crank pin of a crank shaft. In the method hardness of the crank pin surface is measured and when the hardness is over a predetermined limit value, depth of the hard spot is measured. Heat treatment parameters are determined at least on the basis of the depth measurement and the hard spot is heat treated. During the heat treatment the hard spot is heated by an induction heating device.
US08222573B2
A dual-spectrum intelligent cooking and baking machine without oil fume includes a housing, a top cover, an inner cylinder with heat preservation, an inner cooking and baking machine and a control circuit. An upper heater is disposed on the inner top surface of the top cover, and a lower heater is disposed on the inner undersurface of the inner cylinder with heat preservation. The upper heater and the lower heater are optical heaters. An insulating layer with light and heat penetration is disposed on the lower heater. The inner cooking and baking machine is a pan, a stockpot or a barbecue net rack. The pan or the stockpot is disposed moveably on the upper surface of the insulating layer with light and heat penetration. The barbecue net rack is disposed moveably over the insulating layer with light and heat penetration and is connected with the motor by the coupling device.
US08222568B2
An electrically heated tool adapted for an anchoring device includes a housing having an opening, a heating head extending forwardly out of the opening, and a movable member disposed movably on the heating head and extending forwardly out of the opening. The movable member has an engagement hole permitting extension of the heating head therethrough, a front annular surface, a loading portion disposed on the front annular surface, and a loading space defined between the loading portion and the front annular surface. The movable member is movable relative to the heating head between an extended position whereat a front pressing surface of the heating head is spaced apart from a forwardly protruding nose of the device, and a retracted position whereat the front pressing surface contacts the nose. A spring is disposed for biasing the movable member toward the extended position.
US08222567B2
A system for laser shock peening includes a laser positioned to direct a laser pulse at a first side of a work piece and a coupler on a second side of the work piece. The system further includes a Doppler shift detector positioned to measure a velocity of the coupler. A method for laser shock peening includes depositing an amount of energy from a laser pulse into a first side of a work piece and transmitting a pulse having a first frequency at a second side of the work piece. The method further includes receiving a reflected pulse having a second frequency from the second side of the work piece and determining the velocity of the work piece based on the difference between the first frequency and the second frequency.
US08222563B2
A beam capturing device for a processing machine includes a housing and at least one rotating body. The housing includes a substantially linear opening for receiving a cutting beam from the processing machine during processing of a workpiece. The at least one rotating body is arranged beneath the opening in the housing. The at least one rotating body is arranged to be rotationally driven about its axis of rotation and is arranged to absorb energy from the cutting beam entering the housing through the opening.
US08222562B2
Mastering tools and systems and methods for forming a plurality of cells on the mastering tools are provided. In particular, the systems vary the geometry of the cells or the placement of the cells, or both, for forming a textured surface on a mastering tool.
US08222560B2
Weld faces of electrodes for resistance spot welding are formed with a suitable area of protrusions and/or intrusions. The size, shape, and elevation or depths of the protrusions or intrusions are determined for the formation of suitable spot welds in and between metal workpieces such as aluminum or steel panels for vehicle bodies. The protrusions or intrusions are also conceived and used to form an image on at least a visible surface of the welded article to produce an attractive appearance on the surface of the welded sheet.
US08222557B2
An electric discharge machining apparatus having a gate signal generator for generating a gate signal, a power source for applying a voltage across a work gap formed between a tool electrode and a workpiece, a gap voltage detector for detecting a gap voltage of the work gap, an electric discharge detector for supplying an electric discharge detection signal representing electric discharge to the gate signal generator. The electric discharge detector includes a counter for generating a sample clock having a frequency greater than the frequency of the gate signal, and a comparator for receiving the gap voltage and determining that a fall in the gap voltage is larger than a specified voltage difference in each sample clock. The electric discharge detection signal is generated in response to an output signal of the comparator.
US08222535B2
A circuit arrangement comprising a set of signal layers, a set of first power layers, a set of second power layers, a set of signal vias, a set of first power vias, a set of second power vias, wherein a signal via of the set of signal vias provides a signal path for a high-frequency (HF) signal current, wherein at least a power via of the set of first power vias and at least a power via of the set of second power vias provide return paths for return currents associated with the signal current, wherein the return path provided by the power via of the set of second power vias is connected with a power layer of the set of second power layers, wherein at least one power layer of the set of first power layers is arranged between the power layer of the set of second power layers and each signal layer of the set of signal layers.
US08222531B2
A board interconnection structure having a first printed wiring board in which a first conductive circuit is arranged on a first insulating layer, the first conductive circuit having, on an end portion thereof, a first connection terminal in which an upper surface width is narrower than a bottom surface width; a second printed wiring board in which a second conductive layer having a second connection terminal is arranged on a second insulating layer; and a connection layer that forms fillets along longitudinal side surfaces of the first connection terminal, and interconnects the first connection terminal and the second connection terminal. The first connection terminal may have a projection portion.
US08222528B2
The invention provides a circuit board structure for electrical testing and a fabrication method thereof. The circuit board structure includes: a core board having a plurality of first circuits, an electroplating conductive wires, and distributing wires for electrical connection thereof; a dielectric layer formed on the core board, the first circuits, the distributing wires and the electroplating conductive wires, wherein the dielectric layer is formed with at least one opening for exposing the distributing wires; a plurality of second circuit formed on the dielectric layer and electrically connected to the first circuits; a solder mask layer formed on the dielectric layer and the second circuits; and at least one first opening formed in the solder mask layer, above the distributing wires, and deep into the dielectric layer to create a broken circuit between the distributing wires and the electroplating conductive wires, thus enabling electrical testing of the circuit board structure, and reducing noise interference.
US08222514B2
A solar energy module includes one or more solar cells, each having a front side for receiving light and an opposite back side. An encapsulant material covers at least the front side of each of the solar cells. The solar energy module also includes a backskin layer formed from a cross-linked mixture of high density polyethylene (HDPE) and acid copolymer bonded to the back side of each of the solar cells.
US08222510B2
The invention provides for a thermoelectric system comprising a substrate comprising a first complex oxide, wherein the substrate is optionally embedded with a second complex oxide. The thermoelectric system can be used for thermoelectric power generation or thermoelectric cooling.
US08222503B2
A sound reverberator device for detachable connection to the strings of a string musical instrument which has strings tensioned over a bridge piece connected to the top wall of the sound box or the instrument. The reverberator comprises three spaced apart metal coil springs secured side-by-side at a common end to a spring support. A metallic string attachment member is secured to a free end of each of the springs. The attachment member has string engaging fingers for engaging a respective one of a pair of adjacent strings of the musical instrument. The attachment member further has a bridge abutment portion for contact with the bridge piece. When the reverberator is connected to the musical instrument, the springs are tensioned with the attachment member connected to the strings whereby vibrations imparted to the strings will be transmitted to the bridge piece and the associated spring. The spring will then vibrate and transmit its vibrations to the sound box through the bridge piece whereby to modify the tonality sound generated by the sound box. A sound damping device also provides progressive sound damping produced by the springs.
US08222502B1
A novel maize variety designated 10216740 and seed, plants and plant parts thereof, produced by crossing Pioneer Hi-Bred International, Inc. proprietary inbred maize varieties. Methods for producing a maize plant that comprises crossing maize variety 10216740 with another maize plant. Methods for producing a maize plant containing in its genetic material one or more traits introgressed into 10216740 through backcross conversion and/or transformation, and to the maize seed, plant and plant part produced thereby. This invention relates to the maize variety 10216740, the seed, the plant produced from the seed, and variants, mutants, and minor modifications of maize variety 10216740. This invention further relates to methods for producing maize varieties derived from maize variety 10216740.
US08222500B1
A novel maize variety designated PHW1W and seed, plants and plant parts thereof. Methods for producing a maize plant that comprise crossing maize variety PHW1W with another maize plant. Methods for producing a maize plant containing in its genetic material one or more traits introgressed into PHW1W through backcross conversion and/or transformation, and to the maize seed, plant and plant part produced thereby. Hybrid maize seed, plant or plant part produced by crossing the variety PHW1W or a trait conversion of PHW1W with another maize variety. Inbred maize varieties derived from maize variety PHW1W, methods for producing other inbred maize varieties derived from maize variety PHW1W and the inbred maize varieties and their parts derived by the use of those methods.
US08222496B2
A novel garden bean cultivar, designated H37113, is disclosed. The invention relates to the seeds of garden bean cultivar H37113, to the plants of garden bean line H37113 and to methods for producing a bean plant by crossing the cultivar H37113 with itself or another bean line. The invention further relates to methods for producing a bean plant containing in its genetic material one or more transgenes and to the transgenic plants produced by that method and to methods for producing other garden bean lines derived from the cultivar H37113.
US08222493B1
A novel soybean variety, designated XBP31005 is provided. Also provided are the seeds of soybean variety XBP31005, cells from soybean variety XBP31005, plants of soybean XBP31005, and plant parts of soybean variety XBP31005. Methods provided include producing a soybean plant by crossing soybean variety XBP31005 with another soybean plant, methods for introgressing a transgenic, mutant trait, and/or native trait into soybean variety XBP31005, methods for producing other soybean varieties or plant parts derived from soybean variety XBP31005. Soybean seed, cells, plants, germplasm, breeding lines, varieties, and plant parts produced by these methods and/or derived from soybean variety XBP31005 are further provided.
US08222474B2
A method for the solvent extraction of 1,3-butadiene from a mixture of C4 hydrocarbons that employs a distillation tower to produce the desired 1,3-butadiene product as an overhead and a separate bottoms stream that is removed from and not recycled in the solvent extraction process.
US08222470B2
A process for oligomerizing an olefinic hydrocarbon feed is described which consists of bringing said feed into contact with a catalyst comprising a silica-alumina, the silica content of said catalyst being in the range 5% to 95% by weight, said catalyst being prepared using a process comprising at least: a) mixing at least one alumina compound which is partially soluble in an acid medium with either at least one silica compound which is completely soluble in the reaction mixture or a combination formed by at least one silica compound and at least one alumina compound, said silica and alumina compounds being completely soluble in the reaction mixture, in order to form a solid precursor of said catalyst; b) hydrothermal treatment of the solid derived from step a) by calcining in moist air for a period in the range 4 to 7 hours.
US08222467B2
A non-extracted hydrocarbon composition feed is substantially free of both C4− hydrocarbons and the C7+ aromatic hydrocarbons and contains benzene and benzene coboilers as well as sulfur, nitrogen, olefins and dienes.
US08222454B2
The present invention discloses a process for preparing optically pure milnacipran and their pharmaceutically acceptable salts, which adopts racemic milnacipran as starting material, tartaric acid derivatives and their compositions as resolving agents to resolve.
US08222450B2
Sulfonic acid anhydrides, and more particularly triflic anhydride, are prepared by reacting a sulfonic acid or a mixture of two sulfonic acids with a reactant exhibiting acid pseudohalide tautomerism and containing at least one carbon atom which is involved in the tautomerism bearing two halogen atom substituents.
US08222445B2
The present invention relates to an industrially usable process for preparing alkali metal and alkaline earth metal tricyanomethanides in particularly high purity.
US08222442B2
A phosphorylcholine group-containing compound that is a structure having a phosphorylcholine group represented by the following formula 1 and an amino group or a group derived from an amino group in an identical compound. (In the formula, m is 2 or more and 6 or less and p is 1 or 2. Each of X1, X2 and X3 is an alkyl group whose carbon number is 1 or more and 6 or less.)
US08222439B2
The invention relates to a process for the production of carboxylic acid esters by esterification of carboxylic acids and/or transesterification of carboxylic acid esters with alcohols in the presence of a liquid metal catalyst, characterized in that the liquid metal catalyst is the alkaline earth metal salt of a carboxylic acid.
US08222437B2
Systems and methods for extracting lipids of varying polarities from oleaginous material.
US08222431B2
The present invention is directed to an improved process for synthesizing phosphonic and phosphinic acid chymase inhibitor compounds.
US08222429B2
The present invention provides a photolabile protecting group that can be removed by light irradiation under mild conditions. More specifically, the present invention provides a method comprising protecting a reactive functional group (e.g., a hydroxyl group, amino group, carboxyl group, carbonyl group, phosphodiester group, etc.) by the photolabile protecting group, and then removing the photolabile protecting group simply by light irradiation under neutral conditions.The present invention relates to a compound represented by Formula (3): wherein Ar1 is an optionally substituted aromatic or heteroaromatic ring, Ar2 is an optionally substituted aryl or heteroaryl group, X is a leaving group, and n is an integer of 1 or 2; and a method of protecting and deprotecting an amino group etc. using the compound.
US08222428B2
The present invention discloses a method for continuously producing an oxidized cyclic phenol sulfide which comprises the continuous steps of reacting a para-alkyl phenol compound as a raw material with 1.7 to 2.5 molar equivalent of sulfur and 0.25 to 0.75 molar equivalent of an alkali metal reagent per 1 mol of the phenol compound (the first step); and oxidizing a cyclic phenol sulfide of the formula (2) produced by the above reaction with an oxidizing agent(s) in the same reactor as that of the first step and without taking the cyclic phenol sulfide out of the reactor: wherein R represents a straight or branched alkyl group having 1 to 6 carbon atoms, and m is an integer from 4 to 8, to obtain an oxidized cyclic phenol sulfide of the formula (3) (the second step): wherein R represents a straight or branched alkyl group having 1 to 6 carbon atoms, m is an integer from 4 to 8, and n is 1 or 2.
US08222426B2
An aromatic compound of the following formula (1), (2), (5) or (6), wherein, Ar1 and Ar3 represent a tetra-valent aromatic hydrocarbon group or a tetra-valent heterocyclic group, and Ar2, Ar4, Ar5, Ar6 and Ar7 represent a tri-valent aromatic hydrocarbon group or a tri-valent heterocyclic group, A1 represents —Z1—, —Z2-Z3— or —Z4═Z5—, wherein Z1, Z2 and Z3 represent O, S or the like and Z4 and Z5 represent N, B, P or the like, X1, X2, X3, X4, X9, X10, X11, and X12 represent a halogen atom or the like.
US08222423B2
In recognition of the need to develop novel therapeutic agents and efficient methods for the synthesis thereof, the present invention provides novel bifunctional, trifunctional, or multifunctional compounds for inhibiting histone deacetylases, and pharmaceutically acceptable salts and derivatives thereof. The present invention further provides methods for treating disorders regulated by histone deacetylase activity (e.g., proliferative diseases, cancer, inflammatory diseases, protozoal infections, hair loss, etc.) comprising administering a therapeutically effective amount of an inventive compound to a subject in need thereof. The present invention also provides methods for preparing compounds of the invention.
US08222421B2
Certain chemical entities chosen from compounds of Formula 1 and pharmaceutically acceptable salts, solvates, chelates, non-covalent complexes, and prodrugs thereof, are provided herein. Pharmaceutical compositions comprising at least one chemical entity and one or more pharmaceutically acceptable vehicles chosen from carriers, adjuvants, and excipients, are also provided herein. Methods of treating patients suffering from certain diseases and disorders responsive to angiogenic kinase modulation, which comprise administering to such patients an amount of at least one chemical entity effective to reduce signs or symptoms of the disease or disorder are disclosed. These diseases include cancer, including breast neoplasia, endometrial cancer, colon cancer, and neck squamous cell carcinoma. Methods of treatment include administering at least one chemical entity as a single active agent or administering such at least one chemical entity in combination with one or more other therapeutic agents. A method for determining the presence or absence of an angiogenic kinase in a sample comprising contacting the sample with at least one chemical entity under conditions that permit detection of activity of the angiogenic kinase, detecting a level of the activity of the angiogenic kinase, and therefrom determining the presence or absence of the angiogenic kinase in the sample.
US08222419B2
The present invention provides a compound, an oxepin derivative having excellent histamine receptor antagonistic action, which is useful as an antihistamine. The oxepin derivative of the present invention has a potent histamine receptor antagonistic action. Further, the compound of the present invention shows low intracerebral migration even when a mouse that is orally administered with the compound is subjected to an intracerebral receptor binding test, so that the compound has preferred properties of alleviating side effects in the central nervous system, such as drowsiness. The oxepin derivative of the present invention is very useful as a novel antihistamine having smaller side effects in the central nervous system, such as drowsiness.
US08222399B2
A photoreactive polysaccharide which comprises a polysaccharide bound to a glycidyl ester via a covalent bond, a photocrosslinked-polysaccharide prepared by using the photoreactive polysaccharide, and medical products comprising the photocrosslinked-polysaccharide.
US08222391B2
Provided are an oligonucleotide primer set for amplifying at least one target sequence of the genomic RNA of norovirus, an oligonucleotide probe or probe set specifically hybridizing with at least one target sequence of the genomic RNA of norovirus, a microarray immobilized with the probe or probe set, and a method of detecting norovirus using the probe or probe set.
US08222390B2
The present invention provides compositions and their use in diagnosing and/or distinguishing inflammatory bowel disease and irritable bowel syndrome.
US08222389B2
The present invention relates to the use in a diagnostic hybridization assay of a molecular beacon probe for lowering: the effect of sequence variations in a nucleic acid analyte, and/or the IBL effect due to the possible opening of the stem-loop structure of a molecular beacon by way of (contaminants in the amplification) enzymes, which assay comprises the steps of contacting a set of primers and a sample containing the nucleic acid analyte to amplify the analyte and detecting the amplified analyte or its complement using a molecular beacon probe, wherein the molecular beacon probe comprises one or more nucleotides and/or nucleotide analogues that have an affinity increasing modification. The invention also relates to such molecular beacon probe and to a kit for performing a diagnostic assay using such molecular beacon probe.
US08222388B2
Regulatory regions suitable for directing expression of a heterologous polynucleotide in plant tissues, e.g., flower and silique tissues, are described, as well as nucleic acid constructs that include these regulatory regions. Also disclosed are transgenic plants that contain such constructs and methods of producing such transgenic plants.
US08222383B2
Disclosed are DNA encoding a polypeptide which can modulate the activity of a muscle-specific tyrosine kinase, and others. The DNA is selected from the following members (a) to (d): (a) DNA comprising a specific nucleotide sequence; (b) DNA comprising a nucleotide sequence capable of hybridizing with a specific nucleotide sequence under stringent conditions; (c) DNA comprising a nucleotide sequence encoding an amino acid sequence having the substitution, deletion and/or addition of one or several amino acid residues in a specific amino acid sequence; and (d) DNA comprising a nucleotide sequence having 90% or higher homology to a specific nucleotide sequence.
US08222371B2
Proteins (INSP141, INSP142, INSP143, and INSP144) identified as anthrax receptor-like proteins containing von Willebrand factor A (vWFA) and Anthrax receptor extracellular (ANT_IG) domains and the use of these proteins and nucleic acid sequences from the encoding genes in the diagnosis, prevention and treatment of disease are described.
US08222365B2
This disclosure relates to a polyamideimide resin containing a structure represented by formula (1):
US08222350B2
A thermoplastic composition comprising in combination a polycarbonate, a polycarbonate-polysiloxane copolymer, an impact modifier composition comprising ABS or BABS, a second impact modifier different from BABS or ABS, an aromatic vinyl copolymer, and optionally a gel-type low gloss additive, wherein the 60° gloss of the thermoplastic composition is measured to be less than or equal to 14 GU on 3 millimeter chips having a textured surface when measured according to ASTM D2457, and wherein a molded sample of the thermoplastic composition has a low temperature notched Izod impact at −40° C. of at least 65 KJ/m2 when measured according to ISO 180/1A is disclosed. The composition has low gloss, high low temperature impact, and a significantly improved balance of properties.
US08222343B2
The present invention is directed to a method for preparing a cellulose reactive adduct of polyvinylamide and a composition resulting from the method. The preparation of the cellulose reactive adduct is carried out close to a Critical Concentration defined herein. When the reaction is run close to this Critical Concentration, the risk of gelation is minimized, consumed glyoxal is maximized, and shelf live is enhanced. Additionally, the glyoxalated vinylamides of the present invention impart improved wet and dry strengthening efficiency to paper and paperboard when compared to adducts disclosed in previously described art.
US08222341B2
Semi-conductive silicone compositions and articles of manufacture containing these compositions are formed by combining a silicone precursor composition with an alkali metal salt and polymerizing the silicone precursor composition in the presence of the alkali metal salt to form a polymerized semi-conductive silicone composition. The polymerized silicone composition can be formed into a solid or foam article of manufacture having a volume resistivity of E8 to E12 ohm-cm, such as a roller or an anti-static belt.
US08222339B2
An adhesive composition comprises: (i) at least one ethylene/α-olefin interpolymer, (ii) at least one tackifier; and (iii) an oil or a low molecular weight polymer. Preferably, the ethylene/α-olefin interpolymer has a Mw/Mn from about 1.7 to about 3.5, at least one melting point, Tm, in degrees Celsius, and a density, d, in grams/cubic centimeter, wherein the numerical values of Tm and d correspond to the relationship: Tm≧858.91−1825.3(d)+1112.8(d)2. The composition can be used in hot melt adhesives, pressure sensitive adhesives, hot melt pressure sensitive adhesives and thermoplastic marking paints.
US08222333B2
Adhesives containing inter-crosslinked polymeric microparticles are described. The polymeric microparticles include an acrylic polymer. The present disclosure also relates to water-based emulsions containing polymeric microparticles and a suitable inter-crosslinking agent as well as methods of making adhesives from such water-based emulsions.
US08222328B2
A method of manufacturing of the present invention is a method of manufacturing a toothed belt (10) having a belt part (13) and a tooth part (14) sticking out of the belt part (13). This method of manufacturing includes a first step of forming a reinforcing-sheet (12) including a fiber sheet and a coating film formed on the fiber sheet by drying the fiber sheet on which an aqueous treatment agent containing a first rubber latex and a first vulcanizing agent is applied, and a second step of reinforcing a surface of the tooth part (14) with the reinforcing-sheet (12) by vulcanizing the first rubber and a second rubber at the same time while adhering a rubber composition, which is a material for the tooth part (14), including the second rubber and a second vulcanizing agent to the reinforcing-sheet (12). The aqueous treatment agent contains the vulcanizing agent in the range of 10 parts by weight to 100 parts by weight for 100 parts by weight of the first rubber.
US08222326B2
The invention provides a water-based ink composition for inkjet recording which contains vinyl polymer particles containing a styrene-acrylic acid copolymer in which the total content of the constitutional units derived from styrene monomer, acrylic acid, and methacrylic acid is 45% by mass or more; and at least one of an azo pigment represented by Formula (1), a tautomer thereof, a salt or hydrate thereof; and a water-based liquid medium, and which is excellent in discharge stability after a long-term storage or after aging at high temperatures: wherein, Q represents a heterocyclic group; W represents an alkoxy group, an amino group etc.; X1 and X2 each independently represent a hydrogen atom, an alkyl group etc.; R1 represents a hydrogen atom or a substituent; R2 represents a heterocyclic group; and n represents an integer of 1 to 4.
US08222324B2
This invention provides a process for producing an epoxy resin composition having core/shell rubber particles (rubber-like polymer particles) dispersed in an epoxy resin, wherein an epoxy resin composition excellent in the dispersed state of rubber-like polymer particles in an epoxy resin with a reduced amount of contaminants is produced easily and efficiently.The epoxy resin composition having rubber-like polymer particles dispersed well in an epoxy resin with less contaminant is obtained by bringing an aqueous latex of rubber-like polymer particles (B) into contact with an organic medium (C) showing partial solubility in water, then bringing an organic medium (D) having lower partial solubility in water than that of the organic medium (C) into contact therewith to separate water substantially, to remove the rubber-like polymer particles as a dispersion (F) having the polymer particles dispersed in the organic medium, and mixing it with an epoxy resin (A), followed by distilling volatile components away.
US08222310B2
An extruded polypropylene type resin foam having a high expansion ratio of at least 15 times and a closed cell ratio of at least 70% and excellent in the heat insulation property, and its production process, are provided.An extruded polypropylene type resin foam, which is produced by extrusion-foaming a polypropylene type resin composition containing a linear polypropylene type resin having a melt tension at 230° C. of from 5 to 30 g, by using a blowing agent containing at least a hydrocarbon type gas, and which has an expansion ratio of at least 15 times and a closed cell ratio of at least 70%.
US08222308B2
A method of preparing a porous polymer structure comprising the steps of: forming a liquid composition comprising at least one polymer dissolved in at least one solvent; subjecting the liquid composition to stress, and if necessary also to a reduction in temperature, to cause the liquid composition to form a bi-continuous phase separated composition, the bi-continuous phase separated composition comprising a polymer rich phase and a polymer poor phase; solidifying the at least one polymer in the polymer rich phase; and removing the polymer poor phase from the polymer rich phase to provide the porous polymer structure having a bi-continuous morphology from the polymer rich phase.
US08222304B2
The invention relates to process for the treatment of a hydrophobic surface by a liquid film comprising an aqueous phase comprising the coating of said surface by the liquid whose aqueous phase comprises an effective amount of surface properties modifying agent and an active agent.
US08222301B2
The object of the present invention is to provide a method for producing a resin microparticle aqueous dispersion, which can produce monodisperse resin microparticles, does not cause clogging by a product, does not require a high pressure, and has a high productivity. Thus, provided is a method for producing a resin microparticle aqueous dispersion, wherein a fluid having at least one kind of resin dissolved in a solvent with which a resin is soluble and compatible and a fluid of an aqueous solvent join together in a thin film fluid formed between processing surfaces arranged opposite so as to be able to approach to and separate from each other, at least one of which rotates relative to the other, whereby resin microparticles are obtained in the thin film fluid by way of separation/emulsification.
US08222300B2
The present invention provides methods of using halogenated volatile compounds, e.g., halogenated ether, for treating a neurological disorder, e.g., Parkinson's disease.
US08222298B2
Compounds, methods, uses, compositions, kits and packages for the treatment of imbalance between bone resorption and bone formation, based on uses of 4-phenyl-2-propionamidotetralin (4-P-PDOT) and analogs, derivatives, prodrugs, precursors thereof, and salts thereof, are described.
US08222296B2
Conjugates of a gamma-aminobutyric acid (GABA) compound or a glycine compound and an analgesic drug are disclosed. Further disclosed are pharmaceutical compositions containing these conjugates and uses thereof in the treatment of CNS-associated diseases or disorders, optionally in combination with a psychotropic drug.
US08222256B2
The invention provides methods of treating cancer with a compound which inhibits kinases, more specifically IGF1R and Abl, in combination with treatments(s) selected from surgery, radiation, monoclonal antibody, bone marrow or peripheral blood stem cell transplantation, and one or more chemotherapeutic agent(s).
US08222238B2
The present invention relates to the use of pteridine derivatives for the treatment of increased intracranial pressure, secondary ischemia, and disorders associated with an increased level of cytotoxic reactive oxygen species.
US08222237B2
Described herein are 3-(6,6-ethylene-17β-hydroxy-3-oxo-17α-pregna-4-ene-17α-yl)propionic acid γ-lactone derivatives having progestational and aldosterone antagonistic activity. Also described herein are methods of preparing and using these novel compounds.
US08222236B2
This invention discloses 2-methylene-(20E)-20(22)-dehydro-19-nor-vitamin D analogs, and specifically 2-methylene-(20E)-20(22)-dehydro-19-nor-1α,25-dihydroxyvitamin D3, and pharmaceutical uses therefore. This compound exhibits relatively high transcription activity as well as pronounced activity in arresting the proliferation of undifferentiated cells and inducing their differentiation to the monocyte thus evidencing use as an anti-cancer agent and for the treatment of skin diseases such as psoriasis as well as skin conditions such as wrinkles, slack skin, dry skin and insufficient sebum secretion. This compound also shows lower activity in vivo on bone calcium mobilization and similar in vivo intestinal calcium transport activity compared to the native hormone 1α,25-dihydroxyvitamin D3, and therefore may be used to treat autoimmune disorders or inflammatory diseases in humans as well as renal osteodystrophy. This compound may also be used for the treatment or prevention of obesity.
US08222234B1
A method of producing a granule containing at least 40 weight percent phosphoroamidothioate, preferably acephate, by processing the phosphoroamidothioate in powder form along with a liquid through a vertical continuous noncompressive agglomerator having a vertical rotating shaft on which are mounted a plurality of adjustable blades.
US08222219B2
A compound of the formula: wherein Ring A and Ring B are: (1) Ring A is an optionally substituted unsaturated monocyclic heterocyclic ring, and Ring B is an optionally substituted unsaturated monocyclic heterocyclic ring, an optionally substituted unsaturated fused heterobicyclic ring, or an optionally substituted benzene ring, (2) Ring A is an optionally substituted benzene ring, and Ring B is an optionally substituted unsaturated monocyclic heterocyclic ring or an optionally substituted unsaturated fused heterobicyclic ring, or (3) Ring A is an optionally substituted unsaturated fused heterobicyclic ring, and Ring B are independently an optionally substituted unsaturated monocyclic heterocyclic ring, an optionally substituted unsaturated fused heterobicyclic ring, or an optionally substituted benzene ring; X is a carbon atom or a nitrogen atom; Y is —(CH2)n— (n is 1 or 2); or a pharmaceutically acceptable salt thereof, or a prodrug thereof.
US08222214B2
The invention features methods to induce and maintain a protective cytotoxic T-lymphocyte response to a peptide of the HER2/neu oncogene, E75, with the effect of inducing and maintaining protective or therapeutic immunity against breast cancer in a patient in clinical remission. The methods comprise administering to the patient an effective amount of a vaccine composition comprising a pharmaceutically acceptable carrier, an adjuvant such as recombinant human GM-CSF, and the E75 peptide at an optimized dose and schedule. The methods further comprise administering an annual or semi-annual booster vaccine dose due to declining E75-specific T cell immunity. The invention also features vaccine compositions for use in the methods.
US08222211B2
A novel class of embryo derived peptides are described (Preimplantation factor) that were generated synthetically and were tested on peripheral blood immune cells and shown to block activated but not basal immunity, inhibiting cell proliferation and creating a TH2 type cytokine bias. In addition PIF peptides enhance endometrial receptivity by increasing adhesion molecules expression. PIF biological activity appears to be exerted by specific binding to inducible receptors present on the several white cell lineages. PIF peptides, which are immune modulators, therefore may have diagnostic and non toxic therapeutic applications in improving fertility, reducing pregnancy loss as well may be useful when administered for the treatment of autoimmune diseases and for prevention xenotransplants rejection.
US08222209B2
Provided are modified growth hormone polypeptides, nucleic acid molecules encoding modified growth hormone polypeptides and methods of generating modified growth hormone polypeptides. Also provided are methods of treatment using modified growth hormone polypeptides.
US08222196B2
The invention is a composition and method for removing soils containing polymerized non-trans fats from surfaces. The composition comprises a polymer and sequentrant, wherein the polymer is oleophobic and hydrophilic. Optionally, the composition may also include a wetting agent. The composition may be used by applying it to a clean surface as a pretreatment so that when said surface is soiled or contaminated with polymerized non-trans fats it may be easily removed with water.
US08222193B2
The present invention relates to hydrogel particles containing bubbles and having a specific gravity of 0.7 to 1.00 and an average particle diameter of 50 to 500 μm, as well as a process for producing the same. The hydrogel particles may also contain hollow inorganic particles.
US08222183B2
The present invention provides a thermochromic coloring color-memory composition which effectively produce a characteristic that colors can be reversibly memorized and maintained and has applicability to various fields and a thermochromic coloring color-memory microcapsule pigment containing the composition.A thermochromic coloring color-memory composition comprising a homogeneous solubilized mixture of (A) an electron donative coloring organic compound, (B) an electron accepting compound and (C) a compound represented by the following formula (1) as a reaction medium which controls color reactions of the components (A) and (B): wherein X represents any of a hydrogen atom, an alkyl group having 1 to 4 carbon atoms, a methoxy group, and a halogen atom, m represents an integer of from 1 to 3, and n represents an integer of from 1 to 20.
US08222175B2
This invention relates to a process for the preparation of an olefin polymerization catalyst, to the use of the catalyst in olefin polymerization and to the catalyst and polymers obtained. In particular, the invention relates to the preparation of a catalyst comprising an organometallic compound of a transition metal of Group 3 to 10 of the Periodic Table (IUPAC) by a semi-continuous or continuous process.
US08222170B2
Disclosed are a glass substrate for an information recording medium, having excellent scratch resistance and a light weight and having high fracture toughness, the glass substrate having a fragility index value, measured in water, of 12 μm−1/2 or less or having a fragility index value, measured in an atmosphere having a dew point of −5° C. or lower, of 7 μm−1/2 or less, or the glass substrate comprising, by mol %, 40 to 75% of SiO2, 2 to 45% of B2O3 and/or Al2O3 and 0 to 40% of R′2O in which R′ is at least one member selected from the group consisting of Li, Na and K), wherein the total content of SiO2, B2O3, Al2O3 and R′2O is at least 90 mol %, and a magnetic information recording medium comprising a magnetic recording layer formed on the glass substrate.
US08222151B2
A method of lithography patterning includes forming a hard mask layer on a material layer and forming a capping layer on the hard mask layer. The capping layer does not react with oxygen gas during a photoresist ashing process. The capping layer is patterned by using a first resist pattern and a second resist pattern as etch masks. After the capping layer is patterned, the hard mask layer is patterned by using the patterned capping layer as an etch mask.
US08222135B2
By forming an aluminum nitride layer by a self-limiting process sequence, the interface characteristics of a copper-based metallization layer may be significantly enhanced while nevertheless maintaining the overall permittivity of the layer stack at a lower level.
US08222132B2
The present disclosure provides a method that includes forming first and second gate structures over first and second regions, respectively, removing a first dummy gate and first dummy dielectric from the first gate structure thereby forming a first trench and removing a second dummy gate and second dummy dielectric from the second gate structure thereby forming a second trench, forming a gate layer to partially fill the first and second trenches, forming a material layer to fill the remainder of the first and second trenches, removing a portion of the material layer such that a remaining portion of the material layer protects a first portion of the gate layer located at a bottom portion of the first and second trenches, removing a second portion of the gate layer, removing the remaining portion of the material layer from the first and second trenches.
US08222124B2
This method for manufacturing a SIMOX wafer includes: forming a mask layer on one surface side of a silicon single crystal wafer, which has an opening on a region where a BOX layer is to be formed; implanting oxygen ions through the opening of the mask layer into the silicon single crystal wafer to a predetermined depth, and locally forming an oxygen implantation region; annealing the silicon single crystal wafer with the mask layer, and oxidizing the oxygen implantation region so as to form the BOX layer; and removing a coated oxide film that covers the whole silicon single crystal wafer which is formed in the annealing of the silicon single crystal wafer, wherein the mask layer has a lamination comprising an oxide film and either one or both of a polysilicon film and an amorphous silicon film.
US08222118B2
A method of relieving stress in a semiconductor wafer and providing a wafer backside surface finish capable of hiding cosmetic imperfections. Embodiments of the invention include creating a wafer backside surface which can be used for all dies on the semiconductor wafer intended for different product applications and be deposited with backside metallization (BSM) material. The method provides a rough texture on the wafer backside followed by isotropic etching of the wafer backside to recover the wafer strength as well as to preserve the rough texture of the wafer backside. After wafer backside metallization, the rough texture of the wafer backside hides cosmetic imperfections introduced by subsequent processes.
US08222117B2
An SOI substrate and a manufacturing method of the SOI substrate, by which enlargement of the substrate is possible and its productivity can be increased, are provided. A step (A) of cutting a single crystal silicon substrate to form a single crystal silicon substrate which is n (n is an optional positive integer, n≧1) times as large as a size of one shot of an exposure apparatus; a step (B) of forming an insulating layer on one surface of the single crystal silicon substrate, and forming an embrittlement layer in the single crystal substrate; and a step (C) of bonding a substrate having an insulating surface and the single crystal silicon substrate with the insulating layer therebetween, and conducting heat treatment to separate the single crystal silicon substrate along the embrittlement layer, and forming a single crystal silicon thin film on the substrate having an insulating surface are conducted.
US08222113B2
A method for forming a metal-oxide-semiconductor (MOS) device includes at least steps of forming a pair of trenches in a substrate at both sides of a gate structure, filling the trenches with a silicon germanium layer by a selective epitaxy growth process, forming a cap layer on the silicon germanium layer by a selective growth process, and forming a pair of source/drain regions by performing an ion implantation process. Hence, the undesirable effects caused by ion implantation can be mitigated.
US08222103B1
Generally, the subject matter disclosed herein relates to a semiconductor device with embedded low-k metallization. A method is disclosed that includes forming a plurality of copper metallization layers that are coupled to a plurality of logic devices in a logic area of a semiconductor device and, after forming the plurality of copper metallization layers, forming a plurality of capacitors in a memory array of the semiconductor device. The capacitors are formed using a non-low-k dielectric material (k value greater than 3), while the copper metallization layers are formed in layers of low-k dielectric material (k value less than 3). A semiconductor device is also disclosed which includes a plurality of logic devices, a memory array comprising a plurality of capacitors, a conductive contact plate coupled to the plurality of capacitors, and a plurality of copper metallization layers coupled to the logic devices, wherein the plurality of copper metallization layers are positioned at a level that is below a level of a bottom surface of the contact plate. A material other than a low-k dielectric material is positioned between the plurality of capacitors in the memory array.
US08222086B2
A plurality of FPGA dice is disposed upon a semiconductor substrate. In order both to connect thousands of signal interconnect lines between the plurality of FPGA dice and to supply the immense power required, it is desired that the substrate construction include two different portions, each manufactured using incompatible processes. The first portion is a signal interconnect structure containing a thin conductor layers portion characterized as having a plurality of thin, fine-pitch conductors. The second portion is a power connection structure that includes thick conductors and vertical through-holes. The through-holes contain conductive material and supply power to the FPGA dice from power bus bars located at the other side of the semiconductor substrate. The portions are joined at the wafer level by polishing the wafer surfaces within a few atoms of flatness and subsequent cleaning. The portions are then fusion bonded together or combined using an adhesive material.
US08222085B2
Flip chip ball grid array semiconductor devices and methods for fabricating the same. In one example, a near chip scale method of semiconductor die packaging may comprise adhering the die to a substrate in a flip chip configuration, coating the die with a first polymer layer, selectively removing the first polymer layer to provide at least one opening to expose a portion of the die, and depositing a first metal layer over the first polymer layer, the first metal layer at least partially filling the at least one opening to provide an electrical contact to the die, and including a portion that substantially surrounds the die in a plane of an upper surface of the first metal layer to provide an electromagnetic shield around the die.
US08222078B2
A semiconductor device package die and method of manufacture are disclosed. The device package die may comprise a device substrate having one or more front electrodes located on a front surface of the device substrate and electrically connected to one or more corresponding device regions formed within the device substrate proximate the front surface. A back conductive layer is formed on a back surface of the device substrate. The back conductive layer is electrically connected to a device region formed within the device substrate proximate a back surface of the device substrate. One or more conductive extensions are formed on one or more corresponding sidewalls of the device substrate in electrical contact with the back conductive layer, and extend to a portion of the front surface of the device substrate. A support substrate is bonded to the back surface of the device substrate.
US08222076B2
A process for fabricating a semiconductor layer of an electronic device including: liquid depositing one or more zinc oxide precursor compositions and forming at least one semiconductor layer of the electronic device comprising predominately amorphous zinc oxide from the liquid deposited one or more zinc oxide precursor compositions.
US08222069B2
An image sensor including a first region where a pad is to be formed, and a second region where a light-receiving element is to be formed. A pad is formed over a substrate of the first region. A passivation layer is formed over the substrate of the first and second regions to expose a portion of the pad. A color filter is formed over the passivation layer of the second region. A microlens is formed over the color filter. A bump is formed over the pad. A protective layer is formed between the bump and the pad to expose the portion of the pad.
US08222067B2
A multibit electro-mechanical memory device comprises a substrate, a bit line on the substrate, a first interlayer insulating film on the bit line, first and second lower word lines on the first interlayer insulating film, the first and second lower word lines separated horizontally from each other by a trench, a spacer abutting a sidewall of each of the first and second lower word lines, a pad electrode inside a contact hole, first and second cantilever electrodes suspended over first and second lower voids that correspond to upper parts of the first and second lower word lines provided in both sides on the pad electrode, the first and second cantilever electrodes being separated from each other by the trench, and being curved in a third direction that is perpendicular to the first and second direction; a second interlayer insulating film on the pad electrode, first and second trap sites supported by the second interlayer insulating film to have first and second upper voids on the first and second cantilever electrodes, and first and second upper word lines on the first and second trap sites.
US08222065B1
A method for forming a capacitive micromachined ultrasonic transducer (CMUT) is provided that includes forming oxide features outwardly of a CMUT control chip in a silicon wafer. The oxide features are planarized. A silicon-on-insulator (SOI) wafer is bonded to the planarized oxide features. For a particular embodiment, the SOI wafer comprises a single crystal epitaxial layer, a buried oxide layer and a silicon layer, and the single crystal epitaxial layer is bonded to the planarized oxide features, after which the silicon layer and the buried oxide layer of the SOI wafer are removed, leaving the single crystal epitaxial layer bonded to the oxide layer.
US08222064B2
A method of fabricating a compound semiconductor vertical LED is provided. A first growth substrate capable of supporting compound semiconductor epitaxial growth thereon is provided. One or more epitaxial layers of compound semiconductor material such as GaN or InGaN is formed on the first growth substrate to create a portion of a vertical light emitting diode. Plural trenches are formed in the compound semiconductor material. Passivating material is deposited in one or more trenches. A hard material is at least partially deposited in the trenches and optionally on portions of the compound semiconductor material. The hard material has a hardness greater than the hardness of the compound semiconductor. A metal layer is deposited over the compound semiconductor material followed by metal planarization. A new host substrate is bonded to the metal layer and the first growth substrate is removed. Dicing is used to form individual LED devices.
US08222059B2
In a method of manufacturing an optical device, a whole substrate is first prepared which has a plurality of regions corresponding to substrates constituting a plurality of optical devices, respectively. A plurality of chips are then mounted to the plurality of regions, respectively. A whole sealing member having a plurality of sealing members is integrally attached to the whole substrate to form an intermediate body. The intermediate body is divided into the above-described regions. Thus, the optical device having a substrate, a chip as an optical element mounted to the substrate and a sealing member with transparency provided at the substrate for the purpose of sealing the chip is manufactured. This manufacturing method improves the efficiency of manufacturing an optical device.
US08222056B2
A manufacturing method of a light-emitting diode, includes the steps of: successively growing a first clad layer, an active layer and a second clad layer on a substrate; and patterning the first clad layer, the active layer and the second clad layer into a specified plane shape, and causing at least a part of an outer peripheral part of the active layer to protrude to an outside from at least one of the first clad layer and the second clad layer.
US08222055B2
Provided are a silicon nitride layer for a light emitting device, light emitting device using the same, and method of forming the silicon nitride layer for the light emitting device. The silicon nitride layer of the light emitting device includes a silicon nitride matrix and silicon nanocrystals formed in the silicon nitride matrix. A light emitting device manufactured by the silicon nitride layer has a good luminous efficiency and emits light in the visible region including the short-wavelength blue/violet region and the near infrared region.
US08222053B2
Apparatuses and methods for manufacturing a solar cell are disclosed. In a particular embodiment, the solar cell may be manufactured by disposing a solar cell in a chamber having a particle source; disposing a patterned assembly comprising an aperture and an assembly segment between the particle source and the solar cell; and selectively implanting first type dopants traveling through the aperture into a first region of the solar cell while minimizing introduction of the first type dopants into a region outside of the first region.
US08222049B2
Microfluidic systems and methods including those that provide control of fluid flow are provided. Such systems and methods can be used, for example, to control pressure-driven flow based on the influence of channel geometry and the viscosity of one or more fluids inside the system. One method includes flowing a plug of a low viscosity fluid and a plug of a high viscosity fluid in a channel including a flow constriction region and a non-constriction region. In one embodiment, the low viscosity fluid flows at a first flow rate in the channel and the flow rate is not substantially affected by the flow constriction region. When the high viscosity fluid flows from the non-constriction region to the flow constriction region, the flow rates of the fluids decrease substantially, since the flow rates, in some systems, are influenced by the highest viscosity fluid flowing in the smallest cross-sectional area of the system (e.g., the flow constriction region). This causes the fluids to flow at the same flow rate at which the high viscosity fluid flows in the flow constriction region. Accordingly, by designing microfluidic systems with flow constriction regions positioned at particular locations and by choosing appropriate viscosities of fluids, a fluid can be made to speed up or slow down at different locations within the system without the use of valves and/or without external control.
US08222046B2
The present invention is directed to immunoassays for detecting one or more target analytes in a fluid sample wherein the detection reaction occurs on a solid support and involves an amplification system. In particular, the invention is directed to making and using a test device having at least one site for detecting the presence of at least one target analyte, wherein a conjugate comprising dextran-polystreptavidin is immobilized at the test site(s) as a capture reagent for a complex containing the target analyze.
US08222044B2
A test strip with a sample receiving chamber having a novel flared portion that terminates in a sample receiving opening. The flared portion provides a reservoir from which sample fluid can be drawn into the capillary or sample receiving chamber. The wider opening provided by the present invention is easier to “target” with a sample fluid. In preferred embodiments, the hydrophilic reagent layer extends to the dosing end or side of the test strip and further promotes wicking of the sample into the sample receiving chamber and thus reduces dose hesitation. In other preferred embodiments, a tapered dosing end is provided on the test strip in combination with the flared portion, and this combination create a test strip that will draw sample fluid into the sample receiving chamber regardless of where along the dosing edge of the test strip the fluid sample makes contact.
US08222041B2
A high electron mobility transistor (HEMT) capable of performing as a CO2 or O2 sensor is disclosed, hi one implementation, a polymer solar cell can be connected to the HEMT for use in an infrared detection system. In a second implementation, a selective recognition layer can be provided on a gate region of the HEMT. For carbon dioxide sensing, the selective recognition layer can be, in one example, PEI/starch. For oxygen sensing, the selective recognition layer can be, in one example, indium zinc oxide (IZO). In one application, the HEMTs can be used for the detection of carbon dioxide and oxygen in exhaled breath or blood.
US08222039B2
A process for purification of water soluble polymers is provided. A polymer of interest can be separated from a mixture of polymers, provided the polymer of interest differs from other polymers in the mixture in the number of reactive terminal groups. The process involves derivatizing polymers at the reactive terminal groups with a derivatizing molecule, bearing either (i) two or three cationic or anionic ionizable groups, and a group capable of covalent bonding to the reactive terminal groups or (ii) three or four ionizable groups, at least one of which is capable of covalent bonding to the reactive terminal groups; followed by ion exchange. The process allows removal of PEG from MPEG, and can be used for polymers having an average size greater than 9,000 Da Derivatization may be reversible in order to allow re-use of recovered contaminant polymers.
US08222031B2
The present invention relates to methods for cultivating dermal fibroblasts, methods for preparing in vitro dermis equivalents, methods for preparing three-dimensional in vitro skin equivalents, an in vitro dermis equivalent, a three-dimensional in vitro skin equivalent, and methods for determining the effect of a chemical substance or of an agent on human skin cells using the in vitro dermis equivalent and/or the in vitro skin equivalent.
US08222027B2
An auto-nucleating device includes a tube containing a crystalline cholesterol matrix. The ends of the tube are closed by a membrane that is impermeable to the cholesterol but permeable to liquids contained in a cryopreservation vessel. The auto-nucleating device provides a site for ice nucleation during freezing of the liquid within the vessel. One such cryopreservation vessel is a flexible vial having a closed port at one adapted to be pierced by a needle to withdraw the liquid within, and an opposite end that is initially open to receive the liquid. Another vessel includes an adaptor mounted to liquid container with a tubular branch closed by a needle septum and another tubular branch provided with a barbed fitting for engaging a flexible tube that terminates in a needle septum. In another embodiment, the vessel includes an inlet and vent branch at the top of the container and an outlet septum at a bottom opening.
US08222026B2
A membrane supported bioreactor arrangement and method for anaerobic conversion of gas into liquid products including membrane modules having hollow fibers packed across a cross sectional area of the membrane module, each of the hollow fibers formed from an asymmetric membrane wall having a porous outer layer defining biopores for retaining a porous biolayer about the outer surface of the membrane wall and a less permeable hydration layer around the hollow fiber lumen; a membrane vessel for surrounding the outside of the hollow fibers with a process gas from a gas supply conduit; and a liquid supply conduit operably connected to the hollow fibers for supplying a process liquid to the hollow fiber lumens. The gas supply conduit enables the formation of a biolayer on the outer surface of the hollow fiber wall by interaction of microorganisms with the process gas and the production of a liquid product.
US08222020B2
A novel strain of Lactobacillus fermentum, denoted strain Ess-1, which has been deposited at Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH and has been assigned accession number DSM17851. Lactobacillus fermentum, strain Ess-1, has shown valuable properties in the inhibition of Candida, and has medical uses, in particular for the treatment and/or prevention of candidasis and urinary tract infections. In addition, pharmaceutical products and articles include the novel bacterial strain.
US08222017B2
Methods for the evolution of NADPH binding ketol-acid reductoisomerase enzymes to acquire NADH binding functionality are provided. Specific mutant ketol-acid reductoisomerase enzymes isolated from Pseudomonas that have undergone co-factor switching to bind NADH are described.
US08222013B2
A novel class of bacteria is described which has improved efficiency in the production of thanol by anaerobic fermentation of substrates containing carbon monoxide.
US08222012B2
A process is provided for rapidly producing target concentrations of peroxycarboxylic acids from carboxylic acid esters. More specifically, carboxylic acid esters are reacted with a source of peroxygen, such as hydrogen peroxide, in the presence of an enzyme catalyst comprising an enzyme having identity to an acetyl xylan esterase from Lactococcus lactis having perhydrolysis activity. The polypeptide is an enzyme structurally classified as a member of the carbohydrate esterase family 7 (CE-7). The peroxycarboxylic acids produced by the present process can be used in disinfecting, bleaching, and other laundry care applications. Compositions comprising the reaction components and the peroxycarboxylic acids produced by the process are also provided.
US08222004B2
The invention relates to a method for screening a pharmaceutical for treating or preventing a neurodevelopmental disorder or a psychiatric disorder accompanied by an abnormality of oxytocin system by using an increase in expression or enzymatic activity of CD38 as an index, and a diagnosis of a predisposition to a neurodevelopmental disorder or a psychiatric disorder accompanied by an abnormality of oxytocin system by using a mutation present in a CD38 gene region as an index.
US08222001B2
The invention relates to a process for the culturing of cells, preferably E1-immortalized HER cells, more preferably PER.C6 cells in a reactor in suspension in a cell culture medium, wherein the cells produce a biological substance, preferably an antibody, wherein at least one cell culture medium component is fed to the cell culture and wherein the cell culture comprising the cells, the biological substance and cell culture medium is circulated over a separation system and wherein the separation system separates the biological substance from substances having a lower molecular weight than the biological substance and wherein the biological substance is retained in or fed back into the reactor. Preferably part of the substances of lower molecular weight is continuously removed from the cell culture.
US08221995B2
The present invention relates to methods and compositions for diagnosing SIRS, sepsis, severe sepsis, septic shock, or MODS in a subject, or assigning a prognostic risk for one or more clinical outcomes for a subject suffering from SIRS, sepsis, severe sepsis, septic shock, or MODS, the method comprising performing an immunoassay for CCL23 splice variant.
US08221991B2
The present invention relates to a novel human orphan nuclear receptor that binds to a cytochrome P-450 monooxygenase (CYP) promoter and that is activated by compounds that induce CYP gene expression. The invention further relates to nucleic acid sequences encoding such a receptor, to methods of making the receptor and to methods of using the receptor and nucleic acid sequences encoding same. The invention also relates to non-human animals transformed to express the human receptor and to methods of using such animals to screen compounds for drug interactions and toxicities.
US08221981B2
The invention relates to improved methods and compositions for the nucleic acid amplification of one or multiple variants (strains) of Human Immunodeficiency Virus (HIV) present in a sample, and preferably in a sample from a pathogen infected individual. In particular, novel primers, methods and kits for the amplification of one or more species of HIV Rev, Gag and Nef nucleic acids are provided. The amplified HIV nucleic acid can be used to identify and/or quantitate HIV variants present in a sample. Nucleic acids produced by the methods of the invention or the proteins encoded thereby can also be used directly as vaccines or to transfect/load antigen presenting cells. The loaded antigen presenting cells can be used as a vaccine for the treatment or prevention of HIV infection.
US08221973B2
Methods are provided for ascertaining the sequence of a genomic DNA sample by nicking the DNA sample with a restriction nicking enzyme, followed by nick translation with labeled nucleotides, such that the labeled nucleotides can be quantified and compared to a known, reference genome.
US08221971B2
Adenovirus serotypes differ in their natural tropism. The adenovirus serotypes 2, 4, 5 and 7 all have a natural affiliation towards lung epithelia and other respiratory tissues. In contrast, serotypes 40 and 41 have a natural affiliation towards the gastrointestinal tract. The serotypes described, differ in at least capsid proteins (penton-base, hexon), proteins responsible for cell binding (fiber protein), and proteins involved in adenovirus replication. This difference in tropism and capsid protein among serotypes has led to the many research efforts aimed at redirecting the adenovirus tropism by modification of the capsid proteins.
US08221965B2
Antireflective coating compositions and related polymers are disclosed.
US08221955B2
Methods of making ink toners for use in electrostatic imaging are disclosed.
US08221952B2
A method of charging toner particles in a liquid toner includes mixing the toner with an acid, and mixing the toner with a base that reacts with the acid to charge the toner particles. The base is added first and the acid subsequently to charge the toner particles with a positive charge.
US08221923B2
A stop method for a fuel cell system including a fuel cell unit in which hydrogen is supplied to an anode, and air is supplied to a cathode so as to generate electrical power via an electrochemical reaction. The stop method includes the steps of stopping supply of hydrogen to the anode, electrically connecting the anode and the cathode via an electrical load, and supplying air to the anode.
US08221919B2
In the production of a membrane/electrode assembly 10, a first catalyst layer 22 (a second catalyst layer 34) is formed by a process comprising steps (a) and (b). (a) A step of applying a coating fluid comprising a catalyst and an ion-exchange resin, on a substrate to form a coating fluid layer. (b) A step of disposing a reinforcing layer 24 (34) on the coating fluid layer formed in the step (a) and then, drying the coating fluid layer to form a first catalyst layer 22 (a second catalyst layer 34) The process provides a catalyst layer whereby defects such as cracks are scarcely formed in the catalyst layer, and the bond strength is high at the interface between the catalyst layer and a reinforcing layer and at the interface between the catalyst layer and a polymer electrolyte membrane.
US08221917B2
A positive active material composition for a rechargeable battery, a positive electrode including the same, and a rechargeable battery including the same, the positive active material composition including a positive active material and a surface-modified metal oxide.
US08221916B2
A method for manufacturing a lithium ion secondary battery comprises the step of sintering a laminate sandwiched by setters disposed on both sides of the laminate having only interfaces between an electrolyte green sheet and a positive electrode green sheet and/or a negative electrode green sheet. A lithium ion secondary battery manufactured by the method described above is also provided.
US08221909B2
An electronic component that includes a substrate and a phase-separated layer supported on the substrate and a method of forming the same are disclosed. The phase-separated layer includes a first phase comprising lanthanum manganate (LMO) and a second phase selected from a metal oxide (MO), metal nitride (MN), a metal (Me), and combinations thereof. The phase-separated material can be an epitaxial layer and an upper surface of the phase-separated layer can include interfaces between the first phase and the second phase. The phase-separated layer can be supported on a buffer layer comprising a composition selected from the group consisting of IBAD MgO, LMO/IBAD-MgO, homoepi-IBAD MgO and LMO/homoepi-MgO. The electronic component can also include an electronically active layer supported on the phase-separated layer. The electronically active layer can be a superconducting material, a ferroelectric material, a multiferroic material, a magnetic material, a photovoltaic material, an electrical storage material, and a semiconductor material.
US08221908B2
An organic electroluminescent element including at least an emission layer sandwiched between an anode and a cathode, wherein the emission layer comprises at least a compound represented by Formula (A),
US08221886B2
Provided is an aromatic polycarbonate resin composition containing, with respect to 100 parts by mass of a resin mixture including 60 to 99 mass % of (A) an aromatic polycarbonate resin and 1 to 40 mass % of (B) a styrene-based resin, 1 to 30 parts by mass of a compatibilizer, the compatibilizer being formed of a block or random copolymer constituted of an aromatic vinyl monomer unit and an acrylate-based monomer unit. This aromatic polycarbonate resin composition has improved transparency and improved extrusion stability.
US08221882B2
A process for producing inorganic spheres, which comprises injecting an aqueous liquid containing an inorganic compound into a laminar flow of an organic liquid which runs at a flow rate of from 0.001 to 2 m/s in a flow path through a porous membrane to form a W/O type emulsion and solidifying the aqueous liquid containing an inorganic compound in the W/O type emulsion.
US08221875B2
A varnish includes an epoxy resin, a curing agent, an accelerator agent and fillers. The fillers include sericite powders. The sericite powders have composition of SiO2 in weight ratio of 55±3%. Furthermore, the Mohs' scale of hardness of the sericite powder is between 2 to 3. Glass fabric cloth is dipped into the varnish so as to form a prepreg with better machined-work capability.
US08221874B1
A durable composite sheet is provided, with a method of manufacturing the composite sheet. The method includes using a crack-resistant reinforcement panel between a gel coat and a reinforcement panel, which may be of lauan or of other materials. At least one outer coat of material is applied onto a mold surface. A barrier layer may be formed on the outer coat, preferably by spraying. At least one coat of a resin material, containing a curable resin and optionally a filler, and a fibrous reinforcement material are applied over the outer coat (over the barrier layer if present) to form a reinforcement layer. The reinforcement panel is applied to the crack-resistant reinforcement layer, and is bonded thereto.
US08221872B2
An easy-open end comprising a resin-coated metal plate obtained by coating a metal substrate with a anti-blocking agent-containing biaxially drawn film via a primer, wherein an important feature resides in that the anti-blocking agent in the biaxially drawn film is of a spherical shape having an average particle size of 0.5 to 2.5 μm and an average particle size ratio (long diameter/short diameter) in a range of 1.0 to 1.2, and is contained at a ratio of 0.05 to 0.5% by weight in the biaxially drawn film. Even without forming a top-coat layer, therefore, the film is not scratched or the forming-tool is not damaged by the anti-blocking agent that adheres and deposits on the forming tool. Besides, the resin coating favorably adheres to the metal plate offering excellent advantage in production and in economy.
US08221865B2
To provide an optical recording medium excellent in the balance of characteristics, which has a sufficient surface hardness and of which the deformation when the environmental temperature and the environmental humidity change is small.An optical recording medium comprising a resin substrate, a recording and reading layer, a cover coat layer which is a cured product of a radiation-curable composition containing a urethane (meth)acrylate (A) and a (meth)acrylate compound (B) other than the urethane (meth)acrylate (A), and a hard coat layer having a surface hardness of at least B in this order, wherein of the cover coat layer, the ratio of the elastic modulus in tension upon absorbing water to saturation to the elastic modulus in tension at 25° C. under a humidity of 45% is at least 0.20.
US08221860B2
Multi-chamber coatings are provided. The multi-chamber coating includes a first medium and a second medium. The first medium covers at least a first portion of the second medium so as to form first and second chambers. At least one material property of the first medium is different than the second medium. The first chamber and the second chamber share a wall. The wall is configured to apply a restorative force upon deformation of the first or second chambers. The coating is configured to be attached to an object that is configured to be inserted into an orifice.
US08221859B2
The invention provides a moist wipe for cleaning a surface, the wipe comprising a sheet material premoistened with an aqueous emulsion comprising a wax and no or a low amount of silicone compounds. The wipe is used to wipe a surface, to prevent or reduce against water staining on the surface, as might arise from subsequent contact with aqueous liquids. The invention further provides a packaged product containing at least one wipe, and a method of manufacturing moist wipes.
US08221853B2
A method for forming a graphitic tin-carbon composite at low temperatures is described. The method involves using microwave radiation to produce a neutral gas plasma in a reactor cell. At least one organo tin precursor material in the reactor cell forms a tin-carbon film on a supporting substrate disposed in the cell under influence of the plasma. The three dimensional carbon matrix material with embedded tin nanoparticles can be used as an electrode in lithium-ion batteries.
US08221847B2
The present invention provides a method for providing anti-ice protection to surfaces, particularly aerodynamic surfaces, to prevent foul weather icing for extended periods of time and over repeated icing situations, comprising applying an organic polymer matrix layer to the surface where the organic polymer matrix layer comprises a homopolymer comprising up to 50% porous polymer solids having a pore size of up to 100 Angstroms and being capable of absorbing and chemically bonding an aqueous freeze-point depressant solution in amounts of up to 99.75% by weight.
US08221841B2
A gas turbine engine blade has a platform. A root depends from the platform and an airfoil extends from the platform. The airfoil has leading and trailing edges and pressure and suction sides. The blade has a substrate having a surface. A compressive stress exists below a first region of the surface. The first region extends over a majority of a streamwise perimeter of the airfoil at a location at a spanwise distance from the tip or more than 50% of a tip-to-platform span. A coating is on the surface including at the location.
US08221824B2
A method is provided for altering a drug release profile of a coating of a medical device by increasing a surface area of the coating of the medical device. The method may include indenting the coating using a crimping apparatus, a rolling apparatus, or a clamping device. The method may alternatively or additionally include changing a chemical composition of at least one coating component to increase a roughness of a texture of the coating, and/or drying or partially drying the coating before the coating impacts the medical device.
US08221808B2
Calcium additives useful for fortifying baked goods, such as bread products, with calcium are disclosed. The calcium additives are particularly useful for fortifying leavened baked goods with calcium. Methods for preparing the calcium additives and using the calcium additives to fortify baked goods are also disclosed. Generally, the calcium additives comprise intimate admixtures calcium carbonate and an acid such as citric acid.
US08221798B1
A method and solution for treating nasal infections efficiently is provided. The method includes providing a first solution comprising 0.1 to 2 wt % sodium chloride and providing a second solution comprising 2 to 8 wt % NaOCl. A first aliquot of the first solution and a second aliquot of the second solution are mixed to provide a therapeutic solution comprising at least 3-600 ppm free chlorine. The therapeutic solution is introduced into a sinus cavity containing an infection.
US08221796B2
The present invention discloses an improved copper-based fungicide/bactericide composition. The improved composition offers higher biological activity over typical copper-based products, while requiring significantly less copper in the composition. The present invention also discloses methods of making the improved copper-based fungicide/bactericide composition. The present invention further discloses methods of using the improved copper-based fungicide/bactericide composition.
US08221793B2
A composition for chemoembolotherapy of solid tumors comprises particles of a water-insoluble water-swellable synthetic anionic polymer and, absorbed therein an anthracycline. Suitably the polymer is a poly(vinyl alcohol) based polymer and the drug is doxorubicin.
US08221782B2
The present invention relates in general to implantable flexible bone composites, and method for preparing the same. The flexible bone composite includes at least one polymeric layer and at least one calcium-containing layer. The polymeric layer can be a polymeric layer including a synthetic polymer. The calcium-containing layer can include a calcium compound such as β-Ca3(PO4)2. The flexible bone composites of the invention are useful as bone void fillers and have improved handling characteristics.
US08221779B2
The present embodiment of the invention is generally directed to compositions comprising suspensions of poorly water-soluble compounds recrystallized in nanoparticulate sizes ranging from 0.1 to 5 μm. In addition, the embodiment of the invention is directed to methods for preparation and administration of these compositions to a patient for prevention and treatment of disease states. In particular, the embodiment of the invention is directed to compositions comprising suspensions of poorly water-soluble compounds, such as antimitotics and antibiotics, in nanoparticulates and methods of prevention and treatment of chronic disease states, such as cancer, by intraperitoneal and intravenous administration of such compositions.
US08221774B2
An anti-stick agent that may be incorporated into an aqueous medium to assist in the prevention of soils and bodily exudates adhering to the skin. A substrate may be utilized to assist in delivering the anti-stick agent to the skin.
US08221769B2
Therapeutic methods and microorganisms therefor are provided. The microorganisms are designed to accumulate in immunoprivileged tissues and cells, such as in tumors and other proliferating tissue and in inflamed tissues, compared to other tissues, cells and organs, so that they exhibit relatively low toxicity to host organisms. The microorganisms also are designed or modified to result in leaky cell membranes of cells in which they accumulate, resulting in production of antibodies reactive against proteins and other cellular products and also permitting exploitation of proferating proliferating tissues, particularly tumors, to produce selected proteins and other products. Vaccines containing the microorganisms are provided. Combinations of the microorganisms and anti-cancer agents and uses thereof for treating cancer also are provided.
US08221759B2
The present invention relates to the identification and cloning of a novel neutralizing human monoclonal antibody to the Respiratory Syncytial Virus. The invention provides such antibodies, fragments of such antibodies retaining RSV-binding ability, chimeric antibodies retaining RSV-binding ability, and pharmaceutical compositions including such antibodies. The invention further provides for isolated nucleic acids encoding the antibodies of the invention and host cells transformed therewith. Finally, the invention provides for diagnostic and therapeutic methods employing the antibodies and nucleic acids of the invention.
US08221729B2
Disclosed are-(2′-Hydroxy-4′-aminophenyl)benzotriazole derivatives of formula wherein R1 and R4 independently of each other are hydrogen; C1-C28alkyl; C1-C28alkoxy; C2-C28alkenyl; C2-C28alkinyl; C3-C12cycloalkyl; C3-C12cycloalkenyl; C7-C28aralkyl; C1-C20heteroalkyl; C3-C12cycloheteroalkyl; or C5-C16 heteroaralkyl; and wherein C1-C28alkyl, C1-C28alkoxy, C2-C28alkenyl and C2-C28alkinyl are unsubstituted or may be substituted by at least one C1-C5alkyl, C1-C5alkoxy or hydroxy; R2 and R3 independently of each other are hydrogen; C1-C28alkyl; C2-C28 alkenyl; C2-C22alkinyl; C3-C12cycloalkyl; C3-C12cycloalkenyl; C7-C28 aralkyl; C1-C20 heteroalkyl; C3-C12cycloheteroalkyl; C5-C16heteroaralkyl; and wherein C1-C28alkyl, C1-C28alkoxy, C2-C28alkenyl and C2-C28alkinyl are unsubstituted or may be substituted by at least one C1-C5alkyl, C1-C5alkoxy or hydroxy; or CO—R5; or R2 and R3 together with the linking nitrogen form a 5- to 7-membered, monocyclic, carbocyclic or heterocyclic ring; R5 is C1-C28alkyl; C2-C28alkenyl; C2-C28alkinyl; C3-C12cycloalkyl; C3-C12cycloalkenyl; C7-C20aralkyl; C1-C20 heteroalkyl; C3-C12 cycloheteroalkyl; C1-C5alkoxycarbonyl-C1-C5alkyl; or C5-C16heteroaralkyl; for protecting human and animal hair and skin from harmful effects of UV radiation.
US08221727B2
A comestible, water-based composition containing natural ingredients provides an effective amount of at least one active ingredient selected to reduce the proliferation of bacteria in the mouth of animals to treat and improve the dental health of animals. The composition can be administered to animals in the form of their daily intake of water and may be especially packaged for ready use and consumption by animals in pre-packaged and portable doses. Compositions containing natural ingredients and formulated as toothpastes for animal dental care are also provided.
US08221724B2
Oral compositions comprising fused silica, wherein the composition is essentially free of sodium lauryl sulfate.
US08221722B2
An oral care composition comprising a fused silica abrasive and an active.
US08221719B2
This invention relates to a group of novel chelating agents, novel chelates, biomolecules labeled with said chelates or chelating agents as well as solid supports conjugated with said chelates, chelating agents or labeled biomolecules. Especially the invention relates to novel chelating agents useful in solid phase synthesis of oligonucleotides or oligopeptides and the oligonucleotides and oligopeptides so obtained.
US08221716B2
A method of synthesizing carbon nanotubes including forming a solution including an organometallic compound containing catalyst particles and a solvent, adding at least one support to the solution, wherein the carbon nanotubes are synthesized on a surface of the at least one support, and applying radiation to the solution to which the at least one support is added.
US08221715B2
A compound containing at least two pyridinium derivatives in its molecular structure and being in a reduced form thereof may be used as a CNT n-doping material. The compound may donate electrons spontaneously to CNTs to n-dope the CNTs, while being oxidized into its stable state. An n-doped CNT that is doped with the CNT n-doping material may maintain a stable n-doped state for a long time without being dedoped even in the air and/or water. Further, the n-doped state may be easily controlled when using the CNT n-doping material.
US08221701B2
Provided is a microfluidic device that can automatically perform various types of biological blood analysis. In the microfluidic device, a specimen is centrifugally separated and the centrifugally separated specimen is diluted into various dilution ratios. Also, at least two reagents that are required for one reaction and that need to be separately stored are stored in separate chambers, and they are mixed when a reaction is needed. Thus, various conventional blood analyzing reagents can be used as they are or after being minimally processed in the microfluidic device.
US08221700B2
Systems and methods for improved measurement of absorbance/transmission through fluidic systems are described. Specifically, in one set of embodiments, optical elements are fabricated on one side of a transparent fluidic device opposite a series of fluidic channels. The optical elements may guide incident light passing through the device such that most of the light is dispersed away from specific areas of the device, such as intervening portions between the fluidic channels. By decreasing the amount of light incident upon these intervening portions, the amount of noise in the detection signal can be decreased when using certain optical detection systems. In some embodiments, the optical elements comprise triangular grooves formed on or in a surface of the device. The draft angle of the triangular grooves may be chosen such that incident light normal to the surface of the device is redirected at an angle dependent upon the indices of refraction of the external medium (e.g., air) and the device material. Advantageously, certain optical elements described herein may be fabricated along with the fluidic channels of the device in one step, thereby reducing the costs of fabrication. Furthermore, in some cases the optical elements do not require alignment with a detector and, therefore, facilitate assembly and/or use by an end user.
US08221698B2
A liquid container includes: a liquid containing chamber that is accommodated in a pressure space and is pressurized by a pressurized fluid to be introduced into the pressure space so as to discharge a liquid stored in an inside thereof; and a liquid detection portion for detecting the liquid in the liquid containing chamber, the liquid detection portion includes: a liquid detection chamber that has a liquid inlet port communicating with the liquid containing chamber and a liquid outlet port communicating with an external liquid consuming apparatus, and a volume of which changes according to a liquid pressure between the liquid inlet port and the liquid outlet port; a detection unit that is provided on one of first and second walls opposite to each other, a distance between the first and second walls changing in accordance with the change in volume of the liquid detection chamber, for detecting a vibration wave form of the liquid; and a space forming portion that, when the volume of the liquid detection chamber is minimized, forms a predetermined space between the first and second walls.
US08221688B2
An exhaust gas purification device for an internal combustion engine is provided in an exhaust passage of the internal combustion engine. The exhaust gas purification device includes an HC trapping converter comprising a carrier; an HC adsorbing layer, supported on the carrier and adapted to adsorb unburned fuel; and a ternary catalyst layer, supported on a surface of the HC adsorbing layer and adapted to oxidize and remove the unburned fuel. The HC adsorbing layer includes particulate HC adsorbents each of which has a follow space and which are stacked. The ternary catalyst layer covers the HC absorbing layer such that a thickness of the ternary catalyst layer increases from an upstream side to a downstream side of the converter in the direction of exhaust gas flow.
US08221687B2
A system and a method are provided for removing greenhouse gases, particulates and pollutants from the atmosphere utilizing a greenhouse gas collection apparatus. An atmospheric mixture is collected and progressively treated in first, second and third tube furnaces and a scrubber to produce an effluent for treatment in a chemical processing plant. The first tube furnace oxidizes hydrocarbons, the second tube furnace oxidizes any remaining nitrous and nitric oxides, and the third tube furnace oxidizes sulfur dioxide. The scrubber precipitates carbon dioxide as calcium carbonate. A vacuum pump draws the atmospheric mixture through tube furnaces and the scrubber.
US08221683B2
Provided is a specimen preparation apparatus capable of supplying a specimen from the specimen preparation apparatus to a specimen analyzer without burdening an operator. This specimen preparation apparatus comprises a stained specimen preparation part for preparing a specimen on a slide glass and staining the specimen, a keeping part for storing the stained specimen slide glass prepared in the stained specimen preparation part and a control part for deciding whether to supply the stained specimen slide glass to the keeping part or to the external apparatus.
US08221673B2
The present invention provides a method for producing an injection molded panel member having a first portion, a second portion, and an appearance surface portion. The method includes placing the appearance surface portion of the panel member into a mold cavity. The mold cavity preferably includes a first chamber adapted to form the first portion of the panel member, and a second chamber adapted to form the second portion of the panel member. After the appearance surface portion of the panel member is inserted into the mold, molten plastic material and pressurized gas are injected into the first chamber of the mold cavity. After the molten plastic material is injected into the first chamber of the mold, molten plastic material is injected into the second chamber of the mold cavity. The molten plastic is then cooled until it solidifies. After the molten plastic is sufficiently cooled, the pressurized gas is vented and the panel member is removed from the mold.
US08221664B2
A hot axial pressing method for sintering a ceramic powder, particularly doped Gd2O2S, comprises the step of placing a first porous body (7), the ceramic powder (9) and a second porous body (7) into a mould shell (5) supported by a support (13, 14). The ceramic powder (9) is located between the porous bodies (7). Gaseous components are evacuated from the ceramic powder (9) up to an ambient pressure of less than 0.8 bar. The porous body (7) and the ceramic powder (9) are heated to a maximum temperature of at least 900° C. and are applied to a pressure up to a maximum pressure of at least 75 Mpa. According to the invention the variation in time of the heating step and the variation in time of the pressure applying step is adjusted to each other such that the mould shell 5 is held by the porous bodies (7) and/or the ceramic powder (9) in a state where the mould shell (5) and the support (13, 14) are disconnected with respect to each other.
US08221661B2
The invention relates to the building material industry and to the use of labor saving tools of industrial continuous and batch brick kilns. Said invention makes it possible to develop a process for producing large-sized clay ceramic products consisting in carrying out rapid and high-quality baking and to accelerate a construction process. The inventive method for producing a clay house or another clay construction consists in forming, during construction, through and blind voids in a wall and a ceiling in such a way that they are closed with a noncombustible material from outside, in covering window and door apertures in the ready clay construction with a noncombustible material, and in baking the construction to a ceramic state in such a way that hot gas penetrates into the voids and that the body of the product is uniformly heated. During baking the construction is used in the form of a furnace (combustion chamber).
US08221648B2
The present invention include fluorescent nanocrystals which have high fluorescence intensity, are water soluble, exhibit physical and chemical stability, and whose spectral properties are detectably modified as the size of functional groups bonded to the nanocrystal surface change when contacted with target molecules in a sample. The molecules in the sample add to or reduce the size of functional groups on the fluorescent nanocrystal proportional to the activity and amount of the target molecules. The present invention may be used to detect telomerase in a sample.
US08221645B2
Disclosed is a heat dissipating material which is interposed between a heat-generating electronic component and a heat dissipating body. This heat dissipating material contains (A) 100 parts by weight of a silicone gel cured by an addition reaction having a penetration of not less than 100 (according to ASTM D 1403), and (B) 500-2000 parts by weight of a heat conductive filler. Also disclosed is a semiconductor device comprising a heat-generating electronic component and a heat dissipating body, wherein the heat dissipating material is interposed between the heat-generating electronic component and the heat dissipating body.
US08221642B2
A method for removing a plurality of dielectric films from a supporting substrate by providing a substrate with a dielectric layer overlying another dielectric layer, contacting the substrate at a first temperature with an acid solution exhibiting a positive etch selectivity at the first temperature, and then contacting the substrate at a second temperature with an acid solution exhibiting a positive etch selectivity at the second temperature. The dielectric layers exhibit different etch rates when etched at the first and second temperatures. The first and second acid solutions may contain phosphoric acid. The first dielectric layer may be silicon nitride and the second dielectric layer may be silicon oxide. Under these conditions, the first temperature may be about 175° C. and the second temperature may be about 155° C.
US08221638B2
Prior to wafer processing, pressure ratio control is executed on a divided flow rate adjustment means so as to adjust the flow rates of divided flows to achieve a target pressure ratio with regard to the pressures in the individual branch passages. As the processing gas from a processing gas supply means is diverted into first and second branch pipings under the pressure ratio control and the pressures in the branch passages then stabilize, the control on the divided flow rate adjustment means is switched to steady pressure control for adjusting the flow rates of the divided flows so as to hold the pressure in the first branch passage at the level achieved in the stable pressure condition. Only after the control is switched to the steady pressure control, an additional gas is delivered into the second branch passage via an additional gas supply means.
US08221636B2
A magnetic head includes a pole layer, and an encasing layer having a groove that accommodates the pole layer. A manufacturing method for the magnetic head includes the steps of forming a nonmagnetic layer that will later undergo formation of the groove therein and will thereby become the encasing layer; forming the groove in the nonmagnetic layer so that the nonmagnetic layer becomes the encasing layer; and forming the pole layer such that the pole layer is accommodated in the groove of the encasing layer. The nonmagnetic layer is formed of Al2O3. The step of forming the groove in the nonmagnetic layer includes the step of taper-etching the nonmagnetic layer by reactive ion etching with an etching gas containing at least BCl3 and N2 among BCl3, Cl2 and N2.
US08221635B2
A process for manufacturing a printed wiring board includes specifying overlapping etches for a first portion of the printed wiring board and a second portion of the printed wiring board, the first portion of the printed wiring board having disposed thereon a printed circuit having at least one dimension critical to printed wiring board operation, etching a first conductor in the first portion of the printed wiring board when a first conductor thickness is a predetermined thickness, completing all plating steps, and etching a second conductor in the second portion of the printed wiring board.
US08221624B2
A system for separating liquids of different densities employs a collector shell (17) made up of smooth lines and curvatures. A fairing creates and controls the flow of the liquids (for example water and oil) by gathering, capturing and isolating one liquid beneath the surface of the other liquid (24). The trapped and water pressurized oil is extracted and transferred to a storage container (21). One embodiment, the collector shell (17) is a simple design yet complex in achieving a workable shape that can accomplish all of the above using a small number of moving parts all of which, with the possible exception of the collector shell (17) and the elevator screw (12) are off the shelf items. The collector shell (17) inherently suppresses turbulence. The accumulation of oil captured in the collector bowl (17d) remains in a state of semi-suspension in both rough and normal surface conditions. The only movement of the oil is in a vertical direction when the elevator screw (12) is in motion.
US08221619B2
A fluid filter and an end cap of the fluid filter are described. The filter may be a spin on oil filter, which includes a combination dual valve element defining an integral anti-drain back valve and an integral relief valve, a retainer assembly for maintaining the combination dual valve element in position in the end cap, relative to the filter. The combination dual valve element includes an ADB sealing lip forming an anti-drain back valve portion, and an RV sealing lip forming a relief valve portion.
US08221616B2
A control valve assembly (10) controls the flow of water to and from a treatment tank (16) and the regeneration of the treatment material therein. A housing of the valve assembly includes connections for a tank inlet and tank outlet. An inlet chamber (60), outlet chamber (34), a pressure-operated inlet valve (24) and an outlet valve (32). A pair of venturi chambers (81a, 81b) are configured to provide co-current and counter-current regeneration. A regeneration control subsystem includes a turbine (104) and a nozzle impinging thereon to produce rotation. An external port (130) receives fluid to provide a driving for the turbine in order to initiate regeneration. A bypass chamber (60) communicates with the inlet chamber (15). The inlet valve (24) has dual seating surfaces for controlling the communication between the inlet chamber, transfer chamber (70) and tank inlet (26).
US08221611B2
A device which is suitable for electrochemically processing an object comprises at least an electrolyte-containing chamber, means for supporting the object to be processed in the chamber, a counter electrode disposed in the chamber as well as means for applying an electrical potential difference between the object to be processed and the counter electrode. The device furthermore comprises at least one holder and at least one rod-shaped coelectrode supported by the holder, which rod-shaped coelectrode extends towards the object and which in use has a polarity opposite that of the counter electrode.
US08221604B2
Transfer of fluid substances, and/or substances comprised in fluid substances, is controlled by introducing a separation medium, which prevents transfer of the fluid substances, and/or the substances comprised in the fluid substances, to an intermediate cavity connecting a first cavity and a second cavity; and introducing a connection medium to replace the separation medium and thereby start substance transfer to the second cavity. Substance transfer may be readily controlled without relying on mechanical means. Based on the present invention, two-dimensional electrophoretic analysis can be readily implemented on a chip.
US08221603B2
A surface-contact sensor includes a housing defining an opening, an ion-permeable membrane at the opening, a counterelectrode within the housing, and a reference electrode within the housing that is spaced apart from the current-collector. A current-collector pad includes a grommet support having a base and a lumen defining an opening. An ion-permeable membrane spans at least a portion of the opening of the grommet. The ion-permeable membrane is held in place by a gasket surrounding the lumen. A current collector, at least in one embodiment, is proximate to a portion of the ion-permeable membrane that spans the opening.
US08221595B2
The invention provides a method for forming a patterned material layer on a structure, by condensing a vapor to a solid condensate layer on a surface of the structure and then localized removal of selected regions of the condensate layer by directing an ion beam at the selected regions, exposing the structure at the selected regions. A material layer is then deposited on top of the solid condensate layer and the exposed structure at the selected regions. Then the solid condensate layer and regions of the material layer that were deposited on the solid condensate layer are removed, leaving a patterned material layer on the structure.
US08221587B2
The invention consists in the use, in a method for manufacturing a sheet of paper, of an aqueous suspension and/or dispersion of mineral materials as an agent for slowing the penetration of the paper coating into said sheet, characterized in that said suspension and/or dispersion contains at least one water-soluble copolymer made up of at least one ethylenically-unsaturated anionic monomer, and at least one ethylenically-unsaturated oxylalkylated monomer terminated by a hydrophobic chain.It also consists in a method for manufacturing a sheet of paper which implements said copolymer, as well as the sheet of paper obtained.
US08221586B2
The invention relates to improvements in security substrates and in particular to fibrous security substrates, such as paper, incorporating a watermark. The security substrate comprises a fibrous base layer, having a normal base fiber density, said base layer incorporating a watermark consisting of a plurality of alphanumeric characters. Each character comprises dark and/or light regions, the dark regions being formed by more densely deposited fibers than the normal base fiber density and the light regions being formed by less densely deposited fibers than the normal base fiber density. The density of the fibers in any region is substantially uniform such that there is no gradual change of tone between the light and dark regions. Each dark and light region adjoins at least one light and dark region respectively and an area of normal fiber density.
US08221565B2
Methods of making and resultant compositions thereof, which include a gas generant having a coating including an inorganic combustion inhibitor. Such coated gas generants are useful in pyrotechnic compositions and ignition materials, and may be employed, for example, in inflatable restraint systems. The ratio of coated and uncoated gas generant bodies within an airbag inflator may be tailored to provide S-curve inflation performance. Spray application of aqueous mixture including the combustion inhibitor onto the gas generant body provides a rapid way to achieve a thin but robust coating.
US08221562B2
A method for casting medium carbon, B/Ti steel product using compact strip processing or thin slab casting. The method can include providing a steel composition including boron and titanium and casting the steel composition into a slab having a thickness between about 25 and 150 mm. The slab can have a cast composition including about 0.23 to 0.30 wt. % carbon, about 0.0010 to 0.0050 wt. % boron, about 0.010 to 0.050 wt. % titanium, about 1.15 to 1.50 wt. % manganese, less than 0.35 wt. % silicon and a Ti/N ratio greater than 2.9. The amount of each element is provided based upon the total weight of the steel composition. The steel slab can be free from cracks and significant defects. Furthermore, the steel slab can be used for electric resistance welded (ERW) products.
US08221560B2
Disclosed herein are a lead-free solder alloy and a manufacturing method thereof. More specifically, disclosed are: a lead-free solder alloy, which comprises 0.8-1.2 wt % silver (Ag), 0.8-1.2 wt % copper (Cu), 0.01-1.0 wt % palladium (Pd), 0.001-0.1 wt % tellurium (Te), and a balance of tin (Sn), and thus has a melting point similar to those of prior lead-free solder alloys, excellent wettability, very low segregation ratio, and excellent weldability with a welding base metal, such that it improves temperature cycle performance and drop impact resistance simultaneously, when it is applied to electronic devices and printed circuit boards; a manufacturing method of the above alloy; and electronic devices and printed circuit boards which include the same.
US08221546B2
A method of epitaxially growing a SiC layer on a single crystal SiC substrate is described. The method includes heating a single-crystal SiC substrate to a first temperature of at least 1400° C. in a chamber, introducing a carrier gas, a silicon containing gas and carbon containing gas into the chamber; and epitaxially growing a layer of SiC on a surface of the SiC substrate. The SiC substrate is heated to the first temperature at a rate of at least 30° C./minute. The surface of the SiC substrate is inclined at an angle of from 1° to 3° with respect to a basal plane of the substrate material.
US08221544B2
A polycrystalline film is prepared by (a) providing a substrate having a thin film disposed thereon, said film capable of laser-induced melting, (b) generating a sequence of laser pulses having a fluence that is sufficient to melt the film throughout its thickness in an irradiated region, each pulse forming a line beam having a predetermined length and width, said width sufficient to prevent nucleation of solids in a portion of the thin film that is irradiated by the laser pulse, (c) irradiating a first region of the film with a first laser pulse to form a first molten zone, said first molten zone demonstrating a variation in width along its length to thereby define a maximum width (Wmax) and a minimum width (Wmin), wherein the first molten zone crystallizes upon cooling to form one or more laterally grown crystals, (d) laterally moving the film in the direction of lateral growth a distance that is greater than about one-half Wmax and less than Wmin; and (e) irradiating a second region of the film with a second laser pulse to form a second molten zone having a shape that is substantially the same as the shape of the first molten zone, wherein the second molten zone crystallizes upon cooling to form one or more laterally grown crystals that are elongations of the one or more crystals in the first region.
US08221542B2
The present invention describes a fire resistant building material composition, useful for example as a fire door core and to a method of making this composition. The building material of the present invention is prepared from an aqueous mixture of predominately expanded perlite, a small amount of a binder component consisting essentially of calcined gypsum and an organic binder, and optionally a fibrous reinforcement.
US08221538B2
The invention relates to an aqueous pigment preparation, containing (A) at least one organic and/or inorganic pigment, (B) a dispersing agent of the formulas (I), (II), (III) or (IV), or mixtures of the dispersing agent of the formulas (I), (II), (III) or (IV), (C) optionally a wetting agent (D) optionally further surfactants and/or dispersing agents, (E) optionally one or multiple organic solvents, or one or multiple hydrotropic substances, (F) optionally further additives common for the production of aqueous pigment dispersions, and (G) water.
US08221529B2
In an embodiment, a dialysis fluid cassette is disclosed. The cassette includes a plurality of walls defining at least one valve chamber, a dialysis fluid inlet, a dialysis fluid outlet and a dialysis fluid pathway. The cassette further includes a baffle extending from a first one of the walls to an opposing second one of the walls. The baffle includes an end fixed to a third one of the plurality of walls and a free end. The fixed end separates the dialysis fluid inlet from the dialysis fluid outlet and the baffle and the plurality of walls are constructed and arranged such that the flow of dialysis fluid along the pathway defined in part by the baffle slows as the flow approaches the free end of the baffle.
US08221522B2
The present invention describes a system and method for accurately measuring the pressure within a filter housing. A pressure sensor and a communications device are coupled so as to be able to measure and transmit the pressure within the filter housing while in use. This system can comprise a single component, integrating both the communication device and the pressure sensor. Alternatively, the system can comprise separate sensor and transmitter components, in communication with one another. In yet another embodiment, a storage element can be added to the system, thereby allowing the device to store a set of pressure values. The use of this device is beneficial to many applications. For example, the ability to read pressure values in situ allows integrity tests to be performed without additional equipment. In addition, integrity testing for individual filters within multi-filter configurations is possible.
US08221516B1
A bactericidal and fungicidal composition having fertilizer properties, the composition containing a percentage of potassium polyposphite is disclosed. The composition is useful as a fungicide, bactericide, and as a fertilizer for application to plants and, particularly, commercial crops. A method of making the polyposphite composition is described, as well as methods of using same.
US08221513B2
Systems and processes for producing synthesis gas. A carbonaceous feedstock can be combined with one or more low-oxygen carrier fluids having a high heating value. The feedstock and carrier fluid, in the presence of one or more oxidants, can be gasified to provide a synthesis gas. In one or more embodiments, at least a portion of the synthesis gas can be recycled for use as the carrier fluid.
US08221512B2
Provided is a hydrogen generator capable of suppressing degradation in capability of a hydrogen generator which is caused by crush of particulate reforming catalyst and of suppressing decrease in reforming efficiency due to decrease in heat transfer efficiency of a catalyzing portion which is caused by the crush of the particulate reforming catalyst. A hydrogen generator comprises a catalyzing portion 50 having particulate reforming catalyst P, and a combusting portion 5 for heating the catalyzing portion 50, the hydrogen generator being configured to generate a reformed gas containing hydrogen while flowing a material gas containing steam in a direction in which the catalyzing portion 50 extends. The catalyzing portion 50 includes a separating member 40. The separating member 40 is disposed on a separating cross-section which is a cross-section of the catalyzing portion 50 in a direction perpendicular to the direction in which the catalyzing portion 50 extends. A plurality of air holes 40D having a shape to inhibit passage of the particulate reforming catalyst P are provided on the separating member 40. An opening having a shape to permit passage of the particulate reforming catalyst P is provided on the separating cross-section.
US08221506B2
The prosthetic foot (1) consists of three or four laminas, a lower lamina (1a) defining the under-heel and the foot front, a rear lamina (1b) defining the heel and functioning as the Achilles tendon and as the soleus muscle, two upper laminas (1c and 1d) defining the front part of the foot and performing the function of the front tibial muscle, and a connector (2) in proximity to the ankle to serve as a coupling for a tube (3).
US08221501B2
An expandable intervertebral implant including a body having a longitudinal axis and including first and second axial walls spaced apart along a transverse axis, and first and second transverse end walls extending between and interconnecting the first and second axial walls. The intervertebral implant includes an expansion member co-acting with the axial walls to expand the body along the transverse axis.
US08221497B2
The middle ear prosthetic device comprises: a columellate prosthesis arranged to replace the ossicular chain of the middle ear with the exception of the stapes footplate or the entire stapes, a first end of this prosthesis being intended to be inserted into a hole provided in the footplate or to rest on the footplate itself, or to be connected to the stapes capitellum respectively; an annular element of bioinert metal insertable into the auditory tube at the position in which the neotympanum is to be formed; a tensostructure of non-reabsorbable bioinert material, which extends into the interior of the annular element and is fixed to this latter, the tensostructure presenting apertures which provide the surgeon with a sufficient view of the surgical field and allow the required surgical manoeuvres; first and second means for connecting the second end of the columellate prosthesis and the neotympanum to the tensostructure respectively.
US08221492B2
An expandable venous valve having a support structure that configured to enlarge the area adjacent to the valve structure such that the flow patterns of retrograde flow are modified in a way that facilitates the flushing of the pockets at the base of the valve area to prevent stagnation of bodily fluid, which in the venous system, can lead to thrombus formation. The enlarged pocket areas can be created by forming an artificial sinus adjacent the valve structure in an unsupported section of vessel wall between two support frame section or the support frame can comprise an expanded-diameter intermediate or proximal section that forms an artificial sinus adjacent the valve structure. In another group of embodiments, the attachment pathway between opposing leaflets and the support frame and/or vessel wall comprises a proximal portion that places the leaflets in extended contact with one another and a distal portion forms a large angle with respect to the adjacent walls such that a large pocket is created at the base of the leaflets. In one embodiment, the attachment pathway extends distally along a pair of substantially parallel longitudinal attachment struts to create an extended leaflet contact area, then angles circumferentially and distally from the former along distal attachment struts to define the bottom edge of the leaflets.
US08221480B2
Certain embodiments disclosed herein relate to compositions, methods, devices, systems, and products regarding frozen particles. In certain embodiments, the frozen particles include materials at low temperatures. In certain embodiments, the frozen particles provide vehicles for delivery of particular agents. In certain embodiments, the frozen particles are administered to at least one biological tissue.
US08221472B2
A bone anchor (100) for attaching a rod (108) to a bone has an anchor member (106) for attachment to the bone and an anchor head (104) having a U-shaped opening for receiving the rod. The bone anchor also includes a locking cap (102) that has a main body (900) and a set screw (1000). Advantageously, in one embodiment the locking cap preferably is designed such that a single tool can be used to lock the locking cap in place on the anchor body preferably with a 90° turn and preferably then drive the set screw to clamp the rod. The locking cap also preferably non-threadingly engages the anchor body. The anchor body preferably has an inclined surface on its top surface which elastically deflects extending tabs on the main body to secure the locking cap to the anchor body. A method of implantation and assembly of the bone anchor are also described.
US08221467B2
A dynamic spine stabilization element of a spine stabilization assembly includes first and second spinal rod segments that are coupled to one another via a connector. The connector allows movement of a spinal rod segment with respect to the coupling device and/or with respect to another spinal rod segment. This provides limited angulation (e.g. bending) between spinal rod segments allowing for limited movement of the vertebra connected by the present dynamic stabilization element. The connector may allow pivoting motion of the rod segments relative to the coupling device and relative to the other rod segment such as pivoting motion of one rod segment in a first plane and pivoting motion of the other rod segment in a second plane that is perpendicular to the first plane. The connector may also be bendable or flexible. In this form, the connector allows limited flexing, bending or angulation as between the associated spinal rod segments during use. Moreover, ends of the spinal rod segments may be configured to prevent or limit rotation of the spinal rod segments. The configured ends may cooperate with the coupling device to achieve the limitation on rotational movement.
US08221457B2
The present invention relates to an osteosynthesis device, particularly for spinal support or correction, enabling easier and compact implantation, that can be particularly used in the case of implantation via the anterior approach, and a preassembly method for such a device. Said device comprises implants screwed into two vertebrae and one plate characterized in that the plate is joined to at least one implant by attachment structure able to hold said plate without preventing the implant from rotating on its screwing axis, or without preventing a specified clearance of the plate with respect to the implant. In this way, said attachment structure make it possible to continue screwing the implant, or adjust the position of the plate after the plate has been on the implant.
US08221443B2
Kits and methods for submucosal endoscopic access into body cavities such as the peritoneal cavity and the posterior mediastinum through a submucosal endoscopic procedure in which an opening is formed through the muscularis propria within a bleb. The procedure may result in a mucosal flap formed by separated mucosal tissue within the bleb and the mucosal flap may be advantageously used to assist in closure of the opening.
US08221438B2
Devices and methods for reducing a size of a lumen are provided. In one embodiment, a lumen reduction device is provided having an end effector with a trough formed therein for receiving tissue surrounding a lumen, and a plurality of fasteners configured to engage the tissue disposed within the trough. In use, the end effector can be actuated to deliver the fasteners to the tissue, and one or more sutures coupled to the fasteners can be used to pull the fasteners together and thereby cinch the tissue to reduce the size of a lumen.
US08221437B2
A liquid delivery wand includes a centrally located fluid storage chamber. An absorbent pad is located within the working end of the wand for applying the treatment liquid to the skin while a vacuum is applied to the skin through an abrasive coated treatment tip. Coaxial, cylindrical tubes with flow channels between tube surfaces control the flow rate, the pressure drop being established by the close fit and length of adjacent surfaces of the coaxial components. The flow rate of the liquid is adjustable by simply rotating the interfitting components. The chamber that holds the liquid is sealed from the atmosphere at the distal and proximal end. When the wand is connected to vacuum and the distal end contacts the skin, the vacuum applies a negative pressure to the fluids within a fluid chamber. A small portion of liquid is thus transferred to wet the filter pad.
US08221418B2
The present disclosure relates to various apparatus, systems and methods of identifying and treating tissue using at least one electrical property of tissue. Provided is a method for identifying and treating tissue, the method including providing a electrosurgical treatment device including an electrode assembly for measuring one or more electrical properties of a target tissue, the electrode assembly being mounted on a distal end thereof, measuring the one or more electrical characteristics of the target tissue, comparing the measured electrical property values of the target tissue against electrical property values of known tissue types, identifying a tissue type of the target tissue, adjusting an energy delivery configuration of the electrosurgical treatment device to the type of target tissue, and activating the electrosurgical treatment device to treat the target tissue.
US08221413B2
A method and apparatus of treating tissue adjacent to a bodily conduit using thermotherapy, while preventing obstructions of the bodily conduit due to edema employs the circulation of warmed fluid to maintain the temperature of the bodily conduit walls and compresses the tissue to be treated to increase the effectiveness of the irradiated heat. An energy-emitting source containing catheter is inserted in a bodily conduit and is positioned in a region of the tissue to be treated so that the energy-emitting source radiates energy to the tissue to be treated. Fluid warmed to over 30° C. is circulated into and through the catheter to warm walls of the bodily conduit adjacent the catheter. The circulated fluid inflates a balloon to a pressure to compress the tissue to be treated. The combination of warmed fluid over 30° C. being circulated adjacent the bodily conduit to maintain the warmth in its walls and the compression of the tissue to be treated enables a natural stent to be formed that remains after the catheter and compression balloon is removed.
US08221412B2
A device for penetrating tissue includes an elongated element having a distal end, a proximal end, a body extending between the distal and the proximal ends, and a lumen located within at least a portion of the body, wherein the lumen has a cross-sectional shape that is a polygon. A device for penetrating tissue includes an elongated element having a distal end, a proximal end, and a body extending between the distal and the proximal ends, at least a portion of the body having a cross-sectional profile that is a polygon, wherein the elongated element is a cannula.
US08221410B2
A method of creating a tissue effect at a tissue site delivers electromagnetic energy through a skin surface from an electromagnetic energy delivery device coupled to an electromagnetic energy source. At least one of the electromagnetic energy delivery device or electromagnetic energy source includes a memory. A reverse thermal gradient is created through the skin surface to sufficiently heat an underlying tissue site to provide that a temperature of the skin surface is lower than a temperature of the underlying tissue. Information is stored from the memory to facilitate operation of at least one of the electromagnetic energy delivery device or the electromagnetic energy source. Electromagnetic energy is applied through the skin surface to the underlying tissue. A tissue effect is created on at least a portion of the tissue site.
US08221396B2
Described herein are devices, systems and methods for treating disease and/or infection by the release of silver from an implant over an extended period of time. In particular, the devices described herein may be used to treat infections such as osteomyelitis by the controlled release of silver ions from multiple sites of an extended-use implant. This implant typically includes a plurality of arms that both anchor and help distribute the released ions within the tissue. Power may be applied to release the silver ions into the tissue.
US08221386B2
A medication-delivery method relating to an infusion device specifically adapted for syringe injections.
US08221384B2
Disclosed is an anastomosis catheter, for achieving a tissue to tissue or synthetic graft to tissue attachment. The catheter includes a plurality of deployable tissue anchors, which may be laterally deployed into surrounding tissue. The anchors may be used to achieve end to end or end to side anastomoses. Methods are also disclosed.
US08221383B2
The invention provides a medical device having a catheter and one or more expandable constricting/occluding members. The catheter has a lumen communicating with a port at its distal end. The lumen and port are adapted for introduction of therapeutic or diagnostic devices, including an angioplasty/stent catheter and an atherectomy catheter, into a vertebral or basilar artery. The constrictor/occluder is mounted proximal to the port of the catheter. Manometers may be mounted distal to one or more constrictors for measuring pressure distal to the constrictor(s). Methods of using the devices for preventing distal embolization during vertebral and/or basilar procedures by reversing blood flow in the vertebral artery toward the subclavian artery are disclosed.
US08221382B2
A system for mixing or reconstituting a drug contained in a first container with a diluent or fluid contained in a second container. The second container has a port docking assembly for engaging the first container. The first container is rotatable and axially slidable within the port docking assembly. The port docking assembly has an actuator to urge a stopper fluidly sealing the first container into the interior of the first container. The port docking assembly further includes a movable plug constructed to fluidly seal the second container in a first, docked position and to provide access to the interior of the second container in a second, activated position, whereby fluid communication between the first and second containers is provided when the first and second containers are in the second, activated position.
US08221379B2
A disposable absorbent article may comprise a chassis and an ear. The chassis comprises a liquid permeable topsheet, a backsheet, and an absorbent core disposed between the topsheet and backsheet. The ear comprises an elastomeric material and a first substrate joined to the elastomeric material. The ear has a first void region adjacent the proximal edge of the ear. The ear is joined to the chassis by at least one mechanical bond that engages the elastomeric material.
US08221370B2
In a personal care article for contact with human skin, a non-woven substrate of the article has a longitudinal direction, a transverse direction and at least one skin-contact surface. A plurality of surface features is disposed on the at least one skin-contact surface in a sinusoidal wave-form along at least one of the longitudinal direction and the transverse direction of the substrate. The surface features have a height that generally defines an amplitude of the sinusoidal wave-form, and are spaced from each other a spatial distance. This spatial distance is at least in part a function of a movement speed at which the article is to be moved relative to the skin while in contact therewith. In one method of making such a substrate, the movement speed and a temporal frequency are selected and used to determine the spacing between surface features on the skin-contact surface of the substrate.
US08221362B2
The disclosures made herein relate to an infusion device specifically adapted for syringe injections. In one embodiment of the disclosures made herein, an infusion device comprises a body including an accessible surface having a single inlet port therein, an engagement surface having a single outlet port therein, a medication delivery channel extending between the single inlet port and the single outlet port, and an identification feature on the accessible surface of the body adjacent to the single inlet port. The single inlet port of the medication delivery channel is tapered thereby forming a funnel-shaped entry into the medication delivery channel. A cannula is coupled to the body at the single outlet port and is adapted for receiving medication from the single outlet port and transmitting the medication therethrough.
US08221360B2
A disposable clip (10) is used to releasably attach an ampoule (13) to a syringe (11). The clip (10) includes an ampoule engaging portion (19) and a syringe engaging portion in the form of a recess (17). The ampoule engaging portion (19) comprises a compressible projection which is inserted into the neck (21) of the ampoule (13). The ampoule engaging portion (19) is thereby compressed and frictionally engages the inside of the neck (21) to secure the ampoule (13) firmly to the clip (10). The clip (10) does not obscure the label on the ampoule (13).
US08221356B2
A medication delivery system, comprising: a movable part (230, 232) adapted to move relative to a stationary part; at least two conductors (234, 236) which are arranged such that an electrical characteristic is defined by the mutual position of the movable and the stationary part and/or by movement of one of said parts relative to the other; and a detector for detecting a change of said electrical characteristic, wherein the parts are stationary relative to each other during dose setting and in that the parts are moved relative to each other during dose ejection, such that that detector provides a signal indicative of the actual amount of the ejected dose.
US08221353B2
An intravitreal injection system for administering a pharmacological agent formulation to an intravitreal compartment of an eye, comprising (i) an injection member coupled to, or comprising, an internal formulation chamber that is adapted to receive and contain the pharmacological agent formulation therein, (ii) a needle having a first end that is in communication with a formulation chamber and a second injection end, and (iii) a movable platform for positioning the system on the eye, guiding the needle, and limiting the penetration depth of the needle into the eye.
US08221349B2
An inflatable bone tamp for performing a minimally invasive surgical procedure includes an inflatable structure having at least three contiguous lobes, that when inflated, cause the inflatable structure to exhibits an outwardly tapering expansion profile. By forming the inflatable structure such that the reduced-diameter junction(s) between the lobes has a greater wall thickness then the adjacent lobes, the durability and abrasion-resistance of the inflatable bone tamp can be increased.
US08221348B2
An evacuation sheath assembly and method of reducing or removing a blockage within a vessel without permitting embolization of particulate matter is provided. The evacuation sheath assembly includes a first elongate tubular member, having proximal and distal ends and a main lumen configured to be placed in fluid communication with a blood vessel. An expandable member is provided on a distal portion of the tubular member and is configured to form a seal with the blood vessel. The evacuation assembly further includes a second elongate tubular member having proximal and distal ends and an inflation lumen configured to be placed in fluid communication with the expandable member and a gas inflator. The gas inflator includes a high pressure gas source and a mechanism for regulating the pressure of the gas delivered by the gas inflator. The gas inflator is configured to be placed in fluid communication with the proximal end of the inflation lumen in order to provide a regulated pressure gas source for inflating the expandable member. A method of treatment of a blood vessel using the evacuation sheath assembly includes advancing the evacuation sheath assembly into the blood vessel through a guide catheter. The expandable member is inflated to provide form a seal between the blood vessel and the guide catheter and a vacuum is applied to the main lumen of the first elongate tubular member to cause retrograde blood flow and carry fluid into the main lumen of the evacuation sheath assembly.
US08221345B2
An apparatus comprising a pump configured to deliver insulin, an input configured to receive blood glucose data, a user interface, and a controller communicatively coupled to the pump, the input, and the user interface. The controller includes a blood glucose data module to compare the blood glucose data to a target blood glucose level for an insulin pump user. The controller is configured to present a question related to the blood glucose level via the user interface when the blood glucose level is different than the target blood glucose level, receive a response to the question via the user interface, and present a recommended user action based at least in part on the response. Other devices, systems, and methods are disclosed.
US08221341B1
An ankle-foot orthotic device incorporating an adjustable response system allowing the hindfoot to recognize that the foot landed on the heel during a walking sequence is provided. The device is constructed to provide feedback for the patient to make adjustments needed throughout the body structures to prepare for weight transfer onto the foot during gait. The system also helps the patient to maintain toe extension during a walking sequence. The device generally incorporates an articulated foot support and a foot support insert configured to substantially inhibit supination or pronation of the mid foot.
US08221333B2
A puncturing system includes a support tape (1) that supports a plurality of lancets (2), a first reel (3) onto which the support tape (1) with unused lancets (2) is wound, a second reel (4) on which portions of the support tape with used lancets (2) are to be wound, a winding mechanism which, by turning the second reel (4), brings the lancets (2) supported by the support tape (1) to a position of use one after another and thus unwinds the support tape (1) from the first reel (3) and winds it onto the second reel (4), and a puncturing drive mechanism (7) with which lancets (2) located in the position of use are accelerated in order to puncture the skin. The support tape (1) between the first and second reels (3, 4) is twisted only in one direction of rotation by at least a quarter turn, preferably by at least a half turn.
US08221330B2
The invention relates to a method and apparatus for assessing the reactivity observable in a certain physiological signal, especially the EEG signal, of a comatose subject. In order to obtain an objective and a reliable measure of the reactivity automatically and without the presence of a trained EEG specialist, a valid signal model is constructed for an EEG signal obtained from the subject. A time reference corresponding to a stimulus is applied and further signal data is obtained from the time series, the further signal data being subsequent to the time reference. By employing the further signal data, the method tests whether the signal model remains to be a valid signal model for the EEG signal also after the stimulus, and indicates, based on the test, whether reactivity is present in the physiological signal.
US08221326B2
In accordance with an embodiment of the present technique, there is provided methods and systems for detecting the location of a sensor and determining calibration algorithms and/or coefficients for calculation of physiological parameters based on the detected location. An exemplary embodiment includes receiving a signal corresponding to absorption of at least one wavelength of light by a patient's tissue, generating a plethysmographic waveform from the signal, determining an identifying characteristic of the plethysmographic waveform, and determining a location of the sensor based on a comparison of the identifying characteristic with at least one defined criterion.
US08221310B2
Tissue visualization devices and variations thereof are described herein where such devices may utilize a variety of methods for facilitating clearing of the device of opaque bodily fluids and sealing between the device and the underlying tissue surface. Additionally, methods and devices for enhancing navigation of the device through a patient body are also described.
US08221301B2
Provided are a centrifuge that rotates about a rotation axis to separate a material and a method of centrifugal separation. The container is coupled to the centrifuge to freely pivot upward and downward on a pivoting axis vertical to a rotation plane. The container has an opening at an upper end thereof and holds a material inside. An angle adjuster raises the central axis of the container beyond a perpendicular angle with the rotation axis while the centrifuge is rotating in order to arrange the opening of the container downward with respect to the rotation plane and point an end of the container opposite to the opening of the container upward with respect to the rotation plane, and allow a portion of layers formed during centrifugal separating to flow down through the opening.
US08221298B2
Pre-stretched films may be used to increase the rate at which loads can be wrapped and to minimize the exertion required when using traditional handheld film. However, the edges of pre-stretched films are easily damaged, which may result in tearing or failure of the film during use. The present disclosure describes devices, systems, and methods for folding the edges of the film, resulting in a film that is less susceptible to damage and easier to use.
US08221295B2
An exercise device, comprising an upper body unit including at least one load member having at least one elastic/resilient element and a pair of gripping portions for manual grasping by the user, wherein an applied force exerted onto the gripping portions transitions the element from an initial state to an elastically deformed state, and wherein a reduction in the applied force resiliently reforms the element back toward the initial state. In one embodiment, a lower body unit is also provided including a support base defining a support surface, a plurality of light sources configured to generate discrete lighted regions on the support surface, and a controller configured to activate and deactivate the discrete lighted regions. In another embodiment, the lower body unit includes at least two position sensors having sensing paths arranged along a sensing plane to detect a presence of a user, and a controller in communication with the position sensors to determine a position of the user relative to the sensing plane.
US08221288B2
Various embodiments of methods, apparatus and systems that diagnose and/or detect faults of an electro-hydraulic control system for a transmission are presented. Some embodiments, adjust a main line pressure of the electro-hydraulic control system and detect faults based upon changes in a pressure switch resulting from such adjustments of the main line pressure. The pressure switch may be incorporated into a control main valve or a clutch trim valve of the electro-hydraulic control system.
US08221275B2
In a chain transmission using a hybrid chain having inner and outer links with bushings, or with bushings and rollers, the rollers mesh with a central sprocket, and the link plates have teeth that function as a silent chain, meshing with side sprockets fixed to the central sprocket. The teeth of the link plates of the inner links have a shape different from that of the teeth of the link plates of the outer links. The outer flanks of the teeth can all have the same shape, and the shape difference can be in the shapes of the inner flanks.
US08221260B2
Wood-type golf club heads include: (a) a club head body including heel, toe, crown, sole, and weighted rear portions; and (b) a variable thickness ball striking face. The club head body parts and weighted portion(s) may be arranged such that the club head has a moment of inertia about a vertical axis passing through the club head center of gravity of at least 5000 g-cm2. Such club heads may include: (a) a cup face member including a ball striking face portion and a return portion; (b) sole and crown portions engaged with the return portion; (c) a rear body member engaged with the crown and/or sole portions; (d) a weight member at the club head rear; and/or (e) a hosel member engaged with the cup face member, the crown portion, and/or the sole portion. Methods of making such club heads also are described.
US08221251B2
An articulated joint includes a first rotational member and a second rotational member coupled with and positioned generally coaxial to the first rotational member. The joint also includes a boot. The boot is selectively deformable in response to an increase in pressure in a joint chamber to increase the volume of the joint chamber. The volume of the joint chamber is selectively changed due to, at least in part, relative movement of the boot end to the second rotational member.
US08221238B1
A reputation of an on-line gamer is calculated in accordance with feedback about the gamer provided by other players. The gamer's reputation is determined in accordance with the number of players the gamer has encountered via game play, the number of players who have indicated that they prefer to play with the gamer again, and the number of players who have indicated that they prefer not to play with the gamer again. Parameters used to determine the gamer's reputation can be weighted and/or decayed to allow a more dynamic and temporally accurate determination of the gamer's reputation. Players can observe other players' reputations.
US08221235B2
The present invention provides a drawing machine and a game apparatus using the same by which it is easier to give the participants of the drawing an impression like drawing is carried out fairly when the computer drawing in which a winning-probability of each of drawing-objects is changed is carried out.A drawing machine for determining a winning-object from a plurality of drawing-objects includes: a winning-probability data storage unit for storing winning-probability data showing respective winning-probabilities of the plurality of drawing-objects; a drawing unit for carrying out a drawing in accordance with the winning-probability of each of the drawing-objects determined by the winning-probability data stored in the winning-probability data storage unit and determining a winning-object from the plurality of drawing-objects; a winning-probability data changing unit for changing the winning-probability data stored in the winning-probability data storage unit; a winning-probability image displaying unit for displaying a winning-probability image showing the winning-probability of each of the drawing-objects determined by the winning-probability data stored in the winning-probability data storage unit; and a winning-probability displaying control unit for changing the winning-probability image displayed on the winning-probability image displaying unit, when the winning-probability data changing unit changes the winning-probability data, so as to correspond to the changed winning-probability data.
US08221190B2
A polishing apparatus to simultaneously polish both surfaces of a work, and includes a pair of stools rotating in opposite directions, a pair of detecting units to detect rotation rates of the stools, a pressurizing unit to compress the work between the pair of the stools, a slurry supply unit to supply a slurry to the stools, and a control unit to reduce, when determining that a frictional force between the polishing surface and the work exceeds a threshold, at least one of a load applied by the pressurizing unit, the rotation rate of the stools, and a supply amount of the slurry.
US08221184B2
A floatable toy structure is disclosed herein, the floatable toy structure having: a floatable base portion; a collapsible track section secured to the floatable base portion, the collapsible track section capable of being positioned in an extended position and a stowed position, the collapsible track section extending upwardly from the floatable base portion when it is in the extended position; a support secured to the floatable base portion, the support configured to support the collapsible track section in the extended position; a pump for spraying water from a spray nozzle movably secured to the floatable toy structure; and a gate pivotally mounted to the floatable toy structure proximate to the collapsible track section, the gate being configured for movement between a first position and a second position, the gate further comprising a vessel for holding water therein, wherein the gate moves from the first position to the second position when a predetermined amount of water is placed into the vessel and wherein the gate moves away from the collapsible track section as it moves from the first position towards the second position.
US08221183B2
The present invention provides a versatile construction kit that can be used to easily form models of virtually any conceivable person, place or thing including a variety of vehicles, buildings, people, animals, weapons, machinery, caricatures, objects and the like. The construction kit comprises plural disc-shaped connectors that are connectable by way of a tongue-and-recessed retainer mechanism and optionally also by way of interconnectable notches by which they can be perpendicularly and detachably interconnected and/or optionally by way of a tongue-in-slot mechanism. The universal connectors are so versatile they can form virtually any geometric, regular, irregular, asymmetric, or symmetric configuration.
US08221179B2
The cavity 102 defines an empty volume formed in the insulator 108 has its walls defined by the insulator 108 and may extend through either (or both) the first electrode 106 or the second electrode 104, in which case the first electrode and/or second electrode also define the walls of the cavity 102. The cavity 102 is preferably cylindrical and has a diameter of 0.1 μm-1 mm. More preferably, the diameter ranges from 0.1 μm-500 μm, 1 μm-100 μm, or 100 μm-500 μm. The cavity 102 will be filled with a gas that contacts the cavity walls, fills the entire cavity 102 and is selected for its breakdown voltage or light emission properties at breakdown. Light is produced when the voltage difference between the first electrode 106 and the second electrode 104 creates an electric field sufficiently large to electrically break down the gas (nominally about 104 V-cm). This light escapes from the microcavity 102 through at least one end of the cavity 102.
US08221178B2
An organic electro-luminescence display device includes a thin film transistor on a first substrate, where the thin film transistor has a drain region and a common electrode connected to the drain region. An organic electro-luminescence diode resides on a second substrate, where the organic electro-luminescence diode includes a spacer covered with a diode electrode. First and second sealant materials reside at a periphery of the first and second substrates, where the first sealant material surrounds the thin film transistor and the organic electro-luminescence diode, and the second sealant material surrounds an outer perimeter of the first sealant material. The first and second substrates are bonded together, such that the common electrode of the thin film transistor contacts the diode electrode of the organic electro-luminescence diode. The bonding process is carried out by sequentially sealing the first sealant material and the second sealant material.
US08221170B2
An electrical connector includes an insulative housing defining a base and a cover confronting with the base, and a plurality of contacts sandwiched between the base and the cover. The base defining at least one latching post to engaging with corresponding mating hole on the cover. The at least one post is a cone tubular with a diameter of a free end thereof larger than a diameter of a root thereof and the mating hole has a portion aligned with the free end which has a larger diameter than another portion thereof aligned with the root.
US08221168B2
A plug connector for a cable having at least two signal conductors, in particular a star quad cable, having a signal conductor part and an insulating part which holds the signal conductor part. The signal conductor part has a spring lug, electrically and mechanically connected to a signal conductor, wherein the insulating part has an axial hole and a spring lug passes through each of said axial holes, wherein the holes are arranged to hold the spring lugs at a physical distance from one another. The spring lugs project beyond the insulating part at the plugging-side end and are bent over in such a way that the respective bent-over portions of the spring lugs run from the plugging-side end in the direction of the cable-side end on an outer face of the insulating part and can be resiliently elastically deformed in the radial direction.
US08221163B2
The invention provides a connector including a body having an insulating property; a terminal group provided in the body; and a shield case having electrical conductivity. The terminal group includes a first terminal, and a second terminal, being provided adjacent to the first terminal and having higher impedance than the first terminal. The shield case includes an outer shell, configured to surround an peripheral surface of the body, and an impedance adjuster, provided at the outer shell and located adjacent to at least a portion of the second terminal and on an opposite side of the second terminal from the first terminal.
US08221159B2
A patchbay includes a front panel, a rear panel, and a circuit board with conducting traces. The front panel has mounted thereon a plurality of XLR/TRS combination jacks, and sets of pairs of TRS jacks. The rear panel has five DB25 connectors. The circuit board extends from the front panel to the rear panel; each set of three conducting traces forms a channel connected to one of the DB25 connectors. The DB25 connectors connect to channels for Mic in, Line in, Preamp out, A/D in, and D/A out, respectively. Each XLR/TRS combination jack is connected to a Mic in channel and to a Line in channel. One of each pair of TRS jacks in the first set is connected to a Preamp out channel and the other is connected to an A/D in channel. Each TRS jack in the second set is connected to a D/A out channel.
US08221158B2
A socket having a replaceable module includes a socket panel and a replaceable module. The socket panel is provided with socket units. The replaceable module is detachably provided on the socket panel. The replaceable module is provided with socket subunits. The edge of the replaceable module is provided with a trough located between the replaceable module and the socket panel. The present invention further provides a replaceable module for a socket. The replaceable module can be replaced according practical demands, which makes it more versatile. Further, the replaceable module has a better safety.
US08221155B2
The present invention relates to a splice restraint for use with sleeves that attach to joints. The splice restraint includes a first securing member constructed and arranged to be received in a groove of a first sleeve that is installable on a first leg of a joint, a second securing member constructed and arranged to be received in a groove of a second sleeve that is installable on a second leg of the joint, and a strap connecting the first securing member to the second securing member. The strap having a length determined by the distance between the groove on the first sleeve and the groove on the second sleeve when the first and second sleeves are properly installed on the joint. The splice restraint provides a visual indication that the sleeves are properly installed on the joint, as well ensures that sleeves will not be displaced after the lineman leaves the site.
US08221137B2
A mini display port structure is provided for receiving a connector insert. The mini display port structure includes a circuit board unit and a receptacle unit. The circuit board unit has a base board, wherein an opening is formed on one side of the base board. A portion of the receptacle unit is accommodated in the opening of the circuit board unit and is connected to the base board. Accordingly, the circuit board unit is elevated at a certain position within the height of receptacle unit, and thus the height of the receptacle unit can include the height of the circuit board unit at the same time, thereby shrinking the height of the mini display port structure after the circuit board unit is assembled for making a compact mini display port.
US08221118B2
Dental retention systems which facilitate the adjustment or removal of an oral appliance, e.g., a crown or bridge, from a reconfigurable abutment assembly are described. The adjustable abutment assembly may be secured to an anchoring implant bored into the bones within the mouth. The abutment assembly has a projecting abutment portion with one or more shape memory alloy compression plates or elements extending along the projecting abutment portion. Each of the plates has a length with one or more straightened portions and with at least one curved or arcuate portion. Energy may be applied to the elements such that the arcuate portion self-flattens to allow for the oral appliance to be placed thereupon while removal of the energy allows the elements to reconfigure into its curved configuration thereby locking the oral appliance to the abutment. Removal of the oral appliance may be effected by reapplication of energy to the elements.
US08221115B2
A system includes a first source containing a liquid fuel, a second source containing a gaseous fuel, and a combustion burner connected to the first and second sources and selectively in fluid communication with the liquid fuel and the gaseous fuel to receive the fuels. The burner is capable of switching between combustion of the liquid fuel and combustion of the gaseous fuel without modification to the burner or the system.
US08221114B2
A mold for fabricating an optical fiber connector is provided. The mold includes a mold body, a core pin and a positioning block. The mold body defines a molding chamber, and the molding chamber has a lens forming portion for forming a lens. The core pin is configured for insertion into the molding chamber and forming an optical fiber insertion hole. The core pin includes a first portion and a second portion thinner than the first portion. The positioning block is configured for being arranged in the molding chamber. The positioning block includes an engaging hole for engagingly receiving the second portion.
US08221112B2
A method of securely mounting a stent on a balloon of a catheter. The method generally includes crimping a stent on a balloon of a catheter at least one time, and positioning the balloon with the stent thereon within a polished bore of a mold formed at least in part of a metallic material. The balloon is pressurized and heated within the mold, or within a sheath, in two stages as the stent is restrained from radially expanding. The method may include crimping the stent onto the balloon one or two times during processing. The method increases retention of the stent on the balloon catheter following sterilization.
US08221111B2
Disclosed is a mold wherein one bottom surface member (2) and four lateral surface members (3) are assembled. The sides of each lateral surface member (3) are respectively provided with a projection (5) and a recess (6) for combining the lateral surface members together, and the projection (5) of one lateral surface member (3) is engaged with the recess (6) of the adjacent lateral surface member (3). By using the one bottom surface member (2) and four lateral surface members (3), a mold can be assembled or disassembled without using screw or bolts. Consequently, the assembly or disassembly work of the mold is dramatically simplified, thereby improving work efficiency significantly.
US08221108B2
A punch (10, 110) for forming a tablet is described. The punch includes a cam surface (24, 124) which in use contacts a compression surface (62). The cam surface includes a substantially planar flat portion (14, 114), the flat portion having a non-circular shape when viewed along a direction (20) normal to the plane of the flat portion.
US08221107B2
The invention relates to a mold clamping unit on a plastic injection molding machine, the unit having a clamping mechanism for opening and closing an injection mold, the mechanism having a servo motor as the drive motor (21). The drive motor drives at least one spindle drive (10) which has a spindle nut (12) and spindle which work together on a bearing position (14). A cooling system with cooling channels (25) is provided for removing heat from the clamping mechanism. A more efficient cooling of the spindle drive is achieved in that the cooling channels (25) penetrate the bearing position (14) of the spindle drive (10) and/or one of the cooling plates (23) assigned to the bearing position.
US08221103B2
A motor, comprising: an internal motor chamber, and a rotor rotatable therein. The rotor is drivable by having a pressure medium applied to it and a braking element for braking the rotor. The braking element is axially arranged directly adjacent to the rotor, wherein the braking element and the rotor are axially moveable with respect to each other and form a spring-loaded friction pair, at least between a front end face of the rotor and the braking element.
US08221102B2
A hydraulic machine has a gear wheel (2) with outwardly extending teeth and a gear ring (4) with inwardly extending teeth formed by rollers each of which is supported in a pocket (8) in the gear ring, and pressurized spaces are formed between the gear wheel and the inwardly extending teeth. To keep the wear of the machine small, each pocket (8) has at least two different radii (R1, R2, Rn) whereby a radius (R2, Rn) at a smaller displacement from the edge (12) of the pocket is larger than a radius (R1) at a larger displacement from the same edge (12) of the pocket (8).
US08221100B2
A valve seat for use in a high pressure pump comprises an inner portion force fit within an outer portion. The outer portion has a fluid plenum at an outer peripheral surface. Fluid passages extend radially inwardly to communicate with a valve recess in the inner portion. A seal housing for a high pressure pump comprises an outer portion and an inner portion. The inner portion is force fit within the outer portion. The inner portion has an inner bore having a first location to receive seal packings, and a second location to receive valve spring structure. The inner portion has a curved surface that bottoms out against a curved surface within the outer portion.
US08221099B2
A fluid pump assembly is disclosed for performing in a damp environment. A pump member is provided that drives a quantity of fluid. A pump housing encloses the pump member and includes a breather hole for circulating cooling air around the pump member during operation. A cover is provided that substantially covers the breather hole and defines a tortuous path that enables air to circulate through the breather hole while preventing entry of water thereto.
US08221082B2
An impeller is provided having a first plate, a second plate, a plurality of blades being positioned between and connected to the first and second plates, and at least one brace member having first and second planes positioned between and connected to two blades such that the brace extends generally perpendicular from the first blade and extends from the second blade at an angle.
US08221078B2
Power and signals may be transmitted from a root portion of an extendable rotor blade to a moving tip portion using a slide block and a slide channel. The slide block is configured to fit within the slide channel and includes a conductive element that comes into contact with a conductive element of the slide channel. The tip portion may be attached to the slide block such that as the slide block moves along the slide channel, the tip portion is extended or retracted accordingly. The conductive elements may be fixed within each of the slide block and slide channel so that when the tip portion is retracted or extended, the conductive elements do not move.
US08221077B2
A fan blade assembly having both an electrical connection and a mechanical connection to a rotating hub. The assembly is configured so that a single installation motion creates the mechanical connection and the electrical connection. The electrical connection preferably includes multiple independent conductor paths.
US08221075B2
A method for operating a wind turbine includes operatively coupling a fluid container within the wind turbine. The fluid container is in flow communication with an air distribution system at least partially defined within a blade of the wind turbine. The method further includes channeling a fluid from the fluid container into the air distribution system, and discharging the fluid from the air distribution system through at least one aperture of the air distribution system defined through an outer surface of the blade to facilitate removing debris from the air distribution system.
US08221074B2
A shroud assembly for an engine cooling fan positioned between an engine and a radiator includes a ring shroud, a radiator shroud, and a flexible boot. The ring shroud is mounted adjacent to the fan and includes a locking feature. The radiator shroud, which is mounted to the rear of the radiator, has a first end with a first aperture for receiving air flowing rearwardly through the radiator, and a second end with a second aperture for discharging air received by the first aperture. A first end of the flexible boot engages the locking feature of the ring shroud to secure the flexible boot to the ring shroud. A second end of the flexible boot contacts the radiator shroud so that the boot provides fluid communication between the ring shroud and the radiator shroud.