US08766411B2
A filler for filling a gap includes a compound represented by the following Chemical Formula 1. SiaNbOcHd. [Chemical Formula 1] In Chemical Formula 1, a, b, c, and d represent relative amounts of Si, N, 0, and H, respectively, in the compound, 1.96
US08766408B2
A packaged semiconductor device is manufactured by a simplified manufacturing process, and is reduced in cost, in thickness and in size. A device component and a pad electrode connected with the device component are formed on a semiconductor substrate. A supporter is bonded to a top surface of the semiconductor substrate through an adhesive layer. Then, there is formed a protection layer that has an opening at a location corresponding to the pad electrode and covers a side surface and a back surface of the semiconductor substrate. A conductive terminal is formed on the pad electrode at the location corresponding to the opening formed in the protection layer. No wiring layer or conductive terminal is formed on the back surface of the semiconductor substrate. A conductive terminal is formed on a periphery of the supporter outside of and next to the side surface of the semiconductor substrate.
US08766400B2
An electronic device and fabrication method thereof are provided. The electronic device contains a glass substrate, a patterned semiconductor substrate, having at least one opening, disposed on the glass substrate and at least one passive component having a first conductive layer and a second conductive layer, wherein the first conductive layer is disposed between the patterned semiconductor substrate and the glass substrate.
US08766398B2
A discrete semiconductor device has a substrate with a first conductivity type of semiconductor material. A first semiconductor layer is formed over the substrate. The first semiconductor layer having the first conductivity type of semiconductor material. A second semiconductor layer over the first semiconductor layer. The second semiconductor layer has a second conductivity type of semiconductor material. A trench is formed through the second semiconductor layer and extends into the second semiconductor layer. The trench has a rounded or polygonal shape and vertical sidewalls. The trench is lined with an insulating layer and filled with an insulating material. A boundary between the first and second semiconductor layers forms a p-n junction. The trench surrounds the p-n junction to terminate the electric field of a voltage imposed on the second semiconductor layer. The discrete semiconductor device can also be a transistor, thyristor, triac, or transient voltage suppressor.
US08766388B2
A polymerizable composition contains (A) a polymerization initiator that is an acetophenone-based compound or an acylphosphine oxide-based compound, (B) a polymerizable compound, (C) at least either a tungsten compound or a metal boride, and (D) an alkali-soluble binder.
US08766380B2
A method of forming a MEMS device by encapsulating a MEMS element with a sacrificial layer portion deposited over a substrate arrangement, the portion defining a cavity for the MEMS element, forming at least one strip of a further sacrificial material extending outwardly from the portion, forming a cover layer portion over the sacrificial layer portion, the cover layer portion terminating on the at least one strip, removing the sacrificial layer portion and the at least one strip, the removal of the at least one strip defining at least one vent channel extending laterally underneath the cover layer portion and sealing the at least one vent channel. A device including such a packaged micro electro-mechanical structure.
US08766377B2
A method of forming a back gate transistor device includes forming an open isolation trench in a substrate; forming sidewall spacers in the open isolation trench; and using the open isolation trench to perform a doping operation so as to define a doped well region below a bottom surface of the isolation trench that serves as a back gate conductor, wherein the sidewall spacers prevent contamination of a channel region of the back gate transistor device by dopants.
US08766359B2
An integrated circuit containing an extended drain MOS transistor with deep semiconductor (SC) RESURF trenches in the drift region, in which each deep SC RESURF trench has a semiconductor RESURF layer at a sidewall of the trench contacting the drift region. The semiconductor RESURF layer has an opposite conductivity type from the drift region. The deep SC RESURF trenches have depth:width ratios of at least 5:1, and do not extend through a bottom surface of the drift region. A process of forming an integrated circuit with deep SC RESURF trenches in the drift region by etching undersized trenches and counterdoping the sidewall region to form the semiconductor RESURF layer. A process of forming an integrated circuit with deep SC RESURF trenches in the drift region by etching trenches and growing an epitaxial layer on the sidewall region to form the semiconductor RESURF layer.
US08766356B2
A semiconductor device capable of reducing a thickness, an electronic product employing the same, and a method of fabricating the same are provided. The method of fabricating a semiconductor device includes preparing a semiconductor substrate having first and second active regions. A first transistor in the first active region includes a first gate pattern and first impurity regions. A second transistor the second active region includes a second gate pattern and second impurity regions. A first conductive pattern is on the first transistor, wherein at least a part of the first conductive pattern is disposed at a same distance from an upper surface of the semiconductor substrate as at least a part of the second gate pattern. The first conductive pattern may be formed on the first transistor while the second transistor is formed.
US08766355B2
A semiconductor device includes a device isolation pattern in which a polysilicon layer pattern doped with oxygen, carbon or nitrogen is interposed between an inner wall of a trench and a nitride liner. The semiconductor device includes a semiconductor substrate including a trench, a polysilicon layer pattern on a surface of the trench, a nitride layer pattern on the polysilicon layer pattern, and an insulation layer pattern on the nitride layer pattern and filling the trench. The polysilicon layer pattern may be doped with oxygen, carbon and/or nitrogen. Related manufacturing methods are also disclosed.
US08766354B2
A semiconductor device including a plurality of buried word lines extending in a first direction and a plurality of buried bit lines extending in a second direction. Upper surfaces of the plurality of buried word lines and the plurality of buried bit lines are lower than an upper surface of a substrate. The distance between two active regions that constitute a pair of first active regions from among a plurality of first active regions included in a first group of active regions is less than the distance between two adjacent active regions having the plurality of buried bit lines therebetween. A method of manufacturing a semiconductor device includes forming a plurality of first trenches in a substrate, forming a plurality of first conductive patterns in the plurality of first trenches in such a manner that a pair of first conductive patterns is disposed in each of the plurality of first trenches, forming a plurality of first buried patterns in the plurality of first trenches to cover the plurality of first conductive patterns, forming a plurality of second trenches by etching the substrate between the plurality of first trenches, and forming a plurality of second buried patterns in the plurality of second trenches.
US08766349B2
The present invention relates to a semiconductor device, a memory array and a fabrication method thereof, and more particularly to a semiconductor device having a stacked array structure (referred to as a STAR structure: a STacked ARray structure) applicable to not only a switch device but also a memory device, a NAND flash memory array using the same as a memory device and a fabrication method thereof.
US08766342B2
Methods and an apparatus are described for an integrated circuit within which an electroless Cu plated layer having an oxygen content is formed on the top of a seed layer comprising Cu and Mn. The integrated circuit is then exposed to a sufficient high temperature to cause the self-formation of a MnSiOx barrier layer.
US08766337B2
A first thin film diode (100A) has a first semiconductor layer (10A) and a first light blocking layer (12A) disposed on the substrate side of the first semiconductor layer. A second thin film diode (100B) has a second semiconductor layer (10B) and a second light blocking layer (12B) disposed on the substrate side of the second semiconductor layer. An insulating film (14) is formed between the first semiconductor layer (10A) and the first light blocking layer (12A) and between the second semiconductor layer (10B) and the second light blocking layer (12B). A thickness D1 of a portion of the insulating film (14) positioned between the first semiconductor layer (10A) and the first light blocking layer (12A) is different from a thickness D2 of a portion of the insulating film (14) positioned between the second semiconductor layer (10B) and the second light blocking layer (12B). The intensity of light in a first wavelength region incident on the first semiconductor layer (10A) is higher than the intensity of light in the first wavelength region incident on the second semiconductor layer (10B). The intensity of light in a second wavelength region including a wavelength longer than the maximum wavelength of the first wavelength region incident on the second semiconductor layer (10B) is higher than the intensity of light in the second wavelength region incident on the first semiconductor layer (10A).
US08766323B2
An organic light emitting display apparatus and method of manufacturing the organic light emitting display apparatus including a lower substrate having power lines in a non-display region that is outside a display region whereon an image is realized; and a functional layer formed between the power lines and an encapsulation substrate.
US08766317B2
Provided is a semiconductor device in which on-resistance is largely reduced based on a new principle of operation. In the semiconductor device, if an embedded electrode is at negative potential, a depletion layer is formed from a trench to a neighboring trench so that a channel is turned off. If the embedded electrode is at a positive potential, the depletion layer is not formed in every region between the neighboring trenches so that the channel is turned on.
US08766314B2
An object is to provide a light-emitting device having a structure in which an external connection portion can easily be connected and a method for manufacturing the light-emitting device. A light-emitting device includes a lower support 110, a base insulating film 112 over the lower support 110 which has a through-hole 130, a light-emitting element 127 over the base insulating film 112, and an upper support 122 over the light-emitting element 127. An electrode 131 is provided in the through-hole 130, and the external connection terminal 132 electrically connected to the electrode 131 is provided below the base insulating film 112. The external connection terminal 132 is electrically connected to the external connection portion 133 and functions as a terminal that inputs a signal or a power supply into the light-emitting device. This light-emitting device has a structure in which an external connection portion can easily be connected.
US08766303B2
A light-emitting diode (LED) with a mirror protection layer includes sequentially stacked an N-type electrode, an N-type semiconductor layer, a light-emitting layer, a P-type semiconductor layer, a metal mirror layer, a protection layer, a buffer layer, a binding layer, a permanent substrate, and a P-type electrode. The protection layer is made of metal oxide, and has a hollow frame for covering or supporting edges of the metal mirror layer.
US08766297B2
According to one embodiment, a semiconductor light emitting device includes a stacked structural body, first and second electrodes, a high resistance layer and a transparent conductive layer. The stacked structural body includes first and second semiconductor layers and a light emitting layer. The first semiconductor layer is disposed between the first electrode and the second semiconductor layer. The second semiconductor layer is disposed between the second electrode and the first semiconductor layer. The second electrode has reflectivity with respect to luminescent light. The high resistance layer is in contact with the second semiconductor layer between the second semiconductor layer and the second electrode and includes a portion overlapping with the first electrode. The transparent conductive layer is in contact with the second semiconductor layer between the second semiconductor layer and the second electrode. The transparent conductive layer has a resistance lower than a resistance of the high resistance layer.
US08766296B2
A gallium nitride (GaN) based light emitting diode (LED), wherein light is extracted through a nitrogen face (N-face) of the LED and a surface of the N-face is roughened into one or more hexagonal shaped cones. The roughened surface reduces light reflections occurring repeatedly inside the LED, and thus extracts more light out of the LED. The surface of the N-face is roughened by an anisotropic etching, which may comprise a dry etching or a photo-enhanced chemical (PEC) etching.
US08766295B2
A semiconductor device includes a first light emitting chip, the first light emitting chip having a first semiconductor layer, a second semiconductor layer, and a first active layer disposed therebetween, a second light emitting chip disposed on the first light emitting chip, the second light emitting chip having a third semiconductor layer, a fourth semiconductor layer, and a second active layer disposed therebetween, and a conductive layer disposed between the first semiconductor layer and the fourth semiconductor layer, the first semiconductor layer and the fourth semiconductor layer having different conductivity types.
US08766286B2
An organic opto-electric device has a layer stack with a base electrode, an organic layer assembly, a cover electrode and a contact layer. The organic layer assembly is arranged between the base electrode and the cover electrode and the cover electrode is arranged between the organic layer assembly and the contact layer. The cover electrode and the base electrode are structured to form several laterally adjacent optically active areas and the base electrode, the organic layer assembly, the cover electrode and the contact layer are interconnected by vias such that at least two optically active areas are connected in series so that a current flow through the at least two optically active areas passes in a direction between the base electrode and a cover electrode. The current flow between the at least two optically active areas passes through the contact layer, wherein the contact layer contacts the base electrode above one of the vias laterally in the interior of the two optically active areas.
US08766283B2
The invention relates to a light-emitting arrangement, having:—at least one light-emitting diode chip (1),—a multi-layer board (17) having a base (5) of a thermally well conducting material, in particular of metal, and—an electrical insulating and thermally conducting connection layer (2) between the emission surface of the light-diode chip (1) and the board (17).
US08766274B2
Disclosed are methods and materials useful in the preparation of semiconductor devices. In particular embodiments, disclosed are methods for engineering polycrystalline aluminum nitride substrates that are thermally matched to further materials that can be combined therewith. For example, the polycrystalline aluminum nitride substrates can be engineered to have a coefficient of thermal expansion (CTE) that is closely matched to the CTE of a semiconductor material and/or to a material that can be used as a growth substrate for a semiconductor material. The invention also encompasses devices incorporating such thermally engineered substrates and semiconductor materials grown using such thermally engineered substrates. The thermally engineered substrates are advantageous for overcoming problems caused by damage arising from CTE mismatch between component layers in semiconductor preparation methods and materials.
US08766266B2
A semiconductor substrate includes: a thin-film transistor including an organic semiconductor layer; and a light absorption-transmission layer provided in a pathway that leads external light to the organic semiconductor layer. The light absorption-transmission layer absorbs light of a wavelength range that includes at least a part of a light absorption wavelength range of the organic semiconductor layer, and allows light of a remaining wavelength range to pass therethrough.
US08766265B2
An OLED device includes: a TFT including an active layer, gate, source and drain electrodes, a first insulating layer between the active layer and the gate electrode, and a second insulating layer between the source and drain electrodes, a pixel electrode on the first and second insulating layers, connected to one of the source and drain electrodes, a capacitor including a first electrode on the same layer as the active layer, a second electrode on the same layer as the gate electrode, and a third electrode formed of the same material as the pixel electrode, a third insulating layer between the second insulating layer and the pixel electrode and between the second and third electrodes, a fourth insulating layer covering the source, drain and third electrodes, exposing a portion of the pixel electrode, an organic light-emitting layer on the pixel electrode, and a counter electrode on the organic light-emitting layer.
US08766253B2
To provide a semiconductor device including a transistor formed using a highly reliable oxide semiconductor. To provide a semiconductor device which can be manufactured with high productivity and high yield by reducing the number of photolithography steps. The semiconductor device includes a first wiring, a second wiring, and a third wiring whose potential is lower than those of the first wiring and the second wiring between the first wiring and the second wiring. In the semiconductor device, the first wiring is electrically connected to the third wiring through a first transistor in which a gate electrode layer is electrically connected to a source electrode layer, the second wiring is electrically connected to the third wiring through a second transistor in which the gate electrode layer is electrically connected to the source electrode layer, and a continuous oxide semiconductor film used for a semiconductor region of the first transistor and the second transistor is provided above or below the first wiring, the second wiring, and the third wiring.
US08766249B2
Provided are a novel nitrogen-containing aromatic heterocyclic compound and an organic electronic device using the compound. This nitrogen-containing aromatic compound is represented by the general formula (1). Further, the present invention relates to organic electronic devices such as a light-emitting device, a thin-film transistor, and a photovoltaic device each using the nitrogen-containing aromatic compound. (L represents an m+n-valent aromatic hydrocarbon group or aromatic heterocyclic group, or a group arising from a triarylamine or a diaryl sulfone; X represents N-A, O, S, or Se; A represents an alkyl group or the like; R represent hydrogen, an alkyl group, an aromatic group, or the like; and m+n is an integer of 2 to 4.)
US08766247B2
An organic light emitting device includes a substrate divided into and defined by first to third pixels, a first electrode disposed on the substrate and a second electrode facing the first electrode, a first light emitting layer and a second light emitting layer disposed in the first pixel and in the second pixel, respectively, between the first electrode and the second electrode, a first triplet exciton confinement layer, a third light emitting layer and a second triplet exciton confinement layer disposed over the first to third pixels in this order, on the first light emitting layer and the second light emitting layer, and a first common layer disposed between the first light emitting layer and the second light emitting layer, and the first electrode, and a second common layer disposed between the second triplet exciton confinement layer and the second electrode.
US08766240B2
A permeation barrier film structure for organic electronic devices includes one or more bilayers having a hybrid permeation barrier composition. Each of the one or more bilayers includes a first region having a first composition corresponding to a first CF4—O2 Plasma Reactive Ion Etch Rate and a second region having a second composition corresponding to a second CF4—O2 Plasma Reactive Ion Etch Rate, wherein the second Etch Rate is greater than the first Etch Rate by a factor greater than 1.2 and the hybrid permeation barrier film is a homogeneous mixture of a polymeric material and a non-polymeric material, wherein the mixture is created from a single precursor material.
US08766238B2
The present invention relates to light-emitting devices and in particular organic light-emitting devices (OLEDs). In particular, the invention relates to emitter materials in which charged metal complexes are bonded to a polymer by electrostatic interactions.
US08766235B2
Some embodiments include methods of forming BJTs. A first type doped region is formed within semiconductor material. First and second trenches are formed within the semiconductor material to pattern an array of pedestals, and the trenches are filled with electrically insulative material. An upper portion of the first type doped region is counter-doped to form a first stack having a second type doped region over a first type doped region, and an upper portion of the first stack is then counter-doped to form a second stack having a second type doped region between a pair of first type doped regions. Some embodiments include a BJT array. A base implant region is between a pair of emitter/collector implant regions. Electrically insulative material is adjacent the base implant region, and contains at least about 7×1016 atoms/cm3 of base implant region dopant.
US08766234B1
Selector devices that can be suitable for memory device applications can have low leakage currents at low voltages to reduce sneak current paths for non selected devices, and high leakage currents at high voltages to minimize voltage drops during device switching. In some embodiments, the selector device can include a first electrode, a tri-layer dielectric layer, and a second electrode. The tri-layer dielectric layer can include a high leakage dielectric layer sandwiched between two lower leakage dielectric layers. The low leakage layers can function to restrict the current flow across the selector device at low voltages. The high leakage dielectric layer can function to enhance the current flow across the selector device at high voltages.
US08766232B2
According to a method of fabricating the semiconductor memory device, a contact plug can be protected while mold openings are formed. A semiconductor memory device may include a mold dielectric layer on an entire surface of a substrate, the substrate including a first region and a second region. A contact plug may be provided in a contact hole formed through the mold dielectric layer in the first region. A variable resistor may be provided in a mold opening formed through the mold dielectric layer in the second region. An upper surface of the contact plug may be at a level equal to or lower than an upper surface of the mold dielectric layer.
US08766231B2
On example of the present invention is a nanoscale electronic device comprising a first conductive electrode, a second conductive electrode, and a device layer. The device layer comprises a first dielectric material, between the first and second conductive electrodes, that includes an effective device layer, a first barrier layer near a first interface between the first conductive electrode and the device layer, and a second barrier layer near a second interface between the second conductive electrode and the device layer. A second example of the present invention is an integrated circuit that incorporates nanoscale electronic devices of the first example.
US08766224B2
An electrically actuated switch comprises a first electrode, a second electrode, and an active region disposed therebetween. The active region comprises at least one primary active region comprising at least one material that can be doped or undoped to change its electrical conductivity, and a secondary active region comprising at least one material for providing a source/sink of ionic species that act as dopants for the primary active region(s). Methods of operating the switch are also provided.
US08766223B2
A packaging machine and a device for monitoring a roll with film material wound thereon is disclosed. By means of a sensor arrangement, an end of the film material on the roll may be detected. The sensor arrangement includes at least one optoelectric sensor arranged stationary relative to a front side of the roll. The optoelectric sensor is designed such that a portion of an outer circumference of the rotating roll may be detected.
US08766220B2
A charged particle beam irradiation apparatus includes: an irradiation section configured to irradiate an irradiated body with a charged particle beam; a multi-leaf collimator configured to set an irradiation range of the charged particle beam which is irradiated from the irradiation section; an imaging section that is provided so as to be able to advance and retreat with respect to an irradiation axis of the charged particle beam which is irradiated from the irradiation section, between the irradiation section and the multi-leaf collimator, and directly images an opening portion of the multi-leaf collimator; and a drive section configured to move the imaging section between an imaging position corresponding to an irradiation area which includes the irradiation axis of the charged particle beam and a retreated position away from the irradiation area.
US08766219B2
A method of operating a particle beam microscopy. A particle beam is scanned across a scanning region of a surface of the object. Particles are detected by a detector system for a plurality of impingement locations of the primary beam within the scanning region. A detector system generates detector signals which represent for each of the impingement locations an intensity of the detected particles. Material data of the interaction regions are calculated depending on the detector signals and depending on topography data, which represent a topography of the object surface in the scanning region.
US08766215B2
A charged particle beam drawing apparatus includes: a charged particle optical system; a substrate stage; an interferometer configured to measure a position of the stage in the direction of the optical axis of the charged particle optical system; a measuring device configured to measure a characteristic of the charged particle beam; and a controller configured to correct the measurement, obtained by the interferometer, using correction information. The controller is configured to cause first measurement as measurement by the interferometer and second measurement as measurement by the measuring device to be performed in parallel, and to obtain the correction information based on the first measurement and the second measurement obtained with respect to each of the plurality of positions.
US08766211B2
There is described a fluid treatment system in which fluid to be treated is impinged under pressure on a radiation emitting surface. The fluid treatment system includes at least one radiation source having a radiation emitting surface and at least one nozzle element having a fluid discharge opening spaced from the radiation emitting surface. The fluid discharge opening is configured to impinge fluid to be treated on to at least a portion of the radiation emitting surface. The fluid treatment system is well suited to treating low transmittance fluid.
US08766210B2
Charged particle system are disclosed and include a first voltage source, a second voltage source electrically isolated from the first voltage source, a charged particle source electrically connected to the first voltage source, and an extractor electrically connected to the second voltage source. Methods relating to the charged particle systems are also disclosed.
US08766203B2
A solid state imaging device 1 includes a photodetecting section 10, a signal readout section 20, a controlling section 30, dummy photodetecting sections 11 and 12 including dummy photodiodes, discharging arrangement for discharging junction capacitance portions of the dummy photodiodes, and a scintillator layer 50 provided so as to cover the photodetecting section 10. The dummy photodetecting section 11 is disposed so as to neighbor the first row (the upper side of the photodetecting section 10) of the photodetecting section 10 and has a length equivalent to the length of the photodetecting section 10 in the left-right direction. The dummy photodetecting section 12 is disposed so as to neighbor the M-th column of the photodetecting section 10 (the lower side of the photodetecting section 10) and has a length equivalent to the length of the photodetecting section 10 in the left-right direction.
US08766190B2
Disclosed are a pixel, a pixel array, an image sensor including the same, and a method for operating the image sensor. Charges are eliminated from a first photoelectric conversion region of a photoelectric conversion section, and accumulated into the first photoelectric conversion region. Information about quantity of the charges of the first photoelectric conversion region is output, and charges are removed from a second photoelectric conversion region of the photoelectric conversion section. Accumulation of charges into the second photoelectric conversion region is started, and then information about quantity of the charges accumulated in the second photoelectric conversion region is output.Lights having wavelength bands different from each other are independently detected according to disclosed invention.
US08766187B2
A pyroelectric sensor array is attachable on a circuit board. The pyroelectric sensor array comprises a pyroelectric board and a plurality of pyroelectric elements formed on the pyroelectric board. The pyroelectric board has a connection surface configured to be placed on the circuit board. The pyroelectric elements contains a peripheral pyroelectric element arranged at a peripheral portion of the pyroelectric board in a predetermined arranging direction and a central pyroelectric element arranged at a central portion of the pyroelectric board. Each of the pyroelectric elements has two adjacent connection electrodes formed on the connection surface. An electrostatic capacity between the two connection electrodes of the peripheral pyroelectric element is larger than an electrostatic capacity between the two connection electrodes of the central pyroelectric element.
US08766185B2
The charged particle beam device has an unlimitedly rotatable sample stage and an electric field control electrode for correcting electric field distortion at a sample peripheral part. A voltage is applied to a sample on the unlimitedly rotatable sample stage through a retarding electrode that is in contact with a holder receiver at a rotation center of a rotary stage. An equipotential plane on the electric field control electrode is varied by applying a voltage to the electric field control electrode, and following this the equipotential plane at a sample edge is corrected, which enables the sample to be observed as far as its edge.
US08766184B2
With a scanning electron microscope (SEM) adopting a commonly available exhaust system such as a turbo-molecular pump, an ion pump, or a rotary pump, and so forth, there is realized an apparatus capable of safely executing observation, or adsorption of a target substance that is high in rarity. Further, there is realized a safe SEM low in the risk of an electrical discharge by providing the apparatus with a probe, a means for replacing an atmosphere in a specimen chamber, with a predetermined gas, and a means for forming an image by detection of an ion current, and detection of an absorption current. Further, there is provided a means for controlling the polarity of a voltage applied to the probe. Still further, there is provided a control means for controlling a value of the voltage applied to the probe according to a degree of vacuum.
US08766181B2
An optical system includes a beam splitter disposed along an optical axis and a set of mirrors optically coupled to the beam splitter. The set of mirrors are oriented perpendicular to each other. The optical system also includes a turning mirror optically coupled to a second mirror of the set of mirrors and a detector optically coupled to the turning mirror.
US08766177B2
A coupled nanomanipulation and nanospray mass spectrometry (NMS) system for single cell, single organelle, and ultra-trace molecular analysis is disclosed herein. The system primarily comprises a bio-workstation coupled to a NMS. The bio-workstation primarily comprises of a nanomanipulator stage with a plurality of nano-positioners attached to a cabinet with a piezo voltage source and a pressure injector. The present invention further describes a fingerprint lift method that when coupled with the system disclosed herein can be used for retrieval and analysis of trace amounts of drug and explosive residues. The system described herein has been used in the areas of trace and document analysis within the forensic field, trace fiber analysis, and electrostatic lifts for illicit drugs, as well as document and painting analysis.
US08766168B2
A sensor of the type for liquid and/or gas analysis, which is connected to a measuring and/or evaluating system or, respectively, to a higher-ranking control system and has a sensor housing. The circuit for the collecting, processing and transmitting measured values to the measuring and/or evaluating system or to the control system (19) are provided in the sensor housing (2). This circuit has analog sensor electronics (3), an analog-digital converter (14) for converting the detected analog measured values into digital measured values, a processing unit (15) and communication device (17) for processing and transmitting the digital measured values to the measuring and/or evaluating system or to the control system (19) according to a standard communication protocol of process technology.
US08766166B2
The present invention relates to a switch with multiple trigger function, which comprises: a touch switch having a button thereon; a first sensor having a sensing zone; and a microcontroller coupled to the touch switch and the first sensor; when the button is pressed by an object, the touch switch is conducted, and the microcontroller executes actions corresponding to the touch switch, thereby driving a controlled device; or when the object enters the sensing zone, the first sensor senses the signal change, and the microcontroller enables the touch switch to be conducted according to the signal change, or generates a signal the same as the signal for conducting the touch switch for executing corresponding actions, thereby driving a controlled device.
US08766164B2
An embodiment of a Geiger-mode avalanche photodiode includes a body of semiconductor material having a first conductivity type, a first surface and a second surface; a trench extending through the body from the first surface and surrounding an active region; a lateral-isolation region within the trench, formed by a conductive region and an insulating region of dielectric material, the insulating region surrounding the conductive region; an anode region having a second conductivity type, extending within the active region and facing the first surface. The active region forms a cathode region extending between the anode region and the second surface, and defines a quenching resistor. The photodiode has a contact region of conductive material, overlying the first surface and in contact with the conductive region for connection thereof to a circuit biasing the conductive region, thereby a depletion region is formed in the active region around the insulating region.
US08766158B2
A production method of a solid-state imaging device in which microlenses are arranged adjacent to each other on a substrate, includes: a first process of forming first microlenses on a surface of the substrate leaving space therebetween for providing second microlenses; and a second process of applying an overcoating material onto the surface of the substrate on which the first microlenses are formed, drying the overcoating material, exposing the overcoating material to light using a gray scale mask, and developing the exposed overcoating material, so as to form second microlenses in the space between the first microlenses adjacent to each other.
US08766156B2
A solid-state imaging device includes: a semiconductor substrate provided with an effective pixel region including a light receiving section that photoelectrically converts incident light; an interconnection layer that is provided at a plane side opposite to the light receiving plane of the semiconductor substrate; a first groove portion that is provided between adjacent light receiving sections and is formed at a predetermined depth from the light receiving plane side of the semiconductor substrate; and an insulating material that is embedded in at least a part of the first groove portion.
US08766144B2
According to another aspect, the subject application involves an oven and a method of controlling an oven for cooking a food item. The oven includes a cooking cavity, a user interface comprising an input device to be actuated with a single actuation event by a cook to select a predetermined cooking mode for cooking the food item, a heating element operable to produce heat required to cook the food item within the cooking cavity, and a control unit. The method includes receiving a cooking signal in response to actuation of the input device with the single actuation event by the cook, and establishing a cooking parameter for the predetermined cooking mode based on the cooking signal. The cooking parameter can be specific to the food item to be cooked according to the predetermined cooking mode of the oven. The method also includes initiating the predetermined cooking mode associated with the input device, and detecting that cooking of the food item according to the predetermined cooking mode is complete.
US08766135B2
A glass substrate laser cutting device according to the invention includes: a working table that has a plurality of vacuum absorbing grooves; a laser cutter; a pressure sensor that measures a pressure sensor when suctioning the glass substrate in a vacuum state; a calculation processing unit that compares the vacuum pressure measured by the pressure sensor with a predetermined threshold pressure and determines whether the glass substrate is broken; a laser cutter that includes a leaser head moving along the cutting direction of the glass substrate and emitting a laser beam; and an optical sensor that is attached to the laser head so as to move together and is disposed at a point in front of the laser beam emitted to the outside so as to detect the breakage of the glass substrate.
US08766131B2
A high-voltage switch includes a contact arrangement having two arcing contacts, one of which is supported displaceably against the action of a pretensioned spring. When the contact arrangement is closed, the free ends of the two arcing contacts are supported on one another. When the contact arrangement is opened, the two arcing contacts separate and during this process an arcing zone, accommodating compressed arc gas, is produced which is limited axially by free ends of the two arcing contacts and radially by an insulating nozzle toward the outside. To prevent the displaceably supported arcing contact from returning against the action of the pretensioned spring when a large short-circuit current is interrupted, the switch includes a piston/cylinder system functioning as a restoring device, which communicates with the arcing zone and which, with increasing pressure of the compressed arc gas produced in the arcing zone, generates a restoring force supporting the repelling force of the pretensioned spring.
US08766125B2
A D/A integrated pressure key for a keyboard is shown. A digital signal output first when a pressure is applied on the single key, and then an analog signal output while applying a bigger pressure over the same key. The magnitude of the analog signal output is positively related to the magnitude of the pressure applied on the integrated pressure key.
US08766121B2
A rotary on/off control switch (100, 700, 900) provides improved torque with single click operation. Rotary on/off control switch (100) is formed of a casing (106), a drive member (108), and a carrier member (110) having frictional elements (112) coupled thereto. A lever (116) and drive member (108) provide rotation of the carrier within the casing. In response to rotation of the drive member (108), carrier member (110) and lever (116), each frictional element (112) travels against the casing generating torque for single click ON operation. Rotation past a predetermined angle causes the carrier member (110) to remain stationary for variable function control of the rotary on/off control switch (100). Reverse rotation of the drive member (108), carrier member (110) and lever (116), generates torque for single click OFF operation.
US08766118B2
An actuator that includes a shelf having a pivot cone, a first member, a second member, a trigger pin and a trigger lever latch. The first member includes a weight, a first shaft extending upwardly from the weight and through an opening in the pivot cone, and a first plate affixed to the first shaft. The first plate is supported by the pivot cone. The second member includes a second plate resting on the first plate and a second shaft extending upwardly from the second plate. The trigger lever latch includes a first portion connected to the second shaft and a second portion extending upwardly at an angle away from the first portion. The trigger pin has an engagement surface. The trigger pin is movable between an operational state and a tripped state. The second end of the trigger lever latch is engaged with the engagement surface.
US08766092B2
An energy collection system is provided. The system can include an energy collection device and an energy concentration device disposed proximate at least a portion of the energy collection device. The energy concentration device includes a non-periodic, sub-wavelength, dielectric grating.
US08766088B2
A photovoltaic device can include a doped contact layer adjacent to a semiconductor absorber layer, where the doped contact layer includes a metal base material and a dopant.
US08766085B2
A photoelectric conversion device is provided in which a first photoelectric conversion module having a plurality of first photoelectric conversion elements formed on one surface of a first translucent insulated substrate and a second photoelectric conversion module having a plurality of photoelectric conversion elements formed on one surface of a second translucent insulated substrate are bonded together with the first photoelectric conversion elements and the second photoelectric conversion elements placed on an inner side. The photoelectric conversion device includes a plurality of photoelectric conversion element pairs formed by electrically connecting, in series, the first photoelectric conversion elements and the second photoelectric conversion elements arranged in positions opposed to each other. All the photoelectric conversion element pairs are electrically connected in series.
US08766084B2
A thermoelectric generation apparatus 1 including a high-temperature pipe 10through which a high-temperature fluid passes; a low-temperature pipe 20 disposed horizontally adjacent to the high-temperature pipe 10 and through which a low-temperature fluid having a temperature lower than that of the high-temperature fluid passes; a thermoelectric module 32 interposed between the high-temperature pipe 10 and the low-temperature pipe 20 and generating power using a temperature difference between the high-temperature pipe 10 and the low-temperature pipe 20; a fluid chamber 28 connected to an upper portion and a lower portion of the low-temperature pipe 20, parallel to the low-temperature pipe 20; and a fluid replenisher 110 capable of replenishing the fluid chamber 28 with the low-temperature fluid in a liquid state.
US08766083B2
A thermoelectric element includes at least one thermopair and a pn-junction. The thermopair has a first material with a positive Seebeck coefficient and a second material with a negative Seebeck coefficient. The first material is selectively contacted by way of a conductor with the p-side of the pn-junction, and the second material is selectively contacted by way of a conductor with the n-side of the pn-junction.
US08766080B2
Methods, systems, and media for performing visualized quantitative vibrato analysis are provided. In some embodiments, a method for analyzing musical vibrato in an audio file is provided, the method comprising: receiving, using a hardware processor, a target note from a user; receiving, using the hardware processor, a time-domain signal representing a piece of music comprising a plurality of notes, wherein the plurality of notes include the target note and the target note is played with a vibrato effect; converting, using the hardware processor, the time-domain signal to a frequency-domain signal; determining, using the hardware processor, a plurality of changes in frequency and intensity of the vibrato effect over time based on the frequency-domain signal; determining, using the hardware processor, a target frequency corresponding to the target note; and displaying, on a display, data about the changes in frequency and intensity of the vibrato effect over time and data about the target frequency.
US08766072B2
The reed for a saxophone according to an embodiment of the present invention is characterized in that one to six concave grooves are formed from a file mark 150 to a heel portion 120 in a longitudinal direction of the reed body 101 in a straight line, thus generating various tones with the aid of one to six concave grooves. In addition, an embodiment of the present invention makes it possible to generate deep and abundant tones with the aid of the increased vibrations of the reed, so the tones of a tenor saxophone can be expressed with an alto saxophone, which leads to a wide range of saxophone reed applications.
US08766069B2
A device for facilitating the stringing of a guitar is provided. More specifically, a device is provided that includes a head portion with at least one member for contacting and maintaining a first end of a guitar string around a cylindrical axle of a guitar bridge while the other end of the string is being interconnected to the tuning pegs of the instrument. Thus, the tool facilitates the stringing of a guitar by, for example, allowing the use of both hands to interconnect a second end of the guitar string to the tuning peg.
US08766060B1
A novel maize variety designated X08C963 and seed, plants and plant parts thereof, produced by crossing Pioneer Hi-Bred International, Inc. proprietary inbred maize varieties. Methods for producing a maize plant that comprises crossing hybrid maize variety X08C963 with another maize plant. Methods for producing a maize plant containing in its genetic material one or more traits introgressed into X08C963 through backcross conversion and/or transformation, and to the maize seed, plant and plant part produced thereby. This invention relates to the maize variety X08C963, the seed, the plant produced from the seed, and variants, mutants, and minor modifications of maize variety X08C963. This invention further relates to methods for producing maize varieties derived from maize variety X08C963.
US08766059B1
A novel maize variety designated PH18F6 and seed, plants and plant parts thereof. Methods for producing a maize plant that comprise crossing maize variety PH18F6 with another maize plant. Methods for producing a maize plant containing in its genetic material one or more traits introgressed into PH18F6 through backcross conversion and/or transformation, and to the maize seed, plant and plant part produced thereby. Hybrid maize seed, plant or plant part produced by crossing the variety PH18F6 or a locus conversion of PH18F6 with another maize variety.
US08766054B2
The present invention provides sweet bell pepper (Capsicum annuum) plants with high levels of resistance to Phytophthora combined with desirable agronomic traits. The present invention also provides methods of making such plants and methods of using such plants to produce additional Phytophthora-resistant sweet bell pepper plants.
US08766052B1
A soybean cultivar designated S120112 is disclosed. The invention relates to the seeds of soybean cultivar S120112, to the plants of soybean cultivar S120112, to the plant parts of soybean cultivar S120112, and to methods for producing progeny of soybean cultivar S120112. The invention also relates to methods for producing a soybean plant containing in its genetic material one or more transgenes and to the transgenic soybean plants and plant parts produced by those methods. The invention also relates to soybean cultivars or breeding cultivars, and plant parts derived from soybean cultivar S120112. The invention also relates to methods for producing other soybean cultivars, lines, or plant parts derived from soybean cultivar S120112, and to the soybean plants, varieties, and their parts derived from use of those methods. The invention further relates to hybrid soybean seeds, plants, and plant parts produced by crossing cultivar S120112 with another soybean cultivar.
US08766051B2
A soybean cultivar designated UA Kirksey is disclosed. The invention relates to the seeds of soybean cultivar UA Kirksey, to the plants of soybean cultivar UA Kirksey, to the plant parts of soybean cultivar UA Kirksey, and to methods for producing progeny of soybean cultivar UA Kirksey. The invention also relates to methods for producing a soybean plant containing in its genetic material one or more transgenes and to the transgenic soybean plants and plant parts produced by those methods. The invention also relates to soybean cultivars or breeding cultivars, and plant parts derived from soybean cultivar UA Kirksey. The invention also relates to methods for producing other soybean cultivars, lines, or plant parts derived from soybean cultivar UA Kirksey, and to the soybean plants, varieties, and their parts derived from use of those methods. The invention further relates to hybrid soybean seeds, plants, and plant parts produced by crossing cultivar UA Kirksey with another soybean cultivar.
US08766044B2
A novel soybean variety, designated XB25F12 is provided. Also provided are the seeds of soybean variety XB25F12, cells from soybean variety XB25F12, plants of soybean XB25F12, and plant parts of soybean variety XB25F12. Methods provided include producing a soybean plant by crossing soybean variety XB25F12 with another soybean plant, methods for introgressing a transgenic trait, a mutant trait, and/or a native trait into soybean variety XB25F12, methods for producing other soybean varieties or plant parts derived from soybean variety XB25F12, and methods of characterizing soybean variety XB25F12. Soybean seed, cells, plants, germplasm, breeding lines, varieties, and plant parts produced by these methods and/or derived from soybean variety XB25F12 are further provided.
US08766040B2
New Brassica Ogura fertility restorer lines with a shortened Raphanus fragment are provided. The new lines lack the OPC2 marker and are capable of fully restoring fertility in Ogura cytoplasmic male sterile (cms) plants. The improved lines were developed using a new breeding method. The new breeding method can be used to shorten an exotic insertion comprising a gene of interest in any plant.
US08766038B2
The present invention relates to methods for stimulating root growth and/or enhancing the formation of lateral or adventitious roots and/or altering root geotropism comprising expression of a plant cytokinin oxidase or comprising expression of another protein that reduces the level of active cytokinins in plants or plant parts. The invention also relates to novel plant cytokinin oxidase proteins, nucleic acid sequences encoding cytokinin oxidase proteins as well as to vectors, host cells, transgenic cells and plants comprising said sequences. The invention also relates to the use of said sequences for improving root-related characteristics including increasing yield and/or enhancing early vigor and/or modifying root/shoot ratio and/or improving resistance to lodging and/or increasing drought tolerance and/or promoting in vitro propagation of explants and/or modifying cell fate and/or plant development and/or plant morphology and/or plant biochemistry and/or plant physiology. The invention also relates to the use of said sequences in the above-mentioned methods. The invention also relates to methods for identifying and obtaining proteins and compounds interacting with cytokinin oxidase proteins. The invention also relates to the use of said compounds as a plant growth regulator or herbicide.
US08766036B1
The invention provides seed and plants of the hybrid corn variety designated 1669417. The invention thus relates to the plants, seeds and tissue cultures of the variety 1669417, and to methods for producing a corn plant produced by crossing a corn plant of variety 1669417 with itself or with another corn plant, such as a plant of another variety. The invention further relates to genetic complements of plants of variety 1669417.
US08766031B2
An absorbent article, preferably a disposable absorbent article such as a diaper, is disclosed that provides an improved immobilization of absorbent polymer material when the article is fully or partially urine loaded. This absorbent core is useful for providing an absorbent article of increased wearing comfort. Specifically disclosed is an absorbent core useful for an absorbent article comprising a substrate layer and absorbent material, the absorbent material comprising an absorbent polymer material, the absorbent material optionally comprising absorbent fibrous material, the absorbent fibrous material not representing more than 20% of the weight of absorbent polymer material, wherein the absorbent material is immobilized when wet such that the absorbent core achieves a wet immobilization of more than 50%, preferably of more than 60%, 70%, 80% or 90% according to the Wet Immobilization Test described herein.
US08766024B2
It has been discovered that the residence time of oils/fats in metal apparatus, particularly in the upstream of a hydrotreating unit, for example, a heat exchanger and/or a storage/feed tank, can impact significantly on corrosiveness of oils/fats in combination with and without conventional hydrocarbons. In addition, it is also found that the presence of hydrogen in the metal apparatus can also inhibit the corrosion rate of oils/fats.
US08766006B2
The present invention relates to the use of a nitroaniline derivative of Formula I for the production of nitric oxide and for the preparation of a medicament for the treatment of a disease wherein the administration of nitric oxide is beneficial. The present invention furthermore relates to a method for the production of NO irradiating a nitroaniline derivative of Formula I, a kit comprising a nitroaniline derivative of Formula I and a carrier and to a system comprising a source of radiations and a container associated to a nitroaniline derivative of Formula I. In Formula I, R and RI are each independently hydrogen or a C1-C3 alkyl group; RII is hydrogen or an alkyl group.
US08766005B2
The invention relates to a process for producing pharmaceutically acceptable salts of fingolimod (I), comprising the step of reacting N-[1,1-bis hydroxymethyl-3-(4-octyl phenyl)-propyl]-acylamide (II) with an acidic compound. Furthermore, the invention provides different pharmaceutically acceptable salts of fingolimod and a polymorphic form of fingolimod hydrochloride.
US08766004B2
The present invention relates to a method for preparing aryl aldimines. In particular, the present invention relates to methods of preparing aryl aldimines that uses environmentally friendly solvent systems.
US08766000B2
The present invention relates to a method for continuously preparing a betaine aqueous solution, including the reaction of an amine with an ω-halocarboxylic acid, in the presence of water and a base. Said method is characterized in that it is carried out in a device consisting of at least two consecutive reactors (R1) and (R2), the reactor (R2) being a tubular reactor.
US08765999B2
Disclosed is a process for the production and purification of glycolic acid or glycolic acid derivatives by the carbonylation of formaldehyde in the presence of a homogeneous acid catalyst and a carboxylic acid. This invention discloses hydrocarboxylations and corresponding homogeneous acid catalyst and glycolic acid separations. The homogeneous acid catalyst is readily separated from the hydrocarboxylation reaction effluent and recycled and the carboxylic acid is readily removed from the glycolic acid and the carboxylic acid is recycled.
US08765992B2
The invention relates to methods for producing chalcone (1,3-diphenylprop-2-en-1-one) derivatives that have multiple substitutions on a phenyl ring. Intermediate chalcone derivatives are modified by Phase Transfer Catalysis (PTC) for introducing a substituted alkyl group that is provided by a sulfonic acid derivative on a phenyl ring already containing substituent groups on one or two carbon atoms adjacent to the carbon atom where a substituent group is being introduced. The methods of the invention allow producing efficiently, by either S-alkylation or O-alkylation, chalcones derivatives that are characterized for their biological activities that are intermediate compounds for producing molecules having such activities, or that can be used for generating libraries of compounds to be screened by means of in vitro and/or in vivo assays and establishing structure-activity relationships.
US08765981B2
A process for producing an olefin oxide which comprises reacting an olefin with oxygen in the presence of a catalyst comprising a copper oxide and a tellurium oxide.
US08765974B2
Disclosed is a method for producing a tetrahydropyran compound represented by general formula (5) shown in the scheme. Accordingly, a tetrahydropyran derivative is obtained in high yield and with high selectivity without using a highly toxic reagent, and an industrially useful method for producing a tetrahydropyran derivative and an intermediate thereof can be provided. In formulae (1) to (5), R1 and R2 each independently represent a hydrogen atom, a linear, branched, or cyclic alkyl group, or an aromatic group which may have a substituent, and R1 and R2may be combined to form an alkylene group, thereby forming a ring; and R3 and R4 each independently represent a hydrogen atom or a linear, branched, or cyclic alkyl group, and R3 and R4 may be combined to form an alkylene group, thereby forming a ring.
US08765973B2
The invention is directed to compounds according to formula (I): where R1 is L1C(O)OT or L1C(O)OL2C(O)OT; R2 is a substituted or unsubstituted C1-C10 alkyl, C2-C10 alkenyl, or C2-C10 alkynyl, or R1; n is an integer from 0 to 5; each R3 is independently halogen or R2; R4 and R5 are independently H, halogen, CN or CF3; L1 and L2 are each independently a bond, a substituted or unsubstituted C1-C10 alkylene, C2-C10 alkenylene, or C2-C10 alkynylene; and T is H, a substituted or unsubstituted C1-C10 alkyl, C2-C10 alkenyl, or C2-C10 alkynyl, nitrophenol, or cyclopropyl. The invention is also directed to a pharmaceutical composition comprising a compound according to formula (I) and a pharmaceutically acceptable carrier, and to methods for providing anesthesia in mammals by administering such a pharmaceutical composition.
US08765963B2
The invention relates to fatty acid niacin conjugates; compositions comprising an effective amount of a fatty acid niacin conjugate; and methods for treating or preventing an metabolic disease comprising the administration of an effective amount of a fatty acid niacin conjugate.
US08765957B2
The invention provides a process for the preparation of a compound of Formula 1, comprising coupling a carboxylic acid of Formula 2 with an aniline of Formula 3 in the presence of a coupling agent.
US08765953B2
The present invention relates generally to alkyne containing pharmaceutical agents, and in particular, to phenylethynyl-thiophene based metalloprotease inhibitor compounds. More particularly, the present invention provides a new class of MMP inhibiting compounds that exhibit increased potency, metabolic stability and/or reduced toxicity in relation to currently known MMP inhibitors for the treatment of pain and other diseases such as cancer. Additionally, the present invention relates to methods for treating pain in a patient comprising administering to the patient a pain-reducing effective amount of a present compound.
US08765947B2
A preparation method of rosuvastatin calcium (Formula 1), which can be used for the production of medicament lowering the levels of LDL-cholesterol and triglycerides in vivo, is provided. Such preparation method is suitable for industrial production. Furthermore, the intermediate crystallines used in the preparation method are provided.
US08765946B2
A method of preparing a compound of formula (I), A method for treating cancer or inhibiting growth of cancer cells including administering to a patient mammal in need thereof a pharmaceutical preparation including the compound. A method of treating or preventing a physiological disorder caused by abnormal protein tyrosine kinase activity in a mammal including administering to a mammal a pharmaceutical preparation including the compound.
US08765944B2
The disclosure provides compounds of formula I, including pharmaceutically acceptable salts, as well as compositions and methods of using the compounds. The compounds have activity against hepatitis C virus (HCV) and may be useful in treating those infected with HCV.
US08765940B2
Substituted bicyclic heteroaryls and compositions containing them, for the treatment of general inflammation, arthritis, rheumatic diseases, osteoarthritis, inflammatory bowel disorders, inflammatory eye disorders, inflammatory or unstable bladder disorders, psoriasis, skin complaints with inflammatory components, chronic inflammatory conditions, including but not restricted to autoimmune diseases such as systemic lupus erythematosis (SLE), myestenia gravis, rheumatoid arthritis, acute disseminated encephalomyelitis, idiopathic thrombocytopenic purpura, multiples sclerosis, Sjoegren's syndrome and autoimmune hemolytic anemia, allergic conditions including all forms of hypersensitivity, The present invention also enables methods for treating cancers that are mediated, dependent on or associated with p110 activity, including but not restricted to leukemias, such as Acute Myeloid leukaemia (AML) Myelo-dysplastic syndrome (MDS) myelo-proliferative diseases (MPD) Chronic Myeloid Leukemia (CML) T-cell Acute Lymphoblastic leukaemia (T-ALL) B-cell Acute Lymphoblastic leukaemia (B-ALL) Non Hodgkins Lymphoma (NHL) B-cell lymphoma and solid tumors, such as breast cancer.
US08765938B2
The object is to produce a polysaccharide and/or a monosaccharide efficiently by hydrolyzing a different polysaccharide efficiently. The hydrolysis of a polysaccharide is an important means for producing a monosaccharide that can be used as a starting material for the production of ethanol, the solubilization of a water-insoluble polysaccharide, and the production of a useful water-soluble low-polymeric saccharide or the like. For achieving the object, a polysaccharide to be hydrolyzed is reacted with water in the presence of a carbonaceous material having sulfonic acid group therein to cause the hydrolysis of the polysaccharide to be hydrolyzed, thereby producing a other polysaccharide and/or a monosaccharide.
US08765926B2
The present invention pertains to a supramolecular structure based on i-motif tetramers of Cm—X—Cn oligonucleotides, wherein m and n are integers comprised between 2 and 9, and X is a linker such as A, T, G, a modified deoxynucleotide or a diol spacer. These supramolecular structures can be dissociated, when necessary, by a mere pH change. The present invention also relates to methods for obtaining such a supramolecular structure.
US08765925B2
A method for preparation of Timosaponin BII, which uses Chinese traditional medicine Rhizoma Anemarrhenae or fresh rhizoma or fibrous root of Anemarrhena asphodeloides Bge. as raw material, and comprises isolation of Timosaponin BII by one or more processes selected from solvent extraction, resin adsorption, polyamide chromatography, reversed phase column chromatography, Sephadex LH-20 column chromatography, etc, combining with conventional drying method such as reduced pressure drying, freeze drying, spray drying, and so on. Timosaponin BII obtained by the present method is of over 90% purity, and the method is simple, practicable and suitable for industrial production.
US08765923B2
Methods for selective extraction and fractionation of algal proteins from an algal biomass or algal culture are disclosed. A method of selective removal of products from an algal biomass provides for single and multistep extraction processes which allow for efficient separation of algal proteins. These proteins can be used as renewable sources of proteins for animal feedstocks and human food. Further, lipids remaining in the algal biomass after extraction of proteins can be used to generate renewable fuels.
US08765922B2
A method and associated device for enrichment of Neél-magnetic particles from a dispersion of Brown-magnetic particles and Neél-magnetic particles. The device and method use ferromagnetic separation particles having a mean diameter of 100 to 250 μm located in a alternating magnetic field. The ferromagnetic separation particles have a magnetically and chemically inert coating.
US08765920B2
A new and versatile class of cyclic diazodicarboxamides that reacts efficiently and selectively with phenols and the phenolic side chain of tyrosine through an Ene-like reaction is reported. This mild aqueous tyrosine ligation reaction works over a broad pH range and expands the repertoire of aqueous chemistries available for small molecule, peptide, and protein modification. The tyrosine ligation reactions are shown to be compatible with the labeling of native enzymes and antibodies in buffered aqueous solution. This reaction provides a novel synthetic approach to bispecific antibodies. This reaction will find broad utility in peptide and protein chemistry and in the chemistry of phenol-containing compounds.
US08765917B2
Novel anti-cancer agents, including, but not limited to, antibodies and immunoconjugates, that bind to CD37 are provided. Methods of using the agents, antibodies, or immunoconjugates, such as methods of inhibiting tumor growth are further provided.
US08765915B2
The present invention relates to the fields of Factor VII (FVII) and Factor VIIa (FVIIa) albumin linked polypeptides. More specifically, the invention relates to cDNA sequences coding for human Factor VII and Factor VIIa and derivatives genetically fused to a cDNA coding for human serum albumin which may be linked by oligonucleotides which code for intervening peptidic linkers such encoded derivatives exhibiting improved stability and extended functional plasma half-life, recombinant expression vectors containing such cDNA sequences, host cells transformed with such recombinant expression vectors, recombinant polypeptides and derivatives which do have biological activities of the unmodified wild type protein but having improved stability and prolonged shelf-life and processes for the manufacture of such recombinant proteins and their derivatives. The invention also covers a transfer vector for use in human gene therapy, which comprises such modified DNA sequences.
US08765914B2
Purified genes encoding a cytokine referred to as interleukin-B30 (IL-B30) from a mammal, and reagents related thereto including purified proteins, specific antibodies, and nucleic acids encoding this molecule are provided. Methods of using the reagents and diagnostic kits are also provided.
US08765913B2
The present invention relates to compositions and methods for characterizing, diagnosing, and treating cancer. In particular the invention provides the means and methods for the diagnosis, characterization, prognosis and treatment of cancer and specifically targeting cancer stem cells. The present invention provides a soluble FZD receptor comprising an extracellular domain of a human FZD receptor that inhibits growth of tumor cells. The present invention still further provides a soluble receptor comprising a Fri domain of a human FZD receptor that binds a ligand of a human FZD receptor and said soluble receptor is capable of inhibiting tumor growth. The present invention still further provides a method of treating cancer comprising administering a soluble FZD receptor comprising for example, either an extracellular domain of a human FZD receptor or a Fri domain of a human FZD receptor, in an amount effective to inhibit tumor growth.
US08765900B2
The present disclosure is directed to an aliphatic isocyanate-based moisture-curable resin. The disclosed resin may include an aliphatic isocyanate functional material and an cycloaliphatic isocyanate functional material. The resin may be used to formulate a coating composition that may exhibit no substantial sag when applied at a wet film thickness of at least 6 mils, and no substantial blistering when cured to a dry film thickness of at least 6 mils.
US08765897B2
The present invention relates to a hydrophilic crosslinked polymer, preferably in the form of porous particles, and to the preparation and use thereof. The polymer according to the invention is produced by polymerization from chain-forming hydrophilic vinyl ethers and crosslinking, preferably heterocyclic divinyl ethers.
US08765889B2
The invention relates to a method for producing hybrid-particles containing polymer and SiO2-particles, wherein a) in a first polymerization step in aqueous medium a water-insoluble phase containing one or more monomeric and colloidal SiO2-particles having an average particle diameter of 1 to 150 nm are polymerized, and b) in a second polymerization step in aqueous medium one or more monomers are polymerized in the presence of the polymer obtained in the first polymerization step.
US08765878B2
Provided is a resin composition including a compound in which a vinyl group in a side chain of a phosphazene compound is bonded to an α carbon in an aliphatic polyester resin.
US08765876B2
Fluoroelastomer compositions comprising fluoroelastomers having copolymerized units of a nitrile-containing cure site monomer are cured with certain hydrazide curatives. The hydrazide is of the general formula R1(C(O))nNHNHR2, wherein n is 1 or 2; R1 is NH2, NHNH2, NHR3, NR32, NHNHC(O)NH2, NHNHC(O)NHNH2, NHNHR2, or NHC(O)NHNH2; R2 is H, alkyl, aryl, heterocycle, CO2R3, C(O)R3, CH2R4, or C(O)R4; R3 is alkyl, aryl, heterocycle, or CH2R4; and R4 is a fluoroalkyl group.
US08765875B2
Fluoroelastomer compositions comprising fluoroelastomers having copolymerized units of a nitrile-containing cure site monomer are cured with certain hydrazide curatives. The hydrazide is of the general formula R1C(O)NHNHR2, wherein R1 is alkyl, aryl, benzyl, heterocycle, fluoroalkyl, or H; R2 is H, alkyl, aryl, heterocycle, CO2R3, C(O)H, or CH2R4; R3 is alkyl, CH2R4, aryl, benzyl, or heterocycle; and R4 is a fluoroalkyl group.
US08765868B2
A resin composition includes: (A) a polymer having a structural unit shown by the formula (I), and an acidic functional group or a group derived therefrom at both of the terminals; wherein X1 is a di- to octa-valent organic group, Y1 is a di- to octa-valent organic group, R1 is a hydrogen atom or an organic group having 1 to 20 carbon atoms, R2 is a hydrogen atom or a monovalent organic group, when plural R1s or R2s exist, the plural R1s or R2s may be the same or different, p and q are independently an integer of 0 to 4, l and m are independently an integer of 0 to 2, and n is an integer of 2 or more indicating the number of structural units; (B) a solvent; and (C) a compound shown by formula (II) wherein R3 is a monovalent organic group.
US08765861B2
A masterbatch pellet is provided for obtaining a polyamide resin composition excellent in mechanical strength and heat aging resistance. The masterbatch pellet is obtained by melt-kneading a raw material component containing a thermoplastic resin (A) and a metal oxide (B), wherein a content of the metal oxide (B) is 0.5% by mass or more and a fraction of the metal oxide (B) after the melt kneading is present as an aggregated particle of 5 μm or more in a major axis length. A proportion of the aggregated particle of 5 μm or more in a major axis length in a whole metal oxide after the melt kneading is preferably 30% by mass or less.
US08765856B2
A lead-free, non-toxic composite material including a thermosetting polymer and at least one of a heavy particulate filler, a light particulate filler or a combination thereof. The composite material may be utilized in manufacturing articles used in radiation shielding applications.
US08765851B2
A hot melt adhesive composition that includes a first copolymer that includes the reaction product of a functionalized polyethylene, a propylene-alpha-olefin polymer that includes at least 50 mole % propylene and has a viscosity of no greater than 10,000 centipoise at 190° C., a ratio of z average molecular weight (Mz) to number average molecular weight (Mn) (Mz/Mn) of greater than 20, and a ratio of Mz to weight average molecular weight (Mw) (Mz/Mw) of greater than 3.0, and a free radical initiator.
US08765847B2
Methods are provided for upgrading the quality of an asphalt. The methods include mixing an asphalt feed with a cracking resistance additive that improves the low temperature properties of the asphalt while leaving the high temperature properties unchanged or minimally changed. The cracking resistance additive corresponds to a compound that is a liquid at both the low temperature performance grade for the asphalt and at mixing and/or storage temperature for the asphalt. Examples of compounds that, in an appropriate molecular weight range, are liquids across this broad temperature range include polyalphaolefins, alkylated naphthalenes, and organic esters.
US08765845B2
Compositions comprising a hydraulic binder such as cement or gypsum and a hydroxypropyl guar derivative that comprises unsubstituted linear or branched C6-C8 alkyl chains possess excellent water retention characteristics.
US08765844B2
A manufacturing method of rubber composition for tire tread or the other, which is comprised of adding 30-110 mass parts of silica powders to 100 mass parts of diene rubber component and adding silane coupling agent by 3-15 mass % of the silica powders, comprising: preparing hetero-modified SBR having hetero atom functional group; a first kneader-mixing step, in which 60-85 mass parts of the diene rubber component including no less than 20 mass % of the hetero-modified SBR is mixed in a kneader device with substantially all of the reinforcing fillers; taking out of obtained mixture to give a master batch; and second kneader-mixing step, in which the master batch is mixed substantially solely with remaining mass parts of the diene component.
US08765841B2
Disclosed is a composition, useful for a coating material, comprising coal ash and latex polymer and optionally a hydraulic binder, a superplasticizer, a rheology modifier, a filler, an aggregate, a foaming agent, a de-foaming agent, an accelerant and/or a retardant. The composition possesses favorable physicochemical properties and a low carbon footprint.
US08765836B2
A dental appliance comprising a hard, shaped body having at least one portion comprising a polymerized blend of: From 0% to about 50% of an uncrosslinked polymer capable of dissolving in component; From about 0% to 50% of a monofunctional polymerizable monomer; From about 0% to 40% of a highly crosslinked polymer in the form of ground particles having average diameters up to about 500 microns; From about 0% to 50% of a crosslinked polymer in the form of discrete particles having average diameters up to about 500 microns and being easily swellable by said monomer; and From about 5% to about 35% of a di- or polyfunctional crosslinking agent.
US08765832B2
Provided is a method for providing a composition comprising at least one propylene-based polymer; at least one of multifunctional acrylates, multifunctional methacrylates, functionalized polybutadiene resins, functionalized cyanurate, and allyl isocyanurate; at least one of hindered phenols, phosphites, and hindered amines; and at least one photoinitiator for UV curing. The propylene-based polymer can include propylene derived units and one or more dienes, and have a triad tacticity of from 50% to 99% and a heat of fusion of less than 80 J/g. The composition can be extruded and crosslinked. The crosslinked composition is particularly useful for making films and fibers.
US08765820B2
Tranylcypromine derivatives useful as therapeutic agents, particularly for the prevention and/or treatment of diseases and conditions associated with the activity of histone demethylases LSD1 and LSD2, such as the diseases characterized by deregulation of gene transcription, cell differentiation and proliferation, e.g. tumors, viral infections, are herein described. These compounds belong to the structural formula (I) wherein A and R3 are as defined in the specification. The invention also relates to the preparation of these compounds, as well as to compositions containing them and to therapeutic use thereof.
US08765816B2
Compounds that are central nervous system drug candidates for the treatment of cognitive decline and, more particularly, Alzheimer's disease are provided. Methods of treating, inhibiting, and/or abatement of cognitive decline and/or Alzheimer's disease with a compound or pharmaceutically acceptable salt of the invention are also provided. Also provided are methods of preparing the compounds/compositions of the invention.
US08765813B2
The present disclosure relates to novel methods for using treprostinil or its derivative, or a pharmaceutically acceptable salt thereof, for the treatment and/or prevention of ischemic lesions, such as digital ulcers, in subjects with scleroderma (including systemic sclerosis), Buerger's disease, Raynaud's disease, Raynaud's phenomenon and/or other conditions that cause such lesions. The disclosure also relates to kits for treatment and/or prevention of ischemic lesions, which include an effective amount of treprostinil or its derivative, or a pharmaceutically acceptable salt thereof.
US08765810B2
The present invention is directed to compounds that are allosteric inhibitors of tumor necrosis factor receptor I, compositions comprising such compounds, and methods of using such compounds and compositions thereof in the treatment of TNF-α mediated conditions.
US08765808B2
The NSAID, sulindac and/or its metabolites and derivatives, in combination with hydrogen peroxide or another oxidizing agent, such as arsenic trioxide that generates reactive oxygen species (ROS), significantly enhances the killing of cancer cells. This effect occurs at concentrations of each compound that individually have little or no activity directed against cancer cells. A skin cream has been developed and used to treat skin cancer and precancerous skin growths that effectively removes the lesions with no effect on surrounding normal skin.
US08765807B2
The present invention relates to the formulations of ester derivatives of capsaicin and ester derivatives of myristoleic acid. These derivatives are capable of reverting to the active parent compound following enzymatic or chemical hydrolysis. These derivatives have a higher lipophilicity, lipid solubility and less irritation to the skin than the parent compound, and hence are better able to be incorporated into certain pharmaceutical formulations, including cream and ointment pharmaceutical formulations. The pharmaceutical compositions are useful for pain management in mammals in vivo and have been contemplated to be used in the treatment of various pains in humans.
US08765805B2
Novel ligand compounds having the structural formula (I): in which: Ar is a radical selected from among the radicals of formulae (a)-(c) below: are formulated into pharmaceutical compositions suited for administration in human or veterinary medicine, or, alternatively into cosmetic compositions.
US08765795B2
A preservative which comprises a) one or more isothiazolones and b) one or more glycerol monoalkyl ethers, and the use of the preservative for microbicidal finishing of cosmetic and pharmaceutical products.
US08765779B2
This application relates to tricyclic compounds of Formula I: including all stereoisomers, mixtures of stereoisomers, and salts thereof. This application also relates to compositions comprising compounds of Formula I and uses therefore.
US08765774B2
The present invention relates to the 3-arylquinazolin-4-one compounds of the formula I and the salts thereof, wherein n is 0, 1 or 2; X is O, S or N—R4; Y1 is N or CH; Y2 is N or C—R5; R1 is C1-C10-alkyl, C1-C10-haloalkyl, C2-C10-alkenyl, C2-C10-haloalkenyl, C2-C10-alkynyl, C2-C10-haloalkynyl, C3-C12-cycloalkyl, C5-C12-cycloalkenyl, C3-C12-cycloalkyl-C1-C4-alkyl, C5-C12-cycloalkenyl-C1-C4-alkyl, where the cycloalkyl radical and the cycloalkenyl radical in the last four mentioned radicals are unsubstituted, partially or fully halogenated and/or carry 1, 2, 3, 4, or 5 C1-C4-alkyl radicals; R2 is hydrogen, halogen, CN, C(Z)NH2, C1-C4-alkyl or C1-C4-haloalkyl, wherein Z is O, S or NR6; and the variables k, R, R3, R4, R5 and R6 are as defined in the claims. The invention also relates to the use of novel compounds of formula I for combating invertebrate pests and to a method for controlling invertebrate pests. The invention also relates to a plant propagation material and to an agricultural composition comprising a 3-arylquinazolin-4-one compound of formula I.
US08765772B2
The present invention relates to compounds of formula (I): wherein R1 is C1-6alkylamino, C1-6alkoxy, or C3-7cycloalkyloxy; m is an integer having a value of 3 to 6; n is an integer having a value of 0 to 4; and salts thereof are inducers of human interferon. Compounds which induce human interferon may be useful in the treatment of various disorders, for example the treatment of allergic diseases and other inflammatory conditions for example allergic rhinitis and asthma, the treatment of infectious diseases and cancer, and may also be useful as vaccine adjuvants.
US08765765B2
The present invention relates to metabolites of(thio)-carbamoyl cyclohexane derivatives, particularly, metabolites of trans-4-{2-[4-(2,3-dichlorophenyl)-piperazin-1-yl]-ethyl}-N,N-dimethylcarbamoyl-cyclohexylamine and pharmaceutically acceptable salts thereof, to pharmaceutical compositions containing the same and to their use in the treatment and/or prevention of a conditions which requires modulation of dopamine receptors.
US08765757B2
The present invention relates to 3-Heterocyclic Substituted Indole Derivatives, compositions comprising at least one 3-Heterocyclic Substituted Indole Derivative, and methods of using the 3-Heterocyclic Substituted Indole Derivatives for treating or preventing a viral infection or a virus-related disorder in a patient.
US08765753B2
A process is described for the preparation of s-triazine derivatives of the formula in which R is a C1-C12-alkyl radical, by reacting a cyanuric acid halide with a p-aminobenzoic acid ester, which comprises a C6-C12-alkyl radical as radical of the ester alcohol, in a molar ratio of 1:3 to 1:5 in a xylene isomer mixture as solvent. 10 The process is characterized in that the solvent is used in amounts of from 0.6 to 2.1 mol/l.
US08765750B2
The present invention provides a piperazine compound represented by Formula (I) or a salt thereof, wherein X represents CH or an N atom; R1 represents C1-6 alkyl; R2 represents C1-6 alkyl that may have one or more substituents, C2-6 alkenyl that may have one or more substituents, —(C═O)—N(R3)(R4), or —(C═O)—OR5, R3 and R4 are the same or different, and each represents hydrogen or C1-6 alkyl that may have one or more substituents; or R3 and R4, taken together with a nitrogen atom to which R3 and R4 are attached, may form a saturated heterocyclic group; and R5 represents hydrogen or C1-6 alkyl that may have one or more substituents or aralkyl.
US08765747B2
The present application relates to therapeutic organic compounds of formula (I), wherein Q, R1, R2, R3, and R4 are defined herein. The invention also relates to pharmaceutical compositions comprising an effective amount of a therapeutic organic compound; and methods for treating and preventing disease such as cancer comprising administering and effective amount of a therapeutic organic compound to a subject in need thereof.
US08765737B1
Disclosed are methods and compositions for purifying the non-addictive alkaloid noribogaine.
US08765732B2
The present invention relates to aryl- or heteroaryl-substituted benzene compounds. The present invention also relates to pharmaceutical compositions containing these compounds and methods of treating cancer by administering these compounds and pharmaceutical compositions to subjects in need thereof. The present invention also relates to the use of such compounds for research or other non-therapeutic purposes.
US08765710B2
Embodiments of the invention are to compounds, methods, and compositions for use in the treatment of viral infections. More specifically embodiments of the invention are 2′,4′-substituted nucleoside compounds useful for the treatment of viral infections, such as HIV, HCV, and HBV infections.
US08765708B2
The present invention relates to novel compositions and therapeutic methods for the treatment of cancer, in particular malignant glioma. The compositions include antisense oligonucleotides or RNAs or vectors encoding them which reduce expression of downregulated in renal cell carcinoma (DRR) in tumor cells, and inhibit malignant glioma cell invasion.
US08765705B2
Oligonucleotides inhibiting cellular migration, and the use of at least one inhibitor of protein expression, which inhibits the expression of TSP1 protein, or a protein, which controls the expression of TSP1 or mediates the activity of TSP1, or one inhibitor of protein activity, this inhibitor inhibiting the activity of the TSP1 protein, in particular the activity responsible for the stimulation of cell migration, or one protein which controls the expression or mediates the activity of TSP1 for the manufacture of a drug for the prevention or the treatment of primary tumors or invasive or metastatic tumors.
US08765704B1
The present invention provides double-stranded RNA molecules that mediate RNA interference in target cells, preferably hepatic cells. The invention also provides double-stranded RNA (dsRNA) molecules that are modified to be resistant to nuclease degradation, which inactivates a virus, and more specifically, hepatitis C virus (HCV). The invention also provides a method of using these modified RNA molecules to inactivate virus in mammalian cells and a method of making modified small interfering RNAs (siRNAs) using human Dicer. The invention provides modified RNA molecules that are modified to include a dsRNA or siRNA wherein one or more of the pyrimidines in the RNA molecule are modified to include 2′-Fluorine. The invention also provides dsRNA or siRNA in which all pyrimidines are modified to include a 2′-Fluorine. The invention provides that the 2′-Fluorine dsRNA or siRNA molecule is further modified to include a two base deoxynucleotide “TT” sequence at the 3′ end of the molecule.
US08765699B2
The invention relates to a double-stranded compound, preferably an oligoribonucleotide, which down-regulates the expression of a human p53 gene. The invention also relates to a pharmaceutical composition comprising the compound, or a vector capable of expressing the oligoribonucleotide compound, and a pharmaceutically acceptable carrier. The present invention also contemplates a method of treating a patient suffering from alopecia or acute renal failure or other diseases comprising administering to the patient the pharmaceutical composition in a therapeutically effective dose so as to thereby treat the patient. The alopecia may be induced by chemotherapy or radiotherapy, and the patient may be suffering from cancer, in particular breast cancer.
US08765698B2
Products and methods are provided for the restoring the endogenous expression of theta-defensins, such as retrocyclin-1, in mamallian cells. The present invention also includes products and methods for inhibiting sexually transmitted virus entry, e.g., HIV-1 virus entry, into a mammalian cell via, for example, administering to a subject an amount of a read-through mediating agent sufficient to induce exogenous expression of an amount of retrocyclin nonapeptides in the mammalian cell.
US08765694B2
The present invention is directed to methods for treating obesity, reducing excessive body weight, treating an obesity-related condition, treating unwanted localized fat deposits, and treating areas of cellulite. The method comprises the steps of first identifying a subject in need thereof, and administering to the subject an effective amount of rhamnolipids. A pharmaceutical composition comprising rhamnolipids can be applied by any accepted mode of administration including oral, intranasal, subcutaneous, percutaneous, intravenous, or intracutaneous administration.
US08765692B2
Modified glycolipid compounds are provided. Also disclosed are methods for activating an NKT cell, methods of stimulating an immune response in a subject, and methods suitable for labeling NKT cells.
US08765690B2
The co-administration of glufosfamide and a glucose lowering drug other than insulin is efficacious in cancer treatment.
US08765676B2
Calcium-sensing receptor (CaSR) modulating substituted cyclopentylene compounds represented in formula I (wherein X is CH or N) and pharmaceutical compositions thereof are useful for treating diseases.
US08765675B2
The present invention relates to a novel use of calcitonin in osteoarthritis, and to methods of treating and/or preventing osteoarthritis in mammals, particularly humans.
US08765667B2
Novel compounds that are potent inhibitors of hepatitis C virus protease are provided. Pharmaceutical compositions containing one or more of these inhibitors, methods of preparing the inhibitors and methods of using the inhibitors to treat hepatitis C and related disorders also are provided.
US08765665B2
A Factor VIII composition formulated without albumin, comprising the following formulation excipients in addition to Factor VIII: 4% to 10% of a bulking agent selected from the group consisting of mannitol, glycine and alanine; 1% to 4% of a stabilizing agent selected from the group consisting of sucrose, trehalose, raffinose, and arginine; 1 mM to 5 mM calcium salt; 100 mM to 300 mM NaCl; and a buffering agent for maintaining a pH of approximately between 6 and 8. Alternatively, the formulation can comprise 2% to 6% hydroxyethyl starch; 1% to 4% of a stabilizing agent selected from the group consisting of sucrose, trehalose, raffinose, and arginine; 1 mM to 5 mM calcium salt; 100 mM to 300 mM NaCl; and a buffering agent for maintaining a pH of approximately between 6 and 8. In a further embodiment, the formulation can comprise: 300 mM to 500 mM NaCl; 1% to 4% of a stabilizing agent selected from the group consisting of sucrose, trehalose, raffinose, and arginine; 1 mM to 5 mM calcium salt; and a buffering agent.
US08765658B2
A method for preparing an emulsion cleaning composition that is resistant to separation upon exposure to depressed and elevated temperatures and which exhibits a persistent peroxide content comprises preparing an organic portion and an oxidant portion and then combining the organic portion and the oxidant portion under mixing to make the emulsion. The organic portion comprises an organic solvent, and emulsifier and a cleaner surfactant. The oxidant portion comprises an oxidizing compound activator and a peroxide generator. The emulsion cleaning composition is useful for removing petroleum distillate residue from metal surfaces such as refinery surfaces.
US08765652B2
The present invention relates to reagents for use in deactivating nucleic acids and methods of making and using the same.
US08765650B2
A composition of an oil-soluble ionic detergent that does not contribute metal ions to the composition, and which comprises a quaternary non-metallic pnictogen cation and an organic anion having at least one hydrocarbyl group of sufficient length to impart oil solubility to the detergent, the detergent having a total base number (TBN) to total acid number (TAN) ratio of at least 2:1 imparts ash-free basicity to a lubricant composition.
US08765641B2
An antibody microarray screen including a substrate, monoclonal and polyclonal antibodies that are purified immunoglobins, wherein the antibodies are spotted on predetermined positions on the substrate, and fluids unprocessed for immunoglobulin isolation (e.g., anti-sera, ascites fluids, or hybridoma culture media), wherein the unprocessed fluids are spotted on the predetermined positions on the substrate. Production of drug-metabolizing enzyme antibody microarrays containing closely related cytochromes P450 is disclosed. Methods of manufacturing an antibody microarray, an internal control molecule for use in an antibody microarray, a method of determining optimal spotting concentrations of IgG and a method to increase a detectable signal with microarray analysis are disclosed.
US08765636B2
The present invention relates to novel active compound combinations comprising a known carboxamide, a known azole and additionally a second known azole or alternatively a known strobilurin, which combinations are highly suitable for controlling unwanted phytopathogenic fungi.
US08765628B2
Exemplary embodiments of the present invention relate to the processing of hydrocarbon-containing feedstreams in the presence of an active catalyst component comprising a surface, and a metal oxide film coated on the surface of the active catalyst component. The catalysts and processes of the present invention can improve overall hydrogenation, product conversion, as well as improved resistance to catalytic deactivation due to sulfur and nitrogen compounds present in the hydrocarbon feedstreams.
US08765620B2
A fused and cast refractory product containing, in weight percentages on the basis of the oxides and for a total of 100%: ZrO2: remainder up to 100% Hf2O: <5% SiO2: 2% to 10% 0.9%
US08765618B2
A thermal processing apparatus and method in which a first laser source, for example, a CO2 emitting at 10.6 μm is focused onto a silicon wafer as a line beam and a second laser source, for example, a GaAs laser bar emitting at 808 nm is focused onto the wafer as a larger beam surrounding the line beam. The two beams are scanned in synchronism in the direction of the narrow dimension of the line beam to create a narrow heating pulse from the line beam when activated by the larger beam. The energy of GaAs radiation is greater than the silicon bandgap energy and creates free carriers. The energy of the CO2 radiation is less than the silicon bandgap energy so silicon is otherwise transparent to it, but the long wavelength radiation is absorbed by the free carriers.
US08765611B2
A process for etching semiconductors, such as II-VI or III-V semiconductors is provided. The method includes sputter etching the semiconductor through an etching mask using a nonreactive gas, removing the semiconductor and cleaning the chamber with a reactive gas. The etching mask includes a photoresist. Using this method, light-emitting diodes with light extracting elements or nano/micro-structures etched into the semiconductor material can be fabricated.
US08765610B2
According to one embodiment, a method for manufacturing a semiconductor device includes forming a plurality of second core films, the second core film having a first array portion, and a second array portion which is arranged so as to be spaced at a larger second space than the first space in the first direction from the first array portion, the second space being positioned above the loop portion. The method includes processing the second film to be processed below the first array portion into a second line and space pattern which includes a second line pattern extending in the second direction, and removing the second film to be processed below the second space and the loop portion of the first film to be processed, by an etching using the second spacer film as a mask.
US08765609B2
A process for fabricating a tapered field plate dielectric for high-voltage semiconductor devices is disclosed. The process may include depositing a thin layer of oxide, depositing a polysilicon hard mask, depositing a resist layer and etching a trench area, performing deep silicon trench etch, and stripping the resist layer. The process may further include repeated steps of depositing a layer of oxide and anisotropic etching of the oxide to form a tapered wall within the trench. The process may further include depositing poly and performing further processing to form the semiconductor device.
US08765603B2
Buffer layer and method of forming the buffer layer, the method including forming a high-k dielectric layer, forming a titanium nitride layer over the high-k dielectric layer, forming a silicon layer on the titanium nitride layer, annealing the silicon layer into the titanium nitride layer to form an annealed silicon layer and forming an n-metal over the high-k dielectric layer.
US08765602B2
A method of forming a metal interconnect structure includes forming a copper line within an interlevel dielectric (ILD) layer; directly doping a top surface of the copper line with a copper alloy material; and forming a dielectric layer over the ILD layer and the copper alloy material; wherein the copper alloy material serves an adhesion interface layer between the copper line and the dielectric layer.
US08765597B2
A line trough and a via cavity are formed within a dielectric layer comprising a fluorosilicate glass (FSG) layer. A fluorine depleted adhesion layer is formed within the line trough and the via cavity either by a plasma treatment that removes fluorine from exposed surfaces of the FSG layer, or by deposition of a substantially fluorine-free dielectric layer. Metal is deposited within the line trough and the via cavity to form a metal line and a metal via. The fluorine depleted adhesion layer provides enhanced adhesion to the metal line compared with prior art structures in which a metal line directly contacts a FSG layer. The enhanced adhesion of metal with an underlying dielectric layer provides higher resistance to delamination for a semiconductor package employing lead-free C4 balls on a metal interconnect structure.
US08765592B2
A method for contacting MOS devices. First openings in a photosensitive material are formed over a substrate having a top dielectric in a first die area and a second opening over a gate stack in a second die area having the top dielectric, a hard mask, and a gate electrode. The top dielectric layer is etched to form a semiconductor contact while etching at least a portion the hard mask layer thickness over a gate contact area exposed by the second opening. An inter-layer dielectric (ILD) is deposited. A photosensitive material is patterned to generate a third opening in the photosensitive material over the semiconductor contact and a fourth opening inside the gate contact area. The ILD is etched through to reopen the semiconductor contact while etching through the ILD and residual hard mask if present to provide a gate contact to the gate electrode.
US08765590B2
A method comprises: forming a semiconductor device on a base substrate, the semiconductor device having a core metal positioned proximate a source and a drain in the base substrate, a work function metal on a portion of the core metal, and a dielectric layer on a portion of the work function metal; forming a metal gate in electrical communication with one of the source and the drain; and implanting an insulator film on the core metal of the semiconductor device. The insulator film on the core metal forms an insulative barrier across the metal gate and between the core metal of the semiconductor device and the source or the drain.
US08765577B2
A method of forming a strained semiconductor material that in one embodiment includes forming a cleave layer in a host semiconductor substrate, and contacting a strain inducing material layer on a surface of a transfer portion of the host semiconductor substrate. A handle substrate is then contacted to an exposed surface of the stress inducing material layer. The transfer portion of the host semiconductor substrate may then be separated from the host semiconductor substrate along the cleave layer. A dielectric layer is formed directly on the transfer portion of the host semiconductor substrate. The handle substrate and the stress inducing material are then removed, wherein the transferred portion of the host semiconductor substrate provides a strained semiconductor layer that is in direct contact with a dielectric layer.
US08765576B2
A method of manufacturing a laminated substrate is provided. The method includes: forming an oxide film on at least a surface of a first substrate having a hardness of equal to or more than 150 GPa in Young's modulus, and then smoothing the oxide film; implanting hydrogen ions or rare gas ions, or mixed gas ions thereof from a surface of a second substrate to form an ion-implanted layer inside the substrate, laminating the first substrate and the second substrate through at least the oxide film, and then detaching the second substrate in the ion-implanted layer to form a laminated substrate; heat-treating the laminated substrate and diffusing outwardly the oxide film.
US08765572B2
A method of fabricating a semiconductor device, in which an interference effect between word lines is substantially reduced or eliminated, includes forming a plurality of gate patterns on a substrate; forming a first insulating layer between the gate patterns, the first insulating layer filling a region between the gate patterns; etching the first insulating layer to remove a portion of the first insulating layer to a predetermined depth; and forming a second insulating layer on the gate patterns and the first insulating layer. A low-dielectric-constant material is formed between the gate patterns.
US08765561B2
A method for fabricating semiconductor device is disclosed. The method includes the steps of: providing a substrate; forming a dummy gate on the substrate; forming a contact etch stop layer on the dummy gate and the substrate; performing a planarizing process to partially remove the contact etch stop layer; partially removing the dummy gate; and performing a thermal treatment on the contact etch stop layer.
US08765558B2
A CMOS structure and a method for fabricating the CMOS structure include within a semiconductor substrate a first gate located over a first active region of a first polarity and a second gate located over a second active region of a second polarity different than the first polarity. The first active region and the second active region are separated by an isolation region. The first gate and the second gate are co-linear, with facing endwalls that terminate over the isolation region. The facing endwalls do not have a spacer located or formed adjacent or adjoining thereto, although sidewalls of the first gate and the second gate do. The CMOS structure may be fabricated using a sequential replacement gate method.
US08765556B2
The present disclosure provides a semiconductor device that includes a semiconductor substrate, a gate structure disposed on a portion of the substrate, and strained structures disposed at either side of the portion of the substrate and formed of a semiconductor material different from the semiconductor substrate. The portion of the substrate is T shaped having a horizontal region and a vertical region that extends from the horizontal region in a direction away from a surface of the substrate.
US08765551B2
According to an example embodiment, a non-volatile memory device includes a semiconductor layer pattern on a substrate, a plurality of gate patterns and a plurality of interlayer insulating layer patterns that are alternately stacked along a side wall of the semiconductor layer pattern, and a storage structure between the plurality of gate patterns and the semiconductor layer pattern. The semiconductor layer pattern extends in a vertical direction from the substrate. The gate patterns are recessed in a direction from a side wall of the interlayer insulating layer patterns opposing the side wall of the semiconductor layer pattern. A recessed surface of the gate patterns may be formed to be vertical to a surface of the substrate.
US08765548B2
Semiconductor devices, capacitors, and methods of manufacture thereof are disclosed. In one embodiment, a method of fabricating a capacitor includes forming a first material over a workpiece, and patterning the first material, forming a first capacitor plate in a first region of the workpiece and forming a first element in a second region of the workpiece. A second material is formed over the workpiece and over the patterned first material. The second material is patterned, forming a capacitor dielectric and a second capacitor plate in the first region of the workpiece over the first capacitor plate and forming a second element in a third region of the workpiece.
US08765541B1
A method to design an IC is disclosed to provide a uniform deposition of strain-inducing composites is disclosed. The method to design the IC comprises, determining a total strain-inducing deposition area on an IC design. Then, the total strain inducing deposition area is compared with a predefined size. A dummy diffusion area is modified to increase the total strain-inducing deposition area, when the total strain-inducing deposition area is below the predefined size. Finally, the strain-inducing deposition area is optimized. A method to manufacture the IC and the IC is also disclosed.
US08765539B2
A semiconductor structure is provided, which includes multiple sections arranged along a longitudinal axis. Preferably, the semiconductor structure comprises a middle section and two terminal sections located at opposite ends of the middle section. A semiconductor core having a first dopant concentration preferably extends along the longitudinal axis through the middle section and the two terminal sections. A semiconductor shell having a second, higher dopant concentration preferably encircles a portion of the semiconductor core at the two terminal sections, but not at the middle section, of the semiconductor structure. It is particularly preferred that the semiconductor structure is a nanostructure having a cross-sectional dimension of not more than 100 nm.
US08765538B2
Provided are three-dimensional semiconductor memory devices and methods of forming the same. The device includes a substrate, conductive patterns stacked on the substrate, and an active pattern penetrating the conductive patterns to be connected to the substrate. The active pattern may include a first doped region provided in an upper portion of the active pattern, and a diffusion-resistant doped region overlapped with at least a portion of the first doped region. The diffusion-resistant doped region may be a region doped with carbon.
US08765537B2
A high-k metal gate electrode is formed with reduced gate voids. An embodiment includes forming a replaceable gate electrode, for example of amorphous silicon, having a top surface and a bottom surface, the top surface being larger than the bottom surface, removing the replaceable gate electrode, forming a cavity having a top opening larger than a bottom opening, and filling the cavity with metal. The larger top surface may be formed by etching the bottom portion of the amorphous silicon at greater temperature than the top portion, or by doping the top and bottom portions of the amorphous silicon differently such that the bottom has a greater lateral etch rate than the top.
US08765535B2
In the method for manufacturing a semiconductor device of the invention, a bonding layer is formed over a substrate, an insulating film and a storage capacitor portion lower electrode are formed over the bonding layer, a single crystal silicon layer is formed over the insulating film, a storage capacitor portion insulating film is formed over the storage capacitor portion lower electrode, a wiring is formed over the storage capacitor portion insulating film, a channel forming region and a low concentration impurity region are formed over the single crystal silicon layer, and a gate insulating film and a gate electrode are formed over the single crystal silicon layer. The storage capacitor portion insulating film is formed by depositing a YSZ film with a single crystal silicon layer used as a base film, whereby the permittivity increases and thus the leakage current from the storage capacitor portion is suppressed.
US08765532B2
A method for forming a field effect device includes forming a gate portion on a silicon-on-insulator layer (SOI), forming first spacer members on the SOI layer adjacent to the gate portion, depositing a layer of spacer material on the SOI layer, the first spacer members, and the gate portion, removing portions of the layer of spacer material to form second spacer members on the SOI layer adjacent to the first spacer members, forming a source region and a drain region on the SOI layer by implanting ions in the SOI layer, and etching to remove the second spacer members.
US08765531B2
A method for manufacturing a metal pad structure of a die is provided, the method including: forming a metal pad between encapsulation material of the die, wherein the metal pad and the encapsulation material are separated from each other by a gap; and forming additional material in the gap to narrow at least a part of the gap.
US08765525B2
A method of manufacture of an integrated packaging system includes: providing a substrate; mounting an integrated circuit on the substrate; mounting an interposer substrate having an interposer pad on the integrated circuit; covering an encapsulant over the integrated circuit and the interposer substrate; forming a hole through the encapsulant aligned over the interposer pad; and placing a conductive connector on and in direct contact with the interposer pad.
US08765522B2
One embodiment is a method for manufacturing a stacked oxide material, including the steps of forming a first oxide component over a base component, causing crystal growth which proceeds from a surface toward an inside of the first oxide component by first heat treatment to form a first oxide crystal component at least partly in contact with the base component, forming a second oxide component over the first oxide crystal component; and causing crystal growth by second heat treatment using the first oxide crystal component as a seed to form a second oxide crystal component.
US08765520B2
A photovoltaic electrode is made by the following steps: (a) depositing on a substrate a dispersion comprising powdered semiconductor particles in a dispersion medium; (b) removing the majority of the dispersion medium to leave the powdered semiconductor particles in a deposition layer on the substrate; (c) creating a plasma using microwave energy excitation; (d) exposing the deposition layer to said microwave-excited plasma for a sufficient time to sinter the nanoparticles thereby adhering them to the substrate; and (e) absorbing a dye into said sintered deposition layer. The electrode thus obtained exhibits improved performance relative to conventional sintered electrodes.
US08765514B1
A center region of conductive material/s may be disposed or “sandwiched” between transition regions of relatively lower conductivity materials to provide substantially low defect density interfaces for the sandwiched material. The center region and surrounding transition regions may in turn be disposed or sandwiched between dielectric insulative material to form a sandwiched and transitioned device structure. The center region of such a sandwiched structure may be implemented, for example, as a device layer such as conductive microbolometer layer for a microbolometer detector structure.
US08765510B2
A photonic device comprises a substrate and a dielectric material including two or more openings that expose a portion of the substrate, the two or more openings each having an aspect ratio of at least 1. A bottom diode material comprising a compound semiconductor material that is lattice mismatched to the substrate occupies the two or more openings and is coalesced above the two or more openings to form the bottom diode region. The device further includes a top diode material and an active diode region between the top and bottom diode materials.
US08765502B2
A method of forming an integrated photonic semiconductor structure having a photodetector device and a CMOS device may include depositing a dielectric stack over the photodetector device such that the dielectric stack encapsulates the photodetector. An opening is etched into the dielectric stack down to an upper surface of a region of an active area of the photodetector. A first metal layer is deposited directly onto the upper surface of the region of the active area via the opening such that the first metal layer may cover the region of the active area. Within the same mask level, a plurality of contacts including a second metal layer are located on the first metal layer and on the CMOS device. The first metal layer isolates the active area from the occurrence of metal intermixing between the second metal layer and the active area of the photodetector.
US08765497B2
A method includes placing a plurality of bottom units onto a jig, wherein the plurality of bottom units is not sawed apart and forms an integrated component. Each of the plurality of bottom units includes a package substrate and a die bonded to the package substrate. A plurality of upper component stacks is placed onto the plurality of bottom units, wherein solder balls are located between the plurality of upper component and the plurality of bottom units. A reflow is performed to join the plurality of upper component stacks with respective ones of the plurality of bottom units through the solder balls.
US08765496B2
Methods and systems for measuring a characteristic of a substrate or preparing a substrate for analysis are provided. One method for measuring a characteristic of a substrate includes removing a portion of a feature on the substrate using an electron beam to expose a cross-sectional profile of a remaining portion of the feature. The feature may be a photoresist feature. The method also includes measuring a characteristic of the cross-sectional profile. A method for preparing a substrate for analysis includes removing a portion of a material on the substrate proximate to a defect using chemical etching in combination with an electron beam. The defect may be a subsurface defect or a partially subsurface defect. Another method for preparing a substrate for analysis includes removing a portion of a material on a substrate proximate to a defect using chemical etching in combination with an electron beam and a light beam.
US08765495B1
A method of forming a pattern of doped region includes the following steps. At first, a device layout pattern including a gate layout pattern and a doped region layout pattern is provided to a computer system. Subsequently, the device layout pattern is split into a plurality of sub regions, and the sub regions have different pattern densities of the gate layout pattern. Then, at least an optical proximity correction (OPC) calculation is respectively performed on the doped region layout pattern in each of the sub regions to respectively form a corrected sub doped region layout pattern in each of the sub regions. Afterwards, the corrected sub doped region layout patterns are combined to form a corrected doped region layout pattern, and the corrected doped region layout pattern is outputted onto a mask through the computer system.
US08765492B2
This method of manufacturing a silicon wafer has a step of preparing a wafer, in which a surface of the silicon wafer is surface-treated, a step of setting stress, in which the stress S (MPa) subjected on the wafer is set, a step of inspecting, in which a defect on a surface of the wafer is inspected, and a step of determining, in which the wafer is evaluated if the wafer satisfies a criterion. In this method, it is possible to manufacture a wafer with cracking resistance even if it is subjected to a millisecond annealing by the FLA annealing treatment.
US08765490B2
The present disclosure describes a semiconductor MRAM device and a manufacturing method. The device reduces magnetic field induction “interference” (disturbance) phenomenon between adjacent magnetic tunnel junctions when data is written and read. This semiconductor MRAM device comprises a magnetic tunnel junction unit and a magnetic shielding material layer covering the sidewalls of the magnetic tunnel junction unit. The method for manufacturing a semiconductor device comprises: forming a magnetic tunnel junction unit, depositing an isolation dielectric layer to cover the top and the sidewall of the magnetic tunnel junction unit, and depositing a magnetic shielding material layer on the isolation dielectric layer.
US08765487B2
A method is taught for the accurate determination of the premature rupture of membranes (PROM), defined as spontaneous rupture of membranes before the onset of uterine contractions. More specifically, a lateral flow assay strip tests for at least two antigens to greatly limit or eliminate the possibility of false negatives. A built in timer in the cassette holding the lateral flow assay further increases the accuracy of the test. A collection buffer vial with self-contained shipping and dropper caps and built in stand is also taught.
US08765482B2
A test strip with a sample chamber is secured to a meter. The sample chamber in the portion of the test strip that extends out of the meter is illuminated by transmitting light from a light source inside the meter internally through the test strip towards the sample chamber. By way of analogy, the test strip acts in a fashion similar to a fiber optic cable or optical wave guide by transmitting the light from the meter to the remotely located sample chamber that extends outside the meter. The user is then able to easily see the sample chamber of the test strip in dark conditions so that the user is able to readily align the sample chamber with the drop of fluid on the skin as well as view the sample chamber in order to ensure proper filling. The light also illuminates a test strip slot into which the test strip is inserted.
US08765479B1
The present disclosure provides methods to predict the risk of CHD and/or clinical manifestations of CHD in a subject. In one embodiment, the method involves measuring the levels or concentration of apo A1, a subclass of HDL, HDL3, or a combination of the foregoing. The methods of the present disclosure are particularly useful when the subject has reached target levels of one or more lipoproteins, such as, but not limited to, LDL or HDL or subclass of the foregoing.
US08765477B2
A method for measuring the real hot-spot temperature in an electric apparatus containing an oil, such as an electric power transformer. The electric apparatus is operated under predetermined and modifiable operating conditions. This method comprises the use of one or several chemical compounds or tracers present and soluble in the oil. Each tracer may transform, at a given temperature, in order to form a residue, such as a soluble gas. From the presence of the residue in the oil, the operator will be able to determine under which predetermined operating condition the hot-spot has been reached and to deduce the hot-spot for a given condition. Among different used compounds, there are diazoic compounds, carbonyl metals, colorants, pigments, liquid crystals and albumins. The method also allows to check the quality of the apparatus on the market and to estimate its life span.
US08765474B2
An automatic analyzer which assures uniformity in mixing effects regardless of sample quantity and test item and thus produces analysis results with high repeatability. The automatic analyzer includes a device for adding a conditioning liquid into a reaction chamber so that the quantity of liquid in the reaction chamber becomes a predetermined quantity prior to being mixed. The conditioning liquid may be a diluent or physiological saline as used for dilution of a sample or any other special liquid that adjusts the properties such as viscosity, surface tension, etc. of liquid to be mixed.
US08765472B2
The present invention relates to methods and devices to obtain multicellular arrangements in stable, stationary and reproducible spatial configuration, and optionally with controlled internal cell organization, methods for preparing such devices, methods for studying the cells' shapes, the cells' architectures, the cells' mechanical equilibrium, the cell-cell interaction, the cell movement and migration, the cell differentiation, the global internal cells' organizations, the cells' polarities and division, and/or any function of cells, methods for screening compounds of interest which enhance or inhibit specific cell functions.
US08765469B2
A method for preparing lymphocytes characterized in that the method comprises the step of carrying out expansion in the presence of (a) fibronectin, a fragment thereof or a mixture thereof, (b) a CD3 ligand, and (c) a CD28 ligand.
US08765462B2
Compositions and methods for delivering immune modulatory molecules to result in a therapeutic effect are disclosed. The compositions and methods use stably integrating lentiviral delivery systems. The methods are useful for therapeutically and prophylactically treating cancer such as leukemia.
US08765460B2
A photobioreactor system for mass production of microorganisms is disclosed. Water with microorganisms suspended therein is sprayed through a nozzle to create droplets. These droplets have a high surface area to volume ratio enabling efficient light transfer and gas diffusion. The water may also be passed through channels between two transparent plates, wherein superior mixing is achieved along with a high surface to volume ratio. The water is preferably circulated through a dark holding tank Active and passive flashing lights of different wavelengths are used to promote growth of the microorganisms when the water is sprayed and/or passing through the transparent plates.
US08765459B2
The invention provides systems and methods for manipulating biological systems, for example to elicit a more desired biological response from a biological sample, such as a tissue, organ, and/or a cell. In one aspect, the invention operates by efficiently searching through a large parametric space of stimuli and system parameters to manipulate, control, and optimize the response of biological samples sustained in the system. In one aspect, the systems and methods of the invention use at least one optimization algorithm to modify the actuator's control inputs for stimulation, responsive to the sensor's output of response signals. The invention can be used, e.g., to optimize any biological system, e.g., bioreactors for proteins, and the like, small molecules, polysaccharides, lipids, and the like. Another use of the apparatus and methods includes is for the discovery of key parameters in complex biological systems.
US08765458B2
The invention provides coated sensors for detecting the presence of analytes. The sensor comprises one or more fluorescent sources, such as one or more quantum dots or one or more fluorescent dyes, a polymeric matrix, a surface coating, and one or more analyte sensing components. The surface coating may be a conformal polymeric film, permeable to the analyte, which may be deposited via a solventless process such as initiated chemical vapor deposition or photoinitiated chemical vapor deposition. The surface coating may increase the biocompatibility of the sensor, reduce nonspecific protein adsorption, and/or sequester functional sensor components within the sensor. The invention also provides methods for detecting the presence of an analyte with coated sensors of the invention.
US08765448B2
Methods and means are provided for the exact exchange in eukaryotic cells, such as plant cells, of a target DNA sequence for a DNA sequence of interest through homologous recombination, whereby the selectable or screenable marker used during the homologous recombination phase for temporal selection of the gene replacement events can subsequently be removed without leaving a foot-print employing a method for the removal of a selected DNA flanked by two nucleotide sequences in direct repeats.
US08765437B2
This invention provides compositions of active highly phosphorylated human N-acetylgalactosamine-6-sulfatase (GALNS), and pharmaceutical compositions and formulations thereof, methods of producing and purifying GALNS, and its use in the diagnosis, prophylaxis, or treatment of diseases and conditions, including particularly lysosomal storage diseases that are caused by, or associated with, a deficiency in the GALNS enzyme, e.g., Mucopolysaccharidosis IVa (MPS IVa or Morquio A syndrome).
US08765426B2
Zymomonas is unable to synthesize pantothenic acid and requires this essential vitamin in growth medium. Zymomonas strains transformed with an operon for expression of 2-dehydropantoate reductase and aspartate 1-decarboxylase were able to grow in medium lacking pantothenic acid. These strains may be used for ethanol production without pantothenic acid supplementation in seed culture and fermentation media.
US08765422B2
Disclosed are methods and compositions related to ONC-T18, D4-desaturases, D5 elongases, their isolation, characterization, production, identification, and use for fatty acid production, as well as organisms containing these compositions and organisms expressing them.
US08765412B2
The invention relates to a method of preparing heteromultimeric polypeptides such as bispecific antibodies, bispecific immunoadhesins and antibody-immunoadhesin chimeras. The invention also relates to the heteromultimers prepared using the method. Generally, the method provides a multispecific antibody having a common light chain associated with each heteromeric polypeptide having an antibody binding domain. Additionally the method further involves introducing into the multispecific antibody a specific and complementary interaction at the interface of a first polypeptide and the interface of a second polypeptide, so as to promote heteromultimer formation and hinder homomultimer formation; and/or a free thiol-containing residue at the interface of a first polypeptide and a corresponding free thiol-containing residue in the interface of a second polypeptide, such that a non-naturally occurring disulfide bond is formed between the first and second polypeptide. The method allows for the enhanced formation of the desired heteromultimer relative to undesired heteromultimers and homomultimers.
US08765407B2
An L-amino acid is produced by culturing an L-amino acid-producing bacterium which belongs to the Enterobacteriaceae family and which has been modified so that the activity of an iron transporter is increased by enhancing expression of one or more genes of the following genes: tonB gene, fepA gene, and fecA.
US08765395B2
A presence/absence test for Staphylococcus aureus (S. aureus) involves placing a first generation test sample in a solution that will clot in the presence of S. aureus. The solution contains components that will selectively grow S. aureus and also contains clotting factors that will react with S. aureus, if S. aureus is present in the sample, to clot the solution. Examples of specimen samples that can be tested include nasal swabs and lesion swabs, among others. The test can also be modified to detect the presence or absence of methicillin resistant S. Aureus (MRSA).
US08765389B2
The invention relates to the identification of genetic products expressed in association with tumors and to coding nucleic acids for said products. The invention also relates to the therapy and diagnosis of diseases in which the genetic products are aberrantly expressed in association with tumors, proteins, polypeptides and peptides which are expressed in association with tumors and to the coding nucleic acids for said proteins, polypeptides and peptides.
US08765385B2
The disclosure provides, among other aspects, neutralizing antibodies and portions thereof that bind to ActRIIB and uses for same.
US08765372B2
The invention relates to diagnostic methods to predict whether a subject is predisposed for acquiring a disease or to predict the therapy responsiveness of an individual patient. Provided is a method for determining whether a subject is predisposed for developing an autoimmune disease, comprising determining in a sample isolated from said subject the amount of intact genes, or gene products thereof, of the FcγRII/FcγRIII gene cluster, said gene cluster comprising the FCGR2C, FCGR3A, FCGR2A and FCGR3B genes encoding an activating FcγR, and FCGR2B encoding an inhibitory FcγR; and correlating said amount to the amount observed in a healthy population. Also provided is a method to predict the responsiveness of a subject to therapy with intravenous immunoglobulin (IVIg) therapy or a monospecific biological, such as a humanized or human monoclonal antibody or a chimeric molecule, comprising the C-terminal Fc-tail of IgG.
US08765370B2
A method for screening cells with high level expression of a target protein is disclosed. The method includes introducing into a plurality of host cells a DNA construct that encodes both a target protein and an inhibitor to an endogenous selectable marker in the host cells, screening host cells harboring the DNA construct for the expression of the endogenous selectable marker, and isolating cells with reduced expression of the selectable marker. Also disclosed is a DNA construct configured to express both the target protein and the inhibitor inside the host cell.
US08765362B2
According to one embodiment, a patterning method includes exposure-transferring a plurality of first island pattern images and a plurality of second island pattern images onto a resist film, each of the plurality of first island pattern images having a configuration having a contour line or a major axis extending in a third direction, the plurality of first island pattern images having a staggered arrangement, each of the plurality of second island pattern images having a configuration having a contour line or a major axis extending in a fourth direction, the plurality of second island pattern images having a staggered arrangement, the first island pattern images and the second island pattern images being continuous in the first direction by a portion of each of the second island pattern images overlapping one of the first island pattern images.
US08765358B2
A water-soluble resin composition for forming fine patterns comprising water-soluble polymer represented by Chemical Formula 1 as below and the first water-soluble solvent, is coated and heated on a photoresist layer having at least one contact hole to reduce a size of the at least one contact hole. (In Chemical Formula 1, each of R1, R2, R3 and R5 independently represents an alkyl group of C1-30 or an cyclo alkyl group of C3-30 which respectively have one selected from the group consisting of hydrogen, an ether group, an ester group, a carbonyl group, an acetal, an epoxy group, a nitril group, an amine group, and an aldehyde group; each of R4, R6, R7 and R8 independently represents hydrogen or a methyl group; n represents an integer of 0 to 5; a represents a real number of 0.05 to 0.5; each of b, c and d respectively represents a real number of 0 to 0.7; and a+b+c+d=1).
US08765355B2
A radiation sensitive resin composition includes a first polymer having a group represented by a following formula (1), and a radiation sensitive acid generator. n is an integer of 2 to 4. X represents a single bond or a bivalent organic group. A represents a (n+1) valent linking group. Each Q independently represents a group that includes an alkali-dissociable group.
US08765339B2
The presently disclosed embodiments relate generally to layers that are useful in imaging apparatus members and components, for use in electrophotographic, including digital printing, apparatuses. More particularly, the embodiments pertain to an improved electrophotographic imaging member comprising a charge transport layer comprising a novel combination of a tetraaryl polycarbonate copolymer binder and perfluorinated fillers. The present charge transport layer provides reduced wear rate and long service life.
US08765332B2
The invention provides a green curable composition including a colorant in an amount of 47.5% by mass or more with respect to the total solid content of the green curable composition, the colorant containing a halogenated copper phthalocyanine pigment and a barbituric acid derivative yellow pigment at a ratio of from 6/4 to 3/7 (halogenated copper phthalocyanine pigment/barbituric acid derivative yellow pigment); a colored pattern formed from the green curable composition; a color filter including the colored pattern; a solid-state image sensor including the color filter; and a method of producing the color filter.
US08765324B2
The present invention relates a method for manufacturing a fuel cell. An object of the present invention is to provide a method for manufacturing a membrane electrode assembly capable of solving an electrical connection problem caused by uneven tube lengths and improving an output, and a solid polymer electrolyte fuel cell. The method for manufacturing the membrane electrode assembly of the present invention includes a seed catalyst layer forming process (1), a CNT growing process (2), a CNT entanglement promoting process (3), a catalyst carrying process (4), an ionomer arranging process (5), and a transferring (MEA conversion) process (6). According to the present invention, entanglement of adjacent CNTs can be promoted by the CNT entanglement promoting process (3) and therefore the electrical connection of the CNTs can be ensured. Thus, the output of the cell can be improved.
US08765321B2
A transition metal nitride is obtained by a nitriding treatment of a surface of a base material including a transition metal or an alloy of the transition metal, and the transition metal nitride has a crystal structure of an M4N type and a crystal structure of an ε-M2˜3N type, and is formed over a whole area of the surface of the base material and continuously in a depth direction from the surface.
US08765320B2
A fuel cell assembly (110, 210) has a plurality of fuel cell component elements (112) extending between a pair of end plates (114, 115) to form a stack (116), and plural reactant gas manifolds (120, 220; 122, 222; 124, 224; 126, 226) mounted externally of and surrounding the stack, in mutual, close sealing relationship to prevent leakage of reactant gas in the manifolds to the environment external to the manifolds. The reactant gas manifolds are configured and positioned to maximize sealing contact with smooth surfaces of the stack and the manifolds. One embodiment is configured for an oxidant reactant manifold (120, 124) to overlie the region where the fuel reactant manifold (122, 126) engages the stack. Another embodiment further subdivides an oxidant reactant manifold to include a liquid flow channel (270, 274), which liquid flow channel overlies the region where the fuel reactant manifold (122, 126) engages the stack.
US08765297B2
An Advanced Graphite, with a lower degree of ordered carbon domains and a surface area greater than ten times that of typical battery grade graphites, is used in negative active material (NAM) of valve-regulated lead-acid (VRLA) type Spiral wound 6V/25 Ah lead-acid batteries. A significant and unexpected cycle life was achieved for the Advanced Graphite mix where the battery was able to cycle beyond 145,000 cycles above the failure voltage of 9V in a non-stop, power-assist cycle-life test. Batteries with Advanced Graphite also showed increased charge acceptance power and discharge power compared to control groups.
US08765280B2
A battery pack for use with a battery-driven power tool includes three battery cells in which two out of three are arranged horizontally in parallel to and in alignment with each other in a lower case and the remaining one battery cell is vertically arranged in an upper case. The upper case of the battery pack is inserted, in use, into a battery pack receiving space formed in the grip portion of a power tool. Therefore, the grip portion can be made thin and usability of the power tool is enhanced.
US08765258B2
The present invention provides a cover film for a printed circuit board. The cover film includes an adhesive layer; a core layer made of a polymer; and a composite material layer formed on the core layer, comprising epoxy resin, a black material selected from the group consisting of a black pigment, carbon powder, nano carbon tube and a combination thereof, and an additive selected from the group consisting of titanium dioxide, boron nitride, barium sulfate and a combination thereof, wherein the core layer is disposed between the adhesive layer and the composite material layer, and the adhesive layer and the composite material layer have the same thickness or have a thickness difference being no more than 15 micro meters. The cover film of the preset invention is capable of shielding circuit patterns and has great folding endurance, and is thus applicable to flexible printed circuit boards.
US08765199B2
The present invention provides processes for producing a brewers wort comprising forming a mash from a grist, and contacting said mash with a pullulanase.
US08765195B2
Embodiments of the invention generally relate to methods and supplements for increasing sex steroids and human growth hormone in a human being.
US08765184B2
The present invention relates to a method for preparing solid pharmaceutical compositions comprising fine particles of at least one active substance, dispersed on and (or) within a divided solid. This method is characterized in that a solution is formed which comprises at least one active substance in a fluid at supercritical pressure, said solution then being expanded in a chamber under temperature and pressure conditions for which a part of said fluid is in the liquid state at the time of the expansion, said fluid thus expanded being brought into contact with a divided solid in said chamber.
US08765181B2
The present invention provides a nano-micellar preparation containing vinca alkaloids antitumor agent for intravenous injection, which cincludes a therapeutically effective amount of vinca alkaloids antitumor agent (vinblastine, vincristine, vindesine and vinorelbine), a phosphatide derivatized with polyethylene glycol, together with pharmaceutically acceptable adjuvants. The preparation is prepared by encapsulating the medicament with a nano-micelle to obtain the nano-micellar preparation containing vinca alkaloids antitumor agent for injection. The vinca alkaloids antitumor agent and the phosphatide derivatized with polyethylene glycol form a nano-micelle with a highly uniform particle size. In the micelle, the hydrophobic core of encapsulated medicament is surrounded by polyethylene glycol molecules to form a hydrophilic protective layer, so that the medicament is prevented from contacting with the enzymes and other protein molecules in blood and being recognized and phagocytozed by reticuloendothelial system in body, and the circulation time in vivo of the micelle is prolonged.
US08765172B2
Novel acoustically sensitive drug carrying particles comprising non-lamellar forming lipids are disclosed, as well as uses and methods thereof. The drug carrying particles accumulate in the diseased target tissue and efficiently release their payload upon exposure to acoustic energy.
US08765169B2
The present invention relates to compositions and methods for tissue regeneration, particularly for treating skin lesions such as wounds. In one aspect, the invention provides wound healing composition characterized by the higher expression levels of phenotypic marker genes such as apolipoprotein D, matrix metalloprotease (2), collagen 3a1 and smooth muscle actin than the housekeeping gene ribosomal protein L32. The compositions and methods of the invention are useful especially for assisting the process of wound healing, particularly chronic open lesions that are slow to heal or resistant to healing.
US08765156B2
A topical composition of improved spreadability and aesthetical appeal is provided, which contains inorganic particulates in combination with an alkoxylated diphenylacrylate compound. Preferably, the topical composition is a sunscreen composition that contains inorganic or physical sunscreen agents in combination with an alkoxylated α-cyanodiphenylacrylate compound, which is characterized by improved photo-protection of the skin and is effective in preventing/reducing photo-damage of the skin upon exposure to sunlight or other sources of light in the ultraviolet (UV), visible, and infrared (IR) ranges.
US08765147B2
The present disclosure relates to endophytic fungi from higher plants such as a Pteromischum sp. plant, and to extracts and compounds from such fungi that have desirable biological activities, such as antifungal and immunosuppressive activities. The present disclosure further relates to compositions comprising such extracts and compounds, as well as methods of making and using the compositions.
US08765132B2
The invention relates to neutralizing antibodies, and antibody fragments thereof, having high potency in neutralizing hCMV, wherein said antibodies and antibody fragments are specific for one, or a combination of two or more, hCMV gene UL products. The invention also relates to immortalized B cells that produce, and to epitopes that bind to, such antibodies and antibody fragments. In addition, the invention relates to the use of the antibodies, antibody fragments, and epitopes in screening methods as well as in the diagnosis, prevention, and therapy of disease.
US08765129B2
Monoclonal antibodies are provided that selectively bind human hepcidin-25 and are characterized as having high affinity for human hepcidin-25 and strong human mature hepcidin neutralizing properties. The antibodies of the invention are useful therapeutically for increasing serum iron levels, reticulocyte count, red blood cell count, hemoglobin, and/or hematocrit in a human and for the treatment and diagnosis of mature hepcidin-promoted disorders such as anemia, in a human subject.
US08765127B2
Uses of BMP-1 isoforms for diagnosing and treating defects and disorders of bone and soft tissues are described. Also described is a newly isolated variant of the BMP-1 isoform BMP-1-3.
US08765120B2
The present invention provides muscle-derived cells, preferably myoblasts and muscle-derived stem cells, genetically engineered to contain and express one or more heterologous genes or functional segments of such genes, for delivery of the encoded gene products at or near sites of musculoskeletal, bone, ligament, meniscus, cartilage or genitourinary disease, injury, defect, or dysfunction. Ex vivo myoblast mediated gene delivery of human inducible nitric oxide synthase, and the resulting production of nitric oxide at and around the site of injury, are particularly provided by the invention as a treatment for lower genitourinary tract dysfunctions. Ex vivo gene transfer for the musculoskeletal system includes genes encoding acidic fibroblast growth factor, basic fibroblast growth factor, epidermal growth factor, insulin-like growth factor, platelet derived growth factor, transforming growth factor-1, transforming growth factor-a, nerve growth factor and interleukin-1 receptor antagonist protein (IRAP), bone morphogenetic protein (BMPs), cartilage derived morphogenetic protein (CDMPs), vascular endothelial growth factor (VEGF), and sonic hedgehog proteins.
US08765110B2
A composition comprising: at least one alkoxysilane having at least one solubilizing functional group and at least one amino substituent; at least one glycosaminoglycan chosen from hyaluronic acid; water; optionally, at least one auxiliary ingredient; and optionally, at least one volatile solvent.
US08765109B2
A cosmetic comprising an amino acid oil gelling agent, a polyamide resin and a monoester, wherein the amino acid oil gelling agent is one or more selected from dibutyl ethylhexanoyl glutamide and dibutyl lauroyl glutamide, and wherein said monoester is one or more selected from a monoester having a C9 to C24 linear chain or branched chain fatty acid moiety and/or a C9 to C24 linear chain or branched chain alcohol moiety, and said monoester is 20-80 mass % of the cosmetic. Cosmetic products, and methods for making and preparing cosmetics.
US08765106B2
Human sebum mimetics and methods for producing human sebum mimetics are provided. In one exemplary embodiment, a human sebum mimetic comprises a wax ester derived from interesterification of refined botanical oil comprising palmitoleic acid and refined jojoba oil, a phytosterol, phytosqualene, and/or phytosteryl macadamiate. Method for producing a human sebum mimetic comprises mixing refined macadamia oil and refined jojoba oil, interesterifying the refined macadamia oil and the refined jojoba oil, adding a phytosterol, adding phytosteryl macadamiate, and adding phytosqualene after the interesterifying.
US08765103B2
The present invention is directed to a cosmetic composition comprising an effect pigment based on a glass flake as a substrate with a coating, said coating comprising at least one layer of at least one high refractive material, said material having a refractive index of at least 1.8, and/or a semitransparent metal coating wherein said glass flakes comprising the following composition: 65-75 wt.-% silicon oxide, preferably SiO2 2-9 wt.-% aluminium oxide, preferably Al2O3 0.0-5 wt.-% calcium oxide, preferably CaO 5-12 wt.-% sodium oxide, preferably Na2O 8-15 wt.-% boron oxide, preferably B2O3 0.1-5 wt.-% titanium oxide, preferably TiO2 0.0-5 wt.-% zirconium oxide, preferably ZrO2 based on the weight of said glass flakes. The invention is also directed to the use of the cosmetic composition.
US08765100B2
A pharmaceutical dosage form adapted to supply a medicament to the oral cavity for buccal, sublingual or gingival absorption of the medicament which contains an orally administerable medicament in combination with an effervescent for use in promoting absorption of the medicament in the oral cavity. The use of additional pH adjusting substance in combination with the effervescent for promoting the absorption of drugs is also disclosed.
US08765084B2
Several embodiments of high-efficiency catalytic converters and associated systems and methods are disclosed. In one embodiment, a catalytic converter for treating a flow of exhaust gas comprising a reaction chamber, a heating enclosure enclosing at least a portion of the reaction chamber, and an optional coolant channel encasing the heating enclosure. The reaction chamber can have a first end section through which the exhaust gas flows into the reaction chamber and a second end section from which the exhaust gas exits the reaction chamber. The heating enclosure is configured to contain heated gas along the exterior of the reaction chamber, and the optional coolant channel is configured to contain a flow of coolant around the heating enclosure. The catalytic converter can further include a catalytic element in the reaction chamber.
US08765082B2
Processes for using a combination of carbon dioxide and oxygen in the dehydrogenation of hydrocarbons are provided. A hydrocarbon feedstock, carbon dioxide and oxygen are fed to an oxidative dehydrogenation reactor system containing one or more catalysts that promote dehydrogenation of the hydrocarbon feedstock to produce a dehydrogenated hydrocarbon product. The processes of the present invention may be used, for example, to produce styrene monomer by dehydrogenation of ethylbenzene using carbon dioxide and oxygen as oxidants.
US08765080B1
A tester for testing for explosives comprising a body, a lateral flow swab unit operably connected to the body, a explosives detecting reagent contained in the body, and a dispenser operatively connected to the body and the lateral flow swab unit. The dispenser selectively allows the explosives detecting reagent to be delivered to the lateral flow swab unit.
US08765076B2
The present technology provides for a microfluidic substrate configured to carry out PCR on a number of polynucleotide-containing samples in parallel. The substrate can be a single-layer substrate in a microfluidic cartridge. Also provided are a method of making a microfluidic cartridge comprising such a substrate. Still further disclosed are a microfluidic valve suitable for use in isolating a PCR chamber in a microfluidic substrate, and a method of making such a valve.
US08765075B2
In one embodiment, the invention is to a dry reagent composition configured as a solute to be dissolved into whole-blood prior to a whole-blood immunoassay, the dry reagent composition comprising: goat IgG, mouse IgG, dextran, a buffer, proclin, and sodium chloride in a support matrix. In another embodiment, the invention is to a dry reagent composition configured as a solute to be dissolved into whole-blood prior to a whole-blood immunoassay, the dry reagent composition comprising dextran and a salt in a support matrix.
US08765071B2
Disclosed is a device for generating a volume of gas from solid and liquid generates. In one particular embodiment, a volume of nitrogen gas is generated by combining the output of Sodium Azide and liquid nitrogen. A vacuum is initially maintained about the liquid nitrogen container by way of a dewar jacket. The present disclosure also relates to a method of manufacturing the disclosed gas generating device.
US08765068B2
A honeycomb structural body has a honeycomb body and a pair of electrodes. The honeycomb body has a cell formation part and an outer skin part of a cylindrical hollow shape. The electrodes are formed on an outer peripheral surface of the outer skin part so that the electrodes face to each other in a diameter direction of the honeycomb body. Each of the electrodes has a reference electrode part formed at a central part of the electrode and one or more outside electrode parts formed at both ends of the reference electrode part. The reference electrode parts of the electrode face to each other. The outside electrode parts of the electrodes face to each other. An electrical resistivity of the reference electrode part is smaller than an electrical resistivity of each of the outside electrode parts in each of the electrodes.
US08765065B2
The present invention relates to a process using ultrasonic cutting for the preparation of an oral delivery device comprising a core which includes a pharmaceutically active agent covered by an outer coating which includes one or more openings communicating from the exterior of the device toward the core.
US08765063B1
An air freshener cartridge with mounting that includes a housing with a mounting clip configured to releasably engage with an extant air vent cover to removably secure the air freshener cartridge with mounting thereto, the air cartridge with mounting oriented in a position normal the direction of airflow issuing through said vent.
US08765055B2
Bubble traps for removing bubbles from a stream of liquid and flexible containers comprising such bubble traps are disclosed. The bubble trap includes a containment chamber fluidly coupled to an outlet conduit. At least one grate is disposed between the containment chamber and the outlet conduit. The at least one grate includes a plurality of grate inlets formed in a grate wall and fluidly coupled to the outlet conduit with a plurality of grate conduits such that the containment chamber is fluidly coupled to the outlet conduit. The grate traps bubbles entrained in the stream of liquid flowing from the containment chamber to the outlet conduit in the containment chamber when the bubbles are greater than or equal to a diameter of the grate inlets.
US08765049B2
A method of making ceramic articles includes compounding ceramic precursor batch components that include hydrous clay. The hydrous clay includes particle components having a platy geometry. The crystallite size of the platy hydrous clay particle components is greater than a predetermined amount. Controlling such crystallite size can result in reduced shrinkage of green ware during the clay dehydroxylation stage of firing.
US08765044B2
A method of making a masonry block employing a mold assembly having a plurality liner plates each having a major surface that together form a mold cavity having an open top and an open bottom, wherein at least one liner plate is moveable between a retracted position and a desired extended position within the mold cavity. The method includes providing a negative of a desired texture on the major surface of the moveable liner plate, moving the moveable liner plate to a retracted position, closing the bottom of the mold cavity by positioning a pallet below the mold assembly, filling the mold cavity with dry cast concrete via the open top, vibrating the mold assembly and dry cast concrete therein, and moving the moveable liner plate to a desired extended position during the vibrating.
US08765038B2
A method of feeding a composite molten resin capable of easily forming a multi-kind-multi-layer preform. An apparatus for feeding the composite molten resin has a nozzle portion which includes an outer discharge port in which an outermost annular flow path through which a main layer-forming molten resin flows, meets an outer annular flow path through which a sub-layer-forming molten resin flows inside of the outermost annular flow path; and an inner discharge port in which a shell layer-forming molten resin annularly flowing inside of the outer conflux path, meets the core layer-forming molten resin flowing inside the shell layer; the outer discharge port and the inner discharge port being arranged in this order from the downstream toward the upstream in a direction in which the molten resins flow; wherein provision is made of a shaft-like opening/closing valve for opening and closing the inner discharge port, and a gear pump for intermittently discharging the sub-layer-forming molten resin.
US08765035B2
A process for manufacturing a self-extinguishing cable including at least one transmissive element and at least one flame-retardant coating in a position radially external to the at least one transmissive element, wherein the at least one coating includes an expanded flame-retardant polymeric material having (a) at least one expandable polymer; (b) at least one expanding agent; (c) at least one flame-retardant inorganic filler, in an amount of 100 parts by weight of 250 parts by weight with respect to 100 parts by weight of the at least one expandable polymer. The process includes the following steps: (i) feeding the flame-retardant polymeric material to an extruding apparatus, therein melting and mixing it; (ii) passing the flame-retardant polymeric material obtained in step (i) through at least one static mixer; and (iii) depositing by extrusion the flame-retardant polymeric material obtained in step (ii) onto the at least one transmissive element conveyed to the extruding apparatus.
US08765028B2
Provided are a composition for an oxide semiconductor, a method of preparing the composition, methods of forming an oxide semiconductor thin film and an electronic device using the composition. The composition for an oxide semiconductor includes a tin compound, a zinc compound, and a low electronegativity metal compound containing a metal with an electronegativity lower than zinc.
US08765027B2
A polymer composition comprises at least one substantially non-conductive polymer binder and at least first and second electrically conductive fillers. The first electrically conductive filler is comprised of particles having avoid-bearing structure; and the second electrically conductive filler is comprised of particles which are acicular in shape.
US08765026B2
A tablet for vapor deposition characterized in that on a fracture surface of an indium oxide sintered body, the percentage of crystal grains having a grain diameter corresponding to a highest peak is 20% or less. The tablet is produced by: mixing indium oxide powder and cerium oxide powder, and subjecting the mixture to a heat treatment at 1300° C. to 1550° C. to calcine; mixing an uncalcined indium oxide powder and/or an uncalcined cerium oxide powder with the obtained calcined powder such that the ratio of the calcined powder is 50% to 80% by mass, followed by granulation; and molding the obtained granulated powder, thereby forming a molded body, and then sintering the molded body at a temperature which is 1100° C. to 1350° C., and which is lower than the temperature of the heat treatment on the calcined powder in the first step by 20° C. or more.
US08765025B2
A metal nanoparticle composition includes an organic-stabilized metal nanoparticle and a solvent in which the solvent selected has the following Hansen solubility parameters: a dispersion parameter of about 16 MPa0.5 or more, and a sum of a polarity parameter and a hydrogen bonding parameter of about 8.0 MPa0.5 or less. The metal nanoparticle composition is suitable for printing conductive lines that are uniform, smooth and narrow on various substrate surfaces. The metal nanoparticle composition is able to form printed conductive features having a coffee ring effect ratio of about 1.2 to about 0.8, a surface roughness of about 15 or less and a line width of about 200 microns or less.
US08765023B2
The present invention relates to a composition for preparing a separator for an electrochemical device, a method preparing a separator for an electrochemical device, and an electrochemical device having a separator prepared therefrom, more particularly, a composition for preparing a separator for an electrochemical device, comprising a polyolefin, a first diluent, and a second diluent, wherein an interaction energy between the first diluent and the second diluent is in the range of 2 to 3.5 cal/cm3, a method preparing a separator for an electrochemical device using the composition, and an electrochemical device having a separator prepared therefrom. In accordance with the present invention, the pore size of a polyolefin separator can be suitably controlled into a size desired by a user, and the high-temperature stability and mechanical property of the separator can be remarkably improved, thereby enhancing the life time and stability of an electrochemical device having the same.
US08765017B2
Gasification systems and associated processes are disclosed herein. In one embodiment, a gasification process includes simultaneously supplying a carbonaceous material and steam to a gasifier, the gasifier containing a liquid volume containing at least about 10% by weight of iron oxide (FexOy where x and y are positive integers). The gasification process also includes performing a gasification reaction between the carbonaceous material and steam in the liquid volume, facilitating the gasification reaction with the iron oxide in the liquid volume, and producing a gas from the gasification reaction, the gas containing carbon monoxide (CO) and hydrogen (H2).
US08765007B2
A method of evaluating a positive electrode active material has a density ratio-determining step of determining a ratio of an apparent density Da of the positive electrode active material to a theoretical density Db of the positive electrode active material. For example, when the positive electrode active material contains no closed space in the positive electrode active material, such as closed pores of the positive electrode active material, the ratio (Da/Db) of the apparent density Da of the positive electrode active material to the theoretical density Db of the positive electrode active material will be a value close to 1; however, the more the closed space such as the closed pores exists in the positive electrode active material, the smaller the ratio (Da/Db). Thus, the ratio (Da/Db) can serve as an indicator for measuring the degree of density of the positive electrode active material.
US08765001B2
Monocrystalline semiconductor substrates are textured with alkaline solutions to form pyramid structures on their surfaces to reduce incident light reflectance and improve light absorption of the wafers. The alkaline baths include hydantoin compounds and derivatives thereof in combination with alkoxylated glycols to inhibit the formation of flat areas between pyramid structures to improve the light absorption.
US08764972B2
Contact of a crude feed with one or more catalysts produces a total product that includes a crude product. The crude product is a liquid mixture at 25° C. and 0.101 MPa. The one or more catalyst may include an uncalcined catalyst. One or more other properties of the crude product may be changed by at least 10% relative to the respective properties of the crude feed.
US08764968B2
A technique for nanodevice is provided. A reservoir is filled with an ionic fluid. A membrane separates the reservoir, and the membrane includes electrode layers separated by insulating layers in which the electrode layers have an organic coating. A nanopore is formed through the membrane, and the organic coating on the electrode layers forms transient bonds to a base of a molecule in the nanopore. When a first voltage is applied to the electrode layers a tunneling current is generated by the base in the nanopore, and the tunneling current travels through the transient bonds formed to the base to be measured as a current signature for distinguishing the base.
US08764967B2
A method and system for regenerating used cooking oil in which the used cooking oil is introduced into a cooking oil regenerator, which includes an electrochemical device having a high temperature proton exchange membrane disposed between an anode electrode and a cathode electrode. A voltage is applied between the anode electrode and the cathode electrode using an external electricity source, producing regenerated cooking oil.
US08764966B2
Both the reaction of hydride-forming compositions with hydrogen to form hydrides, and the decomposition of such hydrides to release hydrogen may be promoted electrochemically. These reactions may be conducted reversibly, and if performed in a suitable cell, the cell will serve as a hydrogen storage and release device.
US08764964B2
A system for forming metal hydroxide from a metal carbonate utilizes a water electrolysis cell having an acid-producing anode and a hydroxyl-producing cathode immersed in a water solution of sufficient ionic content to allow an electric current to pass between the hydroxyl-producing cathode and the acid-producing anode. A metal carbonate is placed in close proximity to the acid-producing anode. A direct current electrical voltage is provided across the acid-producing anode and the hydroxyl-producing cathode sufficient to generate acid at the acid-producing anode and hydroxyl ions at the hydroxyl-producing cathode. The acid dissolves at least part of the metal carbonate into metal and carbonate ions allowing the metal ions to travel toward the hydroxyl-producing cathode and to combine with the hydroxyl ions to form the metal hydroxide. The carbonate ions travel toward the acid-producing anode and form carbonic acid and/or water and carbon dioxide.
US08764961B2
A method and apparatus for selectively controlling deposition rate of conductive material during an electroplating process. Dopants are predominantly incorporated into a conductive seed layer on field regions of a substrate prior to filling openings in the field regions by electroplating. A substrate is positioned in one or more processing chambers, and barrier and conductive seed layers formed. A dopant precursor is provided to the chamber and ionized, with or without voltage bias. The dopant predominantly incorporates into the conductive seed layer on the field regions. Electrical conductivity of the conductive seed layer on the field regions is reduced relative to that of the conductive seed layer in the openings, resulting in low initial deposition rate of metal on the field regions during electroplating, and little or no void formation in the metal deposited in the openings.
US08764958B2
A bi-state-switch low-voltage fabrication technique is able to be used to construct microfluidic systems leveraging well-established low-voltage semiconductor fabrication technologies to achieve high-voltage droplet actuation applications with lower costs, smaller device sizes, and also less time. Also, the electrode cells are able to be made using the well-established low-voltage CMOS fabrication technologies, which can be used to make large-scale integrated microelectronics and microfluidics.
US08764932B2
A mounting system for fixation of two objects includes a single-component aerobic adhesive and a metered amount of moisture added to the adhesive prior to using the adhesive to fixate the objects. The adhesive with the moisture is hardenable while the objects are glued together.